DK119785D0 - Insulinpraeparat - Google Patents

Insulinpraeparat

Info

Publication number
DK119785D0
DK119785D0 DK119785A DK119785A DK119785D0 DK 119785 D0 DK119785 D0 DK 119785D0 DK 119785 A DK119785 A DK 119785A DK 119785 A DK119785 A DK 119785A DK 119785 D0 DK119785 D0 DK 119785D0
Authority
DK
Denmark
Prior art keywords
pct
sec
insulin preparation
date
insulin derivatives
Prior art date
Application number
DK119785A
Other languages
English (en)
Inventor
Per Balschmidt
Finn Benned Hansen
Original Assignee
Nordisk Gentofte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Gentofte filed Critical Nordisk Gentofte
Priority to DK119785A priority Critical patent/DK119785D0/da
Publication of DK119785D0 publication Critical patent/DK119785D0/da
Priority to EP86901826A priority patent/EP0216832B1/en
Priority to JP61501710A priority patent/JPS62502196A/ja
Priority to PCT/DK1986/000022 priority patent/WO1986005496A1/en
Priority to PCT/DK1986/000023 priority patent/WO1986005497A1/en
Priority to EP86901827A priority patent/EP0216833B1/en
Priority to JP61501709A priority patent/JPS62502538A/ja
Priority to DE8686901826T priority patent/DE3673737D1/de
Priority to AU56226/86A priority patent/AU5622686A/en
Priority to DE8686901827T priority patent/DE3687500T2/de
Priority to AT86901827T priority patent/ATE84546T1/de
Priority to AU56227/86A priority patent/AU596968B2/en
Priority to IL78160A priority patent/IL78160A/xx
Priority to US07/002,672 priority patent/US5028586A/en
Priority to AT86901826T priority patent/ATE56022T1/de
Priority to FI864559A priority patent/FI864559L/fi
Priority to IL78161A priority patent/IL78161A0/xx
Priority to FI864560A priority patent/FI93460C/fi
Priority to DK545786A priority patent/DK159856C/da
Priority to NO864556A priority patent/NO174278C/no
Priority to DK545686A priority patent/DK545686D0/da
Priority to NO864555A priority patent/NO864555D0/no
Priority to US07/630,835 priority patent/US5157021A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK119785A 1985-03-15 1985-03-15 Insulinpraeparat DK119785D0 (da)

Priority Applications (23)

Application Number Priority Date Filing Date Title
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat
IL78161A IL78161A0 (en) 1985-03-15 1986-03-14 Insulin derivatives and pharmaceutical preparations containing them
AT86901827T ATE84546T1 (de) 1985-03-15 1986-03-14 Insulinabkoemmlinge und arzneimittel die diese enthalten.
IL78160A IL78160A (en) 1985-03-15 1986-03-14 Insulin derivatives and pharmaceutical preparations containing them
PCT/DK1986/000022 WO1986005496A1 (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives
PCT/DK1986/000023 WO1986005497A1 (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives
EP86901827A EP0216833B1 (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives
JP61501709A JPS62502538A (ja) 1985-03-15 1986-03-14 新規インシユリン誘導体およびこれら誘導体を含有する医薬製剤
DE8686901826T DE3673737D1 (de) 1985-03-15 1986-03-14 Insulinabkoemmlinge und arzneimittel die diese enthalten.
AU56226/86A AU5622686A (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives
DE8686901827T DE3687500T2 (de) 1985-03-15 1986-03-14 Insulinabkoemmlinge und arzneimittel die diese enthalten.
EP86901826A EP0216832B1 (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives
AU56227/86A AU596968B2 (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives
JP61501710A JPS62502196A (ja) 1985-03-15 1986-03-14 新規なインシユリン誘導体およびこれら誘導体を含有する製剤
US07/002,672 US5028586A (en) 1985-03-15 1986-03-14 Insulin derivatives and pharmaceutical preparations containing these derivatives
AT86901826T ATE56022T1 (de) 1985-03-15 1986-03-14 Insulinabkoemmlinge und arzneimittel die diese enthalten.
FI864559A FI864559L (fi) 1985-03-15 1986-03-14 Nya insulinderivat och farmaceutiska preparat innehaollande dessa derivat.
FI864560A FI93460C (fi) 1985-03-15 1986-11-10 Menetelmä uusien insuliinijohdannaisten valmistamiseksi
DK545786A DK159856C (da) 1985-03-15 1986-11-14 Humaninsulinderivater og farmaceutiske praeparater, som indeholder disse derivater
NO864556A NO174278C (no) 1985-03-15 1986-11-14 Fremgangsmåte ved fremstilling av insulinderivat
DK545686A DK545686D0 (da) 1985-03-15 1986-11-14 Insulinderivater og farmaceutiske praeparater, som indeholder disse derivater
NO864555A NO864555D0 (no) 1985-03-15 1986-11-14 Fremgangsmaate og fremstilling av insulinpreparat.
US07/630,835 US5157021A (en) 1985-03-15 1990-12-20 Insulin derivatives and pharmaceutical preparations containing these derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat

Publications (1)

Publication Number Publication Date
DK119785D0 true DK119785D0 (da) 1985-03-15

Family

ID=8102063

Family Applications (3)

Application Number Title Priority Date Filing Date
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat
DK545786A DK159856C (da) 1985-03-15 1986-11-14 Humaninsulinderivater og farmaceutiske praeparater, som indeholder disse derivater
DK545686A DK545686D0 (da) 1985-03-15 1986-11-14 Insulinderivater og farmaceutiske praeparater, som indeholder disse derivater

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK545786A DK159856C (da) 1985-03-15 1986-11-14 Humaninsulinderivater og farmaceutiske praeparater, som indeholder disse derivater
DK545686A DK545686D0 (da) 1985-03-15 1986-11-14 Insulinderivater og farmaceutiske praeparater, som indeholder disse derivater

Country Status (11)

Country Link
US (1) US5028586A (da)
EP (2) EP0216832B1 (da)
JP (2) JPS62502538A (da)
AT (2) ATE84546T1 (da)
AU (2) AU596968B2 (da)
DE (2) DE3687500T2 (da)
DK (3) DK119785D0 (da)
FI (2) FI864559L (da)
IL (2) IL78161A0 (da)
NO (2) NO864555D0 (da)
WO (2) WO1986005496A1 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US5157021A (en) * 1985-03-15 1992-10-20 Novo Nordisk A/S Insulin derivatives and pharmaceutical preparations containing these derivatives
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
FI884914A0 (fi) * 1987-02-25 1988-10-24 Novo Industri As Nya insulinderivat.
BR8803346A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina purificada
BR8803345A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina humana purificada
KR900701842A (ko) * 1988-07-20 1990-12-04 헨리 브뢰늄 인간 인슐린 동족체와 그를 포함하는 제제
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
AU9172991A (en) 1990-12-07 1992-07-08 Cnc Development, Inc. Catalytic chemical reactor
DK33591D0 (da) * 1991-02-27 1991-02-27 Novo Nordisk As
US5656590A (en) * 1991-05-24 1997-08-12 Amylin Pharmaceuticals, Inc. Treatment of anorexia and related states
US5461031A (en) * 1994-06-16 1995-10-24 Eli Lilly And Company Monomeric insulin analog formulations
AUPO269996A0 (en) * 1996-10-01 1996-10-24 Walter And Eliza Hall Institute Of Medical Research, The A method of prophylaxis and treatment
US5898067A (en) * 1997-02-07 1999-04-27 Novo Nordisk A/S Crystallization of proteins
BR0315818A (pt) * 2002-11-01 2005-09-13 Antares Pharma Inc Método de reduzir os nìveis de glicose sanguìnea médios em um paciente dependente de insulina
EP2033662B1 (en) 2004-01-21 2012-10-17 Novo Nordisk Health Care AG Transglutaminase mediated conjugation of peptides
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
US20090069216A1 (en) * 2006-02-21 2009-03-12 Novo Nordisk A/S Single-Chain Insulin Analogues and Pharmaceutical Formulations Thereof
AU2009210570B2 (en) * 2008-01-30 2014-11-20 Indiana University Research And Technology Corporation Ester-based insulin prodrugs
CN102300580A (zh) * 2008-12-19 2011-12-28 印第安纳大学研究及科技有限公司 二肽连接的药剂
CN102325539A (zh) 2008-12-19 2012-01-18 印第安纳大学研究及科技有限公司 基于酰胺的胰高血糖素超家族肽前药
JP5912112B2 (ja) 2010-06-24 2016-04-27 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ アミド系インスリンプロドラッグ
US9573987B2 (en) 2011-12-20 2017-02-21 Indiana University Research And Technology Corporation CTP-based insulin analogs for treatment of diabetes
AU2013323669B2 (en) 2012-09-26 2018-03-01 Indiana University Research And Technology Corporation Insulin analog dimers
WO2014158900A1 (en) 2013-03-14 2014-10-02 Indiana University Research And Technology Corporation Insulin-incretin conjugates
WO2016049174A1 (en) 2014-09-24 2016-03-31 Indiana University Research And Technology Corporation Lipidated amide-based insulin prodrugs
ES2822994T3 (es) 2014-09-24 2021-05-05 Univ Indiana Res & Tech Corp Conjugados de incretina-insulina

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
DK146482C (da) * 1979-04-13 1986-10-06 Shionogi & Co Fremgangsmaade til fremstilling af et b30-threonin-insulin
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
US4421685A (en) * 1980-03-27 1983-12-20 Eli Lilly And Company Process for producing an insulin
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider

Also Published As

Publication number Publication date
DE3687500T2 (de) 1993-07-01
IL78160A (en) 1991-06-10
NO864555L (no) 1986-11-14
ATE56022T1 (de) 1990-09-15
JPS62502538A (ja) 1987-10-01
NO174278C (no) 1994-04-13
FI864559A0 (fi) 1986-11-10
FI864559A7 (fi) 1986-11-10
NO864555D0 (no) 1986-11-14
JPS62502196A (ja) 1987-08-27
AU5622786A (en) 1986-10-13
DK159856C (da) 1991-05-06
FI864559L (fi) 1986-11-10
FI864560L (fi) 1986-11-10
NO864556L (no) 1986-11-14
AU596968B2 (en) 1990-05-24
DK545786A (da) 1986-11-14
ATE84546T1 (de) 1993-01-15
EP0216833A1 (en) 1987-04-08
EP0216832B1 (en) 1990-08-29
AU5622686A (en) 1986-10-13
EP0216832A1 (en) 1987-04-08
IL78161A0 (en) 1986-07-31
DE3687500D1 (de) 1993-02-25
US5028586A (en) 1991-07-02
DK159856B (da) 1990-12-17
DK545686A (da) 1986-11-14
DE3673737D1 (de) 1990-10-04
DK545686D0 (da) 1986-11-14
IL78160A0 (en) 1986-07-31
WO1986005497A1 (en) 1986-09-25
DK545786D0 (da) 1986-11-14
FI864560A0 (fi) 1986-11-10
EP0216833B1 (en) 1993-01-13
NO864556D0 (no) 1986-11-14
NO174278B (no) 1994-01-03
WO1986005496A1 (en) 1986-09-25
FI93460B (fi) 1994-12-30
FI93460C (fi) 1995-04-10

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Legal Events

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AHS Application shelved for other reasons than non-payment