DK1173471T3 - Pseudomycinanaloger - Google Patents

Pseudomycinanaloger

Info

Publication number: DK1173471T3
Authority: DK; Denmark
Prior art keywords: pseudomycin; pseudomycins; analogues; nmr; mass spectrometry
Prior art date: 1999-04-15

Application number

DK00921593T

Other languages

Danish (da)

English (en)

Inventor

Palaniappan Kulanthaivel

Matthew David Belvo

James William Martin

Thomas John Perun Jr

Douglas Joseph Zeckner

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-15

Filing date

2000-04-14

Publication date

2008-08-18

2000-04-14 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2008-08-18 Application granted granted Critical

2008-08-18 Publication of DK1173471T3 publication Critical patent/DK1173471T3/da

Links

238000005481 NMR spectroscopy Methods 0.000 abstract 2
238000004949 mass spectrometry Methods 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
NYRWZRIVFVWNTD-SGRJACMKSA-N (2s)-2-[(3s,6s,9z,12s,15s,18s,21s,24r,27s)-18-(4-aminobutyl)-15,24-bis(2-aminoethyl)-21-(carboxymethyl)-3-[(1s)-2-chloro-1-hydroxyethyl]-9-ethylidene-12-[(1s)-1-hydroxyethyl]-27-[[(3r)-3-hydroxytetradecanoyl]amino]-2,5,8,11,14,17,20,23,26-nonaoxo-1-oxa-4, Chemical compound CCCCCCCCCCC[C@@H](O)CC(=O)N[C@H]1COC(=O)[C@H]([C@H](O)CCl)NC(=O)[C@H]([C@H](O)C(O)=O)NC(=O)\C(=C\C)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CCN)NC1=O NYRWZRIVFVWNTD-SGRJACMKSA-N 0.000 abstract 1
XDPWWEOIDYYUDN-HCEIJDMSSA-N 2-[(9z)-18-(4-aminobutyl)-15,24-bis(2-aminoethyl)-21-(carboxymethyl)-3-(2-chloro-1-hydroxyethyl)-27-(3,4-dihydroxytetradecanoylamino)-9-ethylidene-12-(1-hydroxyethyl)-2,5,8,11,14,17,20,23,26-nonaoxo-1-oxa-4,7,10,13,16,19,22,25-octazacyclooctacos-6-yl]-2-h Chemical compound CCCCCCCCCCC(O)C(O)CC(=O)NC1COC(=O)C(C(O)CCl)NC(=O)C(C(O)C(O)=O)NC(=O)\C(=C\C)NC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCCCN)NC(=O)C(CC(O)=O)NC(=O)C(CCN)NC1=O XDPWWEOIDYYUDN-HCEIJDMSSA-N 0.000 abstract 1
230000000843 anti-fungal effect Effects 0.000 abstract 1
229930014626 natural product Natural products 0.000 abstract 1
108010033876 pseudomycin A Proteins 0.000 abstract 1
108010033821 pseudomycin B Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK00921593T 1999-04-15 2000-04-14 Pseudomycinanaloger DK1173471T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12944799P	1999-04-15	1999-04-15
PCT/US2000/008727 WO2000063237A2 (en)	1999-04-15	2000-04-14	Pseudomycin analogs

Publications (1)

Publication Number	Publication Date
DK1173471T3 true DK1173471T3 (da)	2008-08-18

Family

ID=22439989

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00921593T DK1173471T3 (da)	1999-04-15	2000-04-14	Pseudomycinanaloger

Country Status (17)

Country	Link
US (2)	US6630147B1 (de)
EP (1)	EP1173471B1 (de)
JP (1)	JP2002542257A (de)
CN (1)	CN1191269C (de)
AT (1)	ATE393773T1 (de)
AU (1)	AU4188700A (de)
BR (1)	BR0009731A (de)
CA (1)	CA2369136A1 (de)
DE (1)	DE60038735T2 (de)
DK (1)	DK1173471T3 (de)
EA (1)	EA004308B1 (de)
ES (1)	ES2304954T3 (de)
HU (1)	HUP0200896A3 (de)
MX (1)	MXPA01010245A (de)
NO (1)	NO20014937L (de)
PT (1)	PT1173471E (de)
WO (1)	WO2000063237A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6919188B1 (en)	1999-04-15	2005-07-19	Eli Lilly And Company	Pseudomycin production by Pseudomonas syringae
AP2028A (en) *	2000-08-18	2009-08-20	Res And Development Institute Inc	Pseudomycins Useful Against Plant Diseases.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5576298A (en) *	1992-11-30	1996-11-19	Research And Development Institute, Inc. At Montana State University	Peptides from pseudomonas syringae possessing broad-spectrum antibiotic activity
EA200101086A1 (ru) *	1999-04-15	2002-04-25	Эли Лилли Энд Компани	Антигрибковые агенты, выделенные из pseudomonas syringae
DE60035494T2 (de) *	1999-04-15	2008-03-20	Eli Lilly And Co., Indianapolis	Verfahren zur herstellung von pseudomycin aus pseudomonas syringae
CA2396513A1 (en) *	1999-12-13	2001-06-14	Yanzhi Zhang	Pseudomycin phosphate prodrugs

2000
- 2000-04-14 PT PT00921593T patent/PT1173471E/pt unknown
- 2000-04-14 AU AU41887/00A patent/AU4188700A/en not_active Abandoned
- 2000-04-14 EA EA200101090A patent/EA004308B1/ru not_active IP Right Cessation
- 2000-04-14 ES ES00921593T patent/ES2304954T3/es not_active Expired - Lifetime
- 2000-04-14 MX MXPA01010245A patent/MXPA01010245A/es active IP Right Grant
- 2000-04-14 DE DE60038735T patent/DE60038735T2/de not_active Expired - Fee Related
- 2000-04-14 CA CA002369136A patent/CA2369136A1/en not_active Abandoned
- 2000-04-14 BR BR0009731-4A patent/BR0009731A/pt not_active Application Discontinuation
- 2000-04-14 DK DK00921593T patent/DK1173471T3/da active
- 2000-04-14 JP JP2000612327A patent/JP2002542257A/ja active Pending
- 2000-04-14 HU HU0200896A patent/HUP0200896A3/hu unknown
- 2000-04-14 US US09/958,995 patent/US6630147B1/en not_active Expired - Fee Related
- 2000-04-14 CN CNB008062587A patent/CN1191269C/zh not_active Expired - Fee Related
- 2000-04-14 AT AT00921593T patent/ATE393773T1/de not_active IP Right Cessation
- 2000-04-14 WO PCT/US2000/008727 patent/WO2000063237A2/en not_active Ceased
- 2000-04-14 EP EP00921593A patent/EP1173471B1/de not_active Expired - Lifetime
2001
- 2001-10-10 NO NO20014937A patent/NO20014937L/no not_active Application Discontinuation
2003
- 2003-08-07 US US10/636,376 patent/US6793925B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU4188700A (en)	2000-11-02
ES2304954T3 (es)	2008-11-01
NO20014937L (no)	2001-12-13
CN1191269C (zh)	2005-03-02
DE60038735D1 (de)	2008-06-12
WO2000063237A3 (en)	2001-01-04
US6630147B1 (en)	2003-10-07
CN1355812A (zh)	2002-06-26
WO2000063237A2 (en)	2000-10-26
HUP0200896A2 (en)	2002-08-28
CA2369136A1 (en)	2000-10-26
EA200101090A1 (ru)	2002-06-27
EA004308B1 (ru)	2004-02-26
HUP0200896A3 (en)	2002-09-30
NO20014937D0 (no)	2001-10-10
ATE393773T1 (de)	2008-05-15
US6793925B2 (en)	2004-09-21
US20040067879A1 (en)	2004-04-08
EP1173471B1 (de)	2008-04-30
JP2002542257A (ja)	2002-12-10
BR0009731A (pt)	2002-03-05
EP1173471A2 (de)	2002-01-23
DE60038735T2 (de)	2009-07-02
MXPA01010245A (es)	2002-03-27
PT1173471E (pt)	2008-07-21

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