DK1024829T3 - Tolerogene fragmenter af naturlige allergener - Google Patents

Tolerogene fragmenter af naturlige allergener

Info

Publication number: DK1024829T3
Authority: DK; Denmark
Prior art keywords: fragments; relates; allergens; natural; epitopes
Prior art date: 1997-10-30

Application number

DK97954496T

Other languages

English (en)

Inventor

Romano Maria Leticia Gonzales

Camara Maria Teresa Gallego

Lubertus Berrens

Original Assignee

Lab Leti S L

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-30

Filing date

1997-10-30

Publication date

2009-02-09

1997-10-30 Application filed by Lab Leti S L filed Critical Lab Leti S L

2009-02-09 Application granted granted Critical

2009-02-09 Publication of DK1024829T3 publication Critical patent/DK1024829T3/da

Links

239000013566 allergen Substances 0.000 title abstract 3
239000012634 fragment Substances 0.000 title abstract 3
230000003614 tolerogenic effect Effects 0.000 title 1
230000002009 allergenic effect Effects 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
241000282414 Homo sapiens Species 0.000 abstract 1
230000017274 T cell anergy Effects 0.000 abstract 1
210000001744 T-lymphocyte Anatomy 0.000 abstract 1
230000000172 allergic effect Effects 0.000 abstract 1
208000010668 atopic eczema Diseases 0.000 abstract 1
210000003719 b-lymphocyte Anatomy 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
238000003776 cleavage reaction Methods 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1
239000000284 extract Substances 0.000 abstract 1
230000001900 immune effect Effects 0.000 abstract 1
238000009169 immunotherapy Methods 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
229940127557 pharmaceutical product Drugs 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
230000007017 scission Effects 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43527—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from ticks
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Immunology (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Veterinary Medicine (AREA)
Mycology (AREA)
Insects & Arthropods (AREA)
Microbiology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Analytical Chemistry (AREA)
Tropical Medicine & Parasitology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Zoology (AREA)
Water Supply & Treatment (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Toxicology (AREA)
Pulmonology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Chemical Or Physical Treatment Of Fibers (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK97954496T 1997-10-30 1997-10-30 Tolerogene fragmenter af naturlige allergener DK1024829T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/NL1997/000598 WO1999022762A1 (en)	1997-10-30	1997-10-30	Tolerogenic fragments of natural allergens

Publications (1)

Publication Number	Publication Date
DK1024829T3 true DK1024829T3 (da)	2009-02-09

Family

ID=19866218

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97954496T DK1024829T3 (da)	1997-10-30	1997-10-30	Tolerogene fragmenter af naturlige allergener

Country Status (16)

Country	Link
US (2)	US6350590B1 (da)
EP (2)	EP2042192A3 (da)
JP (1)	JP3790099B2 (da)
AT (1)	ATE417626T1 (da)
AU (1)	AU729589C (da)
BR (1)	BR9714899A (da)
CA (1)	CA2307655C (da)
CZ (1)	CZ302352B6 (da)
DE (1)	DE69739174D1 (da)
DK (1)	DK1024829T3 (da)
ES (1)	ES2319341T3 (da)
HU (1)	HUP0004831A3 (da)
IL (1)	IL135881A0 (da)
PL (1)	PL187544B1 (da)
PT (1)	PT1024829E (da)
WO (1)	WO1999022762A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3790099B2 (ja) *	1997-10-30	2006-06-28	シー・ビー・エフ・レティ・エス・エー	天然アレルゲンの寛容原性断片
JPWO2003020306A1 (ja) *	2001-08-29	2004-12-16	伊東　恭悟	脱感作剤
EP1872792A1 (en) *	2006-06-29	2008-01-02	Biotech Tools S.A.	A method for the production of hydrolyzed allergen
WO2009083589A1 (en) *	2008-01-02	2009-07-09	Biotech Tools S.A.	Pharmaceutical formulation for allergen preparation
KR20140041505A (ko)	2011-04-29	2014-04-04	셀렉타 바이오사이언시즈, 인크.	조절 b 세포 유도를 위한 관용원성 합성 나노운반체
HUE052599T2 (hu)	2013-05-03	2021-05-28	Selecta Biosciences Inc	CD4+ szabályozó T-sejtek fokozására szolgáló eljárások és készítmények
AU2015311704B2 (en)	2014-09-07	2021-12-09	Selecta Biosciences, Inc.	Methods and compositions for attenuating gene editing anti-viral transfer vector immune responses
PL3522921T3 (pl)	2016-10-05	2021-10-18	Asit Biotech S.A.	Zapobieganie alergii
WO2018169811A1 (en)	2017-03-11	2018-09-20	Selecta Biosciences, Inc.	Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant
CN114207440A (zh)	2019-06-04	2022-03-18	西莱克塔生物科技公司	聚乙二醇化尿酸酶的制剂和剂量

Family Cites Families (16)

* Cited by examiner, † Cited by third party
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US150389A (en)		1874-05-05		Improvement in combined paper-clips and letter-folders
GB1282163A (en)	1969-08-06	1972-07-19	Beecham Group Ltd	Modified allergens and a process for their preparation
GB1492973A (en)	1974-02-16	1977-11-23	Beecham Group Ltd	Process for preparing injectable compositions
GB1578348A (en)	1976-08-17	1980-11-05	Pharmacia Ab	Products and a method for the therapeutic suppression of reaginic antibodies responsible for common allergic
US4338297A (en)	1980-02-19	1982-07-06	Michael Jacob G	Polypeptide active pollen immunosuppressant fraction
EP0038154B1 (en)	1980-04-15	1983-09-21	Beecham Group Plc	Allergens modified with polysarcosines
JPS58115120A (ja)	1981-12-28	1983-07-08	Nippon Oil Co Ltd	ピツチ系炭素繊維の製造方法
ES2013359A6 (es)	1988-11-04	1990-05-01	Corporacion Biolog Farmaceutic	Procedimiento para la fabricacion de alergenos inmunogenicos polimerizados.
NL8900652A (nl)	1989-03-16	1990-10-16	Leti Lab	Primair-toxische stoffen of allergenen, isoleerbaar uit plantaardig materiaal, alsmede werkwijzen ter bereiding ervan en de toepassing ervan.
US5792506A (en) *	1991-10-12	1998-08-11	The Regents Of The University Of California	Neutralization of food allergens by thioredoxin
AU675629B2 (en) *	1992-09-21	1997-02-13	Laboratorios Leti S.A.	A process for the purification of aqueous extracts containing allergenically active proteins, extracts obtainable according to this process as well as their use
WO1994006821A1 (en) *	1992-09-21	1994-03-31	Laboratorios Leti S.A.	A process for the purification of aqueous extracts containing allergenically active proteins, extracts obtainable according to this process as well as their use
FI972443L (fi) *	1994-12-07	1997-06-09	Novo Nordisk As	Polypeptidi, jonka allergeenisuus on vähentynyt
CZ283615B6 (cs) *	1996-05-31	1998-05-13	Bioveta, A.S.	Způsob výroby vakcín proti dermatofytózám zvířat a dermatofytických alergenů
JP3790099B2 (ja) *	1997-10-30	2006-06-28	シー・ビー・エフ・レティ・エス・エー	天然アレルゲンの寛容原性断片
WO2004031961A1 (en)	2002-09-30	2004-04-15	Insignia Solutions Plc	Efficient system and method for updating a memory device

1997
- 1997-10-30 JP JP2000518693A patent/JP3790099B2/ja not_active Expired - Fee Related
- 1997-10-30 HU HU0004831A patent/HUP0004831A3/hu unknown
- 1997-10-30 PT PT97954496T patent/PT1024829E/pt unknown
- 1997-10-30 PL PL97340293A patent/PL187544B1/pl not_active IP Right Cessation
- 1997-10-30 DK DK97954496T patent/DK1024829T3/da active
- 1997-10-30 WO PCT/NL1997/000598 patent/WO1999022762A1/en not_active Ceased
- 1997-10-30 BR BR9714899-7A patent/BR9714899A/pt not_active Application Discontinuation
- 1997-10-30 US US09/530,277 patent/US6350590B1/en not_active Expired - Lifetime
- 1997-10-30 CZ CZ20001529A patent/CZ302352B6/cs not_active IP Right Cessation
- 1997-10-30 CA CA002307655A patent/CA2307655C/en not_active Expired - Fee Related
- 1997-10-30 EP EP08171363A patent/EP2042192A3/en not_active Withdrawn
- 1997-10-30 EP EP97954496A patent/EP1024829B1/en not_active Expired - Lifetime
- 1997-10-30 DE DE69739174T patent/DE69739174D1/de not_active Expired - Lifetime
- 1997-10-30 AT AT97954496T patent/ATE417626T1/de not_active IP Right Cessation
- 1997-10-30 ES ES97954496T patent/ES2319341T3/es not_active Expired - Lifetime
- 1997-10-30 IL IL13588197A patent/IL135881A0/xx unknown
- 1997-10-30 AU AU58833/98A patent/AU729589C/en not_active Ceased
2001
- 2001-12-04 US US10/000,453 patent/US6660495B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES2319341T3 (es)	2009-05-06
CZ20001529A3 (cs)	2000-10-11
EP1024829A1 (en)	2000-08-09
AU729589B2 (en)	2001-02-08
CZ302352B6 (cs)	2011-03-30
BR9714899A (pt)	2000-08-22
HUP0004831A3 (en)	2001-09-28
DE69739174D1 (de)	2009-01-29
CA2307655C (en)	2005-05-24
US6660495B2 (en)	2003-12-09
US6350590B1 (en)	2002-02-26
EP1024829B1 (en)	2008-12-17
PL187544B1 (pl)	2004-07-30
AU5883398A (en)	1999-05-24
IL135881A0 (en)	2001-05-20
HUP0004831A2 (hu)	2001-05-28
ATE417626T1 (de)	2009-01-15
US20020086348A1 (en)	2002-07-04
EP2042192A2 (en)	2009-04-01
JP3790099B2 (ja)	2006-06-28
CA2307655A1 (en)	1999-05-14
EP2042192A3 (en)	2009-05-27
AU729589C (en)	2001-08-30
JP2001521907A (ja)	2001-11-13
WO1999022762A1 (en)	1999-05-14
PT1024829E (pt)	2009-03-18
PL340293A1 (en)	2001-01-29

Publication	Publication Date	Title
DK1024829T3 (da)	2009-02-09	Tolerogene fragmenter af naturlige allergener
DE69730038D1 (de)	2004-09-02	Lösliche monovalente und multivalente mhc klasse ii fusionsproteine und deren verwendungen
HUP0003280A1 (hu)	2001-01-29	Apolipoprotein A-1 agonista peptidek, ezeket hatóanyagként tartalmazó gyógyászati készítmények és alkalmazásuk
TR200100936T2 (tr)	2001-08-21	Terapötik aşılama
EP1724282A3 (en)	2007-08-01	Method for the production of non-immunogenic proteins
NZ331651A (en)	2000-01-28	BSW17 peptide immunogens for vaccination against and treatment of allergy
ATE318899T1 (de)	2006-03-15	Fusionsproteine, die stressproteine beinhalten, zum hervorrufen einer immunantwort
HK1049279A1 (zh)	2003-05-09	预防及治疗阿尔茨海默病(早老性痴呆)及淀粉样蛋白有关的病之疫苗
ATE408690T1 (de)	2008-10-15	Mutiertes rekombinantes allergen
MA24638A1 (fr)	1999-04-01	Vaccin
GB2255093A (en)	1992-10-28	Hiv-1 core protein fragments
FI962619L (fi)	1996-06-25	Autoantigeenistä johdettuja uusia peptidejä autoimmuunitautien immunoterapiassa käyttöä varten
NO20001421D0 (no)	2000-03-17	T-cellevaksinasjon for behandling av multippel sklerose
PL335981A1 (en)	2000-06-05	Modified recombinative alegenes of gramminae pollen for use in specific immunotherapy, method of obtaining them and their application
ATE290081T1 (de)	2005-03-15	Parietaria judaica ns-ltp-antigenvarianten, entsprechende pharmazeutische zusammensetzungen und ihre verwendung
DK1019085T3 (da)	2009-06-22	Ikke-anafylaktiske former for allergener og deres anvendelse
WO1994010194A3 (de)	1994-09-01	MOLEKÜLFRAGMENTE (PEPTIDE) DER HAUPTALLERGENE DER POLLEN VON BÄUMEN DER ORDNUNG $i(FAGALES)
ATE385809T1 (de)	2008-03-15	Saponin-zusammensetzungen und deren verwendung
EP1131338A4 (en)	2002-08-28	PROCESS FOR PRODUCING HIGHLY PURIFIED INVASINATED PROTEIN AND USE OF SUCH PROTEIN
WO2002063012A3 (en)	2003-03-13	Ragweed allergens
AU2001295558A1 (en)	2002-03-26	Variants of phleum pratense allergenic proteins
AU2002212230A1 (en)	2002-03-26	Variants of the major allergen par j 2 of parietaria judaica
SE9903950D0 (sv)	1999-10-29	Non-anaphylactic forms of grass pollen allergen and their use
ES2125201A1 (es)	1999-02-16	Adn recombinante que codifica para epitopos del alergeno mayor de olea europaea ole e 1 util para el diagnostico y tratamiento de alergias.
IT1290764B1 (it)	1998-12-10	Pentapeptide per la preparazione di composizioni dermo- farmaceutiche e cosmetiche per il trattamento di lesioni od affezioni cutanee