DK1268775T3 - Höjt knoglemassegen af 11Q13.3 - Google Patents

Höjt knoglemassegen af 11Q13.3

Info

Publication number: DK1268775T3
Authority: DK; Denmark
Prior art keywords: methods; present; bone mass; gene; diagnosing
Prior art date: 2000-04-05

Application number

DK00941578T

Other languages

Danish (da)

English (en)

Inventor

Randall D Little

John P Carulli

Robert R Recker

Mark L Johnson

Original Assignee

Oscient Pharmaceuticals Corp

Univ Creighton

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-04-05

Filing date

2000-06-21

Publication date

2009-03-16

2000-04-05 Priority claimed from US09/544,398 external-priority patent/US6770461B1/en

2000-06-21 Application filed by Oscient Pharmaceuticals Corp, Univ Creighton filed Critical Oscient Pharmaceuticals Corp

2000-06-21 Priority claimed from PCT/US2000/016951 external-priority patent/WO2001077327A1/en

2009-03-16 Application granted granted Critical

2009-03-16 Publication of DK1268775T3 publication Critical patent/DK1268775T3/da

Links

210000000988 bone and bone Anatomy 0.000 title abstract 3
108090000623 proteins and genes Proteins 0.000 abstract 6
238000000034 method Methods 0.000 abstract 5
230000014461 bone development Effects 0.000 abstract 3
239000003155 DNA primer Substances 0.000 abstract 1
208000001132 Osteoporosis Diseases 0.000 abstract 1
238000010367 cloning Methods 0.000 abstract 1
-1 coding sequences Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000013604 expression vector Substances 0.000 abstract 1
210000001650 focal adhesion Anatomy 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
150000007523 nucleic acids Chemical class 0.000 abstract 1
239000002751 oligonucleotide probe Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
230000011664 signaling Effects 0.000 abstract 1
239000013598 vector Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Reproductive Health (AREA)
Cell Biology (AREA)
Immunology (AREA)
Addiction (AREA)
Hematology (AREA)
Neurosurgery (AREA)
Nutrition Science (AREA)
Gynecology & Obstetrics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Obesity (AREA)

DK00941578T 2000-04-05 2000-06-21 Höjt knoglemassegen af 11Q13.3 DK1268775T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US09/543,771 US6780609B1 (en)	1998-10-23	2000-04-05	High bone mass gene of 1.1q13.3
US09/544,398 US6770461B1 (en)	1998-10-23	2000-04-05	High bone mass gene of 11q13.3
PCT/US2000/016951 WO2001077327A1 (en)	2000-04-05	2000-06-21	THE HIGH BONE MASS GENE OF 11q13.3

Publications (1)

Publication Number	Publication Date
DK1268775T3 true DK1268775T3 (da)	2009-03-16

Family

ID=32851157

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00941578T DK1268775T3 (da)	2000-04-05	2000-06-21	Höjt knoglemassegen af 11Q13.3

Country Status (7)

Country	Link
US (2)	US6780609B1 (de)
EP (1)	EP1964921A3 (de)
AT (1)	ATE414772T1 (de)
DE (1)	DE60040870D1 (de)
DK (1)	DK1268775T3 (de)
ES (1)	ES2316370T3 (de)
ZA (1)	ZA200207883B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6770461B1 (en) *	1998-10-23	2004-08-03	Genome Therapeutics Corporation	High bone mass gene of 11q13.3
US7514594B2 (en) *	2001-05-11	2009-04-07	Wyeth	Transgenic animal model of bone mass modulation
WO2005071080A2 (en) *	2004-01-20	2005-08-04	Isis Pharmaceuticals, Inc.	Modulation of glucocorticoid receptor expression
EA201291181A1 (ru)	2010-05-06	2013-05-30	Новартис Аг	Композиции и способы применения терапевтических поливалентных антител против белка, родственного рецептору липопротеинов низкой плотности 6 (lrp6)
CA2798432A1 (en)	2010-05-06	2011-11-10	Novartis Ag	Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (lrp6) antibodies
KR20140091031A (ko)	2011-11-04	2014-07-18	노파르티스 아게	저밀도 지단백질-관련 단백질 6 (lrp6) - 반감기 연장제 구축물

Family Cites Families (28)

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NL154598B (nl)	1970-11-10	1977-09-15	Organon Nv	Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en)	1971-05-14	1974-06-18	Syva Corp	Enzyme amplification assay
US3939350A (en)	1974-04-29	1976-02-17	Board Of Trustees Of The Leland Stanford Junior University	Fluorescent immunoassay employing total reflection for activation
US3996345A (en)	1974-08-12	1976-12-07	Syva Company	Fluorescence quenching with immunological pairs in immunoassays
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US4366241A (en)	1980-08-07	1982-12-28	Syva Company	Concentrating zone method in heterogeneous immunoassays
CA1188246A (en)	1981-08-31	1985-06-04	Jerry L. Gregory	Immobilized microbe recycle apparatus
NZ207394A (en)	1983-03-08	1987-03-06	Commw Serum Lab Commission	Detecting or determining sequence of amino acids
US4683202A (en)	1985-03-28	1987-07-28	Cetus Corporation	Process for amplifying nucleic acid sequences
US4683195A (en)	1986-01-30	1987-07-28	Cetus Corporation	Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4973666A (en)	1987-11-06	1990-11-27	Washington Research Foundation	Peptide fragments containing HP and LP cross-links
US5283173A (en)	1990-01-24	1994-02-01	The Research Foundation Of State University Of New York	System to detect protein-protein interactions
IL103059A0 (en)	1991-09-30	1993-02-21	Boehringer Ingelheim Int	Conjugates for introducing nucleic acid into higher eucaryotic cells
US5252479A (en)	1991-11-08	1993-10-12	Research Corporation Technologies, Inc.	Safe vector for gene therapy
TW366342B (en)	1992-07-28	1999-08-11	Lilly Co Eli	The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
WO1997012903A1 (en)	1995-10-04	1997-04-10	Warner-Lambert Company	Compounds, compositions and methods for inhibiting the binding of proteins containing an sh2 domain to cognate phosphorylated proteins
US5691153A (en) *	1996-09-06	1997-11-25	Creighton University	Genetic markers to detect high bone mass
US5849902A (en)	1996-09-26	1998-12-15	Oligos Etc. Inc.	Three component chimeric antisense oligonucleotides
US6555654B1 (en)	1997-04-15	2003-04-29	The Wellcome Trust Limited As Trustee For The Wellcome Trust	LDL-receptor
EP0988379B1 (de)	1997-04-15	2007-04-11	The Wellcome Trust Limited as Trustee to the Wellcome Trust	Ldl-rezeptor
BE1011331A6 (fr)	1997-08-20	1999-07-06	Univ Catholique De Louvain Hal	Polypeptide associe au peroxysome, sequence nucleotidique encodant ledit polypeptide et leur utilisation dans le diagnostic et/ou le traitement de maladies ou de lesions pulmonaires.
FR2768747B1 (fr)	1997-09-19	2000-12-01	Pasteur Institut	Acides nucleiques, cellules recombinantes, et procede de preparation de compositions immunogenes
EP1064289A1 (de)	1998-03-18	2001-01-03	Ariad Pharmaceuticals, Inc.	Heterozyclische inhibitoren von signal-transduction, sie enthaltende zusammensetzungen
EP1285002B1 (de) *	2000-05-26	2007-07-18	Oscient Pharmaceuticals Corporation	Regulation des lipidniveaus über die gene zmax1 oder hbm
US7416849B2 (en) *	2001-05-11	2008-08-26	Oscient Pharmaceuticals Corporation	HBM variants that modulate bone mass and lipid levels
US8637506B2 (en) *	2003-09-22	2014-01-28	Enzo Biochem, Inc.	Compositions and methods for bone formation and remodeling
KR102371587B1 (ko)	2015-05-22	2022-03-07	현대자동차주식회사	횡단보도 인식 결과를 이용한 안내 정보 제공 장치 및 방법

2000
- 2000-04-05 US US09/543,771 patent/US6780609B1/en not_active Expired - Fee Related
- 2000-06-21 DE DE60040870T patent/DE60040870D1/de not_active Expired - Lifetime
- 2000-06-21 EP EP08006373A patent/EP1964921A3/de not_active Withdrawn
- 2000-06-21 DK DK00941578T patent/DK1268775T3/da active
- 2000-06-21 AT AT00941578T patent/ATE414772T1/de not_active IP Right Cessation
- 2000-06-21 ES ES00941578T patent/ES2316370T3/es not_active Expired - Lifetime
2002
- 2002-10-01 ZA ZA200207883A patent/ZA200207883B/xx unknown
2004
- 2004-04-29 US US10/834,377 patent/US20050142617A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ATE414772T1 (de)	2008-12-15
ZA200207883B (en)	2004-01-27
EP1964921A3 (de)	2008-12-03
US6780609B1 (en)	2004-08-24
ES2316370T3 (es)	2009-04-16
DE60040870D1 (de)	2009-01-02
US20050142617A1 (en)	2005-06-30
EP1964921A2 (de)	2008-09-03

Publication	Publication Date	Title
MXPA03010077A (es)	2004-04-02	Abonadora de siembra a voleo con deflector movible.
WO2002092764A3 (en)	2003-12-24	Transgenic animal model of bone mass modulation
CY1108998T1 (el)	2014-07-02	Πρωτεϊνες που δεσμευονται με οστεοπροτεγερινη και υποδοχεις
FI961251A0 (fi)	1996-03-18	Ihmisten metabotrooppiset glutamaattireseptorialatyypit(HMR4, HMR6, HMR7)ja niihin liittyvät DNA-yhdisteet
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ATE552340T1 (de)	2012-04-15	Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln
EA199900939A1 (ru)	2000-08-28	Остеопротегерин-связывающие белки и рецепторы
ATE378407T1 (de)	2007-11-15	Morphogene protein-spezifische zelloberflächenrezeptoren und ihre verwendungen
DK1124846T3 (da)	2009-10-26	Nukleotid- og proteinsekvenser af Nogo-gener og derpå baserede fremgangsmåder
MXPA02009791A (es)	2004-09-06	El gen de alta masa osea de 11q13.3.
CA2192940A1 (en)	1995-12-28	Nucleotide sequences of pestivirus strains, polypeptides encoded by these sequences and use thereof for diagnosis and prevention of pestivirus infections
ATE304052T1 (de)	2005-09-15	Humane checkpointkinase, hcds1, zusammensetzungen und verfahren
ATE329026T1 (de)	2006-06-15	In knorpelgeweben stark exprimiertes gen
DK1285002T3 (da)	2007-10-29	Regulering af lipidniveauer ved hjælp af ZMAX1- eller HBM-genet
ZA200207883B (en)	2004-01-27	The High Bone Mass Gene of 11Q13.3.
DE69826493D1 (de)	2004-10-28	Ikk-alpha proteine, nukleinsäuren und verfahren
ATE255638T1 (de)	2003-12-15	Nukleotidsequenzen und gegen cycloheximid resistente proteine
EA200000845A1 (ru)	2001-08-27	Ген, кодирующий новый маркер рака
ATE483019T1 (de)	2010-10-15	Aus einem neuroblastom in stufe 4s isoliertenukleinsäuren
DK0778347T3 (da)	2006-09-25	Protein med formodede helicase- og ATPase-egenskaber, som binder ATP og nukleinsyre
Gibson et al.	1993	Non-muscle and smooth muscle myosin light chain kinases: no end in sight
BR9811501A (pt)	2000-09-19	Sequência de nucleotìdeos do gene nucleocapsìdeo de vìrus oropouche
DE69813837D1 (de)	2003-05-28	Gen des familiären mittelmeerfiebers