DK1354204T3 - HCV-antigen/antistof-kombinationssay - Google Patents

HCV-antigen/antistof-kombinationssay

Info

Publication number
DK1354204T3
DK1354204T3 DK01952160T DK01952160T DK1354204T3 DK 1354204 T3 DK1354204 T3 DK 1354204T3 DK 01952160 T DK01952160 T DK 01952160T DK 01952160 T DK01952160 T DK 01952160T DK 1354204 T3 DK1354204 T3 DK 1354204T3
Authority
DK
Denmark
Prior art keywords
hcv
antibody
antigens
kombinationssay
antigen
Prior art date
Application number
DK01952160T
Other languages
English (en)
Other versions
DK1354204T4 (da
Inventor
David Y Chien
Phillip Arcangel
Laura Tandeske
Carlos George-Nasciemento
Doris Coit
Angelica Medina-Selby
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27395684&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1354204(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of DK1354204T3 publication Critical patent/DK1354204T3/da
Publication of DK1354204T4 publication Critical patent/DK1354204T4/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/18Togaviridae; Flaviviridae
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/10Detection of antigens from microorganism in sample from host
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK01952160.8T 2000-06-15 2001-06-14 HCV-antigen/antistof-kombinationssay DK1354204T4 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21208200P 2000-06-15 2000-06-15
US28086701P 2001-04-02 2001-04-02
US28081101P 2001-04-02 2001-04-02
PCT/US2001/019369 WO2001096875A2 (en) 2000-06-15 2001-06-14 Hcv antigen/antibody combination assay

Publications (2)

Publication Number Publication Date
DK1354204T3 true DK1354204T3 (da) 2007-04-10
DK1354204T4 DK1354204T4 (da) 2010-06-14

Family

ID=27395684

Family Applications (2)

Application Number Title Priority Date Filing Date
DK01952160.8T DK1354204T4 (da) 2000-06-15 2001-06-14 HCV-antigen/antistof-kombinationssay
DK01952156T DK1350105T3 (da) 2000-06-15 2001-06-14 Immunoanalyser for enti-HCV-antistoffer

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK01952156T DK1350105T3 (da) 2000-06-15 2001-06-14 Immunoanalyser for enti-HCV-antistoffer

Country Status (22)

Country Link
US (5) US6632601B2 (da)
EP (2) EP1354204B2 (da)
JP (3) JP4837229B2 (da)
CN (3) CN1214244C (da)
AT (2) ATE368221T1 (da)
AU (2) AU2001272948A1 (da)
BG (1) BG66205B1 (da)
BR (2) BRPI0111731C1 (da)
CA (2) CA2412035C (da)
CY (2) CY1107537T1 (da)
CZ (1) CZ304185B6 (da)
DE (2) DE60129598T2 (da)
DK (2) DK1354204T4 (da)
ES (2) ES2277932T5 (da)
HU (1) HU228873B1 (da)
MX (2) MXPA02012424A (da)
NO (1) NO332275B1 (da)
PL (1) PL213363B1 (da)
PT (2) PT1354204E (da)
SI (1) SI1354204T2 (da)
SK (1) SK287694B6 (da)
WO (2) WO2001096870A2 (da)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08510240A (ja) * 1993-05-12 1996-10-29 カイロン コーポレイション C型肝炎ウイルスe2/ns1領域の保存モチーフ
US7491808B2 (en) * 2000-06-15 2009-02-17 Novartis Vaccines And Diagnostics, Inc. HCV non-structural protein mutants and uses thereof
DK1354204T4 (da) * 2000-06-15 2010-06-14 Novartis Vaccines & Diagnostic HCV-antigen/antistof-kombinationssay
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
JP5175417B2 (ja) 2000-08-17 2013-04-03 トリペップ アクチ ボラゲット リバビリンを含むワクチンおよびその使用方法
RU2286172C2 (ru) 2000-08-17 2006-10-27 Трипеп Аб Вакцины, содержащие рибавирин, и способы их использования
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
DE10106295C1 (de) * 2001-02-02 2002-08-22 Gaifar German American Inst Fo Protein mit mehreren Antigen-Epitop-Sequenzen, welches immobilisiert ist
AU785380B2 (en) * 2001-03-28 2007-03-15 Ortho-Clinical Diagnostics, Inc. A hepatitis C antigen - antibody combination assay for the early detection of HCV infection
EP1412538B1 (en) 2001-06-26 2013-03-27 Abbott Laboratories Methods for the simultaneous detection of hcv antigens and hcv antibodies
US7101683B2 (en) 2001-06-26 2006-09-05 Abbott Laboratories Methods for the simultaneous detection of HCV antigens and HCV antibodies
US7049060B2 (en) * 2001-11-05 2006-05-23 Ortho-Clinical Diagnostics, Inc. HCV anti-core monoclonal antibodies
US7332269B2 (en) * 2001-11-11 2008-02-19 Ortho-Clinical Diagnostics, Inc. HCV core protein sequences
FR2839555B1 (fr) 2002-05-10 2007-07-27 Bio Rad Pasteur Procede de detection simultanee d'un antigene et d'un anticorps d'un microorganisme infectieux
ATE410693T1 (de) 2002-09-09 2008-10-15 Novartis Vaccines & Diagnostic Hcv-test
US20040152070A1 (en) * 2003-02-04 2004-08-05 Shah Dinesh O. Method of detection of HCV antibodies in combination assay or sole antibody assay
WO2005019828A1 (en) 2003-08-20 2005-03-03 Amorfix Life Sciences Ltd. Epitope protection assay and method for detecting protein conformations
ES2377978T3 (es) * 2004-08-27 2012-04-03 Novartis Vaccines And Diagnostics, Inc. Mutantes de proteínas no estructurales de VHC y usos de los mismos
US7658930B2 (en) * 2005-02-02 2010-02-09 Peng Cui Kit for detecting the antibody of HCV and its preparing method
CA2630220C (en) 2005-11-22 2020-10-13 Doris Coit Norovirus and sapovirus antigens
US7887803B2 (en) 2005-12-02 2011-02-15 Amorfix Life Sciences Methods and compositions to treat misfolded-SOD1 mediated diseases
US7794692B2 (en) * 2005-12-02 2010-09-14 Amorfix Life Sciences Ltd. Methods and compositions for detecting amyotrophic lateral sclerosis
JP5823663B2 (ja) 2006-03-03 2015-11-25 プロミス ニューロサイエンシズ インコーポレイテッド ミスフォールドsod1媒介疾患を処置および検出するための方法および組成物
CN1908666B (zh) * 2006-08-14 2010-05-12 武汉大学 一种检测乙肝核心抗体的双夹心法酶联免疫诊断试剂盒及应用
EP2185195A2 (en) 2007-08-16 2010-05-19 Tripep Ab Immunogen platform
EP2414839B1 (fr) * 2009-03-30 2014-06-25 Biomérieux Support solide de détection du vhc
US20100297607A1 (en) * 2009-05-20 2010-11-25 Jian Zheng Reagents For HCV Antigen-Antibody Combination Assays
BR112012025364A2 (pt) 2010-04-07 2015-09-22 Novartis Ag método para geração de partícula semelhante a vírus de parvovírus b19
EP2583101B1 (en) * 2010-06-17 2015-09-16 Koninklijke Philips N.V. Multi epitope assay
AU2011276328C1 (en) 2010-07-06 2016-01-21 Novartis Ag Norovirus derived immunogenic compositions and methods
US20120009196A1 (en) * 2010-07-08 2012-01-12 Abbott Laboratories Monoclonal antibodies against hepatitis c virus core protein
JP5911889B2 (ja) * 2011-01-13 2016-04-27 オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッドOrtho−Clinical Diagnostics, Inc. 梅毒トレポネーマトリプレット抗原
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
BR112015023239A8 (pt) * 2013-03-14 2018-04-17 Abbott Lab ensaio de combinação de anticorpo-antígeno de hcv e métodos e composições para uso do mesmo
JP2016512241A (ja) 2013-03-14 2016-04-25 アボット・ラボラトリーズAbbott Laboratories 改良された抗体検出のためのhcvns3組換え抗原およびこの突然変異体
CN113549148B (zh) 2013-03-14 2025-11-21 雅培制药有限公司 Hcv核心脂质结合结构域单克隆抗体
CN103630690B (zh) * 2013-12-17 2014-08-20 朱之炜 丙型肝炎病毒抗原抗体联合检测试剂盒及其检测方法
WO2016160046A1 (en) 2015-03-27 2016-10-06 Ortho-Clinical Diagnostics, Inc. Hcv ns4a/modified ns3 polypeptides and uses thereof
WO2016172121A1 (en) * 2015-04-20 2016-10-27 Qoolabs, Inc. Camelid single-domain hcv antibodies and methods of use
CN118376776A (zh) * 2017-09-27 2024-07-23 生物辐射实验室股份有限公司 数字化亲和连接试验
CN110261616B (zh) * 2019-04-30 2021-07-20 广东菲鹏生物有限公司 一种丙型肝炎病毒检测试剂盒
CN115057943B (zh) * 2022-06-22 2025-03-14 杭州水芭莎生物医药科技有限公司 一种抗菌肽融合蛋白及其制备方法和应用
CN115838420B (zh) * 2022-10-31 2023-05-05 北京科跃中楷生物技术有限公司 一种可溶性hcv重组蛋白的制备方法及其制备的抗体检测试剂

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
GB2212511B (en) * 1987-11-18 1992-01-22 Chiron Corp Hepatitis c virus
US5350671A (en) 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US6171782B1 (en) 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
NZ227011A (en) * 1987-11-18 1992-03-26 Chiron Corp Non-a, non-b-hepatitis (hepatitis c) antigens, proteins, nucleotide sequences, vaccines and kits
JP2730153B2 (ja) 1989-03-16 1998-03-25 日本合成ゴム株式会社 熱可塑性樹脂組成物およびその製造方法
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
DK0398748T3 (da) * 1989-05-18 2002-03-18 Chiron Corp NANBV-diagnostika: polynukleotider anvendelige til screening for hepatitis C virus
HU217025B (hu) * 1990-04-04 1999-11-29 Chiron Corp. Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben
US6312889B1 (en) 1990-04-04 2001-11-06 Chiron Corporation Combinations of hepatitis c virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US6194140B1 (en) * 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
PT97247B (pt) * 1991-04-03 1997-10-31 Chiron Corp Processo de preparacao de combinacoes de antigenios do virus da hepapite c (hcv) para uso em imunoensaios para anticorpos anti-hcv
WO1993000365A2 (en) 1991-06-24 1993-01-07 Chiron Corporation Hepatitis c virus (hcv) polypeptides
UA39944C2 (uk) 1992-07-07 2001-07-16 Чірон Корпорейшн Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
EP0651807B1 (en) * 1993-04-27 2007-09-12 N.V. Innogenetics S.A. New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents
US6001604A (en) * 1993-12-29 1999-12-14 Bio-Technology General Corp. Refolding of proinsulins without addition of reducing agents
JP3217600B2 (ja) 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非a非b型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
DE4428705A1 (de) * 1994-08-12 1996-02-15 Boehringer Mannheim Gmbh Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus
US5843752A (en) 1995-05-12 1998-12-01 Schering Corporation Soluble active hepatitis C virus protease
US5990276A (en) 1996-05-10 1999-11-23 Schering Corporation Synthetic inhibitors of hepatitis C virus NS3 protease
CA2250723C (en) * 1996-05-24 2012-07-17 Chiron Corporation Multiple epitope fusion protein
US6514731B1 (en) * 1996-05-24 2003-02-04 Chiron Corporation Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
US6322965B1 (en) * 1997-02-10 2001-11-27 Advanced Life Science Institute, Inc. Chimera antigen peptide
AU9497998A (en) * 1997-09-22 1999-04-12 Chiron Corporation Method for detecting antibodies in a sample
US7316905B1 (en) * 1998-07-30 2008-01-08 Advanced Life Science Institute, Inc. Method for measurement of hepatitis C virus
DK1354204T4 (da) * 2000-06-15 2010-06-14 Novartis Vaccines & Diagnostic HCV-antigen/antistof-kombinationssay

Also Published As

Publication number Publication date
HUP0500444A3 (en) 2010-03-29
US20040096822A1 (en) 2004-05-20
DK1350105T3 (da) 2007-11-12
EP1354204A2 (en) 2003-10-22
SI1354204T2 (sl) 2010-09-30
CN100463922C (zh) 2009-02-25
NO20025878L (no) 2003-02-12
DK1354204T4 (da) 2010-06-14
BRPI0111731B8 (pt) 2016-08-23
AU2001272948A1 (en) 2001-12-24
US20020192639A1 (en) 2002-12-19
AU2001272945A1 (en) 2001-12-24
JP2011125350A (ja) 2011-06-30
US7241879B2 (en) 2007-07-10
DE60125240D1 (de) 2007-01-25
US6797809B2 (en) 2004-09-28
ATE368221T1 (de) 2007-08-15
EP1354204B1 (en) 2006-12-13
HU228873B1 (hu) 2013-06-28
BG66205B1 (bg) 2012-01-31
NO20025878D0 (no) 2002-12-06
US6630298B2 (en) 2003-10-07
NO332275B1 (no) 2012-08-13
ES2277932T5 (es) 2010-06-28
EP1350105B1 (en) 2007-07-25
CY1107537T1 (el) 2013-03-13
DE60129598T2 (de) 2008-04-17
CN1660913A (zh) 2005-08-31
MXPA02012401A (es) 2003-04-25
ES2277932T3 (es) 2007-08-01
BRPI0111731B1 (pt) 2016-07-05
WO2001096875A3 (en) 2003-08-28
ES2288969T3 (es) 2008-02-01
CA2413003C (en) 2013-08-13
CN1466682A (zh) 2004-01-07
US20040265801A1 (en) 2004-12-30
PL213363B1 (pl) 2013-02-28
US20040063092A1 (en) 2004-04-01
JP2004506878A (ja) 2004-03-04
CA2412035C (en) 2012-04-10
DE60125240T3 (de) 2010-10-28
EP1350105A2 (en) 2003-10-08
SI1354204T1 (sl) 2007-04-30
PT1350105E (pt) 2007-08-13
BR0111731A (pt) 2004-02-10
ATE348337T1 (de) 2007-01-15
JP4834279B2 (ja) 2011-12-14
BG107441A (bg) 2004-01-30
BRPI0111682B1 (pt) 2017-09-19
DE60129598D1 (de) 2007-09-06
WO2001096870A2 (en) 2001-12-20
CN1489692A (zh) 2004-04-14
PT1354204E (pt) 2007-03-30
WO2001096875A2 (en) 2001-12-20
CN1214244C (zh) 2005-08-10
MXPA02012424A (es) 2003-04-25
CZ304185B6 (cs) 2013-12-11
JP2004510133A (ja) 2004-04-02
PL365599A1 (en) 2005-01-10
CA2413003A1 (en) 2001-12-20
WO2001096875A9 (en) 2002-08-15
HK1061861A1 (en) 2004-10-08
US20020146685A1 (en) 2002-10-10
SK287694B6 (sk) 2011-06-06
CY1106820T1 (el) 2012-05-23
US7319144B2 (en) 2008-01-15
HUP0500444A2 (hu) 2005-08-29
US6632601B2 (en) 2003-10-14
SK17772002A3 (sk) 2003-10-07
CN1256591C (zh) 2006-05-17
DE60125240T2 (de) 2007-07-12
HK1079796A1 (en) 2006-04-13
BRPI0111682B8 (pt) 2021-07-27
BR0111682A (pt) 2004-01-06
CA2412035A1 (en) 2001-12-20
BRPI0111731C1 (pt) 2021-07-27
JP4837229B2 (ja) 2011-12-14
CZ20024058A3 (cs) 2003-09-17
EP1354204B2 (en) 2010-04-21
WO2001096870A3 (en) 2003-07-31

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