DK1489082T3 - Mellemprodukter - Google Patents

Mellemprodukter

Info

Publication number
DK1489082T3
DK1489082T3 DK04022638.3T DK04022638T DK1489082T3 DK 1489082 T3 DK1489082 T3 DK 1489082T3 DK 04022638 T DK04022638 T DK 04022638T DK 1489082 T3 DK1489082 T3 DK 1489082T3
Authority
DK
Denmark
Prior art keywords
intermediates
paraherquamides
present
invention includes
includes various
Prior art date
Application number
DK04022638.3T
Other languages
English (en)
Inventor
Byung H Lee
Michael F Clothier
Original Assignee
Zoetis P & U Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21695455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1489082(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zoetis P & U Llc filed Critical Zoetis P & U Llc
Application granted granted Critical
Publication of DK1489082T3 publication Critical patent/DK1489082T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Epoxy Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK04022638.3T 1995-07-21 1996-06-26 Mellemprodukter DK1489082T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US132495P 1995-07-21 1995-07-21
EP03023859A EP1400523A3 (en) 1995-07-21 1996-06-26 Intermediate compounds

Publications (1)

Publication Number Publication Date
DK1489082T3 true DK1489082T3 (da) 2013-12-09

Family

ID=21695455

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96922529T DK0871631T3 (da) 1995-07-21 1996-06-26 Antiparasitære marcfortiner og paraherquamider
DK04022638.3T DK1489082T3 (da) 1995-07-21 1996-06-26 Mellemprodukter

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK96922529T DK0871631T3 (da) 1995-07-21 1996-06-26 Antiparasitære marcfortiner og paraherquamider

Country Status (30)

Country Link
US (2) US5703078A (da)
EP (3) EP1489082B1 (da)
JP (2) JP4122447B2 (da)
KR (1) KR100428335B1 (da)
CN (2) CN1125824C (da)
AR (10) AR003466A1 (da)
AT (1) ATE311390T1 (da)
AU (1) AU699644B2 (da)
BR (7) BR9612972B8 (da)
CA (1) CA2225813C (da)
CO (1) CO4750664A1 (da)
CZ (1) CZ296008B6 (da)
DE (1) DE69635524T2 (da)
DK (2) DK0871631T3 (da)
ES (2) ES2439569T3 (da)
FI (2) FI115912B (da)
HU (1) HU226296B1 (da)
ID (1) ID30373A (da)
MX (1) MX9800625A (da)
MY (1) MY113806A (da)
NO (1) NO324287B1 (da)
NZ (1) NZ311952A (da)
PL (1) PL185007B1 (da)
PT (1) PT1489082E (da)
RU (1) RU2162090C2 (da)
SI (1) SI0871631T1 (da)
SK (2) SK284833B6 (da)
TW (1) TW334436B (da)
WO (1) WO1997003988A1 (da)
ZA (1) ZA965908B (da)

Families Citing this family (45)

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ZA976761B (en) * 1996-09-09 1999-01-29 Upjohn Co 25 Methylene and 24,25-epoxy marcfortines and paraherquamides
WO1998021211A1 (en) * 1996-11-15 1998-05-22 Pharmacia & Upjohn Company 1- and 2-substituted marcfortines and paraherquamides as antiparasitic agents
PE20011289A1 (es) * 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
AR074024A1 (es) 2008-11-14 2010-12-15 Merial Ltd Compuesto de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, composicion plaguicida y su uso para prevenir la infeccion parasitaria
MY155497A (en) 2008-11-19 2015-10-30 Merial Inc Compositions comprising an aryl pyrazole and/or a formamidine, methods and use thereof
JP5595412B2 (ja) 2008-12-04 2014-09-24 メリアル リミテッド 二量体アベルメクチン及びミルベマイシン誘導体
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
CN102712583B (zh) 2009-12-04 2015-04-08 梅里亚有限公司 农药用双-有机硫化合物
RS54772B1 (sr) 2009-12-17 2016-10-31 Merial Sas Antiparazitska jedinjenja dihidroazola i kompozicije koje ih sadrže
BR112012014933B1 (pt) 2009-12-17 2020-10-27 Merial, Inc. composições que compreendem compostos lactonas macrocíclicas e spirodioxepinoindóis
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
US8822528B2 (en) 2010-11-16 2014-09-02 Merial Limited Monensin derivatives for the treatment and prevention of protozoal infections
ES2618813T3 (es) 2011-06-27 2017-06-22 Merial, Inc. Compuestos y composiciones de éter amido-piridílico y uso contra los parásitos
US20120329832A1 (en) 2011-06-27 2012-12-27 Jean Delaveau Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
RS58417B1 (sr) 2011-09-12 2019-04-30 Merial Inc Paraziticidne kompozicije koje sadrže izoksazolinsko aktivno sredstvo, postupci i upotrebe povezane sa njima
WO2013044118A2 (en) 2011-09-23 2013-03-28 Merial Limited Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
AU2012340351B2 (en) 2011-11-17 2017-06-15 Boehringer Ingelheim Animal Health USA Inc. Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof
BR112014013371B1 (pt) 2011-12-02 2020-04-07 Merial Ltd formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina
EP3216448B8 (en) 2012-02-06 2019-06-05 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
BR122015032741B1 (pt) 2012-04-20 2019-11-26 Merial Ltd composições parasiticídicas compreendendo derivados de benzimidazol, métodos e seus usos
JP5737255B2 (ja) * 2012-09-27 2015-06-17 ダイキン工業株式会社 チオノカルボン酸エステルの製造方法
NZ723198A (en) 2012-11-20 2018-11-30 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic compounds and compositions and methods of using thereof
WO2015066277A1 (en) 2013-11-01 2015-05-07 Merial Limited Antiparisitic and pesticidal isoxazoline compounds
EP3131398B1 (en) 2014-04-17 2019-10-23 Boehringer Ingelheim Animal Health USA Inc. Use of malononitrile compounds for protecting animals from parasites
ES2842592T3 (es) 2014-05-19 2021-07-14 Boehringer Ingelheim Animal Health Usa Inc Compuestos antihelmínticos
EP3157912B1 (en) 2014-06-19 2019-02-20 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
US10864193B2 (en) 2014-10-31 2020-12-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising fipronil at high concentrations
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
LT3298027T (lt) 2015-05-20 2021-08-10 Boehringer Ingelheim Animal Health USA Inc. Antihelmintiniai depsipeptido junginiai
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
WO2018071535A1 (en) 2016-10-14 2018-04-19 Merial, Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
CA3044038A1 (en) 2016-11-16 2018-05-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
BR112020003217A2 (pt) 2017-08-14 2020-10-06 Boehringer Ingelheim Animal Health USA Inc. compostos pesticidas e parasiticidas de pirazolisoxazolina
EP3749096A1 (en) 2018-02-08 2020-12-16 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
AU2019301510B2 (en) 2018-07-09 2024-06-13 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anthelminthic heterocyclic compounds
CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
AU2020231319A1 (en) 2019-03-01 2021-10-21 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
KR20230028268A (ko) 2020-05-29 2023-02-28 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 헤테로시클릭 화합물
CN111748503B (zh) * 2020-08-04 2021-12-14 华中农业大学 一种深海独岛枝芽胞杆菌培养基和剂型
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
JP2025507585A (ja) 2022-02-17 2025-03-21 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー 流体製品メーラーを提供する方法及びシステム
WO2025257633A1 (en) 2024-06-12 2025-12-18 Boehringer Ingelheim Vetmedica Gmbh Long-acting castor oil-containing injectable formulations and methods of use thereof

Family Cites Families (10)

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US5075307A (en) * 1987-07-28 1991-12-24 Merck & Co., Inc. Paraherquamide and dihydroparaherquamide as antihelminthic agents
US4873247A (en) * 1987-11-27 1989-10-10 Goegelman Robert T Derivatives of paraherquamide isolated from a fermentation broth active as antiparasitic agents
US4978656A (en) * 1988-08-12 1990-12-18 Merck & Co., Inc. Synthetic derivatives of paraherquamide
US4866060A (en) * 1988-08-19 1989-09-12 Merck & Co., Inc. Use of the natural product marcfortines as antiparasitic agents
US4923867A (en) * 1988-08-24 1990-05-08 Merck & Co., Inc. Synthetic marcfortine derivatives useful as antiparasitic agents
NZ233043A (en) * 1989-03-30 1992-09-25 Merck & Co Inc Anthelmintic heterocyclic compounds prepared by action of cunninghamella blakesleeana on (dihydro)paraherquamide
IE904606A1 (en) * 1989-12-21 1991-07-03 Beecham Group Plc Novel products
GB9014194D0 (en) * 1990-06-26 1990-08-15 Pfizer Ltd Antiparasitic agents
WO1992022555A1 (en) * 1991-06-17 1992-12-23 Beecham Group Plc Paraherquamide derivatives, precursor thereof, processes for their preparation, microorganism used and their use as antiparasitic agents
TW410227B (en) * 1993-06-16 2000-11-01 Upjohn Co 14-substituted marcfortines and derivatives useful as antiparasitic agents

Also Published As

Publication number Publication date
NO980255D0 (no) 1998-01-20
HUP9802221A3 (en) 2000-05-29
AR038434A2 (es) 2005-01-12
CZ296008B6 (cs) 2005-12-14
HU226296B1 (hu) 2008-08-28
CN1277830C (zh) 2006-10-04
EP0871631B1 (en) 2005-11-30
FI118471B (fi) 2007-11-30
CN1495183A (zh) 2004-05-12
CA2225813A1 (en) 1997-02-06
TW334436B (en) 1998-06-21
ATE311390T1 (de) 2005-12-15
SK284833B6 (sk) 2005-12-01
HK1061242A1 (en) 2004-09-10
US5703078A (en) 1997-12-30
CA2225813C (en) 2008-02-26
EP0871631A1 (en) 1998-10-21
NO324287B1 (no) 2007-09-17
BR9612963B8 (pt) 2014-10-29
MY113806A (en) 2002-05-31
HUP9802221A2 (hu) 1999-02-01
NO980255L (no) 1998-03-20
RU2162090C2 (ru) 2001-01-20
MX9800625A (es) 1998-04-30
FI20050238L (fi) 2005-03-04
DK0871631T3 (da) 2006-03-13
CN1191537A (zh) 1998-08-26
BR9612972B8 (pt) 2014-10-29
HK1017883A1 (en) 1999-12-03
ZA965908B (en) 1997-01-12
KR100428335B1 (ko) 2004-06-16
PT1489082E (pt) 2013-12-23
FI115912B (fi) 2005-08-15
PL185007B1 (pl) 2003-01-31
US5750695A (en) 1998-05-12
WO1997003988A1 (en) 1997-02-06
AR038428A2 (es) 2005-01-12
CO4750664A1 (es) 1999-03-31
AR003466A1 (es) 1998-08-05
ES2439569T3 (es) 2014-01-23
EP1400523A3 (en) 2004-04-07
SI0871631T1 (sl) 2006-04-30
CZ11098A3 (cs) 1998-06-17
JP4122447B2 (ja) 2008-07-23
ES2249783T3 (es) 2006-04-01
AR038430A2 (es) 2005-01-12
SK5498A3 (en) 1998-08-05
PL324574A1 (en) 1998-06-08
EP1489082A1 (en) 2004-12-22
DE69635524T2 (de) 2006-07-06
BR9609812B8 (pt) 2014-10-29
AR038432A2 (es) 2005-01-12
AU6337396A (en) 1997-02-18
AU699644B2 (en) 1998-12-10
EP1400523A2 (en) 2004-03-24
SK285248B6 (sk) 2006-09-07
CN1125824C (zh) 2003-10-29
FI980112A0 (fi) 1998-01-20
JPH11509550A (ja) 1999-08-24
FI980112L (fi) 1998-01-20
BR9612973B8 (pt) 2014-10-29
ID30373A (id) 1997-01-23
AR038427A2 (es) 2005-01-12
AR038433A2 (es) 2005-01-12
AR038431A2 (es) 2005-01-12
EP1489082B1 (en) 2013-11-20
BR9609812A (pt) 1999-03-02
BR9612974B8 (pt) 2014-10-29
BR9612975B8 (pt) 2014-10-29
AR038429A2 (es) 2005-01-12
AR052907A1 (es) 2007-04-11
BR9612944B8 (pt) 2014-10-29
NZ311952A (en) 1999-03-29
JP2008007516A (ja) 2008-01-17
DE69635524D1 (de) 2006-01-05

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