DK0970077T3 - Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner - Google Patents

Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner

Info

Publication number
DK0970077T3
DK0970077T3 DK98916974T DK98916974T DK0970077T3 DK 0970077 T3 DK0970077 T3 DK 0970077T3 DK 98916974 T DK98916974 T DK 98916974T DK 98916974 T DK98916974 T DK 98916974T DK 0970077 T3 DK0970077 T3 DK 0970077T3
Authority
DK
Denmark
Prior art keywords
thiazolidinediones
novel
preparation
improved process
improved
Prior art date
Application number
DK98916974T
Other languages
Danish (da)
English (en)
Inventor
Hans-Peter Wolff
Ernst-Christian Witte
Hans-Frieder Kuehnle
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Application granted granted Critical
Publication of DK0970077T3 publication Critical patent/DK0970077T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK98916974T 1997-03-20 1998-03-17 Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner DK0970077T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19711616A DE19711616A1 (de) 1997-03-20 1997-03-20 Verbessertes Verfahren zur Herstellung von Thiazolidindionen
PCT/EP1998/001535 WO1998042704A1 (de) 1997-03-20 1998-03-17 Verbessertes verfahren zur herstellung von thiazolidindionen und neue thiazolidindione

Publications (1)

Publication Number Publication Date
DK0970077T3 true DK0970077T3 (da) 2003-09-01

Family

ID=7824011

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98916974T DK0970077T3 (da) 1997-03-20 1998-03-17 Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner

Country Status (25)

Country Link
US (2) US6258832B1 (sr)
EP (1) EP0970077B1 (sr)
JP (2) JP3484200B2 (sr)
KR (1) KR100340353B1 (sr)
CN (1) CN1105718C (sr)
AR (1) AR012124A1 (sr)
AT (1) ATE240324T1 (sr)
AU (1) AU726048B2 (sr)
BR (1) BR9808029A (sr)
CA (1) CA2285208C (sr)
DE (2) DE19711616A1 (sr)
DK (1) DK0970077T3 (sr)
ES (1) ES2198053T3 (sr)
HU (1) HUP0001551A3 (sr)
IL (1) IL131772A (sr)
NO (1) NO313292B1 (sr)
NZ (1) NZ337608A (sr)
PL (1) PL192201B1 (sr)
PT (1) PT970077E (sr)
RS (1) RS49771B (sr)
RU (1) RU2181724C2 (sr)
TR (1) TR199902197T2 (sr)
TW (1) TW487707B (sr)
WO (1) WO1998042704A1 (sr)
ZA (1) ZA982326B (sr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1078923B1 (en) 1999-08-02 2006-03-08 F. Hoffmann-La Roche Ag Process for the preparation of benzothiophene derivatives
US6531609B2 (en) 2000-04-14 2003-03-11 Hoffmann-La Roche Inc. Process for the preparation of thiazolidinedione derivatives
FR2820741A1 (fr) * 2001-02-14 2002-08-16 Ppg Sipsy Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine
FR2820742B1 (fr) * 2001-02-14 2005-03-11 Ppg Sipsy Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine
US7323481B2 (en) 2001-04-06 2008-01-29 Hoffmann-La Roche Inc. Thiazolidinediones alone or in combination with other therapeutic agents for inhibiting or reducing tumour growth
AU2002342244B2 (en) 2001-05-15 2005-06-16 F. Hoffmann-La Roche Ag Carboxylic acid substituted oxazole derivatives for use as PPAR-alpha and -gamma activators in the treatment of diabetes
ES2291688T3 (es) * 2002-07-03 2008-03-01 F. Hoffmann-La Roche Ag Derivados de oxazol y su empleo como sensibilizadores a la insulina.
ES2350340T3 (es) * 2002-08-30 2011-01-21 F. Hoffmann-La Roche Ag Nuevos compuestos de 2-aril-tiazol como agonistas de pparalfa y ppargamma.
NZ537979A (en) * 2002-09-12 2007-08-31 Hoffmann La Roche N-substituted-1H-indol-5-propionic acid compounds as PPAR agonists useful for the treatment of diabetes
ATE405560T1 (de) * 2002-11-25 2008-09-15 Hoffmann La Roche Indolderivaten
WO2005000844A1 (en) * 2003-06-26 2005-01-06 F. Hoffmann-La Roche Ag Process for the preparation of insulin sensitizer and intermediate compound thereof
US11852360B2 (en) 2019-12-10 2023-12-26 Lg Electronics Inc. Air management apparatus or device

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
WO1986007056A1 (en) 1985-05-21 1986-12-04 Pfizer Inc. Hypoglycemic thiazolidinediones
GB8713861D0 (en) 1987-06-13 1987-07-15 Beecham Group Plc Compounds
SG59988A1 (en) 1987-09-04 1999-02-22 Beecham Group Plc Substituted thiazolidinedione derivatives
US5330998A (en) 1988-03-08 1994-07-19 Pfizer Inc. Thiazolidinedione derivatives as hypoglycemic agents
WO1989008652A1 (en) 1988-03-08 1989-09-21 Pfizer Inc. Thiazolidinedione derivatives as hypoglycemic agents
WO1989008650A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Thiazolidinedione hypoglycemic agents
MX15171A (es) 1988-03-08 1993-05-01 Pfizer Derivados de tiazolidinodiona hipoglicemicos
ATE205206T1 (de) * 1990-04-27 2001-09-15 Sankyo Co Benzylidenthiazolidinderivate, ihre herstellung und ihre anwendung als lipidperoxid-inhibitoren
FI930772A0 (fi) 1990-08-23 1993-02-22 Pfizer Hydroxiureaderivat som saenker glugosnivao i blodet
US5585495A (en) 1991-12-20 1996-12-17 The Upjohn Company Reduction method for substituted 5-methylene-thiazolidinediones
FR2688220A1 (fr) 1992-03-06 1993-09-10 Adir Nouveaux derives de thiazolidine-2,4-dione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4317320A1 (de) * 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
ES2131301T3 (es) 1993-12-27 1999-07-16 Japan Tobacco Inc Derivado de isoxazolidindiona y su utilizacion.

Also Published As

Publication number Publication date
CA2285208A1 (en) 1998-10-01
KR20000076344A (ko) 2000-12-26
NO994505D0 (no) 1999-09-17
ZA982326B (en) 1999-09-20
YU46699A (sh) 2002-06-19
KR100340353B1 (ko) 2002-06-12
TR199902197T2 (xx) 1999-12-21
AR012124A1 (es) 2000-09-27
CA2285208C (en) 2003-07-08
NO994505L (no) 1999-11-17
US20010008902A1 (en) 2001-07-19
IL131772A0 (en) 2001-03-19
IL131772A (en) 2002-09-12
RU2181724C2 (ru) 2002-04-27
RS49771B (sr) 2008-06-05
AU7036198A (en) 1998-10-20
HK1025965A1 (en) 2000-12-01
PT970077E (pt) 2003-08-29
ATE240324T1 (de) 2003-05-15
WO1998042704A1 (de) 1998-10-01
CN1105718C (zh) 2003-04-16
PL335903A1 (en) 2000-05-22
DE59808365D1 (de) 2003-06-18
HUP0001551A3 (en) 2000-12-28
JP2004067697A (ja) 2004-03-04
PL192201B1 (pl) 2006-09-29
NZ337608A (en) 2001-05-25
US6258832B1 (en) 2001-07-10
JP3484200B2 (ja) 2004-01-06
BR9808029A (pt) 2000-03-08
HUP0001551A2 (hu) 2000-11-28
DE19711616A1 (de) 1998-09-24
CN1250448A (zh) 2000-04-12
EP0970077A1 (de) 2000-01-12
NO313292B1 (no) 2002-09-09
US6441185B2 (en) 2002-08-27
AU726048B2 (en) 2000-10-26
ES2198053T3 (es) 2004-01-16
JP2000512312A (ja) 2000-09-19
EP0970077B1 (de) 2003-05-14
TW487707B (en) 2002-05-21

Similar Documents

Publication Publication Date Title
DK0770615T3 (da) Fremgangsmåde til fremstilling af dihalogenazolopyrimidiner
NO980707D0 (no) Fremgangsmåte til fremstilling av kopolymerer
DK1038008T3 (da) Fremgangsmåde til fremstilling af EGIII-lignende enzymer
DK1044969T3 (da) Fremgangsmåde og mellemprodukter til fremstilling af anti-cancer forbindelser
DK0831098T3 (da) Mellemprodukter og fremgangsmåde til fremstilling af olanzapin
NO20012963L (no) Fremgangsmåte for fremstilling av 3-alkanoylindoler og 3- alkylindoler
DK0909270T3 (da) Fremgangsmåde til fremstilling af 2,4-dihydroxypyridin og 2,4-dihydroxy-3-nitropyridin
DK0839138T3 (da) Fremgangsmåde til fremstilling af N-substituerede 3-hydroxypyrazoler
DK0970077T3 (da) Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner
DK0824517T3 (da) Fremgangsmåde til fremstilling af lercanidipinhydrochlorid
DK0805797T3 (da) Fremgangsmåde til fremstilling af N-aryl- og N-hetarylhydroxylaminer
DK0768310T3 (da) Fremgangsmåde til fremstilling af imidazo-benzodiazepin-derivater
DK0877738T3 (da) Fremgangsmåde til fremstilling af phenylimidazolidinderivater
DK0568072T3 (da) Fremgangsmåde til fremstilling af amidforbindelser og mikroorganisme til anvendelse deri
DK1028960T3 (da) Fremgangsmåde til fremstilling af thiazolidinedion
DK0946531T3 (da) Fremgangsmåde til fremstilling af thiazol-derivater
DK0946514T3 (da) Fremgangsmåde til fremstilling af n-substituerede 3-hydroxypyrazoler
DK0648738T3 (da) Fremgangsmåde til fremstilling af acetoacetarylamider
DK0648748T3 (da) Fremgangsmåde til fremstilling af 5-acetoacetylaminobenzimidazolon-2
DK1012152T3 (da) Fremgangsmåde til fremstilling af oxazaphosphorin-2-aminer
DK1023279T3 (da) Forbindelser og fremgangsmåde til fremstilling af substituerede 4-phenyl-4-cyanocyclohexansyrer
DK1036319T3 (da) Fremgangsmåde til opnåelse af L-dihydroorotsyre og anvendelse deraf
DK0899262T3 (da) Fremgangsmåde til fremstilling af heteroarylcarboxylamider og -estere
DK0721929T3 (da) Fremgangsmåde til fremstilling af hydroxyalkoxybenzophenoner
DK0388620T3 (da) Fremgangsmåde til fremstilling af o-carboxy-pyridyl- og o-carboxyquinolylimidazolinoner