DK1465923T3 - Corticotroprinafgivende faktor 2-receptoragonister - Google Patents

Corticotroprinafgivende faktor 2-receptoragonister

Info

Publication number
DK1465923T3
DK1465923T3 DK03731965T DK03731965T DK1465923T3 DK 1465923 T3 DK1465923 T3 DK 1465923T3 DK 03731965 T DK03731965 T DK 03731965T DK 03731965 T DK03731965 T DK 03731965T DK 1465923 T3 DK1465923 T3 DK 1465923T3
Authority
DK
Denmark
Prior art keywords
corticotroprine
receptor agonists
releasing factor
releasing
factor
Prior art date
Application number
DK03731965T
Other languages
English (en)
Inventor
Robert Joseph Isfort
Wieslaw Adam Mazur
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Application granted granted Critical
Publication of DK1465923T3 publication Critical patent/DK1465923T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK03731965T 2002-01-16 2003-01-16 Corticotroprinafgivende faktor 2-receptoragonister DK1465923T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US34911702P 2002-01-16 2002-01-16
US37633702P 2002-04-29 2002-04-29
US38889502P 2002-06-14 2002-06-14
US41198802P 2002-09-19 2002-09-19
PCT/US2003/001454 WO2003062277A1 (en) 2002-01-16 2003-01-16 Corticotropin releasing factor receptor 2 agonists

Publications (1)

Publication Number Publication Date
DK1465923T3 true DK1465923T3 (da) 2007-07-02

Family

ID=27617822

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03703867T DK1465921T3 (da) 2002-01-16 2003-01-16 Agonister til corticotropinfrigörelsesfaktor receptor-2
DK03731965T DK1465923T3 (da) 2002-01-16 2003-01-16 Corticotroprinafgivende faktor 2-receptoragonister

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK03703867T DK1465921T3 (da) 2002-01-16 2003-01-16 Agonister til corticotropinfrigörelsesfaktor receptor-2

Country Status (29)

Country Link
US (7) US7192923B2 (da)
EP (4) EP1724283B1 (da)
JP (3) JP4489434B2 (da)
KR (3) KR100758857B1 (da)
CN (3) CN1617887A (da)
AR (3) AR038142A1 (da)
AT (4) ATE334147T1 (da)
AU (2) AU2003205197B2 (da)
BR (3) BR0306826A (da)
CA (3) CA2470731C (da)
CY (1) CY1106133T1 (da)
DE (4) DE60313845T2 (da)
DK (2) DK1465921T3 (da)
ES (4) ES2309909T3 (da)
IL (5) IL162431A0 (da)
MA (3) MA27590A1 (da)
MX (3) MXPA04006884A (da)
MY (1) MY140306A (da)
NO (3) NO20043366L (da)
NZ (3) NZ533599A (da)
PE (3) PE20030849A1 (da)
PL (3) PL371364A1 (da)
PT (2) PT1465923E (da)
RU (1) RU2294333C2 (da)
SA (3) SA03230564B1 (da)
SI (1) SI1465921T1 (da)
TW (3) TW200302278A (da)
WO (3) WO2003062277A1 (da)
ZA (1) ZA200404995B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001289916A1 (en) * 2000-09-22 2002-04-02 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Methods for improving the antagonistic/agonistic properties of peptidic antagonists/agonists of the corticotropin-releasing factor receptor (crfr)
US7192923B2 (en) * 2002-01-16 2007-03-20 The Procter & Gamble Company Corticotropin releasing factor 2 receptor agonists
WO2005103690A2 (en) * 2004-04-24 2005-11-03 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with corticotropin releasing hormone receptor 2 (crhr2)
AU2006235045A1 (en) * 2005-03-30 2006-10-19 J. Craig Venter Institute, Inc. Haemophilus influenzae type b
WO2007090087A2 (en) * 2006-01-27 2007-08-09 Research Development Foundation Use of corticotropin releasing factor receptor-2 inhibitors for treating insulin-related diseases
AU2008303893A1 (en) * 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of adrenomedullin as a therapeutic agent for the treatment of excessive angiogenesis
WO2009043469A2 (en) * 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Use of pneumadin as a therapeutic agent
WO2009046874A1 (en) * 2007-09-11 2009-04-16 Mondobiotech Laboratories Ag Therapeutic combination of trh-potentiating peptide and stresscopin
BRPI0921640A2 (pt) * 2008-11-04 2019-09-24 Janssen Pharmaceutica Nv agonistas peptídicos do crhr2 e usos do mesmo
EP2206726A1 (en) * 2009-01-08 2010-07-14 Universite Joseph Fourier Non-invasive tools for detecting vulnerable atherosclerotic plaques
KR20120103606A (ko) * 2009-11-04 2012-09-19 얀센 파마슈티카 엔.브이. 스트레스코핀-유사 펩타이드를 이용해 심부전을 치료하는 방법
WO2013063046A1 (en) 2011-10-24 2013-05-02 Research Development Foundation Methods for increasing insulin secretion by co-stimulation of corticotropin-releasing factor receptors
JP6562632B2 (ja) * 2012-02-14 2019-08-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 心血管疾患および他の状態のためのパラクリン遺伝子の全身送達および制御された発現
JOP20170153A1 (ar) * 2016-07-15 2019-01-30 Lilly Co Eli نظائر urocortin-2 جديدة معدلة بحمض دهني لعلاج داء السكري وأمراض الكلى المزمنة
KR20190084055A (ko) 2016-10-20 2019-07-15 코르텐 인코포레이티드 부적응 스트레스 반응에서 기인한 질환의 치료 방법
CN110755434B (zh) * 2018-07-27 2022-03-15 中国医学科学院药物研究所 化合物palosuran防治骨骼肌萎缩等疾病的用途
WO2025184558A1 (en) * 2024-02-28 2025-09-04 Caradon Therapeutics, Inc. Modified urocortin 3
TW202544027A (zh) * 2024-04-19 2025-11-16 美商紐羅克里生物科學有限公司 促皮質素釋放因子受體2(crfr2)促效劑
WO2025230248A1 (ko) * 2024-04-30 2025-11-06 한미약품 주식회사 Crf2 수용체 작용제와 그 아실화 결합체의 용도
WO2026139062A1 (zh) * 2024-12-26 2026-07-02 杭州先为达生物科技股份有限公司 促肾上腺皮质激素释放因子2受体激动剂及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235036A (en) 1991-05-31 1993-08-10 The Salk Institute For Biological Studies Crf analogs
US5786203A (en) 1994-06-14 1998-07-28 Neurocrine Biosciences, Inc. Isolated nucleic acid encoding corticotropin-releasing factor2 receptors
EP0860501A3 (en) 1994-06-14 1999-05-19 Neurocrine Biosciences, Inc. Corticotropin-releasing factor2 receptors
US5824771A (en) * 1994-12-12 1998-10-20 The Salk Institute For Biological Studies Cyclic CRF agonists
US5663292A (en) * 1994-12-12 1997-09-02 The Salk Institute For Biological Studies Cyclic CRF analogs
US5660824A (en) 1995-05-24 1997-08-26 Grabstein; Kenneth H. Muscle trophic factor
AU6277796A (en) 1995-06-13 1997-01-15 Salk Institute For Biological Studies, The Urocortin peptides
US5869450A (en) 1996-03-06 1999-02-09 The Regents Of The University Of California Anti-inflammatory compositions and method with corticotropin-releasing factor analogs
ATE408622T1 (de) 2000-08-04 2008-10-15 Res Dev Foundation Urocortinproteine und deren verwendungen
AU2001289916A1 (en) * 2000-09-22 2002-04-02 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Methods for improving the antagonistic/agonistic properties of peptidic antagonists/agonists of the corticotropin-releasing factor receptor (crfr)
US20020082409A1 (en) 2000-10-26 2002-06-27 Hsu Sheau Yu Stresscopins and their uses
US6670140B2 (en) * 2001-03-06 2003-12-30 The Procter & Gamble Company Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
US7192923B2 (en) * 2002-01-16 2007-03-20 The Procter & Gamble Company Corticotropin releasing factor 2 receptor agonists

Also Published As

Publication number Publication date
CN1617887A (zh) 2005-05-18
AR038143A1 (es) 2004-12-29
RU2004124847A (ru) 2005-04-20
EP1465922B1 (en) 2008-01-09
AU2003237419B2 (en) 2006-04-13
NZ533599A (en) 2007-03-30
US7192924B2 (en) 2007-03-20
RU2294333C2 (ru) 2007-02-27
TW200302278A (en) 2003-08-01
SA03230564B1 (ar) 2006-10-31
EP1465923B1 (en) 2007-05-16
HK1078095A1 (zh) 2006-03-03
PE20030849A1 (es) 2003-12-01
NO20043371L (no) 2004-10-06
MXPA04006884A (es) 2004-12-06
SI1465921T1 (sl) 2006-10-31
US20030148958A1 (en) 2003-08-07
KR20040082389A (ko) 2004-09-24
SA03230565B1 (ar) 2006-10-31
PL373139A1 (en) 2005-08-22
AR038144A1 (es) 2004-12-29
BR0306838A (pt) 2005-04-05
MXPA04006885A (es) 2004-12-06
EP1465923A1 (en) 2004-10-13
CN1617885A (zh) 2005-05-18
KR100758858B1 (ko) 2007-09-14
CA2470731C (en) 2011-06-21
CA2470731A1 (en) 2003-07-31
KR100735586B1 (ko) 2007-07-04
JP2005525101A (ja) 2005-08-25
TW200302277A (en) 2003-08-01
JP2005521387A (ja) 2005-07-21
DE60318547T2 (de) 2008-12-24
NZ533598A (en) 2007-03-30
IL197774A0 (en) 2009-12-24
KR20040082390A (ko) 2004-09-24
DE60321730D1 (de) 2008-07-31
WO2003062268A2 (en) 2003-07-31
ES2309909T3 (es) 2008-12-16
PT1465921E (pt) 2006-12-29
AR038142A1 (es) 2004-12-29
ZA200404995B (en) 2005-06-29
WO2003062269A3 (en) 2003-11-06
IL162529A0 (en) 2005-11-20
US7897731B2 (en) 2011-03-01
US20030148957A1 (en) 2003-08-07
MXPA04006883A (es) 2004-12-06
DE60318547D1 (de) 2008-02-21
EP1465921B1 (en) 2006-07-26
PT1465923E (pt) 2007-08-06
SA03230564A (ar) 2005-12-03
MY140306A (en) 2009-12-31
ES2299701T3 (es) 2008-06-01
ATE362488T1 (de) 2007-06-15
IL196384A0 (en) 2011-07-31
EP1465922A2 (en) 2004-10-13
DK1465921T3 (da) 2006-11-27
KR20040082392A (ko) 2004-09-24
CA2470743C (en) 2011-12-13
ES2269976T3 (es) 2007-04-01
WO2003062268A3 (en) 2003-11-27
US20090124793A1 (en) 2009-05-14
CN100391972C (zh) 2008-06-04
JP4508649B2 (ja) 2010-07-21
US7632933B2 (en) 2009-12-15
US7192923B2 (en) 2007-03-20
WO2003062269A2 (en) 2003-07-31
IL162530A0 (en) 2005-11-20
TW200302276A (en) 2003-08-01
US20100197579A1 (en) 2010-08-05
JP4508648B2 (ja) 2010-07-21
CN100475844C (zh) 2009-04-08
ES2287484T3 (es) 2007-12-16
PL371364A1 (en) 2005-06-13
DE60307044D1 (de) 2006-09-07
US6936585B2 (en) 2005-08-30
EP1724283B1 (en) 2008-06-18
CA2470656C (en) 2011-06-28
EP1724283A2 (en) 2006-11-22
US7462597B2 (en) 2008-12-09
DE60313845T2 (de) 2008-01-31
TWI300442B (en) 2008-09-01
CA2470656A1 (en) 2003-07-31
EP1724283A3 (en) 2007-04-11
BR0306826A (pt) 2005-09-06
ATE383372T1 (de) 2008-01-15
PE20030974A1 (es) 2003-12-26
MA27592A1 (fr) 2005-11-01
DE60307044T2 (de) 2007-02-15
US20060025339A1 (en) 2006-02-02
PE20030747A1 (es) 2003-10-23
CN1617886A (zh) 2005-05-18
US7608701B2 (en) 2009-10-27
US20030148956A1 (en) 2003-08-07
JP4489434B2 (ja) 2010-06-23
WO2003062277A1 (en) 2003-07-31
US20080004435A1 (en) 2008-01-03
BR0306878A (pt) 2004-10-26
ATE398632T1 (de) 2008-07-15
ATE334147T1 (de) 2006-08-15
DE60313845D1 (de) 2007-06-28
AU2003205197B2 (en) 2006-03-02
EP1465921A2 (en) 2004-10-13
JP2005522191A (ja) 2005-07-28
SA03230565A (ar) 2005-12-03
MA27590A1 (fr) 2005-11-01
NO20043396L (no) 2004-10-06
NZ533600A (en) 2007-02-23
PL373529A1 (en) 2005-09-05
KR100758857B1 (ko) 2007-09-14
IL162431A0 (en) 2005-11-20
NO20043366L (no) 2004-10-06
CA2470743A1 (en) 2003-07-31
MA27591A1 (fr) 2005-11-01
CY1106133T1 (el) 2011-06-08

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