DK1037627T3 - Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske... - Google Patents

Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske...

Info

Publication number: DK1037627T3
Authority: DK; Denmark
Prior art keywords: dihydrodibenz; oxepin; propylidene; allergic; dimethylamino
Prior art date: 1998-07-14

Application number

DK99928600T

Other languages

English (en)

Inventor

John M Yanni

Daniel A Gamache

Lori K Weimer

Original Assignee

Alcon Lab Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-14

Filing date

1999-06-15

Publication date

2001-10-01

1999-06-15 Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc

2001-10-01 Application granted granted Critical

2001-10-01 Publication of DK1037627T3 publication Critical patent/DK1037627T3/da

Links

JBIMVDZLSHOPLA-UHFFFAOYSA-N 2-[11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid Chemical compound C1OC2=CC=C(CC(O)=O)C=C2C(=CCCN(C)C)C2=CC=CC=C21 JBIMVDZLSHOPLA-UHFFFAOYSA-N 0.000 title 1
230000000172 allergic effect Effects 0.000 title 1
208000010668 atopic eczema Diseases 0.000 title 1
239000003814 drug Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrane Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK99928600T 1998-07-14 1999-06-15 Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske... DK1037627T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US9276298P	1998-07-14	1998-07-14
PCT/US1999/013275 WO2000003705A1 (en)	1998-07-14	1999-06-15	Use of 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid for the manufacture of a medicament for treating non-allergic ophthalmic inflammatory disorders and for the prevention of ocular neovascularization

Publications (1)

Publication Number	Publication Date
DK1037627T3 true DK1037627T3 (da)	2001-10-01

Family

ID=22235027

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99928600T DK1037627T3 (da)	1998-07-14	1999-06-15	Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske...

Country Status (17)

Country	Link
EP (1)	EP1037627B1 (da)
JP (1)	JP2002520355A (da)
KR (1)	KR100598723B1 (da)
CN (1)	CN1114401C (da)
AR (1)	AR019916A1 (da)
AT (1)	ATE203668T1 (da)
AU (1)	AU742237B2 (da)
BR (1)	BR9906772A (da)
CA (1)	CA2306393C (da)
DE (1)	DE69900207T2 (da)
DK (1)	DK1037627T3 (da)
ES (1)	ES2159209T3 (da)
GR (1)	GR3036422T3 (da)
PT (1)	PT1037627E (da)
TW (1)	TW561046B (da)
WO (1)	WO2000003705A1 (da)
ZA (1)	ZA200001593B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1187617E (pt)	1999-06-18	2004-06-30	Alcon Mfg Ltd	Metodo para seleccionar a concentracao de um farmaco antipatico anti-histaminico pela determinacao da taxa de actividade superficial do farmaco
US20020077358A1 (en) *	2000-10-23	2002-06-20	Alcon Universal Ltd.	Use of hydroperoxyeicosatetraenoic acid derivatives following refractive surgery
ATE353667T1 (de)	2001-05-21	2007-03-15	Alcon Inc	Verwendung von proteasom-inhibitoren zur behandlung des trockenen auges
US6872382B1 (en)	2001-05-21	2005-03-29	Alcon, Inc.	Use of selective PDE IV inhibitors to treat dry eye disorders
US7112588B2 (en)	2001-05-21	2006-09-26	Alcon, Inc.	Use of proteasome inhibitors to treat dry eye disorders
BR0209965A (pt)	2001-05-21	2004-04-06	Alcon Inc	Uso de inibidores de nf-kappab para tratar distúrbios do olho seco
US6645994B1 (en)	2001-06-01	2003-11-11	Alcon, Inc.	Method of treating dry eye disorders
TWI231759B (en)	2001-06-27	2005-05-01	Alcon Inc	Olopatadine formulations for topical administration
US7977376B2 (en)	2001-06-27	2011-07-12	Novartis Ag	Olopatadine formulations for topical nasal administration
US6825232B2 (en)	2002-06-14	2004-11-30	Alcon, Inc.	Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders
CN103143022A (zh)	2002-07-30	2013-06-12	奥默罗斯公司	眼科冲洗液及方法
BR0314603A (pt) *	2002-09-20	2005-07-26	Alcon Inc	Uso de inibidores da sìntese de citoquina para o tratamento de distúrbios de olhos secos
US7235556B2 (en)	2003-04-16	2007-06-26	Alcon, Inc.	Methods of treating dry eye disorders
US20050232972A1 (en)	2004-04-15	2005-10-20	Steven Odrich	Drug delivery via punctal plug
US7923471B2 (en)	2004-05-14	2011-04-12	Alcon, Inc.	Method of treating dry eye disorders and uveitis
EP1765454B1 (en)	2004-07-02	2016-04-13	Mati Therapeutics Inc.	Treatment medium delivery device for the eye
US7223737B1 (en)	2004-08-13	2007-05-29	Alcon, Inc.	Method of treating dry eye disorders using glycosides
US8168655B2 (en) *	2005-05-17	2012-05-01	Sarcode Bioscience Inc.	Compositions and methods for treatment of eye disorders
US7745461B1 (en)	2006-02-27	2010-06-29	Alcon Research, Ltd.	Method of treating dry eye disorders
AR059927A1 (es)	2006-03-17	2008-05-07	Johnson & Johnson Vision Care	Metodos para la estabilizacion de composiciones inestables a la oxidacion y composiciones oftalmicas estabilizadas
EP2004172B1 (en)	2006-03-31	2019-03-13	Mati Therapeutics Inc.	Drug delivery structures and compositions for nasolacrimal system
US9011361B2 (en)	2007-09-07	2015-04-21	Mati Therapeutics Inc.	Lacrimal implant detection
US8207226B1 (en)	2008-06-03	2012-06-26	Alcon Research, Ltd.	Use of FAAH antagonists for treating dry eye and ocular pain
WO2011057183A1 (en)	2009-11-06	2011-05-12	Alcon Research, Ltd.	Nutritional supplements for relief of dry eye
AU2013201465B2 (en)	2012-10-24	2016-03-03	Rayner Intraocular Lenses Limited	Stable preservative-free mydriatic and anti-inflammatory solutions for injection
TWI705812B (zh)	2014-12-01	2020-10-01	奥默羅斯公司	用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液
CN109311976A (zh)	2016-06-20	2019-02-05	诺华股份有限公司	使用TNFα拮抗剂治疗干眼症的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6310784A (ja) *	1986-03-03	1988-01-18	Kyowa Hakko Kogyo Co Ltd	抗アレルギー剤
JPH02138215A (ja) *	1988-08-05	1990-05-28	Dai Ichi Seiyaku Co Ltd	抗アレルギー・抗炎症剤
IE920499A1 (en) *	1991-02-21	1992-08-26	Merck Frosst Canada Inc	Quinoline-containing ketoacids as leukotriene antagonists
IL102414A (en) *	1991-07-25	1996-08-04	Univ Louisville Res Found	Medicinal preparations for the treatment of ocular inflammation, containing rapamycin
JP3453152B2 (ja) *	1992-04-06	2003-10-06	格冨山	抗炎症点眼剤
FR2701948B1 (fr) *	1993-02-22	1996-07-26	Exsymol Sa	Produit de couplage de l'histamine ou l'histamine méthyl-substituée et d'un acide aminé, procédé de préparation et applications thérapeutiques, cosmétologiques et agroalimentaires.
CA2159091C (en) *	1993-03-26	2006-12-19	Richard J. Sharpe	Topical and systemic application of buspirone or derivatives thereof for treatment of pathological conditions associated with immune responses
FR2711990B1 (fr) *	1993-11-05	1995-12-08	Exsymol Sa	Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires.
JP2852607B2 (ja) *	1994-06-10	1999-02-03	雪印乳業株式会社	ドライアイ治療剤
US5641805A (en) *	1995-06-06	1997-06-24	Alcon Laboratories, Inc.	Topical ophthalmic formulations for treating allergic eye diseases
JPH1067684A (ja) *	1996-06-17	1998-03-10	Mitsubishi Chem Corp	涙液分泌促進剤
CA2272073A1 (en) *	1996-11-19	1998-05-28	The Schepens Eye Research Institute, Inc.	Local use of il-1ra in corneal transplant rejection or disorders of the eye

1999
- 1999-06-15 DK DK99928600T patent/DK1037627T3/da active
- 1999-06-15 DE DE69900207T patent/DE69900207T2/de not_active Expired - Lifetime
- 1999-06-15 CN CN99801501A patent/CN1114401C/zh not_active Expired - Fee Related
- 1999-06-15 WO PCT/US1999/013275 patent/WO2000003705A1/en not_active Ceased
- 1999-06-15 ES ES99928600T patent/ES2159209T3/es not_active Expired - Lifetime
- 1999-06-15 EP EP99928600A patent/EP1037627B1/en not_active Expired - Lifetime
- 1999-06-15 AU AU45634/99A patent/AU742237B2/en not_active Ceased
- 1999-06-15 JP JP2000559840A patent/JP2002520355A/ja not_active Withdrawn
- 1999-06-15 KR KR1020007004037A patent/KR100598723B1/ko not_active Expired - Fee Related
- 1999-06-15 BR BR9906772-2A patent/BR9906772A/pt not_active Application Discontinuation
- 1999-06-15 CA CA002306393A patent/CA2306393C/en not_active Expired - Fee Related
- 1999-06-15 PT PT81300632T patent/PT1037627E/pt unknown
- 1999-06-15 AT AT99928600T patent/ATE203668T1/de active
- 1999-06-25 TW TW088110742A patent/TW561046B/zh not_active IP Right Cessation
- 1999-07-13 AR ARP990103415A patent/AR019916A1/es unknown
2000
- 2000-03-29 ZA ZA200001593A patent/ZA200001593B/xx unknown
2001
- 2001-08-20 GR GR20010401273T patent/GR3036422T3/el unknown

Also Published As

Publication number	Publication date
GR3036422T3 (en)	2001-11-30
EP1037627A1 (en)	2000-09-27
JP2002520355A (ja)	2002-07-09
KR100598723B1 (ko)	2006-07-11
ES2159209T3 (es)	2001-09-16
AU4563499A (en)	2000-02-07
TW561046B (en)	2003-11-11
CN1114401C (zh)	2003-07-16
CA2306393C (en)	2008-12-23
ZA200001593B (en)	2000-10-25
HK1030362A1 (en)	2001-05-04
AU742237B2 (en)	2001-12-20
CA2306393A1 (en)	2000-01-27
AR019916A1 (es)	2002-03-27
DE69900207T2 (de)	2001-11-22
EP1037627B1 (en)	2001-08-01
DE69900207D1 (de)	2001-09-06
PT1037627E (pt)	2001-11-30
WO2000003705A1 (en)	2000-01-27
BR9906772A (pt)	2000-09-26
ATE203668T1 (de)	2001-08-15
CN1275078A (zh)	2000-11-29
KR20010024508A (ko)	2001-03-26

Publication	Publication Date	Title
DE69900207D1 (de)	2001-09-06	Verwendung von 11-(3-dimethylaminopropyliden)-6,11-dihydrodibenz[b,e]oxepin-2-essigsäure und deren pharmazeutisch annehmbaren salzen zur herstellung eines medikaments zur behandlung nicht-allergisch-bedingten augenentzündungen und zur prevention der okularen neovaskularisation
BR0001826B1 (pt)	2008-11-18	fralda descartÁvel.
MA25413A1 (fr)	2002-04-01	Fabrication de micromousse therapeutique.
DE60029883D1 (de)	2006-09-21	Medizinischer Vernebler
NO20022970L (no)	2002-06-20	Hydrogel-drevet medikamentdoseringsform
NO20021400L (no)	2002-05-06	Terapeutiske kinazolinderivater
NO20013560D0 (no)	2001-07-18	Polymorfer av telmisartan, fremgangsmåter for fremstilling derav og anvendelse derav for fremstilling av et medikament
FI20000863A0 (fi)	2000-04-11	Uusi hoitomenetelmä
DE50111900D1 (de)	2007-03-08	Medizinisches implantat
AU2001276860A1 (en)	2002-01-30	Medicaments for chemotherapeutic treatment of disease
HUP0301333A3 (en)	2005-06-28	Pharmaceutical superdisintegrant, process for its preparation and its use
NO20005179D0 (no)	2000-10-13	Medikament behandling
NO994165D0 (no)	1999-08-27	Anvendelse av deskarboetoksyloratadin for fremstilling av et medikament for behandling av urininkontinens, reisesyke og svimmelhet
BR0000706B1 (pt)	2009-01-13	fralda descartÁvel.
EE200100422A (et)	2002-12-16	Epotilooni derivaadid, nende valmistamismeetod jafarmatseutiline kasutamine
IT1318514B1 (it)	2003-08-27	Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
EE200100553A (et)	2003-02-17	Saredutandi ja selle farmatseutiliselt vastuvõetavate soolade kasutamine meeleoluhäirete, kohanemishäirete või segatüüpi ärev-depressiivsete häirete raviks või vältimiseks kasulike ravimite valmistamiseks
NO20010219L (no)	2001-03-15	Polycykliske tiazolidin-2-ylidenaminer, fremgangsmÕte for deres fremstilling og deres anvendelse som legemiddel
WO2001060343A3 (de)	2002-05-30	Verwendung von 2-methyl-thiazolidin-2,4-dicarbonsäure und/oder ihrer physiologisch verträglichen salze zur herstellung eines medikaments zur behandlung von krebserkrankungen
IL150290A (en)	2010-12-30	Use of mirtazapine for preparation of a medicament for the treatment of sleep disorders
ITMI20001848A0 (it)	2000-08-08	Faramaci per l'incontinenza.
BR0004412B1 (pt)	2008-11-18	fralda descartÁvel.
AU2562501A (en)	2002-05-15	Use of melagatran for manufacture of a medicament for the treatment of ischemic disorders
WO2002083083A3 (en)	2003-11-06	Pharmaceutically active compounds and methods of use
NO20032411L (no)	2003-07-17	Anvendelse av substituerte 6-dimetylaminometyl-1-fenyl- cykloheksan-forbindelser for behandling av urininkontinens