DK1123386T3 - Fremgangsmåde til fremstilling af chirale carboxylsyrer af nitriler ved hjælp af en nitrilase eller mikroorganismer, som indeholder et gen for nitrilasen - Google Patents

Fremgangsmåde til fremstilling af chirale carboxylsyrer af nitriler ved hjælp af en nitrilase eller mikroorganismer, som indeholder et gen for nitrilasen

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Publication number
DK1123386T3
DK1123386T3 DK99952558T DK99952558T DK1123386T3 DK 1123386 T3 DK1123386 T3 DK 1123386T3 DK 99952558 T DK99952558 T DK 99952558T DK 99952558 T DK99952558 T DK 99952558T DK 1123386 T3 DK1123386 T3 DK 1123386T3
Authority
DK
Denmark
Prior art keywords
nucleic acid
nitrilase
acid sequences
carboxylic acids
nitriles
Prior art date
Application number
DK99952558T
Other languages
Danish (da)
English (en)
Inventor
Ralf Mattes
Bernhard Hauer
Marion Ress-Loeschke
Thomas Friedrich
Dirk Engels
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK1123386T3 publication Critical patent/DK1123386T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK99952558T 1998-10-19 1999-10-13 Fremgangsmåde til fremstilling af chirale carboxylsyrer af nitriler ved hjælp af en nitrilase eller mikroorganismer, som indeholder et gen for nitrilasen DK1123386T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19848129A DE19848129A1 (de) 1998-10-19 1998-10-19 Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten
PCT/EP1999/007679 WO2000023577A1 (fr) 1998-10-19 1999-10-13 Procede de production d'acides carboxyliques chiraux a partir de nitriles, a l'aide d'une nitrilase ou de micro-organismes comportant un gene codant pour la nitrilase

Publications (1)

Publication Number Publication Date
DK1123386T3 true DK1123386T3 (da) 2007-05-07

Family

ID=7884933

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99952558T DK1123386T3 (da) 1998-10-19 1999-10-13 Fremgangsmåde til fremstilling af chirale carboxylsyrer af nitriler ved hjælp af en nitrilase eller mikroorganismer, som indeholder et gen for nitrilasen

Country Status (21)

Country Link
US (1) US6869783B1 (fr)
EP (1) EP1123386B1 (fr)
JP (1) JP4489298B2 (fr)
KR (1) KR100715744B1 (fr)
CN (1) CN100422319C (fr)
AT (1) ATE349517T1 (fr)
AU (1) AU765480B2 (fr)
BR (1) BR9914629A (fr)
CA (1) CA2347521C (fr)
CZ (1) CZ302494B6 (fr)
DE (2) DE19848129A1 (fr)
DK (1) DK1123386T3 (fr)
EE (1) EE05008B1 (fr)
ES (1) ES2280125T3 (fr)
HU (1) HU228092B1 (fr)
ID (1) ID29136A (fr)
IL (2) IL142397A0 (fr)
NO (1) NO327857B1 (fr)
PT (1) PT1123386E (fr)
WO (1) WO2000023577A1 (fr)
ZA (1) ZA200104066B (fr)

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US6455730B1 (en) 2000-08-04 2002-09-24 E. I. Du Pont De Nemours & Company Preparation of dicarboxylic acid monoesters from cyanocarboxylic acid esters
US20020137153A1 (en) * 2000-10-04 2002-09-26 Ramer Sandra W. Enantioselective production of amino carboxylic acids
FR2822460B1 (fr) * 2001-03-26 2005-04-29 Rhodia Chimie Sa Procede de preparation enantioselectif d'acides carboxyliques optiquement actifs par hydrolyse enzymatique de nitriles
DK2327765T3 (en) 2001-06-21 2015-07-13 Basf Enzymes Llc nitrilases
ITMI20011826A1 (it) * 2001-08-30 2003-03-02 Istituto Biochimico Italiano Microorganismo dotato di attivita' nitrile-idratasica/amidasica enantioselettiva e regioselettiva
PT1570060E (pt) 2002-12-02 2007-09-13 Basf Ag ''sistema de expressão indutível de l-ramnose''
AU2003296731B2 (en) * 2003-01-08 2009-07-09 Basf Aktiengesellschaft Methods for preserving and/or storing cells having a nitrilase or nitrile hydratase activity
CN100445375C (zh) * 2003-02-27 2008-12-24 巴斯福股份公司 经修饰的腈水解酶及它们在产生羧酸的方法中的用途
AT412092B (de) * 2003-02-27 2004-09-27 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung chiraler alpha-hydroxycarbonsäuren durch enzymatische hydrolyse von chiralen cyanhydrinen
CN102796769B (zh) * 2004-12-22 2014-06-04 纳幕尔杜邦公司 乙醇酸的酶促生产
US20100267100A1 (en) * 2007-03-21 2010-10-21 Ling Hua Enzymatic synthesis of optically pure beta-hydroxy carboxylic acids and their derivatives
US20090004720A1 (en) * 2007-06-26 2009-01-01 Ling Hua Smart Biocatalysts For Organic Synthesis
EP2338987A1 (fr) 2009-11-16 2011-06-29 ZYRUS Beteiligungsgesellschaft mbH & Co. Patente I KG Biocatalyseur de cellules entières
JP2013162746A (ja) * 2010-05-24 2013-08-22 Mitsui Chemicals Inc アミド化合物の製造方法
EP2643467A1 (fr) 2010-11-24 2013-10-02 Basf Se Procédé de fabrication d'alcools optiquement actifs n-hétérocycliques
KR101223666B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 ｏｒｎ을 이용한 카르복실산의 제조방법
KR101223664B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 ｒｍｎ１을 이용한 카르복실산의 제조방법
KR101223663B1 (ko) * 2011-01-26 2013-01-21 재단법인 경북해양바이오산업연구원 나이트릴레이즈 ｖｍｎ１을 이용한 카르복실산의 제조방법
KR101223665B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 ｒｍｎ２을 이용한 카르복실산의 제조방법
CA3172001A1 (fr) 2020-05-15 2021-11-18 Basf Se Procede ameliore pour la production d'isoprenoides
AU2022407155A1 (en) 2021-12-10 2024-06-20 Basf Se Herbicidal activity of alkyl phosphinates
CN118401535A (zh) 2021-12-10 2024-07-26 巴斯夫欧洲公司 草铵膦衍生物的酶促脱氨基甲酰化
CN118369324A (zh) 2021-12-10 2024-07-19 巴斯夫欧洲公司 使用基于乙内酰脲酶的工艺的草铵膦合成
KR20250124113A (ko) 2022-12-16 2025-08-19 바스프 에스이 신규한 에틸렌디아민-n,n'-디숙신산 (edds) 신타아제
TW202512923A (zh) 2023-06-13 2025-04-01 德商巴地斯顏料化工廠 使用基於醯胺酶之製程合成固殺草
EP4556568A1 (fr) 2023-11-17 2025-05-21 Basf Se Procédés biocatalytiques de production d'acide éthylènediamine-n,n'-disuccinique
WO2025104259A2 (fr) 2023-11-17 2025-05-22 Basf Se Formes cristallines d'acide s, s-éthylènediamine-n, n'-disuccinique, procédés et utilisations respectifs
WO2025104224A1 (fr) 2023-11-17 2025-05-22 Basf Se Variants de synthase d'edds
WO2025219237A1 (fr) 2024-04-15 2025-10-23 Basf Se Procédé de préparation d'acide 2-oxo-4-(hydroxy(méthyl)phosphinoyl)butyrique
WO2025219238A1 (fr) 2024-04-15 2025-10-23 Basf Se Procédé de production de l-glufosinate à partir d'un diol ou d'un dérivé de diol

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Also Published As

Publication number Publication date
CN1331743A (zh) 2002-01-16
WO2000023577A1 (fr) 2000-04-27
EP1123386A1 (fr) 2001-08-16
CN100422319C (zh) 2008-10-01
CZ20011382A3 (cs) 2002-03-13
HU228092B1 (en) 2012-10-29
ID29136A (id) 2001-08-02
DE59914102D1 (de) 2007-02-08
EE05008B1 (et) 2008-04-15
NO20011912L (no) 2001-04-18
EP1123386B1 (fr) 2006-12-27
HUP0104802A3 (en) 2005-10-28
IL142397A (en) 2008-03-20
CA2347521A1 (fr) 2000-04-27
US6869783B1 (en) 2005-03-22
PT1123386E (pt) 2007-03-30
NO327857B1 (no) 2009-10-05
JP2002527106A (ja) 2002-08-27
NO20011912D0 (no) 2001-04-18
ZA200104066B (en) 2002-07-01
IL142397A0 (en) 2002-03-10
ATE349517T1 (de) 2007-01-15
AU6470899A (en) 2000-05-08
BR9914629A (pt) 2001-06-26
JP4489298B2 (ja) 2010-06-23
DE19848129A1 (de) 2000-04-20
AU765480B2 (en) 2003-09-18
CZ302494B6 (cs) 2011-06-15
KR20010085938A (ko) 2001-09-07
EE200100232A (et) 2002-08-15
CA2347521C (fr) 2010-02-23
KR100715744B1 (ko) 2007-05-08
HUP0104802A2 (hu) 2002-04-29
ES2280125T3 (es) 2007-09-01

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