DK1148049T3 - Krystallinsk [R-(R*,R*)]-2-(4-fluorphenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4- [(phenylamino)carbonyl]-1H-pyrrol-1-heptansyre-hemicalciumsalt (ATORVASTATIN) - Google Patents

Krystallinsk [R-(R*,R*)]-2-(4-fluorphenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4- [(phenylamino)carbonyl]-1H-pyrrol-1-heptansyre-hemicalciumsalt (ATORVASTATIN)

Info

Publication number
DK1148049T3
DK1148049T3 DK01116338T DK01116338T DK1148049T3 DK 1148049 T3 DK1148049 T3 DK 1148049T3 DK 01116338 T DK01116338 T DK 01116338T DK 01116338 T DK01116338 T DK 01116338T DK 1148049 T3 DK1148049 T3 DK 1148049T3
Authority
DK
Denmark
Prior art keywords
atorvastatin
phenylamino
methylethyl
fluorophenyl
pyrrole
Prior art date
Application number
DK01116338T
Other languages
English (en)
Inventor
Christopher A Briggs
Rex Allen Jennings
Robert A Wade
Kikuko Harasawa
Shigeru Ichikawa
Kazuo Minohara
Shinsuke Nakagawa
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21696090&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1148049(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of DK1148049T3 publication Critical patent/DK1148049T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
DK01116338T 1995-07-17 1996-07-08 Krystallinsk [R-(R*,R*)]-2-(4-fluorphenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4- [(phenylamino)carbonyl]-1H-pyrrol-1-heptansyre-hemicalciumsalt (ATORVASTATIN) DK1148049T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US145295P 1995-07-17 1995-07-17
PCT/US1996/011368 WO1997003959A1 (en) 1995-07-17 1996-07-08 Crystalline [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin)

Publications (1)

Publication Number Publication Date
DK1148049T3 true DK1148049T3 (da) 2005-03-29

Family

ID=21696090

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96924368T DK0848705T3 (da) 1995-07-17 1996-07-08 Krystallinsk [R-(R*,R*)]-2-(4-fluorphenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1- heptansyre-hemicalciumsalt (atorvastatin)
DK01116338T DK1148049T3 (da) 1995-07-17 1996-07-08 Krystallinsk [R-(R*,R*)]-2-(4-fluorphenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4- [(phenylamino)carbonyl]-1H-pyrrol-1-heptansyre-hemicalciumsalt (ATORVASTATIN)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK96924368T DK0848705T3 (da) 1995-07-17 1996-07-08 Krystallinsk [R-(R*,R*)]-2-(4-fluorphenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1- heptansyre-hemicalciumsalt (atorvastatin)

Country Status (37)

Country Link
US (1) US5969156A (da)
EP (2) EP0848705B1 (da)
JP (4) JP3296564B2 (da)
KR (2) KR100389518B1 (da)
CN (1) CN1087288C (da)
AR (2) AR003458A1 (da)
AT (3) ATE284868T1 (da)
AU (1) AU725424B2 (da)
BG (1) BG63630B1 (da)
BR (1) BR9609872A (da)
CA (1) CA2220018C (da)
CO (1) CO4700443A1 (da)
CY (1) CY2358B1 (da)
CZ (3) CZ294695B6 (da)
DE (2) DE69616808T2 (da)
DK (2) DK0848705T3 (da)
EA (1) EA000474B1 (da)
EE (1) EE03606B1 (da)
ES (2) ES2167587T3 (da)
GE (1) GEP20002029B (da)
HR (1) HRP960339B1 (da)
HU (1) HU223599B1 (da)
IL (7) IL128864A (da)
MX (1) MX9709099A (da)
NO (1) NO309898B1 (da)
NZ (1) NZ312907A (da)
PE (1) PE1898A1 (da)
PL (1) PL193479B1 (da)
PT (2) PT848705E (da)
RO (1) RO120070B1 (da)
SI (2) SI0848705T1 (da)
SK (1) SK284202B6 (da)
TW (1) TW486467B (da)
UA (1) UA51661C2 (da)
UY (2) UY24285A1 (da)
WO (1) WO1997003959A1 (da)
ZA (1) ZA966044B (da)

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