DK146578A - Fremgangsmaade til fremstilling af interphenylen 8-aza-9-dioxothia-11%12-secoprostaglandiner - Google Patents
Fremgangsmaade til fremstilling af interphenylen 8-aza-9-dioxothia-11%12-secoprostaglandinerInfo
- Publication number
- DK146578A DK146578A DK146578A DK146578A DK146578A DK 146578 A DK146578 A DK 146578A DK 146578 A DK146578 A DK 146578A DK 146578 A DK146578 A DK 146578A DK 146578 A DK146578 A DK 146578A
- Authority
- DK
- Denmark
- Prior art keywords
- secoprostaglandins
- dioxothia
- interphenylene
- aza
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/783,998 US4112236A (en) | 1977-04-04 | 1977-04-04 | Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK146578A true DK146578A (da) | 1978-10-05 |
Family
ID=25131052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK146578A DK146578A (da) | 1977-04-04 | 1978-04-03 | Fremgangsmaade til fremstilling af interphenylen 8-aza-9-dioxothia-11%12-secoprostaglandiner |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4112236A (da) |
| AR (1) | AR225727A1 (da) |
| AU (1) | AU516540B2 (da) |
| BE (1) | BE865624A (da) |
| DE (1) | DE2814321A1 (da) |
| DK (1) | DK146578A (da) |
| ES (1) | ES468510A1 (da) |
| FR (1) | FR2386521A1 (da) |
| GB (1) | GB1576688A (da) |
| IE (1) | IE46699B1 (da) |
| IT (1) | IT1103475B (da) |
| LU (1) | LU79356A1 (da) |
| NL (1) | NL7802824A (da) |
| PT (1) | PT67847B (da) |
| SE (1) | SE7803606L (da) |
| ZA (1) | ZA781885B (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2809377A1 (de) * | 1978-03-04 | 1979-09-13 | Boehringer Mannheim Gmbh | Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| DE3000377A1 (de) * | 1980-01-07 | 1981-07-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| DE3641099A1 (de) * | 1986-12-02 | 1988-06-09 | Hoechst Ag | Verfahren zur herstellung von 4-(2'-chlorethyl)benzoesaeure |
| WO1998027976A1 (en) * | 1996-12-20 | 1998-07-02 | Pfizer Inc. | Prevention and treatment of skeletal disorder with ep2 receptor subtype selective prostaglandin e2 agonists |
| UA59384C2 (uk) * | 1996-12-20 | 2003-09-15 | Пфайзер, Інк. | Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі |
| UA67754C2 (uk) | 1997-10-10 | 2004-07-15 | Пфайзер, Інк. | Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти) |
| US6124314A (en) * | 1997-10-10 | 2000-09-26 | Pfizer Inc. | Osteoporosis compounds |
| PT1132086E (pt) | 2000-01-31 | 2006-09-29 | Pfizer Prod Inc | Utilizacao de agonistas selectivos para o receptor da prostaglandina (pge2) 4 (ep4) para o tratamento de falha renal aguda e cronica |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6903105B2 (en) | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| MX2015007797A (es) | 2012-12-17 | 2015-10-05 | Parion Sciences Inc | Compuestos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil) carbamimidoil) pirazin-2-carboxamida. |
| PE20151054A1 (es) | 2012-12-17 | 2015-08-07 | Parion Sciences Inc | Derivados de cloro-pirazin carboxamida con actividad bloqueadora sobre los canales de sodio epiteliales |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE410185B (sv) | 1973-04-25 | 1979-10-01 | Merck & Co Inc | Forfarande for framstellning av seko - prostaglandiner med vasodilaterande och blodplettaggregationshemmande effekt |
| US3991106A (en) * | 1974-09-13 | 1976-11-09 | Merck & Co., Inc. | 16-Ethers of 8-aza-9-dioxothia-11,12-seco-prostaglandins |
-
1977
- 1977-04-04 US US05/783,998 patent/US4112236A/en not_active Expired - Lifetime
-
1978
- 1978-03-15 NL NL7802824A patent/NL7802824A/xx not_active Application Discontinuation
- 1978-03-21 AU AU34366/78A patent/AU516540B2/en not_active Expired
- 1978-03-21 AR AR271490A patent/AR225727A1/es active
- 1978-03-28 IT IT48626/78A patent/IT1103475B/it active
- 1978-03-30 SE SE7803606A patent/SE7803606L/xx unknown
- 1978-03-30 PT PT67847A patent/PT67847B/pt unknown
- 1978-03-30 IE IE632/78A patent/IE46699B1/en unknown
- 1978-03-30 FR FR7809266A patent/FR2386521A1/fr active Granted
- 1978-03-31 GB GB12700/78A patent/GB1576688A/en not_active Expired
- 1978-04-03 DE DE19782814321 patent/DE2814321A1/de not_active Withdrawn
- 1978-04-03 ES ES468510A patent/ES468510A1/es not_active Expired
- 1978-04-03 BE BE186514A patent/BE865624A/xx not_active IP Right Cessation
- 1978-04-03 ZA ZA00781885A patent/ZA781885B/xx unknown
- 1978-04-03 LU LU79356A patent/LU79356A1/xx unknown
- 1978-04-03 DK DK146578A patent/DK146578A/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB1576688A (en) | 1980-10-15 |
| FR2386521B1 (da) | 1982-11-19 |
| IE780632L (en) | 1978-10-04 |
| LU79356A1 (fr) | 1978-11-27 |
| BE865624A (fr) | 1978-10-03 |
| IE46699B1 (en) | 1983-08-24 |
| IT1103475B (it) | 1985-10-14 |
| SE7803606L (sv) | 1978-10-05 |
| IT7848626A0 (it) | 1978-03-28 |
| ZA781885B (en) | 1979-06-27 |
| ES468510A1 (es) | 1979-09-16 |
| AU3436678A (en) | 1979-09-27 |
| PT67847B (en) | 1980-04-04 |
| FR2386521A1 (fr) | 1978-11-03 |
| DE2814321A1 (de) | 1978-10-05 |
| US4112236A (en) | 1978-09-05 |
| AU516540B2 (en) | 1981-06-11 |
| AR225727A1 (es) | 1982-04-30 |
| PT67847A (en) | 1978-04-01 |
| NL7802824A (nl) | 1978-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |