ATE365746T1 - Prrsv-antigene, die auf peptidsequenzen des prrs- virus basieren, für die verwendung als impfstoff und für diagnostische tests - Google Patents

Prrsv-antigene, die auf peptidsequenzen des prrs- virus basieren, für die verwendung als impfstoff und für diagnostische tests

Info

Publication number
ATE365746T1
ATE365746T1 AT98921916T AT98921916T ATE365746T1 AT E365746 T1 ATE365746 T1 AT E365746T1 AT 98921916 T AT98921916 T AT 98921916T AT 98921916 T AT98921916 T AT 98921916T AT E365746 T1 ATE365746 T1 AT E365746T1
Authority
AT
Austria
Prior art keywords
vaccines
peptide sequences
diagnostic tests
prrs
prrsv
Prior art date
Application number
AT98921916T
Other languages
English (en)
Inventor
Nieuwstadt Antonie Van
Jan Langeveld
Janneke Meulenberg
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Application granted granted Critical
Publication of ATE365746T1 publication Critical patent/ATE365746T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT98921916T 1997-05-06 1998-05-05 Prrsv-antigene, die auf peptidsequenzen des prrs- virus basieren, für die verwendung als impfstoff und für diagnostische tests ATE365746T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97201343 1997-05-06

Publications (1)

Publication Number Publication Date
ATE365746T1 true ATE365746T1 (de) 2007-07-15

Family

ID=8228298

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98921916T ATE365746T1 (de) 1997-05-06 1998-05-05 Prrsv-antigene, die auf peptidsequenzen des prrs- virus basieren, für die verwendung als impfstoff und für diagnostische tests

Country Status (21)

Country Link
US (1) US6495138B1 (de)
EP (2) EP0980387B1 (de)
JP (1) JP2000512313A (de)
KR (1) KR100388257B1 (de)
CN (1) CN1259141B (de)
AT (1) ATE365746T1 (de)
AU (1) AU754938B2 (de)
BR (1) BR9809221A (de)
CA (2) CA2703181C (de)
CZ (1) CZ297371B6 (de)
DE (1) DE69837992T2 (de)
DK (1) DK0980387T3 (de)
ES (1) ES2289781T3 (de)
HU (1) HU228704B1 (de)
ID (1) ID23399A (de)
PL (1) PL197057B1 (de)
PT (1) PT980387E (de)
RU (1) RU2220978C2 (de)
SK (1) SK286063B6 (de)
UA (1) UA73915C2 (de)
WO (1) WO1998050426A1 (de)

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US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6773908B1 (en) 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP0839912A1 (de) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren
DE19850718C1 (de) * 1998-11-03 2000-05-18 Hildt Eberhardt Zellpermeabilität-vermittelndes Polypeptid
EP1157121B1 (de) * 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Prrsv replikon
ES2388909T3 (es) 1999-04-22 2012-10-19 The United States Of America, As Represented Bythe Secretary Of Agriculture Vacuna contra el virus del síndrome respiratorio y reproductivo porcino basada en aislado JA-142 aislada
WO2002072802A2 (en) * 2001-03-09 2002-09-19 Boehringer Ingelheim Vetmedica Gmbh Live attenuated strains of prrs virus
US7335361B2 (en) * 2003-06-09 2008-02-26 Animal Technology Institute Taiwan Fusion antigen used as vaccine
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CN106075422B (zh) 2005-11-29 2021-05-28 衣阿华州立大学研究基金公司 猪繁殖与呼吸综合征病毒(prrsv)的保护性抗原决定子的鉴定及其用途
US20100227339A1 (en) * 2005-12-02 2010-09-09 Iowa State University Research Foundation, Inc. Differential immunoassay for prrs vaccine antibody
KR101653177B1 (ko) * 2008-08-25 2016-09-01 베링거잉겔하임베트메디카인코퍼레이티드 고병원성 돼지 생식기 및 호흡기 증후군(ｈｐ ｐｒｒｓ)에 대한 백신
KR101101386B1 (ko) * 2008-12-04 2012-01-02 주식회사 바이오리쏘스 북미형 ｐｒｒｓｖ에 특이적인 면역원성 펩티드 및 그의 용도
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
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CN101885759B (zh) * 2010-06-25 2013-01-09 国家兽用生物制品工程技术研究中心 一种特异性结合猪繁殖与呼吸综合症病毒的多肽及其筛选方法和应用
SG192821A1 (en) 2011-02-17 2013-09-30 Boehringer Ingelheim Vetmed Commercial scale process for production of prrsv
EP2675475B1 (de) 2011-02-17 2015-07-01 Boehringer Ingelheim Vetmedica GmbH Neuer europäischer prrsv-stamm
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
EP2737059A1 (de) 2011-07-29 2014-06-04 Boehringer Ingelheim Vetmedica GmbH Neuartiges prrs-virus zur induktion von interferon des typs i in empfindlichen zellen
BR112014015898B1 (pt) 2011-12-30 2022-04-12 United Biomedical, Inc Composições de vacina para a síndrome reprodutiva e respiratória do suíno (prrs) compreendendo antígeno de peptídeo e uso das referidas composições para preparação de uma vacina para proteção de leitões contra infecção por prrs
KR101430223B1 (ko) * 2012-10-09 2014-09-25 전북대학교산학협력단 면역유도능이 증가된 돼지생식기호흡기증후군 바이러스
CN103421817B (zh) * 2012-10-15 2016-01-13 华中农业大学 人工合成的猪繁殖与呼吸综合征病毒多表位基因及应用
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CN103059142B (zh) * 2012-12-17 2015-02-25 重庆市畜牧科学院 猪圆环病毒的抗原和猪繁殖与呼吸综合征病毒的抗原的重组蛋白及其制备方法与应用
US9579373B2 (en) 2013-03-15 2017-02-28 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
EP2804000A1 (de) * 2013-05-15 2014-11-19 Prionics AG Verfahren zur Erkennung und Klassifizierung von PRRSV-Infektionen bei Schweineherden und diagnostische Antigenzusammensetzungen für derartige Verfahren
DK3591042T5 (da) 2013-12-20 2024-09-02 Boehringer Ingelheim Vetmedica Gmbh PRRS-virusvariant, cDNA-klon af europæisk PRRS-virus samt anvendelser deraf
HK1247128A1 (zh) 2014-03-21 2018-09-21 纽泰克温图斯公司 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法
US9981033B2 (en) 2015-06-23 2018-05-29 Merial Inc. PRRSV minor protein-containing recombinant viral vectors and methods of making and use thereof
CN106442968B (zh) * 2016-09-21 2018-03-06 福建省农业科学院畜牧兽医研究所 猪繁殖与呼吸综合征血清学鉴别诊断试剂盒
CN109022613A (zh) * 2018-04-24 2018-12-18 上海申亚动物保健品阜阳有限公司 一种检测猪繁殖与呼吸综合征病毒的试剂盒及检测方法
KR102091279B1 (ko) * 2018-08-07 2020-03-20 대한민국 돼지 생식기 및 호흡기 증후군 바이러스 진단용 재조합 항원 단백질 및 이의 용도
KR102138287B1 (ko) * 2018-08-07 2020-07-29 대한민국 돼지 생식기 및 호흡기 증후군 바이러스 진단용 유전형별 재조합 항원 단백질 및 이의 용도
CN110894243B (zh) * 2019-12-16 2021-07-13 中国农业大学 一种猪蓝耳病毒嵌合抗原以及检测猪蓝耳病毒抗体的胶体金免疫层析试纸条
CN112458115B (zh) * 2020-10-21 2022-06-07 天津农学院 一种基因构建重组质粒pEGFP-GRE-GP5gB及应用

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Also Published As

Publication number Publication date
PL336714A1 (en) 2000-07-03
HU228704B1 (en) 2013-05-28
WO1998050426A1 (en) 1998-11-12
CN1259141B (zh) 2013-03-27
CA2703181C (en) 2016-06-28
KR100388257B1 (ko) 2003-06-19
EP0980387B1 (de) 2007-06-27
US6495138B1 (en) 2002-12-17
CA2703181A1 (en) 1998-11-12
DK0980387T3 (da) 2007-10-22
KR20010012337A (ko) 2001-02-15
PL197057B1 (pl) 2008-02-29
SK286063B6 (sk) 2008-02-05
JP2000512313A (ja) 2000-09-19
CN1259141A (zh) 2000-07-05
AU7457198A (en) 1998-11-27
BR9809221A (pt) 2000-07-04
PT980387E (pt) 2007-07-31
CZ297371B6 (cs) 2006-11-15
CA2289980C (en) 2010-07-20
EP0980387A1 (de) 2000-02-23
CZ9903932A3 (cs) 2000-10-11
UA73915C2 (uk) 2005-10-17
CA2289980A1 (en) 1998-11-12
EP1882696A2 (de) 2008-01-30
SK152699A3 (en) 2000-08-14
HUP0002176A3 (en) 2001-09-28
EP1882696A3 (de) 2008-03-05
RU2220978C2 (ru) 2004-01-10
DE69837992D1 (de) 2007-08-09
ES2289781T3 (es) 2008-02-01
HUP0002176A2 (hu) 2000-11-28
ID23399A (id) 2000-04-20
AU754938B2 (en) 2002-11-28
DE69837992T2 (de) 2008-03-20

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