DK1165112T3 - Modulatorer af polysaccharider og anvendelser deraf - Google Patents

Modulatorer af polysaccharider og anvendelser deraf

Info

Publication number: DK1165112T3
Authority: DK; Denmark
Prior art keywords: glycosaminoglycan; peptides; sulfate; chitosan; mediated processes
Prior art date: 1999-03-26

Application number

DK00919594T

Other languages

Danish (da)

English (en)

Inventor

Akira Takashima

Mansour Mohamadzadeh

Mark E Mummert

Original Assignee

Univ Texas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-26

Filing date

2000-03-22

Publication date

2006-10-09

2000-03-22 Application filed by Univ Texas filed Critical Univ Texas

2006-10-09 Application granted granted Critical

2006-10-09 Publication of DK1165112T3 publication Critical patent/DK1165112T3/da

Links

150000004676 glycans Chemical class 0.000 title 1
229920001282 polysaccharide Polymers 0.000 title 1
239000005017 polysaccharide Substances 0.000 title 1
229920002683 Glycosaminoglycan Polymers 0.000 abstract 5
102000004196 processed proteins & peptides Human genes 0.000 abstract 5
108090000765 processed proteins & peptides Proteins 0.000 abstract 5
229920001661 Chitosan Polymers 0.000 abstract 2
208000015181 infectious disease Diseases 0.000 abstract 2
KXCLCNHUUKTANI-RBIYJLQWSA-N keratan Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@H](COS(O)(=O)=O)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@H](O[C@@H](O[C@H]3[C@H]([C@@H](COS(O)(=O)=O)O[C@@H](O)[C@@H]3O)O)[C@H](NC(C)=O)[C@H]2O)COS(O)(=O)=O)O[C@H](COS(O)(=O)=O)[C@@H]1O KXCLCNHUUKTANI-RBIYJLQWSA-N 0.000 abstract 2
230000001404 mediated effect Effects 0.000 abstract 2
KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 abstract 1
229920002101 Chitin Polymers 0.000 abstract 1
229920001287 Chondroitin sulfate Polymers 0.000 abstract 1
229920000045 Dermatan sulfate Polymers 0.000 abstract 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
229920000288 Keratan sulfate Polymers 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
230000008827 biological function Effects 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
KXKPYJOVDUMHGS-OSRGNVMNSA-N chondroitin sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](OS(O)(=O)=O)[C@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O1 KXKPYJOVDUMHGS-OSRGNVMNSA-N 0.000 abstract 1
229940059329 chondroitin sulfate Drugs 0.000 abstract 1
AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 abstract 1
229940051593 dermatan sulfate Drugs 0.000 abstract 1
230000006806 disease prevention Effects 0.000 abstract 1
239000003623 enhancer Substances 0.000 abstract 1
230000006870 function Effects 0.000 abstract 1
229920000669 heparin Polymers 0.000 abstract 1
229960002897 heparin Drugs 0.000 abstract 1
229920002674 hyaluronan Polymers 0.000 abstract 1
229960003160 hyaluronic acid Drugs 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
239000003068 molecular probe Substances 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Transplantation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polyesters Or Polycarbonates (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicinal Preparation (AREA)

DK00919594T 1999-03-26 2000-03-22 Modulatorer af polysaccharider og anvendelser deraf DK1165112T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US12647599P	1999-03-26	1999-03-26

Publications (1)

Publication Number	Publication Date
DK1165112T3 true DK1165112T3 (da)	2006-10-09

Family

ID=22425031

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00919594T DK1165112T3 (da)	1999-03-26	2000-03-22	Modulatorer af polysaccharider og anvendelser deraf

Country Status (13)

Country	Link
US (2)	US6653285B1 (fr)
EP (1)	EP1165112B1 (fr)
JP (1)	JP2002540161A (fr)
AT (1)	ATE328603T1 (fr)
AU (1)	AU774650B2 (fr)
CA (1)	CA2366604A1 (fr)
CY (1)	CY1105531T1 (fr)
DE (1)	DE60028558T2 (fr)
DK (1)	DK1165112T3 (fr)
ES (1)	ES2265928T3 (fr)
MX (1)	MXPA01009690A (fr)
PT (1)	PT1165112E (fr)
WO (1)	WO2000057896A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2004532203A (ja) *	2001-03-21	2004-10-21	ザ、ユニバーシティ、オブ、テキサス、システム	グリコサミノグリカンの阻害剤
EP1451323A2 (fr) *	2001-11-09	2004-09-01	Transition Therapeutics Inc.	Compositions pharmaceutiques de microciona prolifera d'eponge marine
ITPD20020003A1 (it) *	2002-01-11	2003-07-11	Fidia Advanced Biopolymers Srl	Biomateriali a base di acido ialuronico come terapia anti-angiogenicanella cura dei tumori.
US20060198800A1 (en) *	2003-08-14	2006-09-07	Natalie Dilallo	Skin care compositions including hexapeptide complexes and methods of their manufacture
WO2005016364A1 (fr) *	2003-08-14	2005-02-24	Guthy-Renker Corporation	Composition des soins de la peau comprenant des complexes d'hexapeptide et procedes de fabrication correspondants
WO2010006454A2 (fr)	2008-06-30	2010-01-21	Esbatech, An Alcon Biomedical Research Unit Llc	Polypeptides fonctionnalisés
WO2010003023A2 (fr) *	2008-07-01	2010-01-07	Zacharon Pharmaceuticals, Inc.	Inhibiteurs d'héparane sulfate
US8809009B2 (en)	2009-01-02	2014-08-19	Biomarin Pharmaceutical Inc.	Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker
US8592140B2 (en)	2009-01-02	2013-11-26	Biomarin Pharmaceutical Inc.	Detection of oligosaccharides
US8232073B2 (en)	2009-01-02	2012-07-31	Zacharon Pharmaceuticals, Inc.	Quantification of non-reducing end glycan residual compounds
US9029530B2 (en)	2009-01-02	2015-05-12	Biomarin Pharmaceutical Inc.	Detection of oligosaccharides
WO2011094731A2 (fr) *	2010-02-01	2011-08-04	The Board Of Trustees Of The Leland Stanford Junior University	Méthodes diagnostiques et traitement du diabète non insulinodépendant
EP3249662B1 (fr) *	2016-05-27	2020-05-13	Hanning Elektro-Werke GmbH & Co. KG	Moteur de pompe électrique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9207949D0 (en) *	1992-04-09	1992-05-27	Univ Manitoba	Molecular cloning of a novel hyaluronan receptor that mediates tumor cell motility
US5981478A (en) *	1993-11-24	1999-11-09	La Jolla Cancer Research Foundation	Integrin-binding peptides
CA2237051A1 (fr)	1997-12-19	1999-06-19	Eva A. Turley	Affinite amelioree de peptides lies a l'hyaluronan
AU2000278122A1 (en) *	2000-10-05	2002-04-15	Transition Therapeutics Inc.	Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans

2000
- 2000-03-22 AT AT00919594T patent/ATE328603T1/de not_active IP Right Cessation
- 2000-03-22 AU AU40255/00A patent/AU774650B2/en not_active Ceased
- 2000-03-22 EP EP00919594A patent/EP1165112B1/fr not_active Expired - Lifetime
- 2000-03-22 JP JP2000607646A patent/JP2002540161A/ja active Pending
- 2000-03-22 CA CA002366604A patent/CA2366604A1/fr not_active Abandoned
- 2000-03-22 WO PCT/US2000/007813 patent/WO2000057896A1/fr not_active Ceased
- 2000-03-22 ES ES00919594T patent/ES2265928T3/es not_active Expired - Lifetime
- 2000-03-22 DK DK00919594T patent/DK1165112T3/da active
- 2000-03-22 DE DE60028558T patent/DE60028558T2/de not_active Expired - Fee Related
- 2000-03-22 US US09/532,709 patent/US6653285B1/en not_active Expired - Fee Related
- 2000-03-22 MX MXPA01009690A patent/MXPA01009690A/es active IP Right Grant
- 2000-03-22 PT PT00919594T patent/PT1165112E/pt unknown
2003
- 2003-10-06 US US10/680,670 patent/US6923965B2/en not_active Expired - Fee Related
2006
- 2006-08-23 CY CY20061101185T patent/CY1105531T1/el unknown

Also Published As

Publication number	Publication date
CA2366604A1 (fr)	2000-10-05
EP1165112A1 (fr)	2002-01-02
ES2265928T3 (es)	2007-03-01
ATE328603T1 (de)	2006-06-15
DE60028558T2 (de)	2007-05-16
PT1165112E (pt)	2006-10-31
EP1165112B1 (fr)	2006-06-07
CY1105531T1 (el)	2010-07-28
JP2002540161A (ja)	2002-11-26
AU4025500A (en)	2000-10-16
EP1165112A4 (fr)	2002-09-25
WO2000057896A1 (fr)	2000-10-05
AU774650B2 (en)	2004-07-01
MXPA01009690A (es)	2003-06-24
US6923965B2 (en)	2005-08-02
US20040138105A1 (en)	2004-07-15
DE60028558D1 (de)	2006-07-20
US6653285B1 (en)	2003-11-25

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