DK1036202T3 - Fremgangsmåde til identifikation af nucleinsyrer ved matriksassisteret laserdesorptions/ionisationsmassespektrometri - Google Patents

Fremgangsmåde til identifikation af nucleinsyrer ved matriksassisteret laserdesorptions/ionisationsmassespektrometri

Info

Publication number
DK1036202T3
DK1036202T3 DK98966608T DK98966608T DK1036202T3 DK 1036202 T3 DK1036202 T3 DK 1036202T3 DK 98966608 T DK98966608 T DK 98966608T DK 98966608 T DK98966608 T DK 98966608T DK 1036202 T3 DK1036202 T3 DK 1036202T3
Authority
DK
Denmark
Prior art keywords
nucleic acids
mass spectrometry
laser desorption
assisted laser
ionization mass
Prior art date
Application number
DK98966608T
Other languages
Danish (da)
English (en)
Inventor
Kurt Berlin
Hans Lehrach
Ivo Glynne Gut
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Application granted granted Critical
Publication of DK1036202T3 publication Critical patent/DK1036202T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • H01J49/0418—Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK98966608T 1997-12-05 1998-12-04 Fremgangsmåde til identifikation af nucleinsyrer ved matriksassisteret laserdesorptions/ionisationsmassespektrometri DK1036202T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97121471 1997-12-05
PCT/EP1998/007911 WO1999029898A2 (fr) 1997-12-05 1998-12-04 Procede d'identification d'acides nucleiques par spectrometrie de masse par ionisation/desorption laser assistee par matrice

Publications (1)

Publication Number Publication Date
DK1036202T3 true DK1036202T3 (da) 2002-08-12

Family

ID=8227757

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98966608T DK1036202T3 (da) 1997-12-05 1998-12-04 Fremgangsmåde til identifikation af nucleinsyrer ved matriksassisteret laserdesorptions/ionisationsmassespektrometri

Country Status (8)

Country Link
EP (1) EP1036202B1 (fr)
JP (1) JP2001526381A (fr)
AT (1) ATE217028T1 (fr)
CA (1) CA2312052A1 (fr)
DE (1) DE59804008D1 (fr)
DK (1) DK1036202T3 (fr)
ES (1) ES2173670T3 (fr)
WO (1) WO1999029898A2 (fr)

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EP1370685A2 (fr) * 2000-04-06 2003-12-17 Epigenomics AG Diagnostic de maladies associees a la reparation de l'adn
DE10027120A1 (de) 2000-05-23 2001-12-06 Epigenomics Ag Probenträger für Massenspektrometer
AU2001276371A1 (en) * 2000-06-30 2002-01-14 Epigenomics Ag Method and nucleic acids for analysing the methylation of genes implicated pharmacogenomics
DE10054974A1 (de) * 2000-11-06 2002-06-06 Epigenomics Ag Diagnose von mit Cdk4 assoziierten Krankheiten
DE10061338A1 (de) * 2000-12-06 2002-06-20 Epigenomics Ag Diagnose von mit Angiogenese assoziierten Krankheiten
EP1215199A1 (fr) * 2000-12-08 2002-06-19 Sony International (Europe) GmbH Linker molécules pour la métallisation sélective des acides nucléiques et de leurs utilisations
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US20040121309A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
WO2004060278A2 (fr) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Procedes d'identification rapide de pathogenes chez l'homme et les betes
JP2002372517A (ja) * 2001-05-31 2002-12-26 Inst Of Physical & Chemical Res 質量分析法によるタンパク質の構造解析方法
US8073627B2 (en) 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
US20050164193A1 (en) * 2002-03-25 2005-07-28 Epigenomics Ag Method for the analysis of methylation patterns within nucleic acids by means of mass spectrometry
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US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US20120122102A1 (en) 2003-09-11 2012-05-17 Rangarajan Sampath Compositions for use in identification of bacteria
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8163895B2 (en) 2003-12-05 2012-04-24 Ibis Biosciences, Inc. Compositions for use in identification of orthopoxviruses
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
JP4810533B2 (ja) 2004-05-24 2011-11-09 アイビス バイオサイエンシズ インコーポレイティッド ディジタルスレショルド化による選択的イオン濾過作用を用いた質量分光測定法
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
US20060205040A1 (en) 2005-03-03 2006-09-14 Rangarajan Sampath Compositions for use in identification of adventitious viruses
US8026084B2 (en) 2005-07-21 2011-09-27 Ibis Biosciences, Inc. Methods for rapid identification and quantitation of nucleic acid variants
EP1775348A1 (fr) * 2005-10-17 2007-04-18 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Procédé d'analyse d'acides nucléiques par spectrométrie de masse
US8088582B2 (en) 2006-04-06 2012-01-03 Ibis Biosciences, Inc. Compositions for the use in identification of fungi
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JP5680304B2 (ja) 2007-02-23 2015-03-04 アイビス バイオサイエンシズ インコーポレイティッド 迅速な法医学的dna分析法
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EP2349549B1 (fr) 2008-09-16 2012-07-18 Ibis Biosciences, Inc. Cartouches de mélange, postes de mélange et kits, et système associé
EP2344893B1 (fr) 2008-09-16 2014-10-15 Ibis Biosciences, Inc. Systèmes et procédés de manipulation de microplaques
EP2347254A2 (fr) 2008-09-16 2011-07-27 Ibis Biosciences, Inc. Unités de traitement d'échantillons, systèmes et procédés associés
EP2396803A4 (fr) 2009-02-12 2016-10-26 Ibis Biosciences Inc Ensembles sonde d'ionisation
WO2010104798A1 (fr) 2009-03-08 2010-09-16 Ibis Biosciences, Inc. Procédés de détection d'un bioagent
US9393564B2 (en) 2009-03-30 2016-07-19 Ibis Biosciences, Inc. Bioagent detection systems, devices, and methods
US8950604B2 (en) 2009-07-17 2015-02-10 Ibis Biosciences, Inc. Lift and mount apparatus
WO2011008972A1 (fr) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Systèmes pour l'identification d'un bioagent
US9416409B2 (en) 2009-07-31 2016-08-16 Ibis Biosciences, Inc. Capture primers and capture sequence linked solid supports for molecular diagnostic tests
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NL2022038B1 (en) * 2018-11-21 2020-06-05 Biosparq B V Method for analysing an analyte sample and matrix material therefore

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EP1400599B1 (fr) * 1997-01-15 2007-10-03 Xzillion GmbH & CO.KG Sondes d'hybridation couplées à des marqueurs de masse

Also Published As

Publication number Publication date
JP2001526381A (ja) 2001-12-18
WO1999029898A2 (fr) 1999-06-17
CA2312052A1 (fr) 1999-06-17
DE59804008D1 (de) 2002-06-06
ATE217028T1 (de) 2002-05-15
WO1999029898A3 (fr) 1999-10-28
ES2173670T3 (es) 2002-10-16
EP1036202A2 (fr) 2000-09-20
EP1036202B1 (fr) 2002-05-02

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