DK105290D0 - Terapeutisk polyamin-amider - Google Patents

Terapeutisk polyamin-amider

Info

Publication number
DK105290D0
DK105290D0 DK105290A DK105290A DK105290D0 DK 105290 D0 DK105290 D0 DK 105290D0 DK 105290 A DK105290 A DK 105290A DK 105290 A DK105290 A DK 105290A DK 105290 D0 DK105290 D0 DK 105290D0
Authority
DK
Denmark
Prior art keywords
alkyl
different
cycloalkyl
optionally
substituents
Prior art date
Application number
DK105290A
Other languages
English (en)
Other versions
DK105290A (da
Inventor
Peter Norman Russell Usherwood
Barrie Walsham Bycroft
Ian Stuart Blagbrough
Alan John Mather
Original Assignee
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Dev filed Critical Nat Res Dev
Publication of DK105290A publication Critical patent/DK105290A/da
Publication of DK105290D0 publication Critical patent/DK105290D0/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/50—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
DK105290A 1988-08-30 1990-04-27 Terapeutisk polyamin-amider DK105290D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888820442A GB8820442D0 (en) 1988-08-30 1988-08-30 Therapeutic polyamine amides
PCT/GB1989/001004 WO1990002114A1 (en) 1988-08-30 1989-08-30 Therapeutic polyamine-amides

Publications (2)

Publication Number Publication Date
DK105290A DK105290A (da) 1990-04-27
DK105290D0 true DK105290D0 (da) 1990-04-27

Family

ID=10642872

Family Applications (1)

Application Number Title Priority Date Filing Date
DK105290A DK105290D0 (da) 1988-08-30 1990-04-27 Terapeutisk polyamin-amider

Country Status (9)

Country Link
US (1) US5218000A (da)
EP (1) EP0361687B1 (da)
JP (1) JPH03501022A (da)
AT (1) ATE96421T1 (da)
AU (1) AU629856B2 (da)
DE (1) DE68910259T2 (da)
DK (1) DK105290D0 (da)
GB (2) GB8820442D0 (da)
WO (1) WO1990002114A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001824A (en) * 1988-02-08 1999-12-14 The Trustees Of Columbia University Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same
US5770625A (en) * 1988-02-08 1998-06-23 The Trustees Of Columbia University In The City Of New York Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same
DD298412A5 (de) * 1989-04-28 1992-02-20 ������@���Kk�� Verfahren zur herstellung von polypeptiden, die geeignet sind als antagonisten exzitatorischer aminosaeure-neurotransmitter und/oder blocker der calciumkanaele
US5059438A (en) * 1990-02-05 1991-10-22 Enzytech, Inc. Compositions and methods for inhibiting browning in foods using resorcinol derivatives
US5269987A (en) * 1992-12-22 1993-12-14 Reedy Michael E Process for producing alkenyl aromatic foams using a combination of atmospheric and organic gases and foams produced thereby
US5998452A (en) * 1993-06-23 1999-12-07 Chugai Seiyaku Kabushiki Kaisha Benzene derivatives, compositions and methods for treating ischemic diseases
KR100262419B1 (ko) * 1993-06-23 2000-09-01 나가야마 오사무 허혈성 질환에 유용한 벤젠 유도체
AU5468299A (en) * 1998-08-06 2000-02-28 Cees Bastiaansen Melt-processible poly(tetrafluoroethylene)
ES2161594B1 (es) * 1998-12-17 2003-04-01 Servier Lab Nuevos derivados de la hidrazida, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
TW541295B (en) * 1999-01-05 2003-07-11 Nippon Zoki Pharmaceutical Co A novel substituted alkylteraamine derivative for use as tachykinin antagonist
US6602515B2 (en) 2001-07-16 2003-08-05 Em Industries Photo stable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom
US6831191B2 (en) 2001-12-20 2004-12-14 Em Industries Photo stable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom
JP2005510524A (ja) 2001-11-16 2005-04-21 アルス・セラピー・デベロツプメント・フアンデーシヨン・インコーポレーテツド ポリアミン経路の調節による神経変性障害の治療
EP1448183A2 (en) * 2001-11-16 2004-08-25 ALS Therapy Development Foundation, Inc. Treatment of neurodegenerative disorders through the modulation of the polyamine pathway
US6699463B2 (en) 2002-04-10 2004-03-02 Em Industries Photostable cationic organic sunscreen compounds with antioxidant properties and compositions obtained therefrom
US6936735B2 (en) * 2002-08-27 2005-08-30 Emd Chemicals, Inc. Photostable cationic organic sunscreen compounds and compositions obtained therefrom
WO2018155260A1 (ja) * 2017-02-23 2018-08-30 株式会社Ihi Ｏｈラジカル検出プローブ、ｏｈラジカル測定装置、および、ｏｈラジカル測定方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB862721A (en) * 1958-06-23 1961-03-15 Miles Lab Dialkylaminoethyl derivatives of salicylamides
GB879957A (en) * 1958-09-22 1961-10-11 Ciba Ltd Improvements relating to the hardening of epoxides
US3272861A (en) * 1961-10-11 1966-09-13 Continental Oil Co Polyalkylene polyamine derivatives of hydroxybenzoic acid
GB1043345A (en) * 1962-02-28 1966-09-21 Minnesota Mining & Mfg Phenolic polyamines
CH448966A (de) * 1965-07-13 1967-09-15 Bayer Ag Verfahren zur Verbesserung der Nassechtheiten von gefärbten textilen Gebilden aus synthetischen Polyamiden
US4172094A (en) * 1976-12-03 1979-10-23 Merck & Co., Inc. Polyamine compounds
US4058624A (en) * 1976-05-14 1977-11-15 Merck & Co., Inc. Broad spectrum antibacterial compositions containing tris (hydroxymethyl)-aminomethane and diphenyl and loweralkyl substituted diphenyl polyamines
GB8419103D0 (en) * 1984-07-26 1984-08-30 Beecham Wuelfing Gmbh & Co Kg Compounds
EP0339927A3 (en) * 1988-04-26 1990-12-05 Takeda Chemical Industries, Ltd. Amide compounds their production and use
US4990511A (en) * 1988-08-03 1991-02-05 Takeda Chemical Industries, Ltd. Amide compounds, their production and use

Also Published As

Publication number Publication date
GB2222590B (en) 1992-07-22
AU4192789A (en) 1990-03-23
WO1990002114A1 (en) 1990-03-08
DK105290A (da) 1990-04-27
GB8919563D0 (en) 1989-10-11
GB2222590A (en) 1990-03-14
AU629856B2 (en) 1992-10-15
GB8820442D0 (en) 1988-09-28
DE68910259D1 (de) 1993-12-02
DE68910259T2 (de) 1994-02-24
JPH03501022A (ja) 1991-03-07
US5218000A (en) 1993-06-08
ATE96421T1 (de) 1993-11-15
EP0361687B1 (en) 1993-10-27
EP0361687A1 (en) 1990-04-04

Similar Documents

Publication Publication Date Title
DK105290D0 (da) Terapeutisk polyamin-amider
NO905572L (no) Fremgangsmaate for fremstilling av peptidforbindelser.
HUP0004529A2 (hu) VLA-4 által mediált leukocita adhéziót gátló szulfonilezett dipeptid-származékok, ezeket tartalmazó gyógyászati készítmények, valamint alkalmazásuk
ATE89559T1 (de) Camptothecin-derivate und verfahren zu ihrer herstellung.
NO179142C (no) 3-benzyliden-1-karbamoyl-2-pyrrolidon-analoger
HUP0004259A2 (hu) VLA-4 által mediált leukocita adhéziót gátló szubsztituált fenilalanin-származékok, ezeket tartalmazó gyógyászati készítmények
ATE117681T1 (de) Chinolinderivate, ihre herstellung und verwendung.
IE872588L (en) Compounds
ES2055077T3 (es) Un procedimiento para preparar derivados de amida de acido carboxilico.
TW249804B (da)
GB1273412A (en) Control of pests with cycloalkane derivatives of nitrated aryl compounds
HUP9900091A2 (hu) Peszticidek
ES347178A1 (es) Procedimiento para la preparacion de nuevas amidas de aci- do.
ATE69225T1 (de) Antiarrhythmische heilmittel.
AU626095B2 (en) Hydroxyalkane carboxylic acid derivatives, their production and use
DK0696585T3 (da) Nyt bisoxadiazolidinderivat
NO941516L (no) 3-kinolylsubstituerte dihydropyridiner, fremgangsmåter for deres fremstilling og deres anvendelse
DE3661198D1 (en) Phosphate ester derivatives, and their use as anti-cancer agents
ATE43140T1 (de) Derivate von enzym-hemmender griseolsaeure und deren verwendung.
KR830010090A (ko) 아닐린 유도체의 제조방법
IE45092L (en) Carbamic acid oxime-esters.
AU597923B2 (en) 5-aminoalkyl-beta-carboline derivatives, their production and their use as drugs
EP0176049A3 (en) Aminoalkylnaphtalene derivatives having pharmacological activities
GR3002560T3 (en) 2-selenomethyl-1, 4-dihydropyridines, a process for the preparation thereof and pharmaceutical compositions containing them
MY104689A (en) Amine salts of 1,4,2-oxazaphospholidine-4-acetic acid, 2-alkoxy-2-oxides.

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment