DK1355930T3 - Fremgangsmåde til identifikation, isolering og fremstilling af antigener mod et specifikt patogen - Google Patents
Fremgangsmåde til identifikation, isolering og fremstilling af antigener mod et specifikt patogenInfo
- Publication number
- DK1355930T3 DK1355930T3 DK02716669T DK02716669T DK1355930T3 DK 1355930 T3 DK1355930 T3 DK 1355930T3 DK 02716669 T DK02716669 T DK 02716669T DK 02716669 T DK02716669 T DK 02716669T DK 1355930 T3 DK1355930 T3 DK 1355930T3
- Authority
- DK
- Denmark
- Prior art keywords
- specific pathogen
- isolating
- identifying
- antigens against
- producing antigens
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1041—Ribosome/Polysome display, e.g. SPERT, ARM
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0013001A AT410798B (de) | 2001-01-26 | 2001-01-26 | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1355930T3 true DK1355930T3 (da) | 2006-03-06 |
Family
ID=3636418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02716669T DK1355930T3 (da) | 2001-01-26 | 2002-01-21 | Fremgangsmåde til identifikation, isolering og fremstilling af antigener mod et specifikt patogen |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US7968297B2 (is) |
| EP (6) | EP2319861A1 (is) |
| JP (2) | JP2004531476A (is) |
| KR (4) | KR100901915B1 (is) |
| CN (2) | CN101492496A (is) |
| AT (2) | AT410798B (is) |
| AU (3) | AU2002247641B8 (is) |
| BR (1) | BR0207067A (is) |
| CA (2) | CA2792244A1 (is) |
| CZ (1) | CZ20032201A3 (is) |
| DE (1) | DE60207194T2 (is) |
| DK (1) | DK1355930T3 (is) |
| ES (1) | ES2252438T3 (is) |
| HU (1) | HUP0402048A3 (is) |
| IL (4) | IL157082A0 (is) |
| IS (1) | IS6895A (is) |
| MX (1) | MXPA03006702A (is) |
| NO (1) | NO20033364L (is) |
| NZ (4) | NZ551802A (is) |
| PL (2) | PL209115B1 (is) |
| RU (1) | RU2289817C2 (is) |
| SK (1) | SK10492003A3 (is) |
| WO (1) | WO2002059148A2 (is) |
| ZA (1) | ZA200305764B (is) |
Families Citing this family (134)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03006038A (es) | 2001-01-03 | 2005-02-14 | Willmar Poultry Co Inc | Composiciones inmunizantes y metodos de uso. |
| AT410798B (de) | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| MXPA03011701A (es) * | 2001-06-15 | 2004-12-06 | Nhibitex Inc | Anticuerpos monoclonales y policlonales de reaccion que reconocen las proteinas de superficie a partir de estafilococos coagulasa-negativos y staphylococcus aureus. |
| GB0200865D0 (en) * | 2002-01-16 | 2002-03-06 | Univ Bristol | Method |
| GB2387600A (en) * | 2002-04-19 | 2003-10-22 | Pantherix Ltd | Pantothenate kinase |
| US20050220788A1 (en) * | 2002-10-03 | 2005-10-06 | Intercell Ag | Use of molecules which interact with the haptoglobin receptor ligand binding |
| EP2287315A1 (en) | 2003-03-04 | 2011-02-23 | Intercell AG | Streptococcus pyogenes antigens |
| JP2007523609A (ja) | 2003-03-31 | 2007-08-23 | インターツェル・アクチェンゲゼルシャフト | 表皮ブドウ球菌抗原 |
| EP2311988A1 (en) | 2003-04-15 | 2011-04-20 | Intercell AG | S. pneumoniae antigens |
| US20060193866A1 (en) * | 2003-04-22 | 2006-08-31 | Intercell Ag | H pylori antigens |
| EP2289907A3 (en) | 2003-05-07 | 2011-08-31 | Intercell AG | Streptococcus agalactiae antigens I + II |
| US20080175856A1 (en) | 2003-05-30 | 2008-07-24 | Intercell Ag | Enterococcus Antigens |
| RU2257217C2 (ru) * | 2003-07-08 | 2005-07-27 | Государственное научное учреждение Институт экспериментальной ветеринарии Сибири и Дальнего Востока Сибирского отделения Россельхозакадемии (ГНУ ИЭВСиДВ СО РАСХН) | Гипериммунный тканевой препарат |
| KR20060065643A (ko) * | 2003-07-24 | 2006-06-14 | 머크 앤드 캄파니 인코포레이티드 | 스타필로코쿠스 아우레우스에 대한 방어 면역 반응을유도하는 폴리펩타이드 |
| WO2005009378A2 (en) * | 2003-07-24 | 2005-02-03 | Merck & Co., Inc. | Polypeptides for inducing a protective immune response against staphylococcus aureus |
| AU2004274977B2 (en) | 2003-09-19 | 2011-06-23 | Epitopix, Llc | Campylobacter polypeptides and methods of use |
| US20070134263A1 (en) * | 2004-02-18 | 2007-06-14 | Anderson Annaliesa S | Polypeptides for inducing a protective immune response against staphyloococcus aureus |
| EP1725255A4 (en) * | 2004-02-27 | 2007-07-11 | Merck & Co Inc | POLYPEPTIDES FOR THE INDUCTION OF A PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS AUREUS |
| JP2005278537A (ja) * | 2004-03-30 | 2005-10-13 | Dai Ichi Seiyaku Co Ltd | 新規ポリペプチド |
| US20070128183A1 (en) * | 2004-04-27 | 2007-06-07 | Intercell Ag | Td antigens |
| WO2006065272A2 (en) | 2004-05-21 | 2006-06-22 | Idaho Research Foundation, Inc. | Methods for altering acetic acid production and enhancing cell death in bacteria |
| EP1753441A2 (en) * | 2004-05-25 | 2007-02-21 | Merck & Co., Inc. | Polypeptides for inducing a protective immune response against staphylococcus aureus |
| CN1993141A (zh) * | 2004-06-04 | 2007-07-04 | 法麦克萨有限公司 | 诱导针对肺炎链球菌多糖的免疫应答 |
| FR2871159A1 (fr) * | 2004-06-08 | 2005-12-09 | Abag Sa | Nouvelles proteines permettant, notamment, la mise en evidence in vitro et la prevention des infections a staphylocoques a coagulase negative |
| FR2871237B1 (fr) * | 2004-06-08 | 2011-03-11 | Abag | Nouveaux polypeptides pour la mise en evidence in vitro et la prevention des infections staphylococciques sur protheses articulaires et autres materiels etrangers implantes |
| WO2007018482A2 (en) * | 2004-07-06 | 2007-02-15 | Merck & Co., Inc. | Polypeptides for inducing a protective immune response against staphylococcus aureus |
| US20080095792A1 (en) * | 2004-09-17 | 2008-04-24 | Anderson Annaliesa S | Polypeptides For Inducing A Protective Immune Response Against Staphylococcus Aureus |
| NZ553776A (en) | 2004-09-22 | 2010-05-28 | Glaxosmithkline Biolog Sa | Immunogenic composition comprising staphylococcal PNAG and Type 5 and/or 8 Capsular polysaccharide or oligosaccharide. |
| EP2298341A3 (en) | 2004-10-21 | 2011-07-13 | Wyeth LLC | Immunogenic compositions of staphylococcus epidermidis polypeptide and polynucleotide antigens |
| DE602005015605D1 (de) * | 2004-10-29 | 2009-09-03 | Intercell Ag | Hcv impfstoff für chronische hcv patienten |
| AU2006206577B2 (en) | 2005-01-21 | 2012-03-08 | Merck Sharp & Dohme Corp. | Polypeptides for inducing a protective immune response against Staphylococcus aureus |
| NZ556651A (en) | 2005-01-21 | 2010-05-28 | Epitopix Llc | Yersinia spp. polypeptides and methods of use |
| US8007811B2 (en) | 2005-02-14 | 2011-08-30 | Epitopix, Llc | Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use |
| EP1869461A1 (en) * | 2005-04-04 | 2007-12-26 | Viventia Biotech Inc. | Method and system for identification of antigen |
| WO2006121664A2 (en) * | 2005-05-05 | 2006-11-16 | Merck & Co., Inc. | Polypeptides for inducing a protective immune response against staphylococcus aureus |
| WO2006124644A2 (en) * | 2005-05-12 | 2006-11-23 | Board Of Regents, The University Of Texas System | Protein and antibody profiling using small molecule microarrays |
| AU2006267817A1 (en) * | 2005-07-14 | 2007-01-18 | Bharat Biotech International Limited | A vaccine for Staphylococcal infections |
| AU2007281934B2 (en) * | 2006-01-18 | 2012-11-15 | University Of Chicago | Compositions and methods related to Staphylococcal bacterium proteins |
| EP2476433A1 (en) | 2006-03-30 | 2012-07-18 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
| GB0610776D0 (en) * | 2006-05-31 | 2006-07-12 | Univ Bath | Novel applications for staphylococcus aureus Sbi protein |
| JP2010503384A (ja) * | 2006-09-15 | 2010-02-04 | インターセル アーゲー | ボレリア(Borrelia)抗原 |
| US20080102067A1 (en) * | 2006-10-25 | 2008-05-01 | Cook Mark E | Immunogenic composition |
| EP1923069A1 (en) | 2006-11-20 | 2008-05-21 | Intercell AG | Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto |
| EP1935984A1 (en) * | 2006-12-20 | 2008-06-25 | Unilever N.V. | Screening method for the identification of a preservative |
| AU2008251982A1 (en) | 2007-01-24 | 2008-11-20 | Merck Sharp & Dohme Corp. | Polypeptides for inducing a protective immune response against Staphylococcus epidermidis |
| JP2010521965A (ja) * | 2007-03-19 | 2010-07-01 | メルク・シャープ・エンド・ドーム・コーポレイション | スタフィロコッカス・エピデルミディス(Staphylococcusepidermidis)に対する防御免疫応答を誘発するポリペプチド |
| CN101883782A (zh) * | 2007-06-18 | 2010-11-10 | 英特塞尔股份公司 | 衣原体抗原 |
| US9181329B2 (en) | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
| JP5658564B2 (ja) | 2007-08-31 | 2015-01-28 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | ブドウ球菌肺疾患および状態に対する免疫に関連した方法および組成物 |
| AU2008313721B2 (en) * | 2007-10-18 | 2013-03-21 | Unilever Plc | Method for producing a foaming agent |
| CN101458255B (zh) * | 2007-12-14 | 2013-03-06 | 武汉大学 | 丙型肝炎病毒包膜抗原夹心法试剂盒及检测方法 |
| US20090196852A1 (en) * | 2008-02-04 | 2009-08-06 | Watkinson D Tobin | Compositions and methods for diagnosing and treating immune disorders |
| CN102015651B (zh) | 2008-03-03 | 2014-12-31 | Irm责任有限公司 | 作为tlr活性调节剂的化合物和组合物 |
| AU2009226949A1 (en) | 2008-03-17 | 2009-09-24 | Intercell Ag | Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto |
| WO2009158682A2 (en) * | 2008-06-27 | 2009-12-30 | Watkinson D Tobin | Compositions and methods for diagnosing and treating pathogenic disorders |
| US20100015171A1 (en) * | 2008-07-15 | 2010-01-21 | Statens Serum Institute | Vaccines comprising tb 10.4 |
| WO2010014304A1 (en) | 2008-07-29 | 2010-02-04 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
| US8318180B2 (en) * | 2008-09-30 | 2012-11-27 | University Of Maryland, Baltimore | Protective vaccine against Staphylococcus aureus biofilms comprising cell wall-associated immunogens |
| EP2341929B1 (en) * | 2008-10-06 | 2017-01-25 | University Of Chicago | Compositions and methods related to bacterial emp proteins |
| JP2012505645A (ja) * | 2008-10-16 | 2012-03-08 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 消泡剤を含むハイドロフォビン溶液 |
| MX2011005578A (es) | 2008-11-26 | 2011-06-30 | Merck Sharp & Dohme | Polipeptidos para inducir una respuesta inmune protectora contra staphylococcus aureus. |
| EP2376111A4 (en) | 2008-11-26 | 2013-01-09 | Merck Sharp & Dohme | POLYPEPTIDES FOR INDUCING A PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS AUREUS |
| RU2371201C1 (ru) * | 2008-12-15 | 2009-10-27 | Гурий Петрович Ступаков | Способ лечения хронических заболеваний |
| SG195555A1 (en) | 2008-12-24 | 2013-12-30 | Emd Millipore Corp | Caustic stable chromatography ligands |
| US20130243779A1 (en) | 2009-02-05 | 2013-09-19 | Intercell Ag | Peptides protective against e. faecalis, methods and uses relating thereto |
| BRPI1011856A2 (pt) * | 2009-03-23 | 2020-11-03 | Epitopix, Llc | polipeptídeos e composições de imunização contendo polipeptídeos gram-positivos e métodos de uso |
| HUE026855T2 (en) | 2009-04-03 | 2016-07-28 | Univ Chicago | Compositions and methods related to protein a (spa) variants |
| EP3263128A3 (en) * | 2009-04-14 | 2018-01-24 | GlaxoSmithKline Biologicals S.A. | Compositions for immunising against staphylococcus aureus |
| CA2704702C (en) * | 2009-06-02 | 2018-06-12 | Unilever Plc | Aerated baked products |
| JP5867952B2 (ja) | 2009-06-10 | 2016-02-24 | ノバルティス アーゲー | ベンゾナフチリジン含有ワクチン |
| SA110310528B1 (ar) | 2009-06-22 | 2014-07-02 | Wyeth Llc | التركيبات المولدة للمناعة لأنتيجينات ستافيلوكوكس أوريس |
| GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| WO2011027222A2 (en) | 2009-09-02 | 2011-03-10 | Novartis Ag | Immunogenic compositions including tlr activity modulators |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| BR112012014624A8 (pt) | 2009-12-15 | 2017-12-26 | Novartis Ag | suspensão homogênea de compostos de imunopotenciação e usos dos destes |
| WO2011101465A1 (en) | 2010-02-19 | 2011-08-25 | Intercell Ag | Ic31 nanoparticles |
| EA031379B1 (ru) | 2010-03-23 | 2018-12-28 | Новартис Аг | Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний |
| EP2555794A4 (en) | 2010-04-05 | 2014-01-15 | Univ Chicago | COMPOSITIONS AND METHODS RELATING TO PROTEIN A (SPA) ANTIBODIES AS IMMUNE REACTION AMPLIFIERS |
| EP4015523A1 (en) * | 2010-05-05 | 2022-06-22 | New York University | Staphylococcus aureus leukocidins, therapeutic compositions, and uses thereof |
| CA2803298C (en) | 2010-07-02 | 2020-07-14 | The University Of Chicago | Compositions and methods related to protein a (spa) variants |
| US9192661B2 (en) | 2010-07-06 | 2015-11-24 | Novartis Ag | Delivery of self-replicating RNA using biodegradable polymer particles |
| WO2012021229A1 (en) | 2010-07-13 | 2012-02-16 | Merck Sharp & Dohme Corp. | Staphylococcus aureus surface protein sa1789 and protective vaccine based thereon |
| EP2614074A1 (en) | 2010-09-09 | 2013-07-17 | The University of Chicago | Methods and compositions involving protective staphylococcal antigens |
| EP2638058B1 (en) | 2010-11-12 | 2017-01-11 | Merck Sharp & Dohme Corp. | Enolase peptide conjugate vaccines against staphylococcus aureus |
| CN102558316B (zh) * | 2010-12-30 | 2015-07-01 | 上海雅心生物技术有限公司 | 高稳定性的具抗体结合能力的重组蛋白a及其生产 |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| US8846609B2 (en) | 2011-06-19 | 2014-09-30 | New York University | Leukotoxin E/D as a new anti-inflammatory agent and microbicide |
| NZ764564A (en) | 2011-06-19 | 2022-10-28 | Univ New York | Methods of treating and preventing staphylococcus aureus infections and associated conditions |
| US9527892B2 (en) | 2011-10-31 | 2016-12-27 | Merck Sharp & Dohme Corp. | Protective vaccine based on Staphylococcus aureus SA2451 protein |
| EP3511339B1 (en) | 2012-02-20 | 2025-04-09 | IPC Research, LLC | Polypeptides binding to human complement c5 |
| JP6670106B2 (ja) | 2012-04-26 | 2020-03-18 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | ブドウ球菌コアグラーゼ抗原およびその使用方法 |
| US9376487B2 (en) | 2012-07-10 | 2016-06-28 | Merck Sharp & Dohme Corp. | Protective vaccine based on Staphylococcus aureus SA2493 protein |
| RU2526497C2 (ru) * | 2012-10-31 | 2014-08-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Северо-Западный государственный медицинский университет им. И.И. Мечникова" Министерства здравоохарнения и социального развития Российской Федерации | Способ определения генотипов золотистого стафилококка |
| BR112015010125A2 (pt) * | 2012-11-06 | 2017-08-22 | Medimmune Llc | Anticorpo isolado ou seu fragmento de ligação, composição, ácido nucleico isolado, métodos de determinação da presença de s. aureus em uma amostra de teste, de tratamento de uma infecção por s. aureus em um paciente, de prevenção ou redução da gravidade de sepsia associada a s. aureus em um paciente, de atraso do início de sepsia associada a infecção por s. aureus em um paciente, de prevenção do início de sepsia associada a infecção por s. aureus em um paciente, de redução de carga bacteriana de s. aureus na corrente sanguínea ou coração em um paciente, e de redução da aglutinação bacteriana de s. aureus e/ou formação de lesões tromboembólicas em um paciente |
| WO2014096333A1 (en) * | 2012-12-20 | 2014-06-26 | Morphosys Ag | Anti-staphylococcal antibodies |
| CN103965336B (zh) * | 2013-01-29 | 2016-08-10 | 苏州偲聚生物材料有限公司 | 多肽、包含该多肽的检测器件和检测试剂盒 |
| BR112015018014A2 (pt) | 2013-02-01 | 2017-07-11 | Glaxosmithkline Biologicals Sa | liberação intradérmica de composições imunológicas compreendendo agonistas do receptor do tipo toll |
| US10077299B2 (en) * | 2013-04-25 | 2018-09-18 | Abtlas Co., Ltd. | Method for refining protein including self-cutting cassette and use thereof |
| MX367423B (es) | 2013-08-28 | 2019-08-21 | Affibody Ab | Polipeptidos de union a c5. |
| BR112016003142A2 (pt) * | 2013-08-28 | 2017-10-17 | Swedish Orphan Biovitrum Ab Publ | ligação de polipeptídeos estáveis ao c5 do complemento humano |
| CN104558196A (zh) * | 2013-10-15 | 2015-04-29 | 温州医科大学 | 基于HBcAg载体的沙眼衣原体主要外膜蛋白表位疫苗及其用途 |
| RU2542396C1 (ru) * | 2013-11-06 | 2015-02-20 | Федеральное бюджетное учреждение науки "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н. Габричевского" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека | Способ и набор для ускоренной лабораторной диагностики коклюшной инфекции |
| EP3077820B1 (en) * | 2013-12-03 | 2025-02-26 | Evaxion Biotech A/S | Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus |
| CN103694323B (zh) * | 2013-12-09 | 2017-01-18 | 成都欧林生物科技股份有限公司 | 金黄色葡萄球菌MntC重组蛋白及其制备方法和应用 |
| US10100093B2 (en) | 2013-12-31 | 2018-10-16 | Epitopix Llc | Polypeptides and immunizing compositions containing Burkholderia polypeptides and methods of use |
| WO2016000022A1 (en) * | 2014-06-30 | 2016-01-07 | Murdoch Childrens Research Institute | Helicobacter therapeutic |
| CN104569386B (zh) * | 2014-12-10 | 2016-05-11 | 中国水产科学研究院淡水渔业研究中心 | 一种罗非鱼源无乳链球菌elisa快速检测试剂盒及其检测方法 |
| KR20170098821A (ko) | 2014-12-17 | 2017-08-30 | 에프. 호프만-라 로슈 아게 | 소르타아제를 사용한 1 단계로의 이중 폴리펩티드 컨쥬게이션을 위한 효소 원-포트 반응 |
| JP2018517708A (ja) | 2015-06-05 | 2018-07-05 | ニューヨーク・ユニバーシティ | 抗ブドウ球菌生物学的薬剤のための組成物及び方法 |
| CN108138204B (zh) | 2015-09-25 | 2021-12-31 | 豪夫迈·罗氏有限公司 | 使用分选酶a生产硫酯的方法 |
| WO2017050866A1 (en) | 2015-09-25 | 2017-03-30 | F. Hoffmann-La Roche Ag | Novel soluble sortase a |
| CN108026560A (zh) | 2015-09-25 | 2018-05-11 | 豪夫迈·罗氏有限公司 | 在低共熔溶剂中使用分选酶的转酰胺反应 |
| PL3380508T3 (pl) | 2015-11-27 | 2021-07-12 | Masarykova Univerzita | Termostabilny polipeptyd fgf2, jego zastosowanie |
| US10166280B2 (en) | 2016-06-08 | 2019-01-01 | Epitopix, Llc | Polypeptides and immunizing compositions containing Bacillus polypeptides and methods of use |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| US10504742B2 (en) * | 2017-05-31 | 2019-12-10 | Asm Ip Holding B.V. | Method of atomic layer etching using hydrogen plasma |
| WO2018237010A2 (en) * | 2017-06-20 | 2018-12-27 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Vaccine compositions and methods of using the same |
| JP7362667B2 (ja) | 2018-02-12 | 2023-10-17 | イニミューン・コーポレーション | Toll様受容体リガンド |
| US10905738B2 (en) * | 2018-07-05 | 2021-02-02 | Biozeus Desenvolvimento De Produtos Biofarmacêuticos | Synthetic peptides, prodrugs, pharmaceutical compositions and uses |
| RU2689161C1 (ru) * | 2018-10-04 | 2019-05-24 | Федеральное бюджетное учреждение науки "Казанский научно-исследовательский институт эпидемиологии и микробиологии" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека | Способ получения бактериальных антигенов |
| US12514914B2 (en) | 2019-05-14 | 2026-01-06 | The University Of Chicago | Methods and compositions comprising Staphylococcus protein a (SpA) variants |
| CN114929750B (zh) | 2019-09-13 | 2024-11-22 | 芝加哥大学 | 用于治疗葡萄球菌感染的方法和组合物 |
| CN111110838A (zh) * | 2019-12-24 | 2020-05-08 | 华南师范大学 | 一种罗非鱼无乳链球菌疫苗及其制备方法 |
| EP4084824A1 (en) * | 2019-12-31 | 2022-11-09 | Antagonis | Compositions and methods for the prevention of s. aureus infection |
| US20230204567A1 (en) * | 2020-05-20 | 2023-06-29 | Takeda Vaccines, Inc. | Method for determining the potency of antigens |
| CN111808977B (zh) * | 2020-07-23 | 2023-06-27 | 清华大学深圳国际研究生院 | 一种由snp所引起利福平类抗生素耐药的抗性基因的特异性引物的设计方法及检测方法 |
| JP2023547677A (ja) | 2020-11-04 | 2023-11-13 | エリゴ・バイオサイエンス | キューティバクテリウム・アクネス組換えファージ、その産生方法及び使用 |
| KR102306010B1 (ko) * | 2021-04-07 | 2021-09-27 | 씨제이제일제당 (주) | 신규한 분지쇄아미노산 투과효소 변이체 및 이를 이용한 l-발린 생산 방법 |
| KR102281369B1 (ko) * | 2021-04-07 | 2021-07-22 | 씨제이제일제당 (주) | 신규한 디히드로리포일 아세틸기전이효소 변이체 및 이를 이용한 l-발린 생산 방법 |
| CN116785418A (zh) * | 2022-12-07 | 2023-09-22 | 深圳万可森生物科技有限公司 | 一种鱼源无乳链球菌亚单位疫苗及其制备方法与应用 |
| CN120028542B (zh) * | 2025-01-17 | 2025-11-25 | 宁夏医科大学 | 血清抗体IgG特异识别其疫苗株抗原谱及其筛选方法和应用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69033600T2 (de) * | 1989-03-09 | 2001-04-05 | American Cyanamid Co., Madison | Verfahren zur Isolierung von Haemopnilus influenzae Protein-E |
| US5980908A (en) * | 1991-12-05 | 1999-11-09 | Alfa Laval Ab | Bacterial cell surface protein with fibronectin, fibrinogen, collagen and laminin binding ability, process for the manufacture of the protein and prophylactic treatment |
| US5456907A (en) | 1992-01-10 | 1995-10-10 | Helene Curtis, Inc. | Cysteamine permanent wave composition and method |
| WO1997014800A1 (en) * | 1995-10-16 | 1997-04-24 | Smithkline Beecham Plc | Novel saliva binding protein |
| US6737248B2 (en) * | 1996-01-05 | 2004-05-18 | Human Genome Sciences, Inc. | Staphylococcus aureus polynucleotides and sequences |
| RS50101B (sr) | 1996-02-24 | 2009-01-22 | Boehringer Ingelheim International Gmbh., | Farmaceutski preparati za imunomodulaciju |
| US6380370B1 (en) * | 1997-08-14 | 2002-04-30 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
| WO1999030151A1 (en) * | 1997-12-05 | 1999-06-17 | Intercell Biomedizinische Forschungs- Und Entwicklungs Gmbh | Method and cells to screen combinatorial libraries |
| DE19803453A1 (de) | 1998-01-30 | 1999-08-12 | Boehringer Ingelheim Int | Vakzine |
| EP1073771B1 (en) * | 1998-04-30 | 2004-12-01 | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. | New method for the selection of clones of an expression library involving rearraying |
| EP1090111A1 (en) * | 1998-06-25 | 2001-04-11 | Institut Pasteur | Exhaustive analysis of viral protein interactions by two-hybrid screens and selection of correctly folded viral interacting polypeptides |
| US6610836B1 (en) * | 1999-01-29 | 2003-08-26 | Genome Therapeutics Corporation | Nucleic acid amino acid sequences relating to Klebsiella pneumoniae for diagnostics and therapeutics |
| AT407643B (de) * | 1999-02-01 | 2001-05-25 | Intercell Biomedizinische Forschungs & Entwicklungs Gmbh | Verfahren zur selektion und herstellung von vakzin- und diagnostika-präparationen |
| US6936258B1 (en) * | 1999-03-19 | 2005-08-30 | Nabi Biopharmaceuticals | Staphylococcus antigen and vaccine |
| ATE320486T1 (de) * | 1999-05-05 | 2006-04-15 | Phylogica Ltd | Isolierung von biologischen modulatoren aus bibiotheken mit biologisch vielfältigen genfragmenten |
| MXPA01012787A (es) * | 1999-08-06 | 2005-08-26 | Ivigene Corp | Polinucleotidos microbianos expresados durante la infeccion de un huesped.. |
| AT408721B (de) | 1999-10-01 | 2002-02-25 | Cistem Biotechnologies Gmbh | Pharmazeutische zusammensetzung enthaltend ein antigen |
| CA2404260A1 (en) | 2000-03-21 | 2001-09-27 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in prokaryotes |
| RU2413520C2 (ru) | 2000-06-08 | 2011-03-10 | Интерселл Аг | Вакцинная композиция, содержащая иммуностимулирующие олигодезоксинуклеотиды |
| GB0014907D0 (en) * | 2000-06-20 | 2000-08-09 | Univ Sheffield | Antigenic polypeptides |
| CA2418854A1 (en) | 2000-08-17 | 2002-02-21 | Jorg Fritz | A vaccine which comprises at least one antigen and a cathelididin derived antimicrobial peptide or a derivative thereof |
| AT410635B (de) | 2000-10-18 | 2003-06-25 | Cistem Biotechnologies Gmbh | Vakzin-zusammensetzung |
| AT410798B (de) | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| AU2002306849A1 (en) | 2001-03-21 | 2002-10-08 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in microorganisms |
| GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| MXPA03011701A (es) | 2001-06-15 | 2004-12-06 | Nhibitex Inc | Anticuerpos monoclonales y policlonales de reaccion que reconocen las proteinas de superficie a partir de estafilococos coagulasa-negativos y staphylococcus aureus. |
| ATE542829T1 (de) | 2001-08-02 | 2012-02-15 | Univ Sheffield | Impfstoff |
| KR20060065643A (ko) | 2003-07-24 | 2006-06-14 | 머크 앤드 캄파니 인코포레이티드 | 스타필로코쿠스 아우레우스에 대한 방어 면역 반응을유도하는 폴리펩타이드 |
| DE602005010225D1 (de) | 2005-06-13 | 2008-11-20 | Research In Motion Ltd | Elektrischer Verbinder und elektrisches System für ein Bauteil in einem elektronischen Gerät |
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