DK1087976T3 - Polymorf form af clopidogrel-hydrogensulfat - Google Patents

Polymorf form af clopidogrel-hydrogensulfat

Info

Publication number
DK1087976T3
DK1087976T3 DK99923711T DK99923711T DK1087976T3 DK 1087976 T3 DK1087976 T3 DK 1087976T3 DK 99923711 T DK99923711 T DK 99923711T DK 99923711 T DK99923711 T DK 99923711T DK 1087976 T3 DK1087976 T3 DK 1087976T3
Authority
DK
Denmark
Prior art keywords
hydrogen sulfate
polymorphic form
clopidogrel hydrogen
clopidogrel
polymorphic
Prior art date
Application number
DK99923711T
Other languages
Danish (da)
English (en)
Inventor
Andre Bousquet
Bertrand Castro
Jean Saint-Germain
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9527349&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1087976(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Application granted granted Critical
Publication of DK1087976T3 publication Critical patent/DK1087976T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK99923711T 1998-06-15 1999-06-10 Polymorf form af clopidogrel-hydrogensulfat DK1087976T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9807464A FR2779726B1 (fr) 1998-06-15 1998-06-15 Forme polymorphe de l'hydrogenosulfate de clopidogrel
PCT/FR1999/001371 WO1999065915A1 (fr) 1998-06-15 1999-06-10 Forme polymorphe de l'hydrogenosulfate de clopidogrel

Publications (1)

Publication Number Publication Date
DK1087976T3 true DK1087976T3 (da) 2002-12-02

Family

ID=9527349

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99923711T DK1087976T3 (da) 1998-06-15 1999-06-10 Polymorf form af clopidogrel-hydrogensulfat

Country Status (43)

Country Link
US (2) US6429210B1 (de)
EP (1) EP1087976B1 (de)
JP (1) JP3641584B2 (de)
KR (1) KR100511238B1 (de)
CN (1) CN1128805C (de)
AP (1) AP1344A (de)
AR (1) AR014854A1 (de)
AT (1) ATE222256T1 (de)
AU (1) AU752170B2 (de)
BG (1) BG64508B1 (de)
BR (1) BR9911219A (de)
CA (1) CA2334870C (de)
CO (1) CO5040084A1 (de)
CZ (1) CZ299654B6 (de)
DE (1) DE69902536T2 (de)
DK (1) DK1087976T3 (de)
DZ (1) DZ2817A1 (de)
EA (1) EA002386B1 (de)
EE (1) EE03972B1 (de)
EG (1) EG24015A (de)
ES (1) ES2181439T3 (de)
FR (1) FR2779726B1 (de)
HR (1) HRP20000863B1 (de)
HU (1) HU225871B1 (de)
ID (1) ID28264A (de)
IL (2) IL139790A0 (de)
IS (1) IS2469B (de)
ME (1) ME00686B (de)
MY (1) MY129439A (de)
NO (1) NO327161B1 (de)
NZ (1) NZ507914A (de)
OA (1) OA11567A (de)
PL (1) PL201894B1 (de)
PT (1) PT1087976E (de)
RS (1) RS49870B (de)
SA (1) SA99200321B1 (de)
SK (1) SK286340B6 (de)
TR (1) TR200003417T2 (de)
TW (1) TW562805B (de)
UA (1) UA70323C2 (de)
UY (1) UY25693A1 (de)
WO (1) WO1999065915A1 (de)
ZA (1) ZA200006386B (de)

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CN103524528A (zh) * 2013-09-16 2014-01-22 吉林省博大伟业制药有限公司 一种改进的ⅱ型硫酸氢氯吡格雷结晶制备方法
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CN107698620A (zh) 2015-06-23 2018-02-16 江苏天士力帝益药业有限公司 一种氘代噻吩并哌啶衍生物、制备方法及其应用
JP2020507621A (ja) 2017-01-23 2020-03-12 ドン ファ ファーマシューティカル カンパニー リミテッド ＨＭＧ−ＣｏＡ還元酵素阻害剤およびクロピドグレルを含む複合製剤
CN107163060B (zh) * 2017-05-24 2021-03-02 常州制药厂有限公司 一种硫酸氢氯吡格雷晶型ii制备方法
CN107337683B (zh) * 2017-08-16 2019-08-16 中荣凯特（北京）生物科技有限公司 一种噻吩并吡啶类衍生物硫酸氢盐的晶型ⅱ及其制备方法和应用
CN109438467B (zh) * 2018-11-14 2021-03-26 四川青木制药有限公司 一种硫酸氢氯吡格雷ⅱ型球形结晶的制备方法
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Family Cites Families (2)

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Publication number Priority date Publication date Assignee Title
FR2623810B2 (fr) 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
FR2664276B1 (fr) 1990-07-04 1992-10-23 Sanofi Sa Derive thienyl-2 glycidique, son procede de preparation et son utilisation comme intermediaire de synthese.

Also Published As

Publication number Publication date
EP1087976B1 (de) 2002-08-14
SA99200321B1 (ar) 2006-10-11
AU752170B2 (en) 2002-09-05
DE69902536T2 (de) 2003-03-13
HU225871B1 (en) 2007-11-28
EE03972B1 (et) 2003-02-17
HRP20000863A2 (en) 2001-10-31
JP2002518399A (ja) 2002-06-25
PL201894B1 (pl) 2009-05-29
SK19092000A3 (sk) 2001-05-10
BG104987A (en) 2001-11-30
ME00686B (me) 2008-08-07
NO20006395D0 (no) 2000-12-14
UA70323C2 (uk) 2004-10-15
PT1087976E (pt) 2002-11-29
US6504030B1 (en) 2003-01-07
NO20006395L (no) 2001-02-15
ZA200006386B (en) 2001-05-07
AP1344A (en) 2004-12-15
AR014854A1 (es) 2001-04-11
OA11567A (en) 2004-05-24
KR100511238B1 (ko) 2005-08-31
HK1033829A1 (en) 2001-09-28
CA2334870C (en) 2005-03-15
EE200000745A (et) 2002-04-15
ES2181439T3 (es) 2003-02-16
IL139790A (en) 2006-10-05
US20020198229A1 (en) 2002-12-26
BR9911219A (pt) 2001-03-06
TW562805B (en) 2003-11-21
CO5040084A1 (es) 2001-05-29
NZ507914A (en) 2002-11-26
NO327161B1 (no) 2009-05-04
MY129439A (en) 2007-04-30
DE69902536D1 (en) 2002-09-19
EA200001187A1 (ru) 2001-08-27
CZ20004637A3 (cs) 2001-04-11
US6429210B1 (en) 2002-08-06
IS5716A (is) 2000-11-17
AU4048399A (en) 2000-01-05
EA002386B1 (ru) 2002-04-25
TR200003417T2 (tr) 2001-03-21
JP3641584B2 (ja) 2005-04-20
IL139790A0 (en) 2002-02-10
WO1999065915A1 (fr) 1999-12-23
CN1305483A (zh) 2001-07-25
EG24015A (en) 2008-03-24
RS49870B (sr) 2008-08-07
CZ299654B6 (cs) 2008-10-08
KR20010052835A (ko) 2001-06-25
FR2779726A1 (fr) 1999-12-17
UY25693A1 (es) 2000-03-31
HUP0104343A2 (hu) 2002-03-28
HRP20000863B1 (en) 2003-04-30
EP1087976A1 (de) 2001-04-04
CA2334870A1 (en) 1999-12-23
PL344998A1 (en) 2001-11-19
IS2469B (is) 2008-12-15
BG64508B1 (bg) 2005-05-31
YU77700A (sh) 2003-04-30
SK286340B6 (en) 2008-07-07
AP2000001979A0 (en) 2000-12-31
HUP0104343A3 (en) 2003-03-28
CN1128805C (zh) 2003-11-26
FR2779726B1 (fr) 2001-05-18
DZ2817A1 (fr) 2004-06-02
ID28264A (id) 2001-05-10
ATE222256T1 (de) 2002-08-15

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