ATE471370T1 - Varianten von beta-glukosidasen - Google Patents
Varianten von beta-glukosidasenInfo
- Publication number
- ATE471370T1 ATE471370T1 AT04751000T AT04751000T ATE471370T1 AT E471370 T1 ATE471370 T1 AT E471370T1 AT 04751000 T AT04751000 T AT 04751000T AT 04751000 T AT04751000 T AT 04751000T AT E471370 T1 ATE471370 T1 AT E471370T1
- Authority
- AT
- Austria
- Prior art keywords
- beta
- glucosidases
- variants
- positions
- seq
- Prior art date
Links
- 102000005575 Cellulases Human genes 0.000 title abstract 2
- 108010084185 Cellulases Proteins 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 102000006995 beta-Glucosidase Human genes 0.000 abstract 2
- 108010047754 beta-Glucosidase Proteins 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2445—Beta-glucosidase (3.2.1.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01021—Beta-glucosidase (3.2.1.21)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Alternative & Traditional Medicine (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46776703P | 2003-05-02 | 2003-05-02 | |
| US52834203P | 2003-12-09 | 2003-12-09 | |
| PCT/US2004/013401 WO2004099228A2 (en) | 2003-05-02 | 2004-04-30 | Variants of beta-glucosidases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE471370T1 true ATE471370T1 (de) | 2010-07-15 |
Family
ID=33436742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04751000T ATE471370T1 (de) | 2003-05-02 | 2004-04-30 | Varianten von beta-glukosidasen |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7413888B2 (de) |
| EP (2) | EP1622921B1 (de) |
| AT (1) | ATE471370T1 (de) |
| DE (1) | DE602004027723D1 (de) |
| DK (2) | DK2228440T3 (de) |
| ES (2) | ES2393058T3 (de) |
| WO (1) | WO2004099228A2 (de) |
Families Citing this family (62)
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| CN101516906B (zh) | 2006-07-21 | 2013-11-06 | 诺维信股份有限公司 | 提高具有生物学活性之多肽的分泌的方法 |
| US9969993B2 (en) * | 2007-05-31 | 2018-05-15 | Novozymes, Inc. | Filamentous fungal host cells and methods of recombinantly producing proteins |
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| WO2009076655A2 (en) | 2007-12-13 | 2009-06-18 | University Of Washington | Synthetic enzymes derived from computational design |
| NZ598403A (en) | 2007-12-19 | 2012-07-27 | Novozymes As | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| NZ587525A (en) | 2008-03-06 | 2012-02-24 | Novozymes As | Polypeptides having beta-glucosidase activity and polynucleotides encoding same |
| WO2009132008A2 (en) * | 2008-04-21 | 2009-10-29 | Chromatin, Inc. | Methods and materials for processing a feedstock |
| CA2735271A1 (en) | 2008-08-29 | 2010-03-04 | Iogen Energy Corporation | Modified beta-glucosidases with improved stability |
| FR2935986B1 (fr) * | 2008-09-12 | 2012-11-23 | Inst Francais Du Petrole | Variants de beta-glucosidase a activite amelioree et leurs utilisations. |
| EP2857515B1 (de) | 2008-11-20 | 2018-02-21 | Novozymes Inc. | Polypeptide mit verstärkter amylolytischer Aktivität und Polynukleotide zur Codierung davon |
| US8338121B2 (en) | 2008-12-19 | 2012-12-25 | Novozymes, Inc. | Methods for determining cellulolytic enhancing activity of a polypeptide |
| CN102325879A (zh) | 2008-12-19 | 2012-01-18 | 诺维信股份有限公司 | 在纤维二糖脱氢酶存在下增加纤维素材料水解的方法 |
| CA2752818A1 (en) | 2009-02-26 | 2010-09-02 | Codexis, Inc. | Beta-glucosidase variant enzymes and related polynucleotides |
| WO2010129287A2 (en) | 2009-04-27 | 2010-11-11 | The Board Of Trustees Of The University Of Illinois | Hemicellulose-degrading enzymes |
| KR101183114B1 (ko) | 2009-05-08 | 2012-09-27 | 대한민국 | 백색부후균 유래 베타-글루코시다아제 유전자, 상기 유전자를 함유한 발현벡터, 상기 발현벡터로 형질전환된 형질전환체 및 상기 형질전환체의 제조방법 |
| CA2763836A1 (en) * | 2009-05-29 | 2010-12-02 | Iogen Energy Corporation | Novel beta-glucosidase enzymes |
| CA2765715A1 (en) | 2009-06-16 | 2010-12-23 | Codexis, Inc. | .beta.-glucosidase variants |
| WO2011035027A2 (en) | 2009-09-17 | 2011-03-24 | Novozymes, Inc. | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| EP2496694B1 (de) | 2009-11-06 | 2017-04-19 | Novozymes, Inc. | Zusammensetzungen zur verzuckerung von cellulosematerial |
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| DK2602317T3 (da) * | 2009-11-20 | 2017-11-13 | Danisco Us Inc | Beta-glucosidasevarianter med forbedrede egenskaber |
| BR112012012192A2 (pt) | 2009-11-25 | 2017-07-04 | Codexis Inc | b-glicosidades variantes recombinantes thermoascus aurantiacus para produção de açúcares fermentáveis a partir da biomassa celulósica |
| MX2012006016A (es) * | 2009-11-25 | 2012-06-25 | Codexis Inc | Variantes de beta-glucosidasa recombinante para produccion de azucares solubles de biomasa celulosica. |
| DK2513290T3 (en) | 2009-12-18 | 2016-01-25 | Novozymes Inc | Methods for Preparation of Polypeptides in Trichoderma Mutants with Protease Deficiency |
| CN102918151B (zh) | 2010-03-31 | 2015-09-09 | 诺维信股份有限公司 | 纤维二糖水解酶变体及编码其的多核苷酸 |
| CN102296053B (zh) * | 2010-06-25 | 2015-03-11 | 中国医学科学院药物研究所 | 一种7-木糖紫杉烷糖基水解酶、其基因的核苷酸序列及其应用 |
| BR112013002979A2 (pt) | 2010-08-12 | 2016-06-07 | Novozymes Inc | composição, e, método para degradar ou converter um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico. |
| US9816082B2 (en) | 2010-09-30 | 2017-11-14 | Novozymes, Inc. | Variants of polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| US10246691B2 (en) | 2010-09-30 | 2019-04-02 | Novozymes, Inc. | Variants of polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| ES2563209T3 (es) | 2010-10-01 | 2016-03-11 | Novozymes, Inc. | Variantes de beta-glucosidasa y polinucleótidos que codifican las mismas |
| WO2012068509A1 (en) | 2010-11-18 | 2012-05-24 | Novozymes, Inc. | Chimeric polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| EP2649188A1 (de) | 2010-12-06 | 2013-10-16 | Novozymes North America, Inc. | Verfahren zur hydrolyse von oligomeren in hemicellulosehaltiger flüssigkeit |
| EP2703484A4 (de) * | 2011-03-24 | 2014-12-31 | Asahi Glass Co Ltd | Transformant aus hefe der art schizosaccharomyces, herstellungsverfahren dafür, verfahren zur herstellung von beta-glucosidase und verfahren zur zersetzung von zellulose |
| EP2702153B1 (de) | 2011-04-28 | 2018-12-12 | Novozymes, Inc. | Polypeptide mit endoglucanase-aktivität und polynukleotide zu ihrer kodierung |
| DK2702162T3 (da) | 2011-04-29 | 2020-05-18 | Novozymes Inc | Fremgangsmåder til forbedring af nedbrydningen eller omdannelsen af celluloseholdigt materiale |
| BR112014003444A2 (pt) | 2011-08-19 | 2017-03-14 | Novozymes Inc | célula hospedeira recombinante, e, método para produzir um ácido c4-dicarboxílico |
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| DK2760885T3 (en) | 2011-09-30 | 2017-10-30 | Novozymes Inc | CHEMICAL POLYPEPTIDES WITH BETA-GLUCOSIDASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM |
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| CN104603269A (zh) | 2012-08-17 | 2015-05-06 | 诺维信公司 | 用于在丝状真菌菌株中共沉默基因表达的方法及其应用 |
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| CN106068077B (zh) | 2014-03-05 | 2019-06-07 | 诺维信公司 | 用于改进农作物的收获后特性的组合物和方法 |
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| EP3183339A1 (de) | 2014-08-20 | 2017-06-28 | Novozymes A/S | Xyloglucanendotransglycosylasevarianten und polynukleotide zur codierung davon |
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| CN104450651B (zh) * | 2014-12-09 | 2017-08-15 | 青岛蔚蓝生物集团有限公司 | 一种β‑葡萄糖苷酶突变体及其应用 |
| US10626430B2 (en) | 2015-01-20 | 2020-04-21 | Suntory Holdings Limited | Method for preparing mogroside having no β-1,6-glucoside bond |
| KR20180012254A (ko) | 2015-04-10 | 2018-02-05 | 코멧 바이오리파이닝 인코포레이티드 | 셀룰로스 바이오매스의 처리를 위한 방법 및 조성물 및 이에 의해 생성된 생성물 |
| CN107922896A (zh) * | 2015-06-30 | 2018-04-17 | 诺维信公司 | 衣物洗涤剂组合物、用于洗涤的方法和组合物的用途 |
| CN108368530A (zh) * | 2015-12-10 | 2018-08-03 | 帝斯曼知识产权资产管理有限公司 | β-葡糖苷酶及其用途 |
| CN105567662B (zh) * | 2016-01-28 | 2018-09-07 | 中国农业科学院饲料研究所 | 一种嗜热β-葡萄糖苷酶突变体-M36N及其编码基因和应用 |
| ES3002766T3 (en) | 2018-05-10 | 2025-03-07 | Comet Biorefining Inc | Compositions comprising glucose and hemicellulose and their use |
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| CN116334044B (zh) * | 2021-12-22 | 2025-09-23 | 湖南中烟工业有限责任公司 | 烟草烟碱积累相关基因NtBGLU1、蛋白及其应用 |
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-
2004
- 2004-04-30 ES ES10165162T patent/ES2393058T3/es not_active Expired - Lifetime
- 2004-04-30 AT AT04751000T patent/ATE471370T1/de not_active IP Right Cessation
- 2004-04-30 WO PCT/US2004/013401 patent/WO2004099228A2/en not_active Ceased
- 2004-04-30 ES ES04751000T patent/ES2347658T3/es not_active Expired - Lifetime
- 2004-04-30 US US10/836,063 patent/US7413888B2/en not_active Expired - Fee Related
- 2004-04-30 DE DE602004027723T patent/DE602004027723D1/de not_active Expired - Lifetime
- 2004-04-30 DK DK10165162.8T patent/DK2228440T3/da active
- 2004-04-30 EP EP04751000A patent/EP1622921B1/de not_active Expired - Lifetime
- 2004-04-30 DK DK04751000.3T patent/DK1622921T3/da active
- 2004-04-30 EP EP10165162A patent/EP2228440B1/de not_active Expired - Lifetime
-
2008
- 2008-06-26 US US12/147,333 patent/US7638616B2/en not_active Expired - Fee Related
-
2009
- 2009-12-16 US US12/639,642 patent/US8852913B2/en not_active Expired - Fee Related
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2014
- 2014-10-06 US US14/507,539 patent/US9080165B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US8852913B2 (en) | 2014-10-07 |
| EP2228440B1 (de) | 2012-08-22 |
| US7413888B2 (en) | 2008-08-19 |
| US20150099280A1 (en) | 2015-04-09 |
| US20090053765A1 (en) | 2009-02-26 |
| US7638616B2 (en) | 2009-12-29 |
| DK1622921T3 (da) | 2010-09-13 |
| ES2393058T3 (es) | 2012-12-18 |
| ES2347658T3 (es) | 2010-11-03 |
| DK2228440T3 (da) | 2013-01-02 |
| DE602004027723D1 (de) | 2010-07-29 |
| EP2228440A1 (de) | 2010-09-15 |
| US20100099146A1 (en) | 2010-04-22 |
| EP1622921A4 (de) | 2006-12-27 |
| WO2004099228A3 (en) | 2005-12-29 |
| WO2004099228A2 (en) | 2004-11-18 |
| EP1622921B1 (de) | 2010-06-16 |
| US9080165B2 (en) | 2015-07-14 |
| US20040253702A1 (en) | 2004-12-16 |
| EP1622921A2 (de) | 2006-02-08 |
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