DK0966477T3 - 3'-N-oxid, 3'-N-dimethylamin, 9-oxim-erythromycin A-derivater - Google Patents

3'-N-oxid, 3'-N-dimethylamin, 9-oxim-erythromycin A-derivater

Info

Publication number
DK0966477T3
DK0966477T3 DK98904822T DK98904822T DK0966477T3 DK 0966477 T3 DK0966477 T3 DK 0966477T3 DK 98904822 T DK98904822 T DK 98904822T DK 98904822 T DK98904822 T DK 98904822T DK 0966477 T3 DK0966477 T3 DK 0966477T3
Authority
DK
Denmark
Prior art keywords
erythromycin
dimethylamine
oxime
derivatives
oxide
Prior art date
Application number
DK98904822T
Other languages
Danish (da)
English (en)
Inventor
Yi-Yin Ku
David A Riley
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK0966477T3 publication Critical patent/DK0966477T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98904822T 1997-02-13 1998-02-03 3'-N-oxid, 3'-N-dimethylamin, 9-oxim-erythromycin A-derivater DK0966477T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/800,009 US5864023A (en) 1997-02-13 1997-02-13 3'-N'oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives
PCT/US1998/001929 WO1998035976A1 (fr) 1997-02-13 1998-02-03 Derives de 3'-n-oxyde, 3'-n-dimethylamine, 9-oxime erythromycine a

Publications (1)

Publication Number Publication Date
DK0966477T3 true DK0966477T3 (da) 2004-02-23

Family

ID=25177295

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98904822T DK0966477T3 (da) 1997-02-13 1998-02-03 3'-N-oxid, 3'-N-dimethylamin, 9-oxim-erythromycin A-derivater

Country Status (25)

Country Link
US (1) US5864023A (fr)
EP (1) EP0966477B1 (fr)
JP (1) JP2001512456A (fr)
KR (1) KR100561326B1 (fr)
CN (1) CN1326865C (fr)
AR (1) AR012032A1 (fr)
AT (1) ATE252108T1 (fr)
AU (1) AU725274B2 (fr)
BG (1) BG64099B1 (fr)
BR (1) BR9807349A (fr)
CA (1) CA2279932C (fr)
CZ (1) CZ294481B6 (fr)
DE (1) DE69818977T2 (fr)
DK (1) DK0966477T3 (fr)
ES (1) ES2212266T3 (fr)
HU (1) HUP0001330A3 (fr)
IL (1) IL130697A0 (fr)
NO (1) NO993876L (fr)
NZ (1) NZ336482A (fr)
PL (1) PL187357B1 (fr)
PT (1) PT966477E (fr)
SK (1) SK284157B6 (fr)
TR (1) TR199901874T2 (fr)
WO (1) WO1998035976A1 (fr)
ZA (1) ZA98986B (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100317907B1 (ko) * 1998-11-24 2001-12-24 김 완 주 신규한 중간체, 이를 이용한 마크로라이드계 항생제의제조방법
US6437106B1 (en) 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
KR20010008496A (ko) * 1999-07-01 2001-02-05 유충식 6-오-메틸 에리트로마이신의 제조방법
KR100336447B1 (ko) * 1999-11-24 2002-05-15 민경윤 클라리스로마이신의 개선된 제조방법
AU783055B2 (en) * 1999-12-16 2005-09-22 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin polymorphs and novel polymorph IV
RU2002118308A (ru) 2000-01-11 2004-02-20 Тева Фамэситикл Индастрис Лтд. (Il) Способы получения полиморфных модификаций кларитромицина
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) * 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
HUP0302466A2 (hu) * 2000-02-29 2003-11-28 Teva Pharmaceutical Industries Ltd. Eljárások clarithromycin, clarithromycin intermedier, gyakorlatilag oximmentes clarithromycin és ezt tartalmazó gyógyszerkészítmény előállítására
ATE297941T1 (de) * 2000-03-15 2005-07-15 Hanmi Pharm Ind Co Ltd Verfahren zur herstellung von einer kristallinen form ii von clarythromycin
KR20000037126A (ko) * 2000-04-08 2000-07-05 김용규 6-메틸 에리스로마이신 ａ의 제조방법
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
CA2533358C (fr) * 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Produit antibiotique, utilisation et formulation associees
WO2005009365A2 (fr) * 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Produit antibiotique, son utilisation et sa formulation
AU2004258953B2 (en) * 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
US8758820B2 (en) * 2003-08-11 2014-06-24 Shionogi Inc. Robust pellet
JP2007502294A (ja) * 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8246996B2 (en) * 2003-08-29 2012-08-21 Shionogi Inc. Antibiotic product, use and formulation thereof
JP2007513869A (ja) * 2003-09-15 2007-05-31 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP2007517039A (ja) * 2003-12-24 2007-06-28 アドバンシス ファーマスーティカル コーポレイション 変性放出製剤の吸収増強
US8715727B2 (en) * 2004-07-02 2014-05-06 Shionogi Inc. Tablet for pulsed delivery
US7694523B2 (en) * 2004-07-19 2010-04-13 Earthrenew, Inc. Control system for gas turbine in material treatment unit
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
WO2009023191A2 (fr) * 2007-08-09 2009-02-19 Teva Pharmaceutical Industries Ltd. Procédé amélioré de préparation de la clarithromycine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
US4670549A (en) * 1985-03-18 1987-06-02 Taisho Pharmaceutical Co., Ltd. Method for selective methylation of erythromycin a derivatives
JPS61229895A (ja) * 1985-04-03 1986-10-14 Nippon Zeon Co Ltd 保護化デス−ｎ−メチルエリスロマイシン誘導体
EP0254534A3 (fr) * 1986-07-24 1991-04-17 William S. Robinson Dérivés d'érythromycine et compositions et leur emploi pour inhiber les réplications et maladies virales
DE3782994T2 (de) * 1986-09-18 1993-04-08 Taisho Pharma Co Ltd Erythromycin-a-derivate und verfahren zu ihrer herstellung.
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
JP2751385B2 (ja) * 1988-05-19 1998-05-18 大正製薬株式会社 エリスロマイシンａオキシム及びその塩の製造方法

Also Published As

Publication number Publication date
ATE252108T1 (de) 2003-11-15
SK97499A3 (en) 2000-01-18
BG103673A (en) 2000-02-29
PL335301A1 (en) 2000-04-10
AU6260898A (en) 1998-09-08
DE69818977T2 (de) 2004-08-12
BR9807349A (pt) 2000-04-25
CZ270499A3 (cs) 1999-11-17
DE69818977D1 (en) 2003-11-20
KR100561326B1 (ko) 2006-03-16
AR012032A1 (es) 2000-09-27
IL130697A0 (en) 2000-06-01
HUP0001330A2 (hu) 2000-08-28
AU725274B2 (en) 2000-10-12
EP0966477B1 (fr) 2003-10-15
KR20000070985A (ko) 2000-11-25
TR199901874T2 (xx) 2000-04-21
NO993876D0 (no) 1999-08-11
WO1998035976A1 (fr) 1998-08-20
ZA98986B (en) 1998-08-05
CN1326865C (zh) 2007-07-18
NZ336482A (en) 2001-02-23
CN1246864A (zh) 2000-03-08
BG64099B1 (bg) 2003-12-31
JP2001512456A (ja) 2001-08-21
CA2279932C (fr) 2008-04-22
PL187357B1 (pl) 2004-06-30
US5864023A (en) 1999-01-26
HUP0001330A3 (en) 2000-09-28
CZ294481B6 (cs) 2005-01-12
PT966477E (pt) 2004-03-31
CA2279932A1 (fr) 1998-08-20
SK284157B6 (sk) 2004-10-05
EP0966477A1 (fr) 1999-12-29
ES2212266T3 (es) 2004-07-16
NO993876L (no) 1999-08-11

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