DK0970077T3 - Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner - Google Patents

Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner

Info

Publication number
DK0970077T3
DK0970077T3 DK98916974T DK98916974T DK0970077T3 DK 0970077 T3 DK0970077 T3 DK 0970077T3 DK 98916974 T DK98916974 T DK 98916974T DK 98916974 T DK98916974 T DK 98916974T DK 0970077 T3 DK0970077 T3 DK 0970077T3
Authority
DK
Denmark
Prior art keywords
thiazolidinediones
novel
preparation
improved process
improved
Prior art date
Application number
DK98916974T
Other languages
Danish (da)
English (en)
Inventor
Hans-Peter Wolff
Ernst-Christian Witte
Hans-Frieder Kuehnle
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Application granted granted Critical
Publication of DK0970077T3 publication Critical patent/DK0970077T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK98916974T 1997-03-20 1998-03-17 Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner DK0970077T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19711616A DE19711616A1 (de) 1997-03-20 1997-03-20 Verbessertes Verfahren zur Herstellung von Thiazolidindionen
PCT/EP1998/001535 WO1998042704A1 (de) 1997-03-20 1998-03-17 Verbessertes verfahren zur herstellung von thiazolidindionen und neue thiazolidindione

Publications (1)

Publication Number Publication Date
DK0970077T3 true DK0970077T3 (da) 2003-09-01

Family

ID=7824011

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98916974T DK0970077T3 (da) 1997-03-20 1998-03-17 Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner

Country Status (25)

Country Link
US (2) US6258832B1 (sr)
EP (1) EP0970077B1 (sr)
JP (2) JP3484200B2 (sr)
KR (1) KR100340353B1 (sr)
CN (1) CN1105718C (sr)
AR (1) AR012124A1 (sr)
AT (1) ATE240324T1 (sr)
AU (1) AU726048B2 (sr)
BR (1) BR9808029A (sr)
CA (1) CA2285208C (sr)
DE (2) DE19711616A1 (sr)
DK (1) DK0970077T3 (sr)
ES (1) ES2198053T3 (sr)
HU (1) HUP0001551A3 (sr)
IL (1) IL131772A (sr)
NO (1) NO313292B1 (sr)
NZ (1) NZ337608A (sr)
PL (1) PL192201B1 (sr)
PT (1) PT970077E (sr)
RS (1) RS49771B (sr)
RU (1) RU2181724C2 (sr)
TR (1) TR199902197T2 (sr)
TW (1) TW487707B (sr)
WO (1) WO1998042704A1 (sr)
ZA (1) ZA982326B (sr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1078923B1 (en) 1999-08-02 2006-03-08 F. Hoffmann-La Roche Ag Process for the preparation of benzothiophene derivatives
US6531609B2 (en) * 2000-04-14 2003-03-11 Hoffmann-La Roche Inc. Process for the preparation of thiazolidinedione derivatives
FR2820741A1 (fr) * 2001-02-14 2002-08-16 Ppg Sipsy Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine
FR2820742B1 (fr) * 2001-02-14 2005-03-11 Ppg Sipsy Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine
CA2441941A1 (en) * 2001-04-06 2002-10-17 F. Hoffmann-La Roche Ag Thiazolidinediones alone or in combination with other therapeutic agents for inhibiting or reducing tumour growth
RU2278859C2 (ru) * 2001-05-15 2006-06-27 Ф.Хоффманн-Ля Рош Аг Замещенные карбоновыми кислотами оксазоловые производные в качестве ppar-альфа и гамма-активаторов при лечении диабета
PL374818A1 (en) * 2002-07-03 2005-10-31 F.Hoffmann-La Roche Ag Oxazole derivatives and their use as insulin sensitizers
ATE483699T1 (de) * 2002-08-30 2010-10-15 Hoffmann La Roche Neue 2-arylthiazolverbindungen als ppar-alpha und gamma agonisten
WO2004024726A1 (en) * 2002-09-12 2004-03-25 F. Hoffmann-La Roche Ag N-substituted-1h-indol-5-propionic acid compounds as ppar agonists useful for the treatment of diabetes
DE60323130D1 (de) * 2002-11-25 2008-10-02 Hoffmann La Roche Indolderivaten
CA2530309A1 (en) * 2003-06-26 2005-01-06 F. Hoffmann-La Roche Ag Process for the preparation of insulin sensitizer and intermediate compound thereof
US12196431B2 (en) * 2019-12-10 2025-01-14 Lg Electronics Inc. Air management apparatus or device

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
WO1986007056A1 (en) 1985-05-21 1986-12-04 Pfizer Inc. Hypoglycemic thiazolidinediones
GB8713861D0 (en) 1987-06-13 1987-07-15 Beecham Group Plc Compounds
ATE186724T1 (de) * 1987-09-04 1999-12-15 Beecham Group Plc Substituierte thiazolidindionderivate
US5330998A (en) 1988-03-08 1994-07-19 Pfizer Inc. Thiazolidinedione derivatives as hypoglycemic agents
FI904414A7 (fi) 1988-03-08 1990-09-07 Pfizer Tiatsolidiinidioni-hypoglykeemisesti vaikuttavat aineet
WO1989008651A1 (en) 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
WO1989008652A1 (en) 1988-03-08 1989-09-21 Pfizer Inc. Thiazolidinedione derivatives as hypoglycemic agents
EP0454501B1 (en) * 1990-04-27 2001-09-05 Sankyo Company Limited Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides
FI930772L (fi) 1990-08-23 1993-02-22 Pfizer Hydroxiureaderivat som saenker glugosnivao i blodet
WO1993013095A1 (en) 1991-12-20 1993-07-08 The Upjohn Company A reduction method for substituted 5-methylene-thiazolidinediones
FR2688220A1 (fr) 1992-03-06 1993-09-10 Adir Nouveaux derives de thiazolidine-2,4-dione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4317320A1 (de) * 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
WO1995018125A1 (en) 1993-12-27 1995-07-06 Japan Tobacco Inc. Isoxazolidinedione derivative and use thereof

Also Published As

Publication number Publication date
PL335903A1 (en) 2000-05-22
CN1250448A (zh) 2000-04-12
CA2285208C (en) 2003-07-08
CA2285208A1 (en) 1998-10-01
ZA982326B (en) 1999-09-20
PT970077E (pt) 2003-08-29
US6441185B2 (en) 2002-08-27
US6258832B1 (en) 2001-07-10
KR100340353B1 (ko) 2002-06-12
NO994505D0 (no) 1999-09-17
JP2004067697A (ja) 2004-03-04
RS49771B (sr) 2008-06-05
TR199902197T2 (xx) 1999-12-21
YU46699A (sh) 2002-06-19
AU726048B2 (en) 2000-10-26
JP3484200B2 (ja) 2004-01-06
NZ337608A (en) 2001-05-25
HUP0001551A3 (en) 2000-12-28
IL131772A0 (en) 2001-03-19
RU2181724C2 (ru) 2002-04-27
AU7036198A (en) 1998-10-20
PL192201B1 (pl) 2006-09-29
DE19711616A1 (de) 1998-09-24
HK1025965A1 (en) 2000-12-01
AR012124A1 (es) 2000-09-27
CN1105718C (zh) 2003-04-16
IL131772A (en) 2002-09-12
US20010008902A1 (en) 2001-07-19
NO313292B1 (no) 2002-09-09
JP2000512312A (ja) 2000-09-19
WO1998042704A1 (de) 1998-10-01
ATE240324T1 (de) 2003-05-15
KR20000076344A (ko) 2000-12-26
HUP0001551A2 (hu) 2000-11-28
EP0970077A1 (de) 2000-01-12
DE59808365D1 (de) 2003-06-18
BR9808029A (pt) 2000-03-08
NO994505L (no) 1999-11-17
EP0970077B1 (de) 2003-05-14
ES2198053T3 (es) 2004-01-16
TW487707B (en) 2002-05-21

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