DK1399559T4 - Muse-lambda-letkædelocus - Google Patents

Muse-lambda-letkædelocus Download PDF

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Publication number
DK1399559T4
DK1399559T4 DK02732970.5T DK02732970T DK1399559T4 DK 1399559 T4 DK1399559 T4 DK 1399559T4 DK 02732970 T DK02732970 T DK 02732970T DK 1399559 T4 DK1399559 T4 DK 1399559T4
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DK
Denmark
Prior art keywords
mouse
chain
mice
cells
cell
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Application number
DK02732970.5T
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English (en)
Other versions
DK1399559T3 (da
Inventor
Marianne Bruggemann
Xiangang Zou
Original Assignee
Crescendo Biolog Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9917128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1399559(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Crescendo Biolog Ltd filed Critical Crescendo Biolog Ltd
Publication of DK1399559T3 publication Critical patent/DK1399559T3/da
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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/054—Animals comprising random inserted nucleic acids (transgenic) inducing loss of function
    • A01K2217/058—Animals comprising random inserted nucleic acids (transgenic) inducing loss of function due to expression of inhibitory nucleic acid, e.g. siRNA, antisense
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Position Input By Displaying (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Details Of Television Scanning (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • User Interface Of Digital Computer (AREA)
DK02732970.5T 2001-06-21 2002-06-21 Muse-lambda-letkædelocus DK1399559T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0115256.0A GB0115256D0 (en) 2001-06-21 2001-06-21 Mouse light chain locus
PCT/GB2002/002867 WO2003000737A2 (en) 2001-06-21 2002-06-21 MOUSE μ LIGHT CHAIN LOCUS

Publications (2)

Publication Number Publication Date
DK1399559T3 DK1399559T3 (da) 2008-08-25
DK1399559T4 true DK1399559T4 (da) 2015-12-14

Family

ID=9917128

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02732970.5T DK1399559T4 (da) 2001-06-21 2002-06-21 Muse-lambda-letkædelocus

Country Status (11)

Country Link
US (4) US7541513B2 (da)
EP (2) EP1399559B2 (da)
AT (1) ATE393826T1 (da)
AU (1) AU2002304460A1 (da)
CY (1) CY1108227T1 (da)
DE (1) DE60226322T3 (da)
DK (1) DK1399559T4 (da)
ES (1) ES2305245T5 (da)
GB (2) GB0115256D0 (da)
PT (1) PT1399559E (da)
WO (1) WO2003000737A2 (da)

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Also Published As

Publication number Publication date
WO2003000737A2 (en) 2003-01-03
GB2392672A (en) 2004-03-10
US20050060763A1 (en) 2005-03-17
DE60226322D1 (de) 2008-06-12
DK1399559T3 (da) 2008-08-25
US8367888B2 (en) 2013-02-05
ES2305245T5 (es) 2015-12-11
US10194645B2 (en) 2019-02-05
US20110093961A1 (en) 2011-04-21
GB0400676D0 (en) 2004-02-18
EP1956092A1 (en) 2008-08-13
GB2392672B (en) 2005-05-11
US9439405B2 (en) 2016-09-13
DE60226322T3 (de) 2016-03-03
AU2002304460A1 (en) 2003-01-08
WO2003000737A3 (en) 2003-09-25
ES2305245T3 (es) 2008-11-01
EP1399559B2 (en) 2015-09-02
EP1399559B1 (en) 2008-04-30
ATE393826T1 (de) 2008-05-15
GB0115256D0 (en) 2001-08-15
EP1399559A2 (en) 2004-03-24
US20170049083A1 (en) 2017-02-23
CY1108227T1 (el) 2014-02-12
US20130046079A1 (en) 2013-02-21
DE60226322T2 (de) 2009-07-09
US7541513B2 (en) 2009-06-02
PT1399559E (pt) 2008-07-29

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