ATE368221T1 - Immunoassays für anti-hcv-antikörper - Google Patents

Immunoassays für anti-hcv-antikörper

Info

Publication number
ATE368221T1
ATE368221T1 AT01952156T AT01952156T ATE368221T1 AT E368221 T1 ATE368221 T1 AT E368221T1 AT 01952156 T AT01952156 T AT 01952156T AT 01952156 T AT01952156 T AT 01952156T AT E368221 T1 ATE368221 T1 AT E368221T1
Authority
AT
Austria
Prior art keywords
hcv
antigens
multiple epitope
epitope fusion
immunoassays
Prior art date
Application number
AT01952156T
Other languages
English (en)
Inventor
David Chien
Phillip Arcangel
Laura Tandeske
Carlos George-Nasciemento
Doris Coit
Angelica Medina-Selby
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27395684&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE368221(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE368221T1 publication Critical patent/ATE368221T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT01952156T 2000-06-15 2001-06-14 Immunoassays für anti-hcv-antikörper ATE368221T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21208200P 2000-06-15 2000-06-15
US28081101P 2001-04-02 2001-04-02
US28086701P 2001-04-02 2001-04-02

Publications (1)

Publication Number Publication Date
ATE368221T1 true ATE368221T1 (de) 2007-08-15

Family

ID=27395684

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01952160T ATE348337T1 (de) 2000-06-15 2001-06-14 Hcv-antigen/antikörper-kombinations-assay
AT01952156T ATE368221T1 (de) 2000-06-15 2001-06-14 Immunoassays für anti-hcv-antikörper

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT01952160T ATE348337T1 (de) 2000-06-15 2001-06-14 Hcv-antigen/antikörper-kombinations-assay

Country Status (22)

Country Link
US (5) US6630298B2 (de)
EP (2) EP1354204B2 (de)
JP (3) JP4834279B2 (de)
CN (3) CN100463922C (de)
AT (2) ATE348337T1 (de)
AU (2) AU2001272945A1 (de)
BG (1) BG66205B1 (de)
BR (2) BRPI0111731C1 (de)
CA (2) CA2412035C (de)
CY (2) CY1107537T1 (de)
CZ (1) CZ304185B6 (de)
DE (2) DE60125240T3 (de)
DK (2) DK1350105T3 (de)
ES (2) ES2277932T5 (de)
HU (1) HU228873B1 (de)
MX (2) MXPA02012424A (de)
NO (1) NO332275B1 (de)
PL (1) PL213363B1 (de)
PT (2) PT1350105E (de)
SI (1) SI1354204T2 (de)
SK (1) SK287694B6 (de)
WO (2) WO2001096870A2 (de)

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US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
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ES2312806T3 (es) 2002-09-09 2009-03-01 Novartis Vaccines And Diagnostics, Inc. Ensayo de vhc.
US20040152070A1 (en) * 2003-02-04 2004-08-05 Shah Dinesh O. Method of detection of HCV antibodies in combination assay or sole antibody assay
EP1668369B1 (de) 2003-08-20 2016-01-06 ProMIS Neurosciences Inc. Epitopschutztest und verfahren zum nachweis von proteinkonformationen
EP1802778B1 (de) * 2004-08-27 2011-10-05 Novartis Vaccines and Diagnostics, Inc. Hcv-antigene zur mehrfachen epitopfusion mit modifizierten proteolytischen spaltungsorten und verwendungen davon
EP1845378A4 (de) * 2005-02-02 2008-09-17 Peng Cui Kit zum nachweis des antikörpers von hcv und herstellungsverfahren dafür
ES2514316T3 (es) 2005-11-22 2014-10-28 Novartis Vaccines And Diagnostics, Inc. Partículas similares a virus (VLPs) de Norovirus y Sapovirus
US7887803B2 (en) 2005-12-02 2011-02-15 Amorfix Life Sciences Methods and compositions to treat misfolded-SOD1 mediated diseases
US7977314B2 (en) 2005-12-02 2011-07-12 Amorfix Life Sciences Limited Methods and compositions to treat and detect misfolded-SOD1 mediated diseases
US7794692B2 (en) * 2005-12-02 2010-09-14 Amorfix Life Sciences Ltd. Methods and compositions for detecting amyotrophic lateral sclerosis
CN1908666B (zh) * 2006-08-14 2010-05-12 武汉大学 一种检测乙肝核心抗体的双夹心法酶联免疫诊断试剂盒及应用
US8071561B2 (en) 2007-08-16 2011-12-06 Chrontech Pharma Ab Immunogen platform
WO2010112733A1 (fr) * 2009-03-30 2010-10-07 bioMérieux Support solide de détection du vhc
US20100297607A1 (en) * 2009-05-20 2010-11-25 Jian Zheng Reagents For HCV Antigen-Antibody Combination Assays
US9744228B2 (en) 2010-04-07 2017-08-29 Norvartis Ag Method for generating a parvovirus B19 virus-like particle
CN102947703A (zh) * 2010-06-17 2013-02-27 皇家飞利浦电子股份有限公司 多表位测定
AU2011276328C1 (en) 2010-07-06 2016-01-21 Novartis Ag Norovirus derived immunogenic compositions and methods
WO2012006500A2 (en) * 2010-07-08 2012-01-12 Abbott Laboratories Monoclonal antibodies against hepatitis c virus core protein
CN108085330A (zh) * 2011-01-13 2018-05-29 奥索临床诊断有限公司 苍白密螺旋体三联抗原
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
WO2014143343A1 (en) 2013-03-14 2014-09-18 Abbott Laboratories Hcv core lipid binding domain monoclonal antibodies
MX362075B (es) 2013-03-14 2019-01-07 Abbott Lab Ensayo de combinación de antígeno-anticuerpo del virus de la hepatitis c (vhc) y métodos y composiciones para usarlo.
JP2016512241A (ja) 2013-03-14 2016-04-25 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ 改良された抗体検出のためのｈｃｖｎｓ３組換え抗原およびこの突然変異体
CN103630690B (zh) * 2013-12-17 2014-08-20 朱之炜 丙型肝炎病毒抗原抗体联合检测试剂盒及其检测方法
CA2980718C (en) 2015-03-27 2021-06-01 Ortho-Clinical Diagnostics, Inc. Hcv ns4a/modified ns3 polypeptides and uses thereof
US20180292408A1 (en) * 2015-04-20 2018-10-11 Qoolabs, Inc. Camelid single-domain hcv antibodies and methods of use
EP4462123A3 (de) * 2017-09-27 2025-02-12 Bio-Rad Laboratories, Inc. Test für digitale affinitätsverknüpfung
CN110261616B (zh) * 2019-04-30 2021-07-20 广东菲鹏生物有限公司 一种丙型肝炎病毒检测试剂盒
CN115057943B (zh) * 2022-06-22 2025-03-14 杭州水芭莎生物医药科技有限公司 一种抗菌肽融合蛋白及其制备方法和应用
CN115838420B (zh) * 2022-10-31 2023-05-05 北京科跃中楷生物技术有限公司 一种可溶性hcv重组蛋白的制备方法及其制备的抗体检测试剂

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Also Published As

Publication number Publication date
CN1214244C (zh) 2005-08-10
US20040063092A1 (en) 2004-04-01
CA2412035C (en) 2012-04-10
BRPI0111682B8 (pt) 2021-07-27
CN1489692A (zh) 2004-04-14
DK1350105T3 (da) 2007-11-12
SI1354204T2 (sl) 2010-09-30
AU2001272945A1 (en) 2001-12-24
EP1354204A2 (de) 2003-10-22
CY1107537T1 (el) 2013-03-13
US7241879B2 (en) 2007-07-10
BG66205B1 (bg) 2012-01-31
EP1354204B2 (de) 2010-04-21
JP4837229B2 (ja) 2011-12-14
NO20025878D0 (no) 2002-12-06
JP2004506878A (ja) 2004-03-04
ES2277932T5 (es) 2010-06-28
EP1350105B1 (de) 2007-07-25
CZ20024058A3 (cs) 2003-09-17
WO2001096870A2 (en) 2001-12-20
CZ304185B6 (cs) 2013-12-11
PL365599A1 (en) 2005-01-10
PT1354204E (pt) 2007-03-30
CN1466682A (zh) 2004-01-07
WO2001096875A9 (en) 2002-08-15
DE60129598T2 (de) 2008-04-17
CY1106820T1 (el) 2012-05-23
HUP0500444A3 (en) 2010-03-29
EP1350105A2 (de) 2003-10-08
US6630298B2 (en) 2003-10-07
MXPA02012424A (es) 2003-04-25
CN1256591C (zh) 2006-05-17
SK17772002A3 (sk) 2003-10-07
PT1350105E (pt) 2007-08-13
DK1354204T4 (da) 2010-06-14
BRPI0111731B8 (pt) 2016-08-23
DE60125240T3 (de) 2010-10-28
WO2001096875A3 (en) 2003-08-28
US20040096822A1 (en) 2004-05-20
US6632601B2 (en) 2003-10-14
BRPI0111731C1 (pt) 2021-07-27
BR0111682A (pt) 2004-01-06
ES2277932T3 (es) 2007-08-01
CA2413003A1 (en) 2001-12-20
CN100463922C (zh) 2009-02-25
HUP0500444A2 (hu) 2005-08-29
AU2001272948A1 (en) 2001-12-24
ES2288969T3 (es) 2008-02-01
DE60125240T2 (de) 2007-07-12
US20040265801A1 (en) 2004-12-30
US20020192639A1 (en) 2002-12-19
EP1354204B1 (de) 2006-12-13
HK1061861A1 (en) 2004-10-08
JP4834279B2 (ja) 2011-12-14
US20020146685A1 (en) 2002-10-10
ATE348337T1 (de) 2007-01-15
PL213363B1 (pl) 2013-02-28
NO20025878L (no) 2003-02-12
US6797809B2 (en) 2004-09-28
HU228873B1 (hu) 2013-06-28
SK287694B6 (sk) 2011-06-06
SI1354204T1 (sl) 2007-04-30
NO332275B1 (no) 2012-08-13
MXPA02012401A (es) 2003-04-25
US7319144B2 (en) 2008-01-15
CA2413003C (en) 2013-08-13
CA2412035A1 (en) 2001-12-20
DK1354204T3 (da) 2007-04-10
JP2004510133A (ja) 2004-04-02
DE60125240D1 (de) 2007-01-25
WO2001096870A3 (en) 2003-07-31
DE60129598D1 (de) 2007-09-06
JP2011125350A (ja) 2011-06-30
WO2001096875A2 (en) 2001-12-20
BR0111731A (pt) 2004-02-10
CN1660913A (zh) 2005-08-31
HK1079796A1 (en) 2006-04-13
BRPI0111731B1 (pt) 2016-07-05
BG107441A (bg) 2004-01-30
BRPI0111682B1 (pt) 2017-09-19

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