ATE349538T1 - Collectin-komplement aktivierende proteinchimären - Google Patents

Collectin-komplement aktivierende proteinchimären

Info

Publication number
ATE349538T1
ATE349538T1 AT03794818T AT03794818T ATE349538T1 AT E349538 T1 ATE349538 T1 AT E349538T1 AT 03794818 T AT03794818 T AT 03794818T AT 03794818 T AT03794818 T AT 03794818T AT E349538 T1 ATE349538 T1 AT E349538T1
Authority
AT
Austria
Prior art keywords
fusion protein
complement
collectin
activating
protein
Prior art date
Application number
AT03794818T
Other languages
English (en)
Inventor
Leif Kongerslev
Dietmar Weilguny
Finn Matthiesen
Original Assignee
Natlmmune As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natlmmune As filed Critical Natlmmune As
Application granted granted Critical
Publication of ATE349538T1 publication Critical patent/ATE349538T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT03794818T 2002-09-10 2003-09-10 Collectin-komplement aktivierende proteinchimären ATE349538T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200201328 2002-09-10

Publications (1)

Publication Number Publication Date
ATE349538T1 true ATE349538T1 (de) 2007-01-15

Family

ID=31984965

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03794818T ATE349538T1 (de) 2002-09-10 2003-09-10 Collectin-komplement aktivierende proteinchimären

Country Status (11)

Country Link
US (1) US20060188963A1 (de)
EP (1) EP1539964B1 (de)
JP (1) JP2005537807A (de)
CN (1) CN1694961A (de)
AT (1) ATE349538T1 (de)
AU (1) AU2003260286A1 (de)
DE (1) DE60310736T2 (de)
DK (1) DK1539964T3 (de)
ES (1) ES2279981T3 (de)
PT (1) PT1539964E (de)
WO (1) WO2004024925A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0522113D0 (en) * 2005-10-28 2005-12-07 Ares Trading Sa vWFA-domain containing proteins
ES2657801T3 (es) 2007-07-10 2018-03-06 Apogenix Ag Proteínas de fusión de colectina de la superfamilia de TNF
WO2009062195A2 (en) * 2007-11-09 2009-05-14 Anaphore, Inc. Fusion proteins of mannose binding lectins for treatment of disease
US20100331240A1 (en) * 2008-01-18 2010-12-30 The General Hospital Corporation Methods for prevention and treatment of infections with supraphysiological doses of mannan-binding lectin (mbl) and ficolin-mbl fusion proteins
CN106243229B (zh) * 2008-12-22 2019-09-06 国立大学法人北海道大学 具有三螺旋结构的蛋白质物质及其制造方法
ES2593049T3 (es) * 2009-01-09 2016-12-05 Apogenix Ag Proteínas de fusión que forman trímeros
US8993343B2 (en) * 2009-01-28 2015-03-31 Korea Research Institute Of Bioscience And Biotechnology CD93 or use of soluble fragment thereof
WO2011006982A2 (en) * 2009-07-17 2011-01-20 Rigshospitalet Inhibitors of complement activation
ES2678143T3 (es) 2010-01-19 2018-08-09 President And Fellows Of Harvard College Opsonina obtenida por ingeniería genética para la detección y el tratamiento de microorganismos patógenos
EP2559760B1 (de) 2010-03-04 2015-10-21 Fuso Pharmaceutical Industries, Ltd. Collectin Fragment zur linderung von Gefässkrankheiten
US9815876B2 (en) * 2010-03-05 2017-11-14 Omeros Corporation Chimeric inhibitor molecules of complement activation
EP2734843A2 (de) 2011-07-18 2014-05-28 President and Fellows of Harvard College Manipulierte moleküle zur anzielung von mikroben und ihre verwendungen
AU2013225823A1 (en) 2012-02-29 2014-09-18 President And Fellows Of Harvard College Rapid antibiotic susceptibility testing
EP2976642A4 (de) 2013-03-15 2016-09-21 Harvard College Verfahren und zusammensetzungen zur verbesserung der erkennung und/oder aufnahme einer zieleinheit
US9988617B2 (en) 2013-05-21 2018-06-05 President And Fellows Of Harvard College Engineered heme-binding compositions and uses thereof
EP3546474B1 (de) 2013-12-18 2021-07-07 President and Fellows of Harvard College Crp-erfassung/-detektion von grampositiven bakterien
JP2014218510A (ja) * 2014-08-11 2014-11-20 アポゲニクスゲゼルシャフト ミット ベシュレンクテルハフツングＡｐｏｇｅｎｉｘ ＧｍｂＨ 三量体形成融合タンパク質
CN108289928B (zh) 2015-08-06 2024-09-17 哈佛大学校长及研究员协会 改进的微生物-结合分子和其用途
JP2016210791A (ja) * 2016-08-03 2016-12-15 アポゲニクス アーゲー 三量体形成融合タンパク質
SG10201802979VA (en) * 2018-04-10 2019-11-28 Kah Meng Lim Immunological extract and method of production
WO2022079308A1 (en) * 2020-10-16 2022-04-21 Institut Pasteur Chimeric constructs useful in vaccination and cancer therapy
CN113307857B (zh) * 2021-01-14 2022-11-01 艾时斌 从表皮生长因子、凝集素和Tat蛋白衍生的支架蛋白
CN118354785A (zh) * 2021-10-07 2024-07-16 奥默罗斯公司 靶向催化性补体活化分子及其使用方法
CN114344453A (zh) * 2022-01-18 2022-04-15 华南师范大学 一种罗非鱼cl-k1在制备预防和/或治疗罗非鱼病害的药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999010001A1 (en) * 1997-08-21 1999-03-04 Takara Shuzo Co., Ltd. Carcinostatic agents
US7049099B2 (en) * 1998-01-23 2006-05-23 Fuso Pharmaceutical Industries, Ltd. Recombinant human mannan-binding proteins and producing method of the same
JPH11206378A (ja) * 1998-01-23 1999-08-03 Fuso Pharmaceutical Industries Ltd 組換えヒトマンナン結合タンパク質およびその製造方法
US6337193B1 (en) * 1998-11-24 2002-01-08 Aptagen, Inc. Expression of manose-binding protein in methylotrophic yeast
CA2372128A1 (en) * 1999-05-14 2000-11-23 Steffen Thiel Novel indications of mannan-binding lectin (mbl) in the treatment of immunocompromised individuals
US20030186419A1 (en) * 1999-12-02 2003-10-02 Jensenius Jens Christian Masp-3, a complement-fixing enzyme, and uses for it
ATE434661T1 (de) * 2000-07-13 2009-07-15 Helion Biotech Aps Masp-2, ein komplement fixierendes enzym, und dessen verwendungen
US20050137126A1 (en) * 2003-04-09 2005-06-23 Natlmmune A/S Treatment of SARS in individuals

Also Published As

Publication number Publication date
ES2279981T3 (es) 2007-09-01
EP1539964A2 (de) 2005-06-15
EP1539964B1 (de) 2006-12-27
WO2004024925A3 (en) 2004-06-24
DE60310736T2 (de) 2007-10-11
DK1539964T3 (da) 2007-05-07
DE60310736D1 (de) 2007-02-08
AU2003260286A1 (en) 2004-04-30
CN1694961A (zh) 2005-11-09
JP2005537807A (ja) 2005-12-15
WO2004024925A8 (en) 2004-05-21
WO2004024925A2 (en) 2004-03-25
US20060188963A1 (en) 2006-08-24
PT1539964E (pt) 2007-04-30

Similar Documents

Publication Publication Date Title
DK1539964T3 (da) Cellectin-komplementaktiverende proteinkimærer
HUP9904023A2 (hu) Leptin antagonisták alkalmazása inzulin rezisztencia kezelésére II. típusú cukorbajban
HRP20010877B1 (hr) Pripravci za prevenciju i liječenje amiloidogenskih bolesti
DE69412243D1 (de) Biologisch aktive peptide aus funktionellen domaenen des bakteriziden/ die permeabilitaet erhoehenden proteins und ihre verwendung
DE602004011770D1 (de) Fusionsproteine
ATE198050T1 (de) Therapeutische anwendungen von bpi-protein- produkten zur behandlung von humaner meningococcämia
DE69410254D1 (de) Behandlung von mycobakteriellen erkrankungen durch verabreichung von bakrerientötende, durchlässigkeitserhöhende proteinfragmente
KR950702248A (ko) 단백질을 기초로 한 전달 시스템(protein based delivery system)
BR0313239A (pt) Composto, composição farmacêutica, e, métodos de tratamento ou prevenção de dor e inflamação e de doenças
MXPA05008704A (es) Proteinas de fusion de muteinas de interferon alfa con propiedades mejoradas.
FI933862A0 (fi) Loesliga ligander foer cd40
WO2001091773A3 (en) Method of stimulating hair growth
DE69133068D1 (de) Tumor-zerstörende effekte von enterotoxinen und verwandten verbindungen
DE69840024D1 (de) Antimikrobielle Peptide, abstammend von Ubiquicidin
DE69914911D1 (de) Pharmazeutische präparate zur bekämpfung oder prophylaxe von mikroorganismen infizierten oberflächen
DE60231825D1 (de) Behandlung von infektionen verursacht von mikroorganismen
ATE326534T1 (de) Methode zur behandlung von muskelkrankheiten
DE50113010D1 (de) Verfahren zur gewinnung und anwendung neuer humaner defensine als biologisch aktive eiweisstoffe zur behandlung von infektionen und anderen erkrankungen
DE69131355D1 (de) Die knochenresorption hemmende verbindungen und zusammensetzungen
ATE368687T1 (de) Thrombopoietinproteine mit verbesserten eigenschaften
BG103905A (en) New bpc peptide salts with organoprotective activity, method for their preparation and application in medicine
NO945031D0 (no) Anvendelse av en hymenopteragift til fremstilling av et medikament for behandling av DNA-virusinfeksjoner
ATE338770T1 (de) Mit bh4 fusionierte polypeptide
YU8395A (sh) Protein sa tpo aktivnošću
BR0012740A (pt) Compostos para tratamento de distúrbios do sistema infeccioso e imune e métodos para seu emprego

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1539964

Country of ref document: EP

REN Ceased due to non-payment of the annual fee