DK347086D0 - Novel peptides - Google Patents

Novel peptides

Info

Publication number
DK347086D0
DK347086D0 DK347086A DK347086A DK347086D0 DK 347086 D0 DK347086 D0 DK 347086D0 DK 347086 A DK347086 A DK 347086A DK 347086 A DK347086 A DK 347086A DK 347086 D0 DK347086 D0 DK 347086D0
Authority
DK
Denmark
Prior art keywords
amino acid
solutions
insulin
asn
substituted
Prior art date
Application number
DK347086A
Other languages
English (en)
Inventor
Jan Markussen
Kjeld Norris
Liselotte Langkjaer
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8123250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK347086(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK347086A priority Critical patent/DK347086D0/da
Publication of DK347086D0 publication Critical patent/DK347086D0/da
Priority to HU873343A priority patent/HU203371B/hu
Priority to DE2000175024 priority patent/DE10075024I1/de
Priority to EP87306405A priority patent/EP0254516B1/en
Priority to AT87306405T priority patent/ATE99699T1/de
Priority to DK376187A priority patent/DK160880C/da
Priority to KR1019870007832A priority patent/KR880001701A/ko
Priority to NZ221130A priority patent/NZ221130A/xx
Priority to YU01353/87A priority patent/YU135387A/xx
Priority to ZA875295A priority patent/ZA875295B/xx
Priority to NO873018A priority patent/NO170978C/no
Priority to DD87305161A priority patent/DD273839A5/de
Priority to MYPI87001062A priority patent/MY102873A/en
Priority to ES87306405T priority patent/ES2061504T3/es
Priority to IL83243A priority patent/IL83243A/xx
Priority to DE3788684T priority patent/DE3788684T2/de
Priority to CN198787104988A priority patent/CN87104988A/zh
Priority to FI873185A priority patent/FI873185L/fi
Priority to US07/075,387 priority patent/US4946828A/en
Priority to PT85355A priority patent/PT85355B/pt
Priority to AU75916/87A priority patent/AU612324B2/en
Priority to JP62180168A priority patent/JPS6399096A/ja
Priority to US07/424,503 priority patent/US5008241A/en
Priority to NL300018C priority patent/NL300018I1/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK347086A 1985-03-12 1986-07-21 Novel peptides DK347086D0 (da)

Priority Applications (24)

Application Number Priority Date Filing Date Title
DK347086A DK347086D0 (da) 1986-07-21 1986-07-21 Novel peptides
PT85355A PT85355B (pt) 1986-07-21 1987-07-20 Processo para a preparacao de novos peptidos
AU75916/87A AU612324B2 (en) 1986-07-21 1987-07-20 Novel peptides and injectable solutions having prolonged insulin action
ZA875295A ZA875295B (en) 1986-07-21 1987-07-20 Novel peptides
MYPI87001062A MY102873A (en) 1986-07-21 1987-07-20 Novel peptides
EP87306405A EP0254516B1 (en) 1986-07-21 1987-07-20 Novel Peptides
AT87306405T ATE99699T1 (de) 1986-07-21 1987-07-20 Peptide.
DK376187A DK160880C (da) 1986-07-21 1987-07-20 Insulinderivater samt injicerbare oploesninger indeholdende disse
KR1019870007832A KR880001701A (ko) 1986-07-21 1987-07-20 신규한 펩티드
NZ221130A NZ221130A (en) 1986-07-21 1987-07-20 Insulin analogues with greater positive charge than human insulin at neutral ph
YU01353/87A YU135387A (en) 1986-07-21 1987-07-20 Process for obtaining new peptides
HU873343A HU203371B (en) 1986-07-21 1987-07-20 Process for producing new insulin derivatives and injection solutions comprising same
NO873018A NO170978C (no) 1986-07-21 1987-07-20 Analogifremgangsmaate ved fremstilling av nye peptider
DD87305161A DD273839A5 (de) 1986-07-21 1987-07-20 Verfahren zur herstellung neuer insulinderivate
DE2000175024 DE10075024I1 (de) 1986-07-21 1987-07-20 Peptide
ES87306405T ES2061504T3 (es) 1986-07-21 1987-07-20 Nuevos peptidos.
IL83243A IL83243A (en) 1986-07-21 1987-07-20 Insulin derivatives optionally having alterations in the a4, a17, a21, b13, b21 and b27 positions
DE3788684T DE3788684T2 (de) 1986-07-21 1987-07-20 Peptide.
CN198787104988A CN87104988A (zh) 1986-07-21 1987-07-20 新的多肽
FI873185A FI873185L (fi) 1986-07-21 1987-07-20 Nya peptider.
US07/075,387 US4946828A (en) 1985-03-12 1987-07-20 Novel insulin peptides
JP62180168A JPS6399096A (ja) 1986-07-21 1987-07-21 インシュリン誘導体
US07/424,503 US5008241A (en) 1985-03-12 1989-10-20 Novel insulin peptides
NL300018C NL300018I1 (nl) 1986-07-21 2000-09-15 Nieuwe peptiden.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK347086A DK347086D0 (da) 1986-07-21 1986-07-21 Novel peptides

Publications (1)

Publication Number Publication Date
DK347086D0 true DK347086D0 (da) 1986-07-21

Family

ID=8123250

Family Applications (1)

Application Number Title Priority Date Filing Date
DK347086A DK347086D0 (da) 1985-03-12 1986-07-21 Novel peptides

Country Status (20)

Country Link
EP (1) EP0254516B1 (da)
JP (1) JPS6399096A (da)
KR (1) KR880001701A (da)
CN (1) CN87104988A (da)
AT (1) ATE99699T1 (da)
AU (1) AU612324B2 (da)
DD (1) DD273839A5 (da)
DE (2) DE3788684T2 (da)
DK (1) DK347086D0 (da)
ES (1) ES2061504T3 (da)
FI (1) FI873185L (da)
HU (1) HU203371B (da)
IL (1) IL83243A (da)
MY (1) MY102873A (da)
NL (1) NL300018I1 (da)
NO (1) NO170978C (da)
NZ (1) NZ221130A (da)
PT (1) PT85355B (da)
YU (1) YU135387A (da)
ZA (1) ZA875295B (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE62879B1 (en) * 1987-02-25 1995-03-08 Novo Nordisk As Novel insulin derivatives
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
JPH03506023A (ja) * 1988-07-20 1991-12-26 ノボ ノルデイスク アクツイエセルスカプ ポリペプチド
DE3827533A1 (de) * 1988-08-13 1990-02-15 Hoechst Ag Pharmazeutische zubereitung zur behandlung des diabetes mellitus
DE3837825A1 (de) * 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
HUT56857A (en) * 1988-12-23 1991-10-28 Novo Nordisk As Human insulin analogues
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
US5514646A (en) * 1989-02-09 1996-05-07 Chance; Ronald E. Insulin analogs modified at position 29 of the B chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
DE3936876A1 (de) * 1989-11-06 1991-05-23 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5474978A (en) * 1994-06-16 1995-12-12 Eli Lilly And Company Insulin analog formulations
US5693609A (en) * 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
US7316999B2 (en) 2000-06-02 2008-01-08 Novo Nordisk A/S Glucose dependent release of insulin from glucose sensing insulin derivatives
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE60236014D1 (de) 2001-11-19 2010-05-27 Novo Nordisk As Verfahren zur herstellung von insulinverbindungen
GB0206792D0 (en) 2002-03-22 2002-05-01 Leuven K U Res & Dev Normoglycemia
DE10227232A1 (de) 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
ATE505323T1 (de) 2003-06-27 2011-04-15 Novo Nordisk As Behälter für medizinische flüssigkeiten mit hoher wasserdampfsperre
DE602004029496D1 (de) 2003-12-22 2010-11-18 Novo Nordisk As Offbehälter zur lagerung von pharmazeutischen flüssigkeiten
ES2642214T3 (es) 2004-01-21 2017-11-15 Novo Nordisk Health Care Ag Conjugación de péptidos mediante transglutaminasa
DE102006031955A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
DE102006031962A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
WO2008049711A1 (en) 2006-10-27 2008-05-02 Novo Nordisk A/S Peptide extended insulins
JP5695909B2 (ja) * 2008-01-09 2015-04-08 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 極度に遅延した時間作用プロファイルを有する新規なインスリン誘導体
MY152979A (en) * 2008-01-09 2014-12-15 Sanofi Aventis Deutschland Novel insulin derivatives having an extremely delayed time-action profile
HUE032284T2 (en) 2008-03-18 2017-09-28 Novo Nordisk As Protease-stabilized, acylated insulin analogues
TWI451876B (zh) 2008-06-13 2014-09-11 Lilly Co Eli 聚乙二醇化之離脯胰島素化合物
EP2307441B1 (en) 2008-08-07 2016-03-23 Biocon Limited A process for preparation of insulin compounds
RS59913B1 (sr) 2008-10-17 2020-03-31 Sanofi Aventis Deutschland Kombinacija insulina i glp-1-agonista
CN102596175A (zh) 2009-07-06 2012-07-18 赛诺菲-安万特德国有限公司 含有甲硫氨酸的水性胰岛素制备物
US20120241356A1 (en) * 2009-07-06 2012-09-27 Sanofi-Aventis Deutschland Gmbh Heat- and vibration-stable insulin preparations
PT3345593T (pt) 2009-11-13 2023-11-27 Sanofi Aventis Deutschland Composição farmacêutica compreendendo despro36exendina- 4(1-39)-lys6-nh2 e metionina
MY180661A (en) 2009-11-13 2020-12-04 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist, an insulin and methionine
EP2460527A1 (en) 2010-01-21 2012-06-06 Sanofi Pharmaceutical composition for treating a metabolic syndrome
AR080884A1 (es) 2010-04-14 2012-05-16 Sanofi Aventis Conjugados de insulina-sirna
PL2611458T3 (pl) 2010-08-30 2017-02-28 Sanofi-Aventis Deutschland Gmbh Zastosowanie AVE0010 do produkcji leku do leczenia cukrzycy typu 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
EP2548570A1 (en) 2011-07-19 2013-01-23 Sanofi Pharmaceutical composition for treating a metabolic syndrome
AR087693A1 (es) 2011-08-29 2014-04-09 Sanofi Aventis Deutschland Combinacion farmaceutica para uso en el control glucemico en pacientes con diabetes de tipo 2
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
CN104364260B (zh) 2012-04-11 2017-02-22 诺和诺德股份有限公司 胰岛素制剂
US9656017B2 (en) 2014-06-20 2017-05-23 Howard E. Greene Infusion delivery devices and methods
EP3229828B1 (en) 2014-12-12 2023-04-05 Sanofi-Aventis Deutschland GmbH Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療
PE20210857A1 (es) 2016-12-16 2021-05-18 Novo Nordisk As Composiciones farmaceuticas que contienen insulina

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3033127A1 (de) * 1980-09-03 1982-04-08 Hoechst Ag, 6000 Frankfurt Neue analoga des insulins
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat

Also Published As

Publication number Publication date
PT85355B (pt) 1990-04-30
JPS6399096A (ja) 1988-04-30
PT85355A (en) 1987-08-01
NO873018D0 (no) 1987-07-20
HUT45271A (en) 1988-06-28
EP0254516A3 (en) 1990-06-27
KR880001701A (ko) 1988-04-26
NO170978B (no) 1992-09-28
YU135387A (en) 1988-10-31
NL300018I1 (nl) 2000-11-01
IL83243A0 (en) 1987-12-31
CN87104988A (zh) 1988-03-02
EP0254516B1 (en) 1994-01-05
DD273839A5 (de) 1989-11-29
EP0254516A2 (en) 1988-01-27
NO170978C (no) 1993-01-06
NO873018L (no) 1988-01-22
ZA875295B (en) 1988-01-21
AU7591687A (en) 1988-01-28
FI873185A0 (fi) 1987-07-20
DE10075024I1 (de) 2000-11-09
IL83243A (en) 1993-01-14
MY102873A (en) 1993-03-31
DE3788684T2 (de) 1994-05-19
ATE99699T1 (de) 1994-01-15
NZ221130A (en) 1990-08-28
FI873185A7 (fi) 1988-01-22
FI873185L (fi) 1988-01-22
DE3788684D1 (de) 1994-02-17
ES2061504T3 (es) 1994-12-16
HU203371B (en) 1991-07-29
AU612324B2 (en) 1991-07-11

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Legal Events

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AHS Application shelved for other reasons than non-payment