DK1339703T3 - Fremgangsmåde til fremstilling af paclitaxel - Google Patents

Fremgangsmåde til fremstilling af paclitaxel

Info

Publication number
DK1339703T3
DK1339703T3 DK01985349T DK01985349T DK1339703T3 DK 1339703 T3 DK1339703 T3 DK 1339703T3 DK 01985349 T DK01985349 T DK 01985349T DK 01985349 T DK01985349 T DK 01985349T DK 1339703 T3 DK1339703 T3 DK 1339703T3
Authority
DK
Denmark
Prior art keywords
preparing paclitaxel
paclitaxel
preparing
preparation
deacetylbaccatine iii
Prior art date
Application number
DK01985349T
Other languages
Danish (da)
English (en)
Inventor
Ezio Bombardelli
Arturo Battaglia
Paolo Dambruoso
Andrea Guerrini
Alessandro Pontiroli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of DK1339703T3 publication Critical patent/DK1339703T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK01985349T 2000-12-06 2001-12-03 Fremgangsmåde til fremstilling af paclitaxel DK1339703T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI002654A IT1319682B1 (it) 2000-12-06 2000-12-06 Procedimento di sintesi del paclitaxel.

Publications (1)

Publication Number Publication Date
DK1339703T3 true DK1339703T3 (da) 2004-09-27

Family

ID=11446197

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01985349T DK1339703T3 (da) 2000-12-06 2001-12-03 Fremgangsmåde til fremstilling af paclitaxel

Country Status (22)

Country Link
US (1) US6768012B2 (cs)
EP (1) EP1339703B1 (cs)
JP (1) JP2004515497A (cs)
KR (1) KR100846891B1 (cs)
CN (1) CN1286828C (cs)
AT (1) ATE267820T1 (cs)
AU (2) AU2002234535B2 (cs)
CA (1) CA2430814C (cs)
CZ (1) CZ300024B6 (cs)
DE (1) DE60103560T2 (cs)
DK (1) DK1339703T3 (cs)
ES (1) ES2221656T3 (cs)
HU (1) HU229373B1 (cs)
IL (2) IL156331A0 (cs)
IT (1) IT1319682B1 (cs)
NO (1) NO328505B1 (cs)
PL (1) PL195121B1 (cs)
PT (1) PT1339703E (cs)
RU (1) RU2276147C2 (cs)
SK (1) SK286616B6 (cs)
TR (1) TR200401435T4 (cs)
WO (1) WO2002046177A1 (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319682B1 (it) * 2000-12-06 2003-10-23 Indena Spa Procedimento di sintesi del paclitaxel.
ITMI20012185A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
EP1599457A4 (en) * 2003-02-04 2008-05-07 Natural Pharmaceuticals Inc METHOD AND COMPOSITION FOR PREPARING A COMPOUND WITH AN ACTIVE BENZOYLATING ACTIVE INCLUDING RING CHLORINE-FREE ACTIVE
CN1303077C (zh) 2004-01-16 2007-03-07 桂林晖昂生化药业有限责任公司 合成紫杉烷的制备工艺
ITMI20050614A1 (it) * 2005-04-12 2006-10-13 Indena Spa Processo per la purificazione della 10-deacetilbaccatina iii dalla 10-deacetil-2-debenzoil-2-pentenoilbaccatina iii
DK1854799T3 (da) * 2006-05-12 2011-07-18 Indena Spa Fremgangsmåde til fremstilling af et taxanderivat
CN103254187B (zh) * 2012-02-15 2016-05-25 浙江大学宁波理工学院 一种紫杉烷衍生物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2696460B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
US5380751A (en) * 1992-12-04 1995-01-10 Bristol-Myers Squibb Company 6,7-modified paclitaxels
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
US5917062A (en) * 1997-11-21 1999-06-29 Indena S.P.A Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
US6020507A (en) 1998-03-02 2000-02-01 Bristol-Myers Squibb Company Synthesis of paclitaxel from baccatin III by protection of the 7-hydroxyl of baccatin III using a strong base and an electrophile
IT1319682B1 (it) * 2000-12-06 2003-10-23 Indena Spa Procedimento di sintesi del paclitaxel.

Also Published As

Publication number Publication date
AU3453502A (en) 2002-06-18
PL366120A1 (en) 2005-01-24
US6768012B2 (en) 2004-07-27
KR100846891B1 (ko) 2008-07-17
SK286616B6 (sk) 2009-02-05
DE60103560D1 (de) 2004-07-01
KR20030055332A (ko) 2003-07-02
ATE267820T1 (de) 2004-06-15
NO328505B1 (no) 2010-03-08
IL156331A (en) 2006-10-31
ES2221656T3 (es) 2005-01-01
TR200401435T4 (tr) 2004-08-23
US20040049060A1 (en) 2004-03-11
WO2002046177A1 (en) 2002-06-13
IT1319682B1 (it) 2003-10-23
CZ20031534A3 (cs) 2003-08-13
HU229373B1 (hu) 2013-11-28
IL156331A0 (en) 2004-01-04
HUP0500615A2 (hu) 2005-11-28
DE60103560T2 (de) 2004-09-16
CN1509277A (zh) 2004-06-30
CA2430814A1 (en) 2002-06-13
PL195121B1 (pl) 2007-08-31
NO20032558L (no) 2003-06-05
NO20032558D0 (no) 2003-06-05
ITMI20002654A1 (it) 2002-06-06
SK6972003A3 (en) 2003-11-04
HK1063052A1 (en) 2004-12-10
CZ300024B6 (cs) 2009-01-14
JP2004515497A (ja) 2004-05-27
AU2002234535B2 (en) 2006-02-02
RU2276147C2 (ru) 2006-05-10
CN1286828C (zh) 2006-11-29
EP1339703B1 (en) 2004-05-26
CA2430814C (en) 2009-04-07
EP1339703A1 (en) 2003-09-03
PT1339703E (pt) 2004-08-31

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