DK0977848T3 - Human theta-underenhed af GABA-A-receptoren - Google Patents

Human theta-underenhed af GABA-A-receptoren

Info

Publication number
DK0977848T3
DK0977848T3 DK98917470T DK98917470T DK0977848T3 DK 0977848 T3 DK0977848 T3 DK 0977848T3 DK 98917470 T DK98917470 T DK 98917470T DK 98917470 T DK98917470 T DK 98917470T DK 0977848 T3 DK0977848 T3 DK 0977848T3
Authority
DK
Denmark
Prior art keywords
receptor
gaba
theta subunit
cell line
human
Prior art date
Application number
DK98917470T
Other languages
Danish (da)
English (en)
Inventor
Paul John Whiting
Timothy Peter Bonnert
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of DK0977848T3 publication Critical patent/DK0977848T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrotherapy Devices (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Radio Relay Systems (AREA)
  • Saccharide Compounds (AREA)
DK98917470T 1997-04-25 1998-04-24 Human theta-underenhed af GABA-A-receptoren DK0977848T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9708479.2A GB9708479D0 (en) 1997-04-25 1997-04-25 Nucleic acids

Publications (1)

Publication Number Publication Date
DK0977848T3 true DK0977848T3 (da) 2005-11-14

Family

ID=10811405

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98917470T DK0977848T3 (da) 1997-04-25 1998-04-24 Human theta-underenhed af GABA-A-receptoren

Country Status (11)

Country Link
US (1) US6555341B1 (fr)
EP (1) EP0977848B1 (fr)
JP (1) JP2002501382A (fr)
AT (1) ATE300612T1 (fr)
AU (1) AU7069498A (fr)
CA (1) CA2287782A1 (fr)
DE (1) DE69830989T2 (fr)
DK (1) DK0977848T3 (fr)
ES (1) ES2244057T3 (fr)
GB (1) GB9708479D0 (fr)
WO (1) WO1998049293A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7151601A (en) * 2000-06-27 2002-01-08 Lexicon Genetics Inc Novel human gaba receptors and polynucleotides encoding the same
EP1500703A3 (fr) * 2000-06-27 2005-02-16 Lexicon Genetics Incorporated Récepteurs gaba humains et polynucléotides les codant
WO2007002359A2 (fr) * 2005-06-24 2007-01-04 The Regents Of The University Of California Methodes d'identification d'agents modulateurs du recepteur gaba contenant la sous-unite delta
US20100311610A1 (en) * 2008-02-01 2010-12-09 Chromocell Corporation CELL LINES AND METHODS FOR MAKING AND USING THEM (As Amended)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69333923T2 (de) 1992-12-10 2006-08-03 Merck Sharp & Dohme Ltd., Hoddesdon Stabil transfizierte Zelllinien welche Gaba-A- Rezeptoren mit der Untereinheitenzusammensetzung alpha-3, beta-3 und gamma-2 exprimieren
GB9408064D0 (en) 1994-04-22 1994-06-15 Merck Sharp & Dohme Nucleic acids

Also Published As

Publication number Publication date
EP0977848A1 (fr) 2000-02-09
DE69830989D1 (de) 2005-09-01
CA2287782A1 (fr) 1998-11-05
WO1998049293A1 (fr) 1998-11-05
JP2002501382A (ja) 2002-01-15
ES2244057T3 (es) 2005-12-01
DE69830989T2 (de) 2006-04-20
US6555341B1 (en) 2003-04-29
ATE300612T1 (de) 2005-08-15
GB9708479D0 (en) 1997-06-18
AU7069498A (en) 1998-11-24
EP0977848B1 (fr) 2005-07-27

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