DK1054892T3 - Azolpeptidmimetiske forbindelser som thrombinreceptorantagonister - Google Patents

Azolpeptidmimetiske forbindelser som thrombinreceptorantagonister

Info

Publication number
DK1054892T3
DK1054892T3 DK99905837T DK99905837T DK1054892T3 DK 1054892 T3 DK1054892 T3 DK 1054892T3 DK 99905837 T DK99905837 T DK 99905837T DK 99905837 T DK99905837 T DK 99905837T DK 1054892 T3 DK1054892 T3 DK 1054892T3
Authority
DK
Denmark
Prior art keywords
azole
receptor antagonists
peptide mimetic
thrombin receptor
mimetic compounds
Prior art date
Application number
DK99905837T
Other languages
English (en)
Inventor
William Hoekstra
Becky L Hulshizer
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK1054892T3 publication Critical patent/DK1054892T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99905837T 1998-02-19 1999-02-08 Azolpeptidmimetiske forbindelser som thrombinreceptorantagonister DK1054892T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7517198P 1998-02-19 1998-02-19
PCT/US1999/002627 WO1999042475A1 (en) 1998-02-19 1999-02-08 Azole peptidomimetics as thrombin receptor antagonists

Publications (1)

Publication Number Publication Date
DK1054892T3 true DK1054892T3 (da) 2003-01-20

Family

ID=22124023

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99905837T DK1054892T3 (da) 1998-02-19 1999-02-08 Azolpeptidmimetiske forbindelser som thrombinreceptorantagonister

Country Status (10)

Country Link
EP (1) EP1054892B1 (da)
JP (1) JP2002504490A (da)
AT (1) ATE223928T1 (da)
AU (1) AU2590799A (da)
CA (1) CA2321104A1 (da)
DE (1) DE69902887T2 (da)
DK (1) DK1054892T3 (da)
ES (1) ES2183515T3 (da)
PT (1) PT1054892E (da)
WO (1) WO1999042475A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU42401A (sh) * 1998-12-14 2003-12-31 Ortho-Mcneil Pharmaceuticals Inc. Supstituisani heterociklični acil-tripeptidi korisni kao modulatori receptora trombina
US6858577B1 (en) 1999-06-29 2005-02-22 Ortho-Mcneil Pharmaceutical, Inc. Indole peptidomimetics as thrombin receptor antagonists
US6630451B1 (en) 1999-06-29 2003-10-07 Orthomcneil Pharmaceutical, Inc. Benzimidazolone peptidometics as thrombin receptor antagonist
WO2001000656A2 (en) 1999-06-29 2001-01-04 Ortho-Mcneil Pharmaceutical, Inc. Novel indazole peptidomimetics as thrombin receptor antagonists
US6365617B1 (en) 1999-06-29 2002-04-02 Ortho-Mcneil Pharmaceutical, Inc. Indole and indazole urea-peptoids as thrombin receptor antagonists
US7622593B2 (en) * 2006-06-27 2009-11-24 The Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
EP2982756A1 (en) * 2014-08-04 2016-02-10 Berlin Cures Holding AG Aptamers for use against autoantibody-associated diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL106197A (en) * 1992-07-30 1999-11-30 Cor Therapeutics Inc Agagonists for the rhombin receptors and pharmaceutical preparations containing them
JPH07285952A (ja) * 1994-04-08 1995-10-31 Fujisawa Pharmaceut Co Ltd 新規複素環誘導体

Also Published As

Publication number Publication date
WO1999042475A1 (en) 1999-08-26
EP1054892B1 (en) 2002-09-11
CA2321104A1 (en) 1999-08-26
DE69902887D1 (de) 2002-10-17
EP1054892A1 (en) 2000-11-29
PT1054892E (pt) 2002-12-31
HK1031388A1 (en) 2001-06-15
AU2590799A (en) 1999-09-06
ES2183515T3 (es) 2003-03-16
JP2002504490A (ja) 2002-02-12
DE69902887T2 (de) 2003-08-07
ATE223928T1 (de) 2002-09-15

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