DK100588A - 3-amino-dihydro-(1)-benzopyraner og -benzothiopyraner - Google Patents

3-amino-dihydro-(1)-benzopyraner og -benzothiopyraner

Info

Publication number: DK100588A
Authority: DK; Denmark
Prior art keywords: compounds; lower alkyl; denotes; aryl; sulphur
Prior art date: 1987-02-27

Application number

DK100588A

Other languages

Danish (da)

English (en)

Other versions

DK100588D0 (da

Inventor

Alan J Hutchison

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-27

Filing date

1988-02-26

Publication date

1988-08-28

1988-02-26 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1988-02-26 Publication of DK100588D0 publication Critical patent/DK100588D0/da

1988-08-28 Publication of DK100588A publication Critical patent/DK100588A/da

Links

125000000217 alkyl group Chemical group 0.000 abstract 6
150000001875 compounds Chemical class 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000003545 alkoxy group Chemical group 0.000 abstract 4
150000002431 hydrogen Chemical class 0.000 abstract 4
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 3
239000005864 Sulphur Substances 0.000 abstract 3
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 3
229910052760 oxygen Inorganic materials 0.000 abstract 3
239000001301 oxygen Substances 0.000 abstract 3
125000004423 acyloxy group Chemical group 0.000 abstract 2
125000004104 aryloxy group Chemical group 0.000 abstract 2
210000003169 central nervous system Anatomy 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
102000005962 receptors Human genes 0.000 abstract 1
108020003175 receptors Proteins 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229940121356 serotonin receptor antagonist Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pyrane Compounds (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Cephalosporin Compounds (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK100588A 1987-02-27 1988-02-26 3-amino-dihydro-(1)-benzopyraner og -benzothiopyraner DK100588A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/020,054 US4801605A (en)	1986-08-29	1987-02-27	3-amino-dihydro-[1]-benzopyrans and benzothiopyrans

Publications (2)

Publication Number	Publication Date
DK100588D0 DK100588D0 (da)	1988-02-26
DK100588A true DK100588A (da)	1988-08-28

Family

ID=21796497

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK100588A DK100588A (da)	1987-02-27	1988-02-26	3-amino-dihydro-(1)-benzopyraner og -benzothiopyraner

Country Status (20)

Country	Link
US (1)	US4801605A (fr)
EP (1)	EP0280269B1 (fr)
JP (1)	JPS63277671A (fr)
KR (1)	KR880009953A (fr)
AT (1)	ATE72563T1 (fr)
AU (1)	AU612625B2 (fr)
DD (1)	DD273256A5 (fr)
DE (1)	DE3868329D1 (fr)
DK (1)	DK100588A (fr)
ES (1)	ES2038707T3 (fr)
FI (1)	FI880866A7 (fr)
GR (1)	GR3003800T3 (fr)
HU (1)	HU201920B (fr)
IL (1)	IL85494A0 (fr)
NO (1)	NO880843L (fr)
NZ (1)	NZ223647A (fr)
PH (1)	PH23479A (fr)
PT (1)	PT86830B (fr)
YU (1)	YU36688A (fr)
ZA (1)	ZA881375B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0325964A1 (fr) *	1988-01-15	1989-08-02	Abbott Laboratories	Composés aminométhyliques de chromane et thiochromane
DK0389425T3 (da) *	1989-03-22	1995-05-22	Ciba Geigy Ag	Benzothiopyranylaminer
US5306830A (en) *	1989-04-27	1994-04-26	The Upjohn Company	Substituted 3-amino chromans
DE69005625T2 (de) *	1989-04-27	1994-05-11	Upjohn Co	Substituierte 3-amino-chromane.
US5155130A (en) *	1989-08-11	1992-10-13	Ciba-Geigy Corporation	Certain benzopyran and benzothiopyran derivatives
SE8904361D0 (sv) *	1989-12-22	1989-12-22	Astra Ab	New chroman and thiochroman derivatives
US5616610A (en) *	1989-12-22	1997-04-01	Astra Aktiebolag	(R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) *	1989-12-22	1995-05-30	Aktiebolaget Astra	Chroman derivatives
DK0471515T3 (da) *	1990-08-15	1997-07-21	Lilly Co Eli	Ringsubstituerede 2-amino-1,2,3,4-tetrahydronphtalener, 3-aminochromaner og 3-aminothiochromaner
US5348973A (en) *	1990-10-09	1994-09-20	Rhone-Poulenc Chimie	Resolution of hydroxychroman-2-carboxylic acid esters by enantiomeric hydrolysis
NZ241495A (en) *	1991-02-08	1994-10-26	Lilly Co Eli	2-amino-1,2,3,4-tetrahydronaphthalene and 3-aminochromane derivative, preparation and pharmaceutical compositions thereof
US5120758A (en) *	1991-02-08	1992-06-09	Ciba-Geigy Corporation	Certain benzodioxole, benzodioxane and benzodioxepin derivatives useful as 5-lipoxygenase inhibitors
DE4128690A1 (de) *	1991-08-29	1993-03-04	Boehringer Mannheim Gmbh	Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
HRP920935A2 (en) *	1991-10-08	1995-08-31	Astra Ab	New therapeutically active compound
US5478857A (en) *	1993-12-23	1995-12-26	Eli Lilly And Company	Use of PLA2 inhibitors as treatment for alzheimer's disease
IT1271009B (it) *	1994-09-13	1997-05-26	Zambon Spa	Derivati del benzopirano e del benzotiopirano attivi sul sistema cardiovascolare
SE9701438D0 (sv) *	1997-04-17	1997-04-17	Astra Ab	A new process
GB9801812D0 (en) *	1998-01-29	1998-03-25	Zeneca Ltd	Chemical compounds
GB0426061D0 (en) *	2004-11-26	2004-12-29	Pfizer Ltd	Chroman compounds
WO2009082268A2 (fr)	2007-12-21	2009-07-02	Alla Chem, Llc	Ligands dalpha-adrénorécepteurs, de récepteurs de dopamine, de l'histamine, d'imidazoline et de sérotonine ainsi que leurs procédés d'utilisation

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3142682A (en) *	1961-11-21	1964-07-28	Ciba Geigy Corp	Tertiary amino derivatives of chromans and homo-chromans
GB1086101A (en) *	1965-01-19	1967-10-04	Ciba Ltd	New chromans and process for preparing same
US3629289A (en) *	1969-04-24	1971-12-21	Parke Davis & Co	Chromanamines
US3607886A (en) *	1969-04-24	1971-09-21	Parke Davis & Co	Chromanamines
JPS561305B2 (fr) *	1972-12-18	1981-01-13
US4062870A (en) *	1974-05-31	1977-12-13	Beecham Group Limited	Chroman derivatives
US4013771A (en) *	1975-12-15	1977-03-22	Warner-Lambert Company	Substituted 2-aminothiochromones
LU79077A1 (de) *	1978-02-16	1979-09-06	Ciba Geigy Ag	Verfahren zur herstellung neuer benzothiopyranderivate
US4203895A (en) *	1978-04-14	1980-05-20	Warner-Lambert Company	Process for the preparation of cis-(±)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine and intermediates produced thereby
US4232953A (en) *	1979-06-27	1980-11-11	Alvarez Sabater Fernando	Gravity-feed rotary tray slide projector
IT1226045B (it) *	1981-07-29	1990-12-10	Simes	Derivati tetraidrochinolici
EP0076075B1 (fr) *	1981-09-25	1986-11-20	Beecham Group Plc	Dérivés de benzopyranes pharmacologiquement actifs
FI79535C (fi) *	1982-05-06	1990-01-10	Erba Farmitalia	Foerfarande foer framstaellning av dihydrobensopyrans och dihydrobensotiopyrans substituerade iminoderivat.
US4500545A (en) *	1982-11-16	1985-02-19	Eli Lilly And Company	Hydroxyaminotetralincarboxamides
JPS59110690A (ja) *	1982-12-16	1984-06-26	Dai Ichi Seiyaku Co Ltd	ベンゾピラン誘導体
US4657925A (en) *	1984-08-13	1987-04-14	Nelson Research & Development Co.	Method and compositions for reducing the intraocular pressure of mammals
ATE64735T1 (de) *	1984-05-10	1991-07-15	Ciba Geigy Ag	Benzo-(pyrano und thiopyrano)-pyridine.
US4736031A (en) *	1985-06-10	1988-04-05	Takeda Chemical Industries, Ltd.	2-(piperazinylalkyl)-1-benzothiepin, 1-benzoxepin, and 1,5-benzodioxepin derivatives
PH22522A (en) *	1985-09-03	1988-10-17	Ciba Geigy Ag	3-amino-dihydro-1-benzopyrans and benzothiopyrans, their pharmaceutical compositions and method of using said compounds
SE8605504D0 (sv) *	1986-12-19	1986-12-19	Astra Laekemedel Ab	Novel chroman derivatives

1987
- 1987-02-27 US US07/020,054 patent/US4801605A/en not_active Expired - Fee Related
1988
- 1988-02-22 IL IL85494A patent/IL85494A0/xx unknown
- 1988-02-24 ES ES198888102716T patent/ES2038707T3/es not_active Expired - Lifetime
- 1988-02-24 EP EP88102716A patent/EP0280269B1/fr not_active Expired - Lifetime
- 1988-02-24 FI FI880866A patent/FI880866A7/fi not_active Application Discontinuation
- 1988-02-24 AT AT88102716T patent/ATE72563T1/de not_active IP Right Cessation
- 1988-02-24 DE DE8888102716T patent/DE3868329D1/de not_active Expired - Lifetime
- 1988-02-25 PT PT86830A patent/PT86830B/pt not_active IP Right Cessation
- 1988-02-25 DD DD88313194A patent/DD273256A5/de unknown
- 1988-02-25 NZ NZ223647A patent/NZ223647A/en unknown
- 1988-02-25 YU YU00366/88A patent/YU36688A/xx unknown
- 1988-02-26 HU HU88928A patent/HU201920B/hu not_active IP Right Cessation
- 1988-02-26 NO NO880843A patent/NO880843L/no unknown
- 1988-02-26 AU AU12347/88A patent/AU612625B2/en not_active Ceased
- 1988-02-26 ZA ZA881375A patent/ZA881375B/xx unknown
- 1988-02-26 KR KR1019880001965A patent/KR880009953A/ko not_active Withdrawn
- 1988-02-26 PH PH36562A patent/PH23479A/en unknown
- 1988-02-26 DK DK100588A patent/DK100588A/da unknown
- 1988-02-27 JP JP63043340A patent/JPS63277671A/ja active Pending
1992
- 1992-02-13 GR GR910402100T patent/GR3003800T3/el unknown

Also Published As

Publication number	Publication date
JPS63277671A (ja)	1988-11-15
DD273256A5 (de)	1989-11-08
ZA881375B (en)	1988-08-29
NO880843D0 (no)	1988-02-26
ES2038707T3 (es)	1993-08-01
GR3003800T3 (fr)	1993-03-16
KR880009953A (ko)	1988-10-06
ATE72563T1 (de)	1992-02-15
EP0280269A1 (fr)	1988-08-31
AU1234788A (en)	1988-09-01
EP0280269B1 (fr)	1992-02-12
US4801605A (en)	1989-01-31
NO880843L (no)	1988-08-29
DK100588D0 (da)	1988-02-26
PT86830A (pt)	1988-03-01
NZ223647A (en)	1991-06-25
FI880866A0 (fi)	1988-02-24
PH23479A (en)	1989-08-07
AU612625B2 (en)	1991-07-18
PT86830B (pt)	1992-05-29
IL85494A0 (en)	1988-07-31
HU201920B (en)	1991-01-28
DE3868329D1 (de)	1992-03-26
FI880866A7 (fi)	1988-08-28
YU36688A (en)	1990-04-30

Publication	Publication Date	Title
FI880866A0 (fi)	1988-02-24	3-amino-dihydro-(1)-bensopyraner och -bensotiopyraner.
NO863507D0 (no)	1986-09-02	3-amino-dihydro-(1)-benxopyraner og-benzotiopyraner.
AR011229A1 (es)	2000-08-02	Compuestos derivados de adenosina antagonistas en el receptor ai adenosina, procesos para su preparacion, composiciones farmaceuticas que los contieneny su uso en medicina.
AR247389A1 (es)	1994-12-29	Derivados de 2,4-diamino-5-ciano-pirimidinas, excluidos sus usos terapeuticos, procedimiento para su preparacion, intermediarios y composiciones que las contienen como antiparasitarios
BE1003230A3 (fr)	1992-02-04	Nouveaux derives du benzotriazole, leur preparation et leur utilisation comme absorbants u.v.
GB8518658D0 (en)	1985-08-29	Medicaments
ES2071479T3 (es)	1995-06-16	Derivados de indano.
ES2063381T3 (es)	1995-01-01	Antagonistas de los receptores muscarinicos.
DK583184A (da)	1985-06-08	Substituerede o-acyl-glycosylamider, fremgangsmaader til deres fremstilling samt deres anvendelse
ZA919954B (en)	1992-10-28	Phenylalkylaminoalkyl compounds and methods for the preparation thereof and medicaments containing these compounds
DK29587A (da)	1987-07-22	Pyrrolooe1,2-aaaoe4,1aabenzoxazepiner og salte deraf samt deres fremstilling og anvendelse