NO20052884L - Substituerte indolpyridinforbindelser som anti-infeksjonsmidler. - Google Patents

Substituerte indolpyridinforbindelser som anti-infeksjonsmidler.

Info

Publication number
NO20052884L
NO20052884L NO20052884A NO20052884A NO20052884L NO 20052884 L NO20052884 L NO 20052884L NO 20052884 A NO20052884 A NO 20052884A NO 20052884 A NO20052884 A NO 20052884A NO 20052884 L NO20052884 L NO 20052884L
Authority
NO
Norway
Prior art keywords
indolpyridine
substituted
compounds
infective agents
infective
Prior art date
Application number
NO20052884A
Other languages
English (en)
Other versions
NO20052884D0 (no
Inventor
Piet Tom Bert Paul Wigerinck
Dominique Louis Nest Surleraux
Bart Rudolf Romanie Kesteleyn
Dirk Edward Desire Jochmans
Abdellah Tahri
Wim Van De Vreken
Natalie Maria Franc Kindermans
Maxime Francis Jean-Mar Canard
Kurt Hertogs
Eva Bettens
Veronique Corine Paul De Vroey
Jing Wang
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of NO20052884D0 publication Critical patent/NO20052884D0/no
Publication of NO20052884L publication Critical patent/NO20052884L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

2005 -07- 2 9 Sammendrag 0. nr. E40674 Foreliggende oppfinnelse angår nye pyridazinonderivater.
NO20052884A 2002-11-15 2005-06-14 Substituerte indolpyridinforbindelser som anti-infeksjonsmidler. NO20052884L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02079783 2002-11-15
US43495002P 2002-12-20 2002-12-20
PCT/EP2003/050837 WO2004046143A1 (en) 2002-11-15 2003-11-14 Substituted indolepyridinium as anti-infective compounds

Publications (2)

Publication Number Publication Date
NO20052884D0 NO20052884D0 (no) 2005-06-14
NO20052884L true NO20052884L (no) 2005-08-15

Family

ID=32327852

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052884A NO20052884L (no) 2002-11-15 2005-06-14 Substituerte indolpyridinforbindelser som anti-infeksjonsmidler.

Country Status (16)

Country Link
US (2) US7608726B2 (no)
EP (1) EP1594870B1 (no)
JP (1) JP2006508145A (no)
KR (1) KR20050084621A (no)
CN (1) CN100457754C (no)
AP (1) AP1927A (no)
AU (1) AU2003296760B2 (no)
BR (1) BR0316209A (no)
CA (1) CA2506316A1 (no)
EA (1) EA009871B1 (no)
HR (1) HRP20050543A2 (no)
MX (1) MXPA05005146A (no)
NO (1) NO20052884L (no)
NZ (1) NZ540321A (no)
PL (1) PL376683A1 (no)
WO (1) WO2004046143A1 (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
BRPI0511267A (pt) 2004-05-17 2007-11-27 Tibotec Pharm Ltd 1,5-diidropirido[3,2-b]indol-2-onas 4-substituìdas
AP2006003794A0 (en) * 2004-05-17 2006-10-31 Tibotec Pharm Ltd Combinations of substituted 1-phenyl-1,5-dihydropyrido-Ä3,2-bÜindol-2-ones and other HIV inhibitors
US20070238727A1 (en) * 2004-05-17 2007-10-11 Tibotec Bvba 5-Substituted 1-Phenyl-1,5-Dihydro-Pyrido[3,2-B]Indol-2-Ones and Analogs as Anti-Virals
MXPA06013314A (es) * 2004-05-17 2007-02-02 Tibotec Pharm Ltd 1-heterociclil-1,5-dihidro-pirido[3,2-b]indol-2-onas.
WO2005111035A1 (en) * 2004-05-17 2005-11-24 Tibotec Pharmaceuticals Ltd. 6,7,8,9-substituted 1-phenyl-1,5-dihydro-pyrido[3,2-b]indol-2-ones useful as anti-infective pharmaceutical agents
CA2577467C (en) 2004-09-30 2013-05-28 Tibotec Pharmaceuticals Ltd. Hiv inhibiting 5-heterocyclyl pyrimidines
RU2410379C2 (ru) 2004-09-30 2011-01-27 Тиботек Фармасьютикалз Лтд. 5-замещенные пиримидины, ингибирующие вич
AR056918A1 (es) 2005-01-10 2007-11-07 Tibotec Pharm Ltd 2-oxo-3-ciano-1,6a-diaza-tetrahidro-fluorantenos 1,5,6-sustituidos, proceso de preparacion del compuesto y composicion farmaceutica
WO2006082250A1 (en) * 2005-02-04 2006-08-10 Tibotec Pharmaceuticals Ltd. Screening method for competitive hiv rt inhibitors
JP2009525310A (ja) * 2006-02-03 2009-07-09 テイボテク・フアーマシユーチカルズ・リミテツド 突然変異したｈｉｖを処置する方法
EP2004632B1 (en) 2006-03-30 2014-03-12 Janssen R&D Ireland Hiv inhibiting 5-amido substituted pyrimidines
WO2008037783A1 (en) * 2006-09-29 2008-04-03 Tibotec Pharmaceuticals Ltd. Process for preparing 2-oxo-2,5-dihydro-1h-pyrido[3,2-b]indole-3-carbonitriles
US9006243B2 (en) 2006-12-29 2015-04-14 Janssen R&D Ireland HIV inhibiting 6-substituted pyrimidines
CN106045965A (zh) 2006-12-29 2016-10-26 爱尔兰詹森科学公司 抑制hiv的5,6‑取代的嘧啶类化合物
AR065720A1 (es) 2007-03-14 2009-06-24 Tibotec Pharm Ltd Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso.
US8426434B2 (en) 2007-07-12 2013-04-23 Tibotec Pharmaceuticals Ltd. Crystalline form of 4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]-amino]-2-pyrimidinyl]amino]benzonitrile
WO2010085582A1 (en) * 2009-01-23 2010-07-29 Bristol-Myers Squibb Company Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
WO2010085584A1 (en) 2009-01-23 2010-07-29 Bristol-Myers Squibb Company Pyrazole-i, 2, 4 -oxad iazole derivatives as s.phing0sine-1-ph0sphate agonists
WO2010085581A1 (en) * 2009-01-23 2010-07-29 Bristol-Myers Squibb Company Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
MX2011010582A (es) 2009-04-09 2011-10-19 Boehringer Ingelheim Int Inhibidores de la replicacion del vih.
JP2013526496A (ja) * 2010-05-14 2013-06-24 アフェクティス ファーマシューティカルズ アーゲー Ｐ２ｘ７ｒ拮抗剤の新規調製方法
EP2599769A4 (en) 2010-07-28 2015-05-20 Sumitomo Chemical Co PROCESS FOR PREPARING A CARBOXYLIC ACID AMID
UA115576C2 (uk) 2012-12-06 2017-11-27 Байєр Фарма Акцієнгезелльшафт Похідні бензимідазолу як антагоністи ер4
MX2018006474A (es) * 2015-12-02 2018-08-01 Syngenta Participations Ag Derivados de oxadiazol microbicidas.
WO2017222951A1 (en) * 2016-06-23 2017-12-28 Merck Sharp & Dohme Corp. 3-aryl and heteroaryl substituted 5-trifluoromethyl oxadiazoles as histone deacetylase 6 (hdac6) inhibitors
KR200486209Y1 (ko) 2016-07-05 2018-04-16 박우 편육 가공기구
CN108299428B (zh) * 2018-04-04 2019-09-27 山东大学 8-胺基-7-甲酸甲酯-吡嗪骈吡啶酮衍生物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002059123A2 (en) 2000-12-18 2002-08-01 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds
AU2002246658A1 (en) * 2000-12-18 2002-07-24 Makarov, Vadim Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
EA200500822A1 (ru) 2005-12-29
HRP20050543A2 (en) 2006-09-30
AU2003296760B2 (en) 2009-11-19
BR0316209A (pt) 2005-09-27
WO2004046143A1 (en) 2004-06-03
NO20052884D0 (no) 2005-06-14
MXPA05005146A (es) 2005-07-22
CN1738816A (zh) 2006-02-22
CN100457754C (zh) 2009-02-04
AP1927A (en) 2008-12-10
US7608726B2 (en) 2009-10-27
PL376683A1 (pl) 2006-01-09
NZ540321A (en) 2007-09-28
CA2506316A1 (en) 2004-06-03
US20060173000A1 (en) 2006-08-03
EP1594870B1 (en) 2011-05-11
EA009871B1 (ru) 2008-04-28
AP2005003334A0 (en) 2005-06-30
AU2003296760A1 (en) 2004-06-15
EP1594870A1 (en) 2005-11-16
US20100048563A1 (en) 2010-02-25
KR20050084621A (ko) 2005-08-26
JP2006508145A (ja) 2006-03-09

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