ATE349538T1 - Collectin-komplement aktivierende proteinchimären - Google Patents

Collectin-komplement aktivierende proteinchimären

Info

Publication number
ATE349538T1
ATE349538T1 AT03794818T AT03794818T ATE349538T1 AT E349538 T1 ATE349538 T1 AT E349538T1 AT 03794818 T AT03794818 T AT 03794818T AT 03794818 T AT03794818 T AT 03794818T AT E349538 T1 ATE349538 T1 AT E349538T1
Authority
AT
Austria
Prior art keywords
fusion protein
complement
collectin
activating
protein
Prior art date
Application number
AT03794818T
Other languages
English (en)
Inventor
Leif Kongerslev
Dietmar Weilguny
Finn Matthiesen
Original Assignee
Natlmmune As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natlmmune As filed Critical Natlmmune As
Application granted granted Critical
Publication of ATE349538T1 publication Critical patent/ATE349538T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT03794818T 2002-09-10 2003-09-10 Collectin-komplement aktivierende proteinchimären ATE349538T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200201328 2002-09-10

Publications (1)

Publication Number Publication Date
ATE349538T1 true ATE349538T1 (de) 2007-01-15

Family

ID=31984965

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03794818T ATE349538T1 (de) 2002-09-10 2003-09-10 Collectin-komplement aktivierende proteinchimären

Country Status (11)

Country Link
US (1) US20060188963A1 (de)
EP (1) EP1539964B1 (de)
JP (1) JP2005537807A (de)
CN (1) CN1694961A (de)
AT (1) ATE349538T1 (de)
AU (1) AU2003260286A1 (de)
DE (1) DE60310736T2 (de)
DK (1) DK1539964T3 (de)
ES (1) ES2279981T3 (de)
PT (1) PT1539964E (de)
WO (1) WO2004024925A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0522113D0 (en) * 2005-10-28 2005-12-07 Ares Trading Sa vWFA-domain containing proteins
EP3321277B1 (de) 2007-07-10 2019-09-18 Apogenix AG Collectin-fusionsproteine der tnf-superfamilie
EP2225269A2 (de) * 2007-11-09 2010-09-08 Anaphore, Inc. Fusionsproteine von mannosebindenden lektinen zur behandlung von krankheiten
US20100331240A1 (en) * 2008-01-18 2010-12-30 The General Hospital Corporation Methods for prevention and treatment of infections with supraphysiological doses of mannan-binding lectin (mbl) and ficolin-mbl fusion proteins
CN102325882A (zh) * 2008-12-22 2012-01-18 国立大学法人北海道大学 具有三螺旋结构的蛋白质物质及其制造方法
JP5844158B2 (ja) * 2009-01-09 2016-01-13 アポゲニクス ゲゼルシャフト ミット ベシュレンクテル ハフツングＡｐｏｇｅｎｉｘ ＧｍｂＨ 三量体形成融合タンパク質
JP5752052B2 (ja) * 2009-01-28 2015-07-22 コリア リサーチ インスティテュート オブ バイオサイエンス アンド バイオテクノロジー Ｃｄ９３またはその可溶性断片の用途
EP3395828A1 (de) * 2009-07-17 2018-10-31 Rigshospitalet Inhibitoren der komplementären aktivierung
AU2011207626B2 (en) 2010-01-19 2015-06-18 President And Fellows Of Harvard College Engineered opsonin for pathogen detection and treatment
WO2011108281A1 (ja) * 2010-03-04 2011-09-09 扶桑薬品工業株式会社 虚血性疾患亢進作用を有するポリペプチド
EP3815708A1 (de) 2010-03-05 2021-05-05 Omeros Corporation Chimäre inhibitormoleküle mit komplementaktivierung
EP3081937B1 (de) 2011-07-18 2019-11-13 President and Fellows of Harvard College Manipulierte moleküle zum targeting von mikroben und verwendungen davon
WO2013130875A1 (en) 2012-02-29 2013-09-06 President And Fellows Of Harvard College Rapid antibiotic susceptibility testing
US10551379B2 (en) 2013-03-15 2020-02-04 President And Fellows Of Harvard College Methods and compositions for improving detection and/or capture of a target entity
EP3848045A1 (de) 2013-05-21 2021-07-14 President and Fellows of Harvard College Manipulierte hämbindende zusammensetzungen und verwendungen davon
EP3912986B1 (de) 2013-12-18 2023-12-13 President and Fellows of Harvard College Crp-erfassung/-detektion von bakterien
JP2014218510A (ja) * 2014-08-11 2014-11-20 アポゲニクスゲゼルシャフト ミット ベシュレンクテルハフツングＡｐｏｇｅｎｉｘ ＧｍｂＨ 三量体形成融合タンパク質
CN108289928B (zh) 2015-08-06 2024-09-17 哈佛大学校长及研究员协会 改进的微生物-结合分子和其用途
JP2016210791A (ja) * 2016-08-03 2016-12-15 アポゲニクス アーゲー 三量体形成融合タンパク質
SG10201802979VA (en) * 2018-04-10 2019-11-28 Kah Meng Lim Immunological extract and method of production
WO2022079308A1 (en) * 2020-10-16 2022-04-21 Institut Pasteur Chimeric constructs useful in vaccination and cancer therapy
CN113307857B (zh) * 2021-01-14 2022-11-01 艾时斌 从表皮生长因子、凝集素和Tat蛋白衍生的支架蛋白
EP4412634A4 (de) * 2021-10-07 2025-08-20 Omeros Corp Gezielte katalytische komplementaktivierende moleküle und verfahren zur verwendung davon
CN114344453A (zh) * 2022-01-18 2022-04-15 华南师范大学 一种罗非鱼cl-k1在制备预防和/或治疗罗非鱼病害的药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1106846C (zh) * 1997-08-21 2003-04-30 宝酒造株式会社 抗癌症剂
JPH11206378A (ja) * 1998-01-23 1999-08-03 Fuso Pharmaceutical Industries Ltd 組換えヒトマンナン結合タンパク質およびその製造方法
US7049099B2 (en) * 1998-01-23 2006-05-23 Fuso Pharmaceutical Industries, Ltd. Recombinant human mannan-binding proteins and producing method of the same
US6337193B1 (en) * 1998-11-24 2002-01-08 Aptagen, Inc. Expression of manose-binding protein in methylotrophic yeast
EP1402897B1 (de) * 1999-05-14 2006-08-16 Steffen Thiel Neue Indikationen für Mannan-binding Lectin (MBL) zur Behandlung von immungeschwächten Patienten
CA2391402A1 (en) * 1999-12-02 2001-06-07 Jens Christian Jensenius Masp-3, a complement-fixing enzyme, and uses for it
DE60139072D1 (de) * 2000-07-13 2009-08-06 Helion Biotech Aps Masp-2, ein komplement fixierendes enzym, und dessen verwendungen
US20050137126A1 (en) * 2003-04-09 2005-06-23 Natlmmune A/S Treatment of SARS in individuals

Also Published As

Publication number Publication date
DE60310736D1 (de) 2007-02-08
DE60310736T2 (de) 2007-10-11
WO2004024925A8 (en) 2004-05-21
AU2003260286A1 (en) 2004-04-30
PT1539964E (pt) 2007-04-30
JP2005537807A (ja) 2005-12-15
CN1694961A (zh) 2005-11-09
WO2004024925A2 (en) 2004-03-25
US20060188963A1 (en) 2006-08-24
EP1539964B1 (de) 2006-12-27
WO2004024925A3 (en) 2004-06-24
EP1539964A2 (de) 2005-06-15
DK1539964T3 (da) 2007-05-07
ES2279981T3 (es) 2007-09-01

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