DK1185659T3 - DNA-vaccine-PCV - Google Patents
DNA-vaccine-PCVInfo
- Publication number
- DK1185659T3 DK1185659T3 DK00935220T DK00935220T DK1185659T3 DK 1185659 T3 DK1185659 T3 DK 1185659T3 DK 00935220 T DK00935220 T DK 00935220T DK 00935220 T DK00935220 T DK 00935220T DK 1185659 T3 DK1185659 T3 DK 1185659T3
- Authority
- DK
- Denmark
- Prior art keywords
- pcv
- sub
- orf1
- orf2
- gene
- Prior art date
Links
- 108010041986 DNA Vaccines Proteins 0.000 title 1
- 229940021995 DNA vaccine Drugs 0.000 title 1
- 101000833492 Homo sapiens Jouberin Proteins 0.000 abstract 2
- 101000651236 Homo sapiens NCK-interacting protein with SH3 domain Proteins 0.000 abstract 2
- 102100024407 Jouberin Human genes 0.000 abstract 2
- 241001504982 Pepper cryptic virus 1 Species 0.000 abstract 2
- 241001661006 Pepper cryptic virus 2 Species 0.000 abstract 2
- 101710159752 Poly(3-hydroxyalkanoate) polymerase subunit PhaE Proteins 0.000 abstract 2
- 101710130262 Probable Vpr-like protein Proteins 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- -1 cationic lipid Chemical class 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- WALUVDCNGPQPOD-UHFFFAOYSA-M 2,3-di(tetradecoxy)propyl-(2-hydroxyethyl)-dimethylazanium;bromide Chemical compound [Br-].CCCCCCCCCCCCCCOCC(C[N+](C)(C)CCO)OCCCCCCCCCCCCCC WALUVDCNGPQPOD-UHFFFAOYSA-M 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 abstract 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 abstract 1
- 229920002125 Sokalan® Polymers 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229960001631 carbomer Drugs 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Plant Pathology (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13835299P | 1999-06-10 | 1999-06-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1185659T3 true DK1185659T3 (da) | 2006-07-10 |
Family
ID=22481646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00935220T DK1185659T3 (da) | 1999-06-10 | 2000-06-08 | DNA-vaccine-PCV |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6943152B1 (pl) |
| EP (1) | EP1185659B1 (pl) |
| JP (2) | JP4824233B2 (pl) |
| KR (1) | KR100680924B1 (pl) |
| CN (1) | CN1289674C (pl) |
| AT (1) | ATE319832T1 (pl) |
| AU (1) | AU775375C (pl) |
| BR (1) | BRPI0011733B1 (pl) |
| CA (1) | CA2376523A1 (pl) |
| DE (1) | DE60026515T2 (pl) |
| DK (1) | DK1185659T3 (pl) |
| ES (1) | ES2259605T3 (pl) |
| HU (1) | HUP0201438A3 (pl) |
| MX (1) | MXPA01012722A (pl) |
| PL (1) | PL205643B1 (pl) |
| PT (1) | PT1185659E (pl) |
| TW (1) | TWI267551B (pl) |
| WO (1) | WO2000077188A2 (pl) |
| ZA (1) | ZA200110130B (pl) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6517843B1 (en) * | 1999-08-31 | 2003-02-11 | Merial | Reduction of porcine circovirus-2 viral load with inactivated PCV-2 |
| US7192594B2 (en) * | 1997-10-03 | 2007-03-20 | Merial Limited | Postweaning multisystemic wasting syndrome and porcine circovirus from pigs |
| US20040062775A1 (en) | 1997-12-05 | 2004-04-01 | Agence Francaise De Securite Sanitaire Des Aliments | Circovirus sequences associated with piglet weight loss disease (PWD) |
| FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
| FR2804028B1 (fr) * | 2000-01-21 | 2004-06-04 | Merial Sas | Vaccins adn ameliores pour animaux de rente |
| CN1309836C (zh) * | 2001-03-27 | 2007-04-11 | 萨斯喀彻温大学 | 培养环状病毒的方法 |
| US7276353B2 (en) * | 2001-12-12 | 2007-10-02 | Virginia Tech Intellectual Properties, Inc. | Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof |
| US7279166B2 (en) * | 2001-12-12 | 2007-10-09 | Virginia Tech Intellectual Properties, Inc. | Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof |
| US7371395B2 (en) * | 2003-07-24 | 2008-05-13 | Merial Limited | Vaccine formulations |
| WO2005049794A2 (en) | 2003-11-13 | 2005-06-02 | University Of Georgia Research Foundation, Inc. | Methods of characterizing infectious bursal disease virus |
| US7833707B2 (en) * | 2004-12-30 | 2010-11-16 | Boehringer Ingelheim Vetmedica, Inc. | Methods of overexpression and recovery of porcine circovirus type 2 ORF2 |
| US7700285B1 (en) | 2005-12-29 | 2010-04-20 | Boehringer Ingelheim Vetmedica, Inc. | PCV2 immunogenic compositions and methods of producing such compositions |
| HUE025537T2 (en) * | 2004-12-30 | 2016-05-30 | Boehringer Ingelheim Vetmedica Inc | PCV2-immunogenic compositions and methods for preparing such compositions |
| UA95602C2 (ru) | 2004-12-30 | 2011-08-25 | Берингер Ингельхейм Ветмедика, Инк. | Иммуногенная композиция цвс2 и способы приготовления такой композиции |
| CN1328373C (zh) * | 2005-04-07 | 2007-07-25 | 南京农业大学 | 猪ⅱ型圆环病毒重组腺病毒 |
| EP1968630B1 (en) | 2005-12-29 | 2018-01-24 | Boehringer Ingelheim Vetmedica, Inc. | Multivalent pcv2 immunogenic compositions |
| MX338626B (es) | 2005-12-29 | 2016-04-26 | Boehringer Ingelheim Vetmed | Uso de una composicion inmunogenica de pcv2 para producir los sintomas clinicos en cerdos. |
| US7862821B2 (en) | 2006-06-01 | 2011-01-04 | Merial Limited | Recombinant vaccine against bluetongue virus |
| EP2859900A1 (en) * | 2006-12-11 | 2015-04-15 | Boehringer Ingelheim Vetmedica, Inc. | Effective method of treatment of porcine circovirus and lawsonia intracellularis infections |
| JP5200223B2 (ja) * | 2006-12-15 | 2013-06-05 | ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド | Pcv2抗原によるブタの処置 |
| EP1941903A1 (en) | 2007-01-03 | 2008-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Prophylaxis and treatment of PRDC |
| EP1958644A1 (en) | 2007-02-13 | 2008-08-20 | Boehringer Ingelheim Vetmedica Gmbh | Prevention and treatment of sub-clinical pcvd |
| US7829274B2 (en) | 2007-09-04 | 2010-11-09 | Boehringer Ingelheim Vetmedica, Inc. | Reduction of concomitant infections in pigs by the use of PCV2 antigen |
| WO2009088950A2 (en) * | 2007-12-31 | 2009-07-16 | Boehringer Ingelheim Vetmedica, Inc. | Pcv2 orf2 virus like particle with foreign amino acid insertion |
| KR20100113582A (ko) * | 2008-01-23 | 2010-10-21 | 베링거잉겔하임베트메디카인코퍼레이티드 | Pcv2 마이코플라즈마 히오뉴모니에 면역원성 조성물 및 당해 조성물의 생산 방법 |
| US20110033495A1 (en) * | 2008-02-15 | 2011-02-10 | Boehringer Ingelheim Vetmedica, Inc. | Methods and compositions for reducing the impact of enteric diseases |
| AR078253A1 (es) | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
| UA107940C2 (en) * | 2009-09-10 | 2015-03-10 | Merial Ltd | The vaccine composition that includes the saponin-containing adjuvant |
| TWI442935B (zh) | 2010-12-22 | 2014-07-01 | Sbc Virbac Ltd | 豬第二型環狀病毒(Porcine Circovirus Type 2)、含彼之免疫組合物、檢測套組及其應用 |
| CA2872789C (en) | 2012-05-17 | 2019-09-03 | Zoetis Llc | Effective vaccination against porcine reproductive and respiratory syndrome (prrs) virus prior to weaning |
| ES2882374T3 (es) | 2013-05-08 | 2021-12-01 | Pharmgate Biologics Inc | Vacuna para PCV2 y micoplasma |
| EP3049106A1 (en) | 2013-09-25 | 2016-08-03 | Zoetis Services LLC | Pcv2b divergent vaccine composition and methods of use |
| US9505808B2 (en) | 2013-10-02 | 2016-11-29 | Boehringer Ingelheim Vetmedica, Inc. | PCV2 ORF2 protein variant and virus like particles composed thereof |
| CN105251000B (zh) * | 2014-09-30 | 2018-12-14 | 普莱柯生物工程股份有限公司 | 猪伪狂犬病病毒疫苗组合物及其制备方法和应用 |
| CN107683289B (zh) | 2015-01-26 | 2021-08-06 | 芝加哥大学 | IL13Rα2结合剂和其在癌症治疗中的用途 |
| HK1252427A1 (zh) | 2015-05-14 | 2019-05-24 | Boehringer Ingelheim Animal Health USA Inc. | 猪环状病毒生产方法和pcv2疫苗 |
| CN110072547B (zh) | 2016-12-14 | 2024-04-30 | 硕腾服务有限责任公司 | 断奶前对抗欧洲猪繁殖与呼吸综合征(prrs)病毒株的有效疫苗接种 |
| CN112292149A (zh) | 2018-06-11 | 2021-01-29 | 法国诗华大药厂 | 针对猪圆环病毒的疫苗接种 |
| JP7657287B2 (ja) | 2020-07-24 | 2025-04-04 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 組合せブタワクチン |
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| US4946787A (en) * | 1985-01-07 | 1990-08-07 | Syntex (U.S.A.) Inc. | N-(ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
| US5550289A (en) | 1985-01-07 | 1996-08-27 | Syntex (U.S.A.) Inc. | N-(1,(1-1)-dialkyloxy)-and N-(1,(1-1)-dialkenyloxy alk-1-yl-N-N,N-tetrasubstituted ammonium lipids and uses therefor |
| ES2052685T3 (es) * | 1987-03-17 | 1994-07-16 | Akzo Nv | Metodo para producir un adyuvante libre. |
| US5106733A (en) | 1987-06-25 | 1992-04-21 | Immunex Corporation | Bovine granulocyte-macrophage colony stimulating factor |
| CA2489769A1 (en) | 1989-03-21 | 1990-10-04 | Philip L. Felgner | Expression of exogenous polynucleotide sequences in a vertebrate |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| WO1992005255A1 (en) | 1990-09-13 | 1992-04-02 | Commonwealth Scientific And Industrial Research Organisation | Ovine cytokine genes |
| AU4662393A (en) | 1992-07-08 | 1994-01-31 | Schering Corporation | Use of gm-csf as a vaccine adjuvant |
| EP0620277A1 (en) | 1993-03-18 | 1994-10-19 | Merck & Co. Inc. | Nucleic acid pharmaceuticals |
| EP1624068A1 (en) | 1993-06-01 | 2006-02-08 | Life Technologies Inc. | Genetic immunization with cationic lipids |
| JP3626187B2 (ja) * | 1993-06-07 | 2005-03-02 | バイカル インコーポレイテッド | 遺伝子治療に適するプラスミド |
| US6015686A (en) * | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
| EP0804249A2 (en) * | 1994-03-15 | 1997-11-05 | Brown University Research Foundation | Polymeric gene delivery system |
| US5719131A (en) | 1994-12-09 | 1998-02-17 | Genzyme Corporation | Cationic amphiphiles containing dialkylamine lipophilic groups for intracellular delivery of therapeutic molecules |
| JPH11504631A (ja) | 1995-04-25 | 1999-04-27 | バイカル インコーポレイテッド | Dna/脂質複合体の単一バイアル製剤 |
| US5705385A (en) | 1995-06-07 | 1998-01-06 | Inex Pharmaceuticals Corporation | Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer |
| US6019980A (en) | 1995-06-07 | 2000-02-01 | Connaught Laboratories Limited | Nucleic acid respiratory syncytial virus vaccines |
| AU729579B2 (en) * | 1996-10-23 | 2001-02-01 | Trustees Of The University Of Pennsylvania, The | Immunotherapy and improved vaccines |
| WO1998040499A1 (en) | 1997-03-10 | 1998-09-17 | Heather Lynn Davis | Gene delivery to mucosal epithelium for immunization or therapeutic purposes |
| FR2781159B1 (fr) * | 1998-07-06 | 2000-10-06 | Merial Sas | Vaccin circovirus et parvovirus porcin |
| US6391314B1 (en) | 1997-10-03 | 2002-05-21 | Merial | Porcine circoviruses vaccines diagnostic reagents |
| UA78180C2 (uk) | 1997-10-03 | 2007-03-15 | Меріаль | Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти |
| US6165493A (en) * | 1997-10-22 | 2000-12-26 | New York Blood Center, Inc. | "Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections" |
| FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
| JP3795751B2 (ja) | 1997-12-11 | 2006-07-12 | ユニバーシティ オブ サスカッチェワン | ブタからの離乳後多全身系消耗症候群ウイルス |
| ATE338118T1 (de) * | 1997-12-12 | 2006-09-15 | Univ Western Ontario | Neues peptid, apoep1.b, zusammensetzungen und verwendungen davon |
| EP1064024A4 (en) * | 1998-03-13 | 2005-04-06 | Univ Georgia Res Found | VACCINES AGAINST CIRCOVIRUS INFECTIONS |
| AU1131200A (en) | 1998-10-23 | 2000-05-15 | Heska Corporation | Cationic lipid-mediated enhancement of nucleic acid immunization of cats |
| EP1057891A1 (en) * | 1999-06-02 | 2000-12-06 | Centrum Voor Plantenveredelings- En Reproduktieonderzoek | Use of the BNM3 transcriptional activator to control plant embryogenesis and regeneration processes |
| US6497883B1 (en) | 1999-06-10 | 2002-12-24 | Merial | Porcine circovirus recombinant poxvirus vaccine |
-
2000
- 2000-05-31 US US09/586,535 patent/US6943152B1/en not_active Expired - Lifetime
- 2000-06-08 EP EP00935220A patent/EP1185659B1/en not_active Expired - Lifetime
- 2000-06-08 MX MXPA01012722A patent/MXPA01012722A/es active IP Right Grant
- 2000-06-08 DE DE60026515T patent/DE60026515T2/de not_active Expired - Lifetime
- 2000-06-08 BR BRPI0011733A patent/BRPI0011733B1/pt not_active IP Right Cessation
- 2000-06-08 AU AU50786/00A patent/AU775375C/en not_active Expired
- 2000-06-08 PT PT00935220T patent/PT1185659E/pt unknown
- 2000-06-08 DK DK00935220T patent/DK1185659T3/da active
- 2000-06-08 JP JP2001503633A patent/JP4824233B2/ja not_active Expired - Lifetime
- 2000-06-08 WO PCT/EP2000/005611 patent/WO2000077188A2/en not_active Ceased
- 2000-06-08 AT AT00935220T patent/ATE319832T1/de active
- 2000-06-08 HU HU0201438A patent/HUP0201438A3/hu unknown
- 2000-06-08 KR KR1020017015880A patent/KR100680924B1/ko not_active Expired - Lifetime
- 2000-06-08 PL PL352199A patent/PL205643B1/pl unknown
- 2000-06-08 CN CNB008096686A patent/CN1289674C/zh not_active Expired - Lifetime
- 2000-06-08 ES ES00935220T patent/ES2259605T3/es not_active Expired - Lifetime
- 2000-06-08 CA CA002376523A patent/CA2376523A1/en not_active Abandoned
- 2000-06-12 TW TW089111424A patent/TWI267551B/zh not_active IP Right Cessation
-
2001
- 2001-12-10 ZA ZA200110130A patent/ZA200110130B/xx unknown
-
2011
- 2011-05-25 JP JP2011116460A patent/JP5410472B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT1185659E (pt) | 2006-05-31 |
| CA2376523A1 (en) | 2000-12-21 |
| PL205643B1 (pl) | 2010-05-31 |
| EP1185659B1 (en) | 2006-03-08 |
| DE60026515D1 (de) | 2006-05-04 |
| TWI267551B (en) | 2006-12-01 |
| ZA200110130B (en) | 2002-07-15 |
| HUP0201438A3 (en) | 2004-07-28 |
| KR100680924B1 (ko) | 2007-02-08 |
| MXPA01012722A (es) | 2002-07-22 |
| BRPI0011733B1 (pt) | 2017-03-28 |
| BR0011733A (pt) | 2002-07-23 |
| AU775375C (en) | 2005-02-24 |
| CN1289674C (zh) | 2006-12-13 |
| AU775375B2 (en) | 2004-07-29 |
| JP2003502303A (ja) | 2003-01-21 |
| JP5410472B2 (ja) | 2014-02-05 |
| EP1185659A2 (en) | 2002-03-13 |
| JP4824233B2 (ja) | 2011-11-30 |
| PL352199A1 (en) | 2003-08-11 |
| US6943152B1 (en) | 2005-09-13 |
| CN1376200A (zh) | 2002-10-23 |
| WO2000077188A3 (en) | 2001-05-31 |
| JP2011207897A (ja) | 2011-10-20 |
| KR20020020729A (ko) | 2002-03-15 |
| ES2259605T3 (es) | 2006-10-16 |
| HUP0201438A2 (en) | 2002-08-28 |
| WO2000077188A2 (en) | 2000-12-21 |
| ATE319832T1 (de) | 2006-03-15 |
| AU5078600A (en) | 2001-01-02 |
| DE60026515T2 (de) | 2006-11-23 |
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