DK1299541T3 - Fremgangsmåde til udvinding og anvendelse af nye humane defensiner som biologisk aktive proteiner til behandling af infektioner og andre sygdomme - Google Patents

Fremgangsmåde til udvinding og anvendelse af nye humane defensiner som biologisk aktive proteiner til behandling af infektioner og andre sygdomme

Info

Publication number: DK1299541T3
Authority: DK; Denmark
Prior art keywords: fragments; derivatives; diseases; extraction; biologically active
Prior art date: 2000-07-11

Application number

DK01969365T

Other languages

English (en)

Inventor

Wolf-Georg Forssmann

Jose-Ramon Conejo-Garcia

Knut Adermann

Original Assignee

Ipf Pharmaceuticals Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-11

Filing date

2001-07-11

Publication date

2008-01-21

2001-07-11 Application filed by Ipf Pharmaceuticals Gmbh filed Critical Ipf Pharmaceuticals Gmbh

2008-01-21 Application granted granted Critical

2008-01-21 Publication of DK1299541T3 publication Critical patent/DK1299541T3/da

Links

102000000541 Defensins Human genes 0.000 title abstract 2
108010002069 Defensins Proteins 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
201000010099 disease Diseases 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
238000000605 extraction Methods 0.000 title 1
208000015181 infectious disease Diseases 0.000 title 1
102000004169 proteins and genes Human genes 0.000 title 1
108090000623 proteins and genes Proteins 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 4
239000012634 fragment Substances 0.000 abstract 3
150000001413 amino acids Chemical class 0.000 abstract 2
150000007523 nucleic acids Chemical class 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
241000588724 Escherichia coli Species 0.000 abstract 1
240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
235000014680 Saccharomyces cerevisiae Nutrition 0.000 abstract 1
241000191940 Staphylococcus Species 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
239000003433 contraceptive agent Substances 0.000 abstract 1
230000002254 contraceptive effect Effects 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
238000009792 diffusion process Methods 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000010534 mechanism of action Effects 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Pulmonology (AREA)
Gastroenterology & Hepatology (AREA)
Urology & Nephrology (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gynecology & Obstetrics (AREA)
Zoology (AREA)
Oncology (AREA)
Pregnancy & Childbirth (AREA)
Otolaryngology (AREA)
Communicable Diseases (AREA)
Dermatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK01969365T 2000-07-11 2001-07-11 Fremgangsmåde til udvinding og anvendelse af nye humane defensiner som biologisk aktive proteiner til behandling af infektioner og andre sygdomme DK1299541T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10033505		2000-07-11
PCT/EP2001/007973 WO2002004487A2 (de)	2000-07-11	2001-07-11	Verfahren zur gewinnung und anwendung neuer humaner defensine als biologisch aktive eiweisstoffe zur behandlung von infektionen und anderen erkrankungen

Publications (1)

Publication Number	Publication Date
DK1299541T3 true DK1299541T3 (da)	2008-01-21

Family

ID=7648436

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01969365T DK1299541T3 (da)	2000-07-11	2001-07-11	Fremgangsmåde til udvinding og anvendelse af nye humane defensiner som biologisk aktive proteiner til behandling af infektioner og andre sygdomme

Country Status (11)

Country	Link
US (2)	US20040116652A1 (da)
EP (2)	EP1887015A3 (da)
JP (1)	JP2004504017A (da)
AT (1)	ATE373091T1 (da)
AU (1)	AU2001289641A1 (da)
CA (1)	CA2427066A1 (da)
DE (1)	DE50113010D1 (da)
DK (1)	DK1299541T3 (da)
ES (1)	ES2197840T3 (da)
PT (1)	PT1299541E (da)
WO (1)	WO2002004487A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6576755B1 (en)	1997-09-10	2003-06-10	Zymogenetics, Inc.	Beta-defensins
EP1878796A3 (en) *	1999-11-30	2008-01-23	Genentech, Inc.	Compositions and methods for the treatment of immune related diseases
AU2001275208A1 (en) *	2000-06-01	2001-12-11	University Of Iowa Research Foundation	Human beta-defensin-3 (hbd-3), a highly cationic beta-defensin antimicrobial peptide
WO2002040512A2 (de) *	2000-11-14	2002-05-23	Ipf Pharmaceuticals Gmbh	Humanes beta-defensin-3
JP2006514106A (ja) *	2002-12-19	2006-04-27	ヒルマン，イチャク	抗菌ペプチド阻害剤による疾患治療
GB0300718D0 (en) *	2003-01-13	2003-02-12	Ares Trading Sa	Proteins
FR2879203A1 (fr) *	2004-12-09	2006-06-16	Univ Rennes I Etablissement Pu	Peptides antimicrobiens, polypeptides comprenant lesdits peptides, procedes pour les preparer, genes codant pour lesdits peptides, vecteurs, organismes transformes et compositions les contenant
US8202835B2 (en)	2005-06-17	2012-06-19	Yitzchak Hillman	Disease treatment via antimicrobial peptides or their inhibitors
US9044438B2 (en)	2005-06-17	2015-06-02	Yitzchak Hillman	Disease treatment via antimicrobial peptides or their inhibitors
GB0514482D0 (en) *	2005-07-14	2005-08-17	Ares Trading Sa	Protein
CN102198264B (zh) *	2010-03-23	2013-10-09	中国科学院上海生命科学研究院	大鼠附睾特异抗菌肽β-防御素15及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2303421C (en) *	1997-09-10	2005-07-12	Zymogenetics, Inc.	Beta-defensins
US6783961B1 (en) *	1999-02-26	2004-08-31	Genset S.A.	Expressed sequence tags and encoded human proteins
WO2000046245A2 (de) *	1999-02-01	2000-08-10	Schering Aktiengesellschaft	Humane antibiotische proteine
US20040072777A1 (en) *	2000-01-05	2004-04-15	Otto Froelich	Epididymal antimicrobial peptides

2001
- 2001-07-11 EP EP07116049A patent/EP1887015A3/de not_active Withdrawn
- 2001-07-11 EP EP01969365A patent/EP1299541B1/de not_active Expired - Lifetime
- 2001-07-11 ES ES01969365T patent/ES2197840T3/es not_active Expired - Lifetime
- 2001-07-11 DK DK01969365T patent/DK1299541T3/da active
- 2001-07-11 US US10/332,765 patent/US20040116652A1/en not_active Abandoned
- 2001-07-11 PT PT01969365T patent/PT1299541E/pt unknown
- 2001-07-11 JP JP2002509350A patent/JP2004504017A/ja not_active Abandoned
- 2001-07-11 WO PCT/EP2001/007973 patent/WO2002004487A2/de not_active Ceased
- 2001-07-11 DE DE50113010T patent/DE50113010D1/de not_active Expired - Fee Related
- 2001-07-11 AT AT01969365T patent/ATE373091T1/de not_active IP Right Cessation
- 2001-07-11 AU AU2001289641A patent/AU2001289641A1/en not_active Abandoned
- 2001-07-11 CA CA002427066A patent/CA2427066A1/en not_active Abandoned
2007
- 2007-04-27 US US11/790,770 patent/US20090124541A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU2001289641A1 (en)	2002-01-21
WO2002004487A2 (de)	2002-01-17
US20090124541A1 (en)	2009-05-14
EP1299541B1 (de)	2007-09-12
US20040116652A1 (en)	2004-06-17
WO2002004487A3 (de)	2002-09-19
EP1887015A2 (de)	2008-02-13
DE50113010D1 (de)	2007-10-25
ES2197840T3 (es)	2008-03-16
ATE373091T1 (de)	2007-09-15
CA2427066A1 (en)	2003-02-24
ES2197840T1 (es)	2004-01-16
EP1887015A3 (de)	2008-05-07
PT1299541E (pt)	2007-10-01
EP1299541A2 (de)	2003-04-09
JP2004504017A (ja)	2004-02-12

Publication	Publication Date	Title
Charpentier et al.	1998	Structure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics
KR100891157B1 (ko)	2009-04-07	짧은 생물활성 펩티드 및 그것들의 사용 방법
Conlon et al.	2003	Isolation of peptides of the brevinin‐1 family with potent candidacidal activity from the skin secretions of the frog Rana boylii
DK1299541T3 (da)	2008-01-21	Fremgangsmåde til udvinding og anvendelse af nye humane defensiner som biologisk aktive proteiner til behandling af infektioner og andre sygdomme
Casciaro et al.	2020	The Potential of frog skin peptides for anti-Infective therapies: the Case of Esculentin-1a (1-21) NH2
NO20045521L (no)	2004-12-17	Diarylureaderivater anvendelige for behandling av proteinkinaseavhengige sykdommer
CY1107051T1 (el)	2012-10-24	Αντι-διηθητικα και αντι-αγγειογενετικα θραυσματα ουροκινασης και η χρηση τους
DE60138558D1 (de)	2009-06-10	Peptid aus hsp70 welches nk zellaktivtät stimuliert und seine verwendung
ATE349538T1 (de)	2007-01-15	Collectin-komplement aktivierende proteinchimären
ATE427116T1 (de)	2009-04-15	Behandlung von bakteriellen infektionen
TR201815301T4 (tr)	2018-11-21	Antimikrobiyal peptit ve bunun kullanımları.
Chen et al.	2017	Purification and characterization of an antibacterial and anti-inflammatory polypeptide from Arca subcrenata
Beaumont et al.	2012	LL-37: an immunomodulatory antimicrobial host defence peptide
Kim et al.	2007	Purification and characterization of antimicrobial peptides from the skin secretion of Rana dybowskii
US20150218233A1 (en)	2015-08-06	Synthetic pntx(19) peptide, pharmaceutical compositions and use
CN117510611A (zh)	2024-02-06	一种抗菌肽及其制备方法和应用
ES2002915A6 (es)	1988-10-01	Un procedimiento para la preparacion de un peptido de veneno de serpiente que detiene el crecimiento.
KR20220044947A (ko)	2022-04-12	진균 감염의 치료를 위한 조성물 및 방법(compositions and methods for treatment of fungal infections)
BRPI0418359A (pt)	2007-05-08	método simplificado para recuperar quitosana a partir de suas soluções ácidas
WO2004046166A2 (en)	2004-06-03	Modified alpha-msh peptides and derivatives thereof
Schröder et al.	2006	Antimicrobial peptides in skin disease
AR013886A1 (es)	2001-01-31	Proteinas utiles para tratar la obesidad y condiciones asociadas con la obesidad; composiciones farmaceuticas formuladas con dichas proteinas;compuestos polinucleoticos de dna que codifican dichas proteinas y procedimiento para pepararlas
KR100488038B1 (ko)	2005-05-09	기관 보호 활성을 지닌 신규한 신체 보호 화합물 펩티드염, 이의 제조 방법 및 치료에서의 이의 용도
CN116942554A (zh)	2023-10-27	一种控油祛痘精华液及其制备方法
KR101384577B1 (ko)	2014-04-11	황다랑어 유래의 새로운 항미생물성 펩타이드 및 이의 용도