DK1282084T3 - Fremgangsmåde til fremstilling af pyrimidonderivater med antifungal aktivitet - Google Patents
Fremgangsmåde til fremstilling af pyrimidonderivater med antifungal aktivitetInfo
- Publication number
- DK1282084T3 DK1282084T3 DK01909840T DK01909840T DK1282084T3 DK 1282084 T3 DK1282084 T3 DK 1282084T3 DK 01909840 T DK01909840 T DK 01909840T DK 01909840 T DK01909840 T DK 01909840T DK 1282084 T3 DK1282084 T3 DK 1282084T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- antifungal activity
- pyrimidone derivatives
- pyrimidone
- derivatives
- Prior art date
Links
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 150000008318 pyrimidones Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200000625A ES2159488B1 (es) | 2000-03-07 | 2000-03-07 | Procedimiento para la preparacion de derivados de pirimidona con actividad antifungica. |
| PCT/ES2001/000081 WO2001066519A2 (es) | 2000-03-07 | 2001-03-05 | Procedimiento para la preparacion de derivados de pirimidona con actividad antifungica |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1282084T3 true DK1282084T3 (da) | 2004-02-02 |
Family
ID=8492714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01909840T DK1282084T3 (da) | 2000-03-07 | 2001-03-05 | Fremgangsmåde til fremstilling af pyrimidonderivater med antifungal aktivitet |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6653475B2 (da) |
| EP (1) | EP1282084B9 (da) |
| JP (1) | JP4772248B2 (da) |
| KR (1) | KR100735583B1 (da) |
| AR (1) | AR027607A1 (da) |
| AT (1) | ATE250256T1 (da) |
| AU (1) | AU2001237447A1 (da) |
| BR (1) | BRPI0108990B8 (da) |
| CA (1) | CA2402390C (da) |
| DE (1) | DE60100810T2 (da) |
| DK (1) | DK1282084T3 (da) |
| ES (2) | ES2159488B1 (da) |
| HK (1) | HK1052244B (da) |
| MX (1) | MXPA02008556A (da) |
| NO (1) | NO323314B1 (da) |
| PT (1) | PT1282084E (da) |
| WO (1) | WO2001066519A2 (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7230000B1 (en) | 1999-10-27 | 2007-06-12 | Cytokinetics, Incorporated | Methods and compositions utilizing quinazolinones |
| US6545004B1 (en) | 1999-10-27 | 2003-04-08 | Cytokinetics, Inc. | Methods and compositions utilizing quinazolinones |
| EP1477481B1 (en) * | 2002-01-28 | 2009-07-22 | Ube Industries, Ltd. | Process for producing quinazolin-4-one derivative |
| US7009049B2 (en) | 2002-02-15 | 2006-03-07 | Cytokinetics, Inc. | Syntheses of quinazolinones |
| AU2003270015A1 (en) | 2002-05-09 | 2003-12-02 | Cytokinetics, Inc. | Compounds, compositions, and methods |
| US7166595B2 (en) | 2002-05-09 | 2007-01-23 | Cytokinetics, Inc. | Compounds, methods and compositions |
| WO2003103575A2 (en) | 2002-05-23 | 2003-12-18 | Cytokinetics, Inc. | Compounds, compositions, and methods |
| CA2489367A1 (en) | 2002-06-14 | 2003-12-24 | Cytokinetics, Inc. | Compounds, compositions, and methods |
| WO2004009036A2 (en) | 2002-07-23 | 2004-01-29 | Cytokinetics, Inc. | Compounds compositions and methods |
| WO2004034972A2 (en) | 2002-09-30 | 2004-04-29 | Cytokinetics, Inc. | Compounds, compositions, and methods |
| EP1692112A4 (en) | 2003-12-08 | 2008-09-24 | Cytokinetics Inc | COMPOUNDS, COMPOSITIONS, AND METHODS |
| JP5055263B2 (ja) | 2005-03-30 | 2012-10-24 | ダエウン ファーマシューティカル カンパニー リミテッド | 抗真菌性トリアゾール誘導体 |
| EP2049504A4 (en) * | 2006-08-07 | 2010-09-22 | Stiefel Laboratories | ANTIFUNGAL CRYSTALLINE COMPOUNDS |
| EP2009009A1 (en) * | 2007-06-26 | 2008-12-31 | Palau Pharma, S.A. | Crystalline antifungal compounds |
| EP1887004A1 (en) * | 2006-08-07 | 2008-02-13 | Palau Pharma, S.A. | Crystalline forms of (1R,2R)-7-Chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one |
| TWI395728B (zh) | 2006-12-06 | 2013-05-11 | Du Pont | 製備２-胺基-５-氰基苯甲酸衍生物之方法 |
| TWI415827B (zh) | 2006-12-21 | 2013-11-21 | Du Pont | 製備２-胺基-５-氰基苯甲酸衍生物之方法 |
| EP2257555B1 (en) | 2008-03-03 | 2012-07-04 | National Chemical Laboratory | Thieno[2,3-d]-pyrimidine-4(3h)-one compounds with antifungal properties and process thereof |
| SE532624C2 (sv) * | 2008-06-19 | 2010-03-09 | Andritz Technology And Asset Management Gmbh | Kylning av en cellulosamassabana |
| WO2012123952A1 (en) * | 2011-03-15 | 2012-09-20 | Fdc Limited | Enantiomers of fluconazole analogues containing thieno-[2,3-d]pyrimidin-4(3h)-one moiety as antifungal agents |
| CN106588889B (zh) * | 2016-11-25 | 2019-01-22 | 江苏恒盛药业有限公司 | 一种伏立康唑的制备方法 |
| CN111018839B (zh) * | 2019-12-02 | 2022-12-23 | 中国人民解放军第二军医大学 | 三氮唑醇类衍生物及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8819308D0 (en) * | 1988-08-13 | 1988-09-14 | Pfizer Ltd | Triazole antifungal agents |
| TW218017B (da) * | 1992-04-28 | 1993-12-21 | Takeda Pharm Industry Co Ltd | |
| MX9702382A (es) * | 1995-08-02 | 1998-02-28 | Uriach & Cia Sa J | Nuevos derivados de pirimidona con actividad antifungica. |
-
2000
- 2000-03-07 ES ES200000625A patent/ES2159488B1/es not_active Expired - Fee Related
-
2001
- 2001-03-02 AR ARP010101022A patent/AR027607A1/es active IP Right Grant
- 2001-03-05 MX MXPA02008556A patent/MXPA02008556A/es active IP Right Grant
- 2001-03-05 HK HK03104472.6A patent/HK1052244B/en not_active IP Right Cessation
- 2001-03-05 EP EP01909840A patent/EP1282084B9/en not_active Expired - Lifetime
- 2001-03-05 JP JP2001565337A patent/JP4772248B2/ja not_active Expired - Lifetime
- 2001-03-05 US US10/221,099 patent/US6653475B2/en not_active Expired - Lifetime
- 2001-03-05 ES ES01909840T patent/ES2207605T3/es not_active Expired - Lifetime
- 2001-03-05 KR KR1020027011732A patent/KR100735583B1/ko not_active Expired - Lifetime
- 2001-03-05 DK DK01909840T patent/DK1282084T3/da active
- 2001-03-05 BR BRPI0108990A patent/BRPI0108990B8/pt not_active IP Right Cessation
- 2001-03-05 PT PT01909840T patent/PT1282084E/pt unknown
- 2001-03-05 AT AT01909840T patent/ATE250256T1/de active
- 2001-03-05 WO PCT/ES2001/000081 patent/WO2001066519A2/es not_active Ceased
- 2001-03-05 AU AU2001237447A patent/AU2001237447A1/en not_active Abandoned
- 2001-03-05 CA CA002402390A patent/CA2402390C/en not_active Expired - Lifetime
- 2001-03-05 DE DE60100810T patent/DE60100810T2/de not_active Expired - Lifetime
-
2002
- 2002-09-06 NO NO20024256A patent/NO323314B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HK1052244A1 (en) | 2003-09-05 |
| KR100735583B1 (ko) | 2007-07-04 |
| US6653475B2 (en) | 2003-11-25 |
| EP1282084B9 (en) | 2005-03-02 |
| ATE250256T1 (de) | 2003-10-15 |
| AR027607A1 (es) | 2003-04-02 |
| CA2402390A1 (en) | 2001-09-13 |
| NO20024256D0 (no) | 2002-09-06 |
| WO2001066519A2 (es) | 2001-09-13 |
| BR0108990B1 (pt) | 2014-03-25 |
| EP1282084B1 (en) | 2003-09-17 |
| CA2402390C (en) | 2009-09-15 |
| AU2001237447A1 (en) | 2001-09-17 |
| ES2207605T3 (es) | 2004-06-01 |
| NO323314B1 (no) | 2007-03-12 |
| DE60100810D1 (de) | 2003-10-23 |
| DE60100810T2 (de) | 2004-07-01 |
| ES2159488A1 (es) | 2001-10-01 |
| BR0108990A (pt) | 2003-12-30 |
| JP2004500391A (ja) | 2004-01-08 |
| WO2001066519A3 (es) | 2002-01-31 |
| EP1282084A2 (en) | 2003-02-05 |
| JP4772248B2 (ja) | 2011-09-14 |
| BRPI0108990B8 (pt) | 2021-05-25 |
| ES2159488B1 (es) | 2002-04-16 |
| KR20020075809A (ko) | 2002-10-05 |
| NO20024256L (no) | 2002-09-06 |
| PT1282084E (pt) | 2004-02-27 |
| HK1052244B (en) | 2003-12-19 |
| US20030064986A1 (en) | 2003-04-03 |
| MXPA02008556A (es) | 2003-02-24 |
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