DK0980387T3 - PRRSV-antigene sites, der identificerer peptidsekvenser af PRRS-virus, til anvendelse i vacciner eller diagnostiske assays - Google Patents

PRRSV-antigene sites, der identificerer peptidsekvenser af PRRS-virus, til anvendelse i vacciner eller diagnostiske assays

Info

Publication number
DK0980387T3
DK0980387T3 DK98921916T DK98921916T DK0980387T3 DK 0980387 T3 DK0980387 T3 DK 0980387T3 DK 98921916 T DK98921916 T DK 98921916T DK 98921916 T DK98921916 T DK 98921916T DK 0980387 T3 DK0980387 T3 DK 0980387T3
Authority
DK
Denmark
Prior art keywords
vaccines
peptide sequences
diagnostic assays
prrs virus
antigenic sites
Prior art date
Application number
DK98921916T
Other languages
Danish (da)
English (en)
Inventor
Nieuwstadt Antonie Paul Van
Jan Langeveld
Janneke Meulenberg
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Application granted granted Critical
Publication of DK0980387T3 publication Critical patent/DK0980387T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK98921916T 1997-05-06 1998-05-05 PRRSV-antigene sites, der identificerer peptidsekvenser af PRRS-virus, til anvendelse i vacciner eller diagnostiske assays DK0980387T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97201343 1997-05-06
PCT/NL1998/000251 WO1998050426A1 (en) 1997-05-06 1998-05-05 Prrsv antigenic sites identifying peptide sequences of prrs virus for use in vaccines or diagnostic assays

Publications (1)

Publication Number Publication Date
DK0980387T3 true DK0980387T3 (da) 2007-10-22

Family

ID=8228298

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98921916T DK0980387T3 (da) 1997-05-06 1998-05-05 PRRSV-antigene sites, der identificerer peptidsekvenser af PRRS-virus, til anvendelse i vacciner eller diagnostiske assays

Country Status (21)

Country Link
US (1) US6495138B1 (de)
EP (2) EP0980387B1 (de)
JP (1) JP2000512313A (de)
KR (1) KR100388257B1 (de)
CN (1) CN1259141B (de)
AT (1) ATE365746T1 (de)
AU (1) AU754938B2 (de)
BR (1) BR9809221A (de)
CA (2) CA2703181C (de)
CZ (1) CZ297371B6 (de)
DE (1) DE69837992T2 (de)
DK (1) DK0980387T3 (de)
ES (1) ES2289781T3 (de)
HU (1) HU228704B1 (de)
ID (1) ID23399A (de)
PL (1) PL197057B1 (de)
PT (1) PT980387E (de)
RU (1) RU2220978C2 (de)
SK (1) SK286063B6 (de)
UA (1) UA73915C2 (de)
WO (1) WO1998050426A1 (de)

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US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6773908B1 (en) 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
EP0839912A1 (de) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
DE19850718C1 (de) * 1998-11-03 2000-05-18 Hildt Eberhardt Zellpermeabilität-vermittelndes Polypeptid
EP1157121B1 (de) * 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Prrsv replikon
DK2251419T3 (da) 1999-04-22 2012-07-02 Us Agriculture Porcint reproduktions- og respirations-syndrom-vaccine baseret på isolat JA-142
RU2003129068A (ru) * 2001-03-09 2005-04-10 Бёрингер Ингельхайм Ветмедика Гмбх (De) Штаммы вируса репродуктивного и респираторного синдрома свиней (prrs) с ослабленной жизнеспособностью
US7335361B2 (en) * 2003-06-09 2008-02-26 Animal Technology Institute Taiwan Fusion antigen used as vaccine
AU2005265142A1 (en) 2004-06-18 2006-01-26 Regents Of The University Of Minnesota Identifying virally infected and vaccinated organisms
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
KR101329696B1 (ko) * 2005-02-25 2013-11-25 아이덱스 래보러토리즈, 인코포레이티드 돼지 생식기 호흡기 증후군 바이러스에 대한 항체를 검출하기 위한 펩티드
PL2369001T3 (pl) 2005-06-24 2017-06-30 Regents Of The University Of Minnesota Wirusy PRRS, ich klony zakaźne, mutanty i sposoby stosowania
CA2630648C (en) 2005-11-29 2016-01-19 Iowa State University Research Foundation, Inc. Identification of protective antigenic determinants of porcine reproductive and respiratory syndrome virus (prrsv) and uses thereof
WO2007065151A2 (en) 2005-12-02 2007-06-07 Iowa State University Research Foundation, Inc. Differential immunoassay for prrs vaccine antibody
EP2328612A4 (de) * 2008-08-25 2012-11-14 Boehringer Ingelheim Vetmed Impfstoff gegen hoch pathogenen seuchenhaften spätabort der schweine (prrs)
KR101101386B1 (ko) * 2008-12-04 2012-01-02 주식회사 바이오리쏘스 북미형 ｐｒｒｓｖ에 특이적인 면역원성 펩티드 및 그의 용도
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
EP2576789A4 (de) * 2010-06-02 2014-01-22 Virginia Tech Intell Prop Neue modifizierte lebendimpfstoffe (mlv) und durch dna-shuffling gegen das prrs-virus gewonnene untereinheits-impfstoffe
CN101885759B (zh) * 2010-06-25 2013-01-09 国家兽用生物制品工程技术研究中心 一种特异性结合猪繁殖与呼吸综合症病毒的多肽及其筛选方法和应用
PH12013501708B1 (en) 2011-02-17 2018-08-03 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of prrsv
HRP20151031T1 (hr) 2011-02-17 2015-11-06 Boehringer Ingelheim Vetmedica Gmbh Novi europski soj prrsv
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
CN103648527B (zh) * 2011-12-30 2017-03-22 美国联合生物医学公司 有效控制猪繁殖与呼吸综合征(prrs)的基于合成肽的标记疫苗和诊断系统
KR101430223B1 (ko) * 2012-10-09 2014-09-25 전북대학교산학협력단 면역유도능이 증가된 돼지생식기호흡기증후군 바이러스
CN103421817B (zh) * 2012-10-15 2016-01-13 华中农业大学 人工合成的猪繁殖与呼吸综合征病毒多表位基因及应用
CA2892948C (en) 2012-12-07 2022-09-20 The Board Of Trustees Of The University Of Illinois Porcine reproductive and respiratory syndrome virus compositions and uses thereof
CN103059142B (zh) * 2012-12-17 2015-02-25 重庆市畜牧科学院 猪圆环病毒的抗原和猪繁殖与呼吸综合征病毒的抗原的重组蛋白及其制备方法与应用
CN105073130A (zh) 2013-03-15 2015-11-18 勃林格殷格翰动物保健公司 猪生殖与呼吸综合征病毒、组合物、疫苗及使用方法
EP2804000A1 (de) * 2013-05-15 2014-11-19 Prionics AG Verfahren zur Erkennung und Klassifizierung von PRRSV-Infektionen bei Schweineherden und diagnostische Antigenzusammensetzungen für derartige Verfahren
ES2729838T3 (es) 2013-12-20 2019-11-06 Boehringer Ingelheim Vetmedica Gmbh Variante del virus del PRRS, clon de ADNc del virus del PRRS europeo y usos del mismo
CN107635579A (zh) 2014-03-21 2018-01-26 纽泰克温图斯公司 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法
DK3313864T3 (da) 2015-06-23 2021-11-01 Boehringer Ingelheim Animal Health Usa Inc Rekombinante virusvektorer indeholdende prrsv minor protein og fremgangsmåder til fremstilling og anvendelse deraf
CN106442968B (zh) * 2016-09-21 2018-03-06 福建省农业科学院畜牧兽医研究所 猪繁殖与呼吸综合征血清学鉴别诊断试剂盒
CN109022613A (zh) * 2018-04-24 2018-12-18 上海申亚动物保健品阜阳有限公司 一种检测猪繁殖与呼吸综合征病毒的试剂盒及检测方法
KR102091279B1 (ko) * 2018-08-07 2020-03-20 대한민국 돼지 생식기 및 호흡기 증후군 바이러스 진단용 재조합 항원 단백질 및 이의 용도
KR102138287B1 (ko) * 2018-08-07 2020-07-29 대한민국 돼지 생식기 및 호흡기 증후군 바이러스 진단용 유전형별 재조합 항원 단백질 및 이의 용도
CN110894243B (zh) * 2019-12-16 2021-07-13 中国农业大学 一种猪蓝耳病毒嵌合抗原以及检测猪蓝耳病毒抗体的胶体金免疫层析试纸条
CN112458115B (zh) * 2020-10-21 2022-06-07 天津农学院 一种基因构建重组质粒pEGFP-GRE-GP5gB及应用

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Also Published As

Publication number Publication date
CZ9903932A3 (cs) 2000-10-11
ID23399A (id) 2000-04-20
CZ297371B6 (cs) 2006-11-15
WO1998050426A1 (en) 1998-11-12
UA73915C2 (uk) 2005-10-17
PL197057B1 (pl) 2008-02-29
HUP0002176A2 (hu) 2000-11-28
DE69837992T2 (de) 2008-03-20
CN1259141B (zh) 2013-03-27
PT980387E (pt) 2007-07-31
KR100388257B1 (ko) 2003-06-19
SK152699A3 (en) 2000-08-14
CA2289980C (en) 2010-07-20
HUP0002176A3 (en) 2001-09-28
SK286063B6 (sk) 2008-02-05
KR20010012337A (ko) 2001-02-15
CA2703181C (en) 2016-06-28
EP1882696A2 (de) 2008-01-30
EP0980387A1 (de) 2000-02-23
HU228704B1 (en) 2013-05-28
AU754938B2 (en) 2002-11-28
ATE365746T1 (de) 2007-07-15
AU7457198A (en) 1998-11-27
EP1882696A3 (de) 2008-03-05
DE69837992D1 (de) 2007-08-09
RU2220978C2 (ru) 2004-01-10
JP2000512313A (ja) 2000-09-19
CN1259141A (zh) 2000-07-05
PL336714A1 (en) 2000-07-03
US6495138B1 (en) 2002-12-17
EP0980387B1 (de) 2007-06-27
CA2703181A1 (en) 1998-11-12
ES2289781T3 (es) 2008-02-01
CA2289980A1 (en) 1998-11-12
BR9809221A (pt) 2000-07-04

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