DK1406865T3 - Ravsyrederivater - Google Patents

Ravsyrederivater

Info

Publication number
DK1406865T3
DK1406865T3 DK02738174T DK02738174T DK1406865T3 DK 1406865 T3 DK1406865 T3 DK 1406865T3 DK 02738174 T DK02738174 T DK 02738174T DK 02738174 T DK02738174 T DK 02738174T DK 1406865 T3 DK1406865 T3 DK 1406865T3
Authority
DK
Denmark
Prior art keywords
succinic acid
acid derivatives
pharmaceutical compositions
compounds
processes
Prior art date
Application number
DK02738174T
Other languages
Danish (da)
English (en)
Inventor
Thomas Roelle
Markus Albers
Gerhard Hessler
Karl Ziegelbauer
Kevin Bacon
Hiromi Okigami
Ruediger Fischer
Thomas Lehmann
Gerhard Mueller
Masaomi Tajimi
Haruki Hasegawa
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Application granted granted Critical
Publication of DK1406865T3 publication Critical patent/DK1406865T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/55—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK02738174T 2001-07-06 2002-06-24 Ravsyrederivater DK1406865T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0116577A GB2377933A (en) 2001-07-06 2001-07-06 Succinic acid derivatives useful as integrin antagonists

Publications (1)

Publication Number Publication Date
DK1406865T3 true DK1406865T3 (da) 2006-05-08

Family

ID=9918063

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02738174T DK1406865T3 (da) 2001-07-06 2002-06-24 Ravsyrederivater

Country Status (9)

Country Link
US (1) US7064229B2 (fr)
EP (1) EP1406865B1 (fr)
AT (1) ATE317380T1 (fr)
DE (1) DE60209122T2 (fr)
DK (1) DK1406865T3 (fr)
ES (1) ES2258636T3 (fr)
GB (1) GB2377933A (fr)
PT (1) PT1406865E (fr)
WO (1) WO2003004460A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2430978C (fr) 2000-12-28 2012-05-15 Daiichi Pharmaceutical Co., Ltd. Inhibiteurs de vla-4
CA2492035A1 (fr) 2002-07-11 2004-01-15 Vicuron Pharmaceuticals, Inc. Derives de n-hydroxyamide ayant une activite anti-bacterienne
JP4676884B2 (ja) 2003-07-24 2011-04-27 第一三共株式会社 シクロヘキサンカルボン酸類
SG176628A1 (en) 2009-06-05 2012-01-30 Link Medicine Corp Aminopyrrolidinone derivatives and uses thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT205017B (de) * 1956-12-20 1959-08-25 Lannacher Heilmittel Verfahern zur Herstellung neuer, substituierter Halbamide der Bernsteinsäure
US4482572A (en) * 1983-05-05 1984-11-13 Smithkline Beckman Corporation 1-Acylamino-1-cyclopentanecarboxylic acids
DE3535247A1 (de) * 1985-10-03 1987-04-09 Agfa Gevaert Ag Farbfotografisches aufzeichnungsmaterial mit leicht dispergierbaren farbkupplern
US6306840B1 (en) 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
JP2000516596A (ja) * 1996-07-25 2000-12-12 バイオジェン,インコーポレイテッド 細胞接着インヒビター
AU1361499A (en) 1997-10-21 1999-05-10 Merck & Co., Inc. Azapeptide acids as cell adhesion inhibitors
WO1999026923A1 (fr) 1997-11-20 1999-06-03 Merck & Co., Inc. Derives de carboxamide de para-aminomethylaryl
SK9372000A3 (en) 1997-12-23 2002-03-05 Rhone Poulenc Rorer Ltd Substituted beta-alanines
CN1294576A (zh) 1998-01-23 2001-05-09 诺瓦提斯公司 Vla-4拮抗剂
JP3676677B2 (ja) 1998-06-30 2005-07-27 ファイザー・プロダクツ・インク 炎症性疾患、自己免疫疾患および呼吸疾患の治療において有用なvla−4依存性細胞結合の非ペプチジル阻害薬
DE19962936A1 (de) 1999-12-24 2001-06-28 Bayer Ag Neue beta-Aminosäureverbindungen als Integrinantagonisten
DE10006453A1 (de) 2000-02-14 2001-08-16 Bayer Ag Piperidylcarbonsäuren als Integrinantagonisten
DE10019755A1 (de) 2000-04-20 2001-11-08 Bayer Ag Neue Aminoaryl/cycloalkylcarbonsäuren als Integrinantagonisten
GB2367816A (en) * 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
GB2369357A (en) 2000-10-09 2002-05-29 Bayer Ag Aliphatic, cyclic amino carboxylic acids as integrin antagonists
GB2367817A (en) 2000-10-09 2002-04-17 Bayer Ag Cyclic carboxylic acids as integrin antagonists

Also Published As

Publication number Publication date
DE60209122T2 (de) 2006-08-03
GB0116577D0 (en) 2001-08-29
ES2258636T3 (es) 2006-09-01
DE60209122D1 (de) 2006-04-20
PT1406865E (pt) 2006-06-30
WO2003004460A3 (fr) 2003-12-11
US20040254157A1 (en) 2004-12-16
WO2003004460A2 (fr) 2003-01-16
GB2377933A (en) 2003-01-29
EP1406865A2 (fr) 2004-04-14
US7064229B2 (en) 2006-06-20
EP1406865B1 (fr) 2006-02-08
ATE317380T1 (de) 2006-02-15

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