DK0920441T3 - 7alfa-(epsilon-aminoalkyl)-estratriener, fremgangsmåde til deres fremstilling, farmaceutiske præparater, som indeholder disse 7-alfa-(epsilon-aminoalkyl)-estratriener, samt deres anvendelse til fremstilling af lægemidler - Google Patents

7alfa-(epsilon-aminoalkyl)-estratriener, fremgangsmåde til deres fremstilling, farmaceutiske præparater, som indeholder disse 7-alfa-(epsilon-aminoalkyl)-estratriener, samt deres anvendelse til fremstilling af lægemidler

Info

Publication number
DK0920441T3
DK0920441T3 DK97943814T DK97943814T DK0920441T3 DK 0920441 T3 DK0920441 T3 DK 0920441T3 DK 97943814 T DK97943814 T DK 97943814T DK 97943814 T DK97943814 T DK 97943814T DK 0920441 T3 DK0920441 T3 DK 0920441T3
Authority
DK
Denmark
Prior art keywords
estratrienes
epsilon
aminoalkyl
7alpha
pharmaceuticals
Prior art date
Application number
DK97943814T
Other languages
Danish (da)
English (en)
Inventor
Josef Heindi
Nikolaus Heinrich
Hermann Kuenzer
Gerhard Sauer
Christa Hegelehartung
Rosemarie Lichtner
Karsten Parczyk
Rolf Bohlmann
Dieter Bittler
Helmut Hofmeister
Yukishige Nishino
Martin Schneider
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0920441T3 publication Critical patent/DK0920441T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK97943814T 1996-08-20 1997-08-20 7alfa-(epsilon-aminoalkyl)-estratriener, fremgangsmåde til deres fremstilling, farmaceutiske præparater, som indeholder disse 7-alfa-(epsilon-aminoalkyl)-estratriener, samt deres anvendelse til fremstilling af lægemidler DK0920441T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19635525A DE19635525A1 (de) 1996-08-20 1996-08-20 7alpha-(xi-Aminoalkyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha(xi-Aminoalkyl-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln
PCT/EP1997/004517 WO1998007740A1 (de) 1996-08-20 1997-08-20 7α-(κ-AMINOALKYL)-ESTRATRIENE, VERFAHREN ZU DEREN HERSTELLUNG, PHARMAZEUTISCHE PRÄPARATE, DIE DIESE 7α-(κ-AMINOALKYL)-ESTRATRIENE ENTHALTEN SOWIE DEREN VERWENDUNG ZUR HERSTELLUNG VON ARZNEIMITTELN

Publications (1)

Publication Number Publication Date
DK0920441T3 true DK0920441T3 (da) 2003-05-26

Family

ID=7804367

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97943814T DK0920441T3 (da) 1996-08-20 1997-08-20 7alfa-(epsilon-aminoalkyl)-estratriener, fremgangsmåde til deres fremstilling, farmaceutiske præparater, som indeholder disse 7-alfa-(epsilon-aminoalkyl)-estratriener, samt deres anvendelse til fremstilling af lægemidler

Country Status (29)

Country Link
EP (1) EP0920441B1 (pl)
JP (1) JP2001503024A (pl)
KR (1) KR20000068261A (pl)
CN (1) CN1231670A (pl)
AR (1) AR009278A1 (pl)
AT (1) ATE231882T1 (pl)
AU (1) AU728843B2 (pl)
BG (1) BG62972B1 (pl)
BR (1) BR9711328A (pl)
CA (1) CA2263708A1 (pl)
CZ (1) CZ57999A3 (pl)
DE (2) DE19635525A1 (pl)
DK (1) DK0920441T3 (pl)
EA (1) EA001577B1 (pl)
EE (1) EE04021B1 (pl)
ES (1) ES2191857T3 (pl)
HU (1) HUP9903106A3 (pl)
IL (1) IL128601A (pl)
IS (1) IS4976A (pl)
NO (1) NO315655B1 (pl)
NZ (1) NZ334277A (pl)
PL (1) PL186309B1 (pl)
PT (1) PT920441E (pl)
SK (1) SK18899A3 (pl)
TR (1) TR199900432T2 (pl)
TW (1) TW552267B (pl)
UA (1) UA50792C2 (pl)
WO (1) WO1998007740A1 (pl)
ZA (1) ZA977482B (pl)

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US6503896B1 (en) 1997-12-24 2003-01-07 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
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DE10019171A1 (de) * 2000-04-07 2001-10-18 Schering Ag Zusammensetzungen zur Verwendung als Penetrationsverstärker in transdermalen Formulierungen für hoch lipophile Wirkstoffe
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DE10159217A1 (de) * 2001-11-27 2003-06-05 Schering Ag 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
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DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de) 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
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ES2970222T3 (es) 2014-06-18 2024-05-27 Sage Therapeutics Inc Oxiesteroles y procedimientos de uso de los mismos
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Also Published As

Publication number Publication date
ZA977482B (en) 1998-02-23
BG103185A (en) 1999-11-30
NZ334277A (en) 2000-10-27
CN1231670A (zh) 1999-10-13
PT920441E (pt) 2003-06-30
EE9900075A (et) 1999-10-15
TR199900432T2 (xx) 1999-04-21
PL186309B1 (pl) 2003-12-31
NO990793L (no) 1999-04-20
EA001577B1 (ru) 2001-06-25
AU4552097A (en) 1998-03-06
IS4976A (is) 1999-02-11
EP0920441A1 (de) 1999-06-09
ATE231882T1 (de) 2003-02-15
CZ57999A3 (cs) 1999-08-11
EE04021B1 (et) 2003-04-15
WO1998007740A1 (de) 1998-02-26
SK18899A3 (en) 1999-08-06
NO315655B1 (no) 2003-10-06
NO990793D0 (no) 1999-02-19
IL128601A (en) 2003-07-31
UA50792C2 (uk) 2002-11-15
BG62972B1 (bg) 2000-12-29
BR9711328A (pt) 1999-08-17
TW552267B (en) 2003-09-11
AR009278A1 (es) 2000-04-12
EP0920441B1 (de) 2003-01-29
DE19635525A1 (de) 1998-02-26
KR20000068261A (ko) 2000-11-25
ES2191857T3 (es) 2003-09-16
PL331863A1 (en) 1999-08-16
DE59709239D1 (de) 2003-03-06
CA2263708A1 (en) 1998-02-26
HUP9903106A2 (hu) 2000-03-28
JP2001503024A (ja) 2001-03-06
HUP9903106A3 (en) 2000-05-29
AU728843B2 (en) 2001-01-18
EA199900210A1 (ru) 1999-08-26
IL128601A0 (en) 2000-01-31

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