DK0896544T3 - Kombination af en somatostatinanalog og en rapamycin - Google Patents

Kombination af en somatostatinanalog og en rapamycin

Info

Publication number: DK0896544T3
Authority: DK; Denmark
Prior art keywords: combination; rapamycin; somatostatin analogue; somatostatin; analogue
Prior art date: 1996-06-11

Application number

DK97928175T

Other languages

Danish (da)

English (en)

Inventor

Gisbert Weckbecker

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-11

Filing date

1997-06-11

Publication date

2003-05-05

1996-06-11 Priority claimed from GBGB9612171.0A external-priority patent/GB9612171D0/en

1996-09-16 Priority claimed from GBGB9619310.7A external-priority patent/GB9619310D0/en

1997-06-11 Application filed by Novartis Ag filed Critical Novartis Ag

2003-05-05 Application granted granted Critical

2003-05-05 Publication of DK0896544T3 publication Critical patent/DK0896544T3/da

Links

ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 title abstract 2
QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 title abstract 2
229960002930 sirolimus Drugs 0.000 title abstract 2
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title abstract 2
229940075620 somatostatin analogue Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK97928175T 1996-06-11 1997-06-11 Kombination af en somatostatinanalog og en rapamycin DK0896544T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9612171.0A GB9612171D0 (en)	1996-06-11	1996-06-11	Organic compounds
GBGB9619310.7A GB9619310D0 (en)	1996-09-16	1996-09-16	Organic compounds
PCT/EP1997/003036 WO1997047317A1 (en)	1996-06-11	1997-06-11	Combination of a somatostatin analogue and a rapamycin

Publications (1)

Publication Number	Publication Date
DK0896544T3 true DK0896544T3 (da)	2003-05-05

Family

ID=26309485

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97928175T DK0896544T3 (da)	1996-06-11	1997-06-11	Kombination af en somatostatinanalog og en rapamycin

Country Status (10)

Country	Link
US (1)	US6362164B1 (es)
EP (1)	EP0896544B1 (es)
JP (1)	JP3784418B2 (es)
AT (1)	ATE233098T1 (es)
AU (1)	AU3257297A (es)
CA (1)	CA2249439C (es)
DE (1)	DE69719320T2 (es)
DK (1)	DK0896544T3 (es)
ES (1)	ES2193379T3 (es)
WO (1)	WO1997047317A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK1165613T3 (da)	1999-03-29	2008-08-25	Procter & Gamble	Melanocortinreceptorligander
ES2167189B1 (es) *	1999-12-17	2003-04-01	Lipotec Sa	Formulacion farmaceutica estable para la administracion intravenosa o intramuscular, de principios activos peptidicos
EP2298299A3 (en) *	2000-01-14	2012-02-29	The Trustees Of The University Of Pennsylvania	O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders
AU2011226833B9 (en) *	2001-02-19	2014-07-03	Novartis Ag	Cancer treatment
PL409579A1 (pl) *	2001-02-19	2015-03-02	Novartis Ag	Leczenie raka
AU2016206379B2 (en) *	2001-02-19	2017-09-14	Novartis Ag	Cancer Treatment
AU2005201004A1 (en) *	2001-02-19	2005-03-24	Novartis Ag	Cancer treatment
FI20031454A0 (fi)	2003-10-06	2003-10-06	Juvantia Pharma Ltd Oy	Selektiivisiä somatostatiinireseptori 1 ja/tai 4 -agonisteja ja -antagonisteja
EP1522311A1 (fr) *	2003-10-10	2005-04-13	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Utilisation de la somatostine ou d'un de ses analogues pour préparer un médicament destiné à réguler la réserve folliculaire ovarienne chez la femme non ménopausée
CA2562164A1 (en) *	2004-04-27	2005-11-10	Wyeth	Labeling of rapamycin using rapamycin-specific methylases
WO2006115509A2 (en)	2004-06-24	2006-11-02	Novartis Vaccines And Diagnostics Inc.	Small molecule immunopotentiators and assays for their detection
PT1787658E (pt)	2005-11-10	2012-06-22	Chemi Spa	Formulações de libertação sustentada de análogos de somatostatina inibidores da hormona do crescimento
RU2487711C2 (ru) *	2005-11-21	2013-07-20	Новартис Аг	Лечение нейроэндокринных опухолей
JP2009254391A (ja) *	2006-07-18	2009-11-05	Tetsuhiko Katsumata	ゴルフのボールマーカー用ホルダー及びアクセサリー
EP2597992B1 (en)	2010-07-29	2015-10-07	Linak A/S	Lifting column preferably for height-adjustable tables
AU2012278813B2 (en) *	2011-07-07	2016-09-08	Research Cancer Institute Of America	Systems, methods, and formulations for treating cancer
US8933078B2 (en)	2011-07-14	2015-01-13	Research Cancer Institute Of America	Method of treating cancer with combinations of histone deacetylase inhibitors (HDAC1) substances
WO2018157081A1 (en)	2017-02-27	2018-08-30	Research Cancer Institute Of America	Compositions, methods, systems and/or kits for preventing and/or treating neoplasms
US11369585B2 (en)	2017-03-17	2022-06-28	Research Cancer Institute Of America	Compositions, methods, systems and/or kits for preventing and/or treating neoplasms
US12213958B2 (en)	2017-11-17	2025-02-04	Research Cancer Institute Of America	Compositions, methods, systems and/or kits for preventing and/or treating neoplasms
JP7099717B2 (ja)	2019-09-30	2022-07-12	株式会社理研バイオ	ソマトスタチン受容体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2239178B (en) *	1987-07-10	1991-11-27	Sandoz Ltd	Somatostatin analogues for the treatment of breast cancer
GB9125660D0 (en)	1991-12-03	1992-01-29	Smithkline Beecham Plc	Novel compound

1997
- 1997-06-11 AT AT97928175T patent/ATE233098T1/de active
- 1997-06-11 ES ES97928175T patent/ES2193379T3/es not_active Expired - Lifetime
- 1997-06-11 US US09/194,957 patent/US6362164B1/en not_active Expired - Lifetime
- 1997-06-11 WO PCT/EP1997/003036 patent/WO1997047317A1/en not_active Ceased
- 1997-06-11 JP JP50120398A patent/JP3784418B2/ja not_active Expired - Lifetime
- 1997-06-11 DK DK97928175T patent/DK0896544T3/da active
- 1997-06-11 CA CA002249439A patent/CA2249439C/en not_active Expired - Lifetime
- 1997-06-11 AU AU32572/97A patent/AU3257297A/en not_active Abandoned
- 1997-06-11 DE DE69719320T patent/DE69719320T2/de not_active Expired - Lifetime
- 1997-06-11 EP EP97928175A patent/EP0896544B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US6362164B1 (en)	2002-03-26
EP0896544B1 (en)	2003-02-26
JP2000514415A (ja)	2000-10-31
DE69719320T2 (de)	2003-12-11
WO1997047317A1 (en)	1997-12-18
ATE233098T1 (de)	2003-03-15
JP3784418B2 (ja)	2006-06-14
CA2249439A1 (en)	1997-12-18
EP0896544A1 (en)	1999-02-17
CA2249439C (en)	2009-09-08
AU3257297A (en)	1998-01-07
ES2193379T3 (es)	2003-11-01
DE69719320D1 (de)	2003-04-03

Publication	Publication Date	Title
DK0896544T3 (da)	2003-05-05	Kombination af en somatostatinanalog og en rapamycin
PT914103E (pt)	2006-09-29	Tratamento de uma hemoglobinopatia
ATE206413T1 (de)	2001-10-15	Substituierte oxazolidine als calpain und/oder cathepsin b-hemmer
DE59409721D1 (de)	2001-05-17	Formulierungen
ES2191830T3 (es)	2003-09-16	Inhibidores de trombina.
DE59608538D1 (de)	2002-02-07	Bohr- und/oder Meisselgerät
NO305398B1 (no)	1999-05-25	Tiosubstituerte nitrogenholdige heterocykliske fosfonatforbindelser, og anvendelser derav
FI953483A7 (fi)	1995-09-15	Jätekaasuöljyn käsittely
FI945355L (fi)	1995-05-17	Läpivienti
KR950704653A (ko)	1995-11-20	독성 폐기물의 처리(treatment of toxic wastes)
NO912091D0 (no)	1991-05-30	Fremgangsmaate for inhibering av avleiringer og avleiringsinhiberende sammensetning.
DK206391A (da)	1993-06-30	Slambehandling
DE69625230D1 (de)	2003-01-16	Thrombininhibitoren
DE59711737D1 (de)	2004-08-05	Gewölbtes Metall-Keramik-Substrat
FI943344A7 (fi)	1995-01-15	Urinaali
DE59812757D1 (de)	2005-06-02	Substituierte tetrahydro-naphtaline und analoge verbindungen
FR2711511B1 (fr)	1996-01-26	Prothèses métatarso-phalangiennes temporaires.
KR950014549U (ko)	1995-06-17	방충창 이탈방지용 리드피스
KR950003749U (ko)	1995-02-17	폐수 처리기
FI94161B (fi)	1995-04-13	Luukkurakenne
KR950003750U (ko)	1995-02-17	폐수 처리기
KR950012058U (ko)	1995-05-16	다단식 소각장치
KR940019046U (ko)	1994-08-16	마스킹 재
KR940019393U (ko)	1994-08-19	하수관
KR940026912U (ko)	1994-12-09	하수관