DK1526870T3 - Kombination af loteprednol-etabonat OFHO til behandling af respiratoriske sygdomme, allergiske sygdomme, astma og COPD - Google Patents

Kombination af loteprednol-etabonat OFHO til behandling af respiratoriske sygdomme, allergiske sygdomme, astma og COPD

Info

Publication number: DK1526870T3
Authority: DK; Denmark
Prior art keywords: copd; asthma; treatment; loteprednol; allergic
Prior art date: 2002-08-09

Application number

DK03790851T

Other languages

Danish (da)

English (en)

Inventor

Mathias Locher

Robert Hermann

Original Assignee

Meda Pharma Gmbh & Co Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-09

Filing date

2003-08-04

Publication date

2007-09-10

2003-08-04 Application filed by Meda Pharma Gmbh & Co Kg filed Critical Meda Pharma Gmbh & Co Kg

2007-09-10 Application granted granted Critical

2007-09-10 Publication of DK1526870T3 publication Critical patent/DK1526870T3/da

Links

208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 title abstract 3
208000006673 asthma Diseases 0.000 title abstract 2
230000000172 allergic effect Effects 0.000 title 1
208000010668 atopic eczema Diseases 0.000 title 1
230000000241 respiratory effect Effects 0.000 title 1
229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 abstract 2
239000002587 phosphodiesterase IV inhibitor Substances 0.000 abstract 2
201000009961 allergic asthma Diseases 0.000 abstract 1
208000026935 allergic disease Diseases 0.000 abstract 1
239000003862 glucocorticoid Substances 0.000 abstract 1
YPZVAYHNBBHPTO-MXRBDKCISA-N loteprednol Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)OCCl)[C@@H]4[C@@H]3CCC2=C1 YPZVAYHNBBHPTO-MXRBDKCISA-N 0.000 abstract 1
229960001798 loteprednol Drugs 0.000 abstract 1
DPHDSIQHVGSITN-UHFFFAOYSA-N n-(3,5-dichloropyridin-4-yl)-2-[1-[(4-fluorophenyl)methyl]-5-hydroxyindol-3-yl]-2-oxoacetamide Chemical compound C1=C(C(=O)C(=O)NC=2C(=CN=CC=2Cl)Cl)C2=CC(O)=CC=C2N1CC1=CC=C(F)C=C1 DPHDSIQHVGSITN-UHFFFAOYSA-N 0.000 abstract 1
208000023504 respiratory system disease Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK03790851T 2002-08-09 2003-08-04 Kombination af loteprednol-etabonat OFHO til behandling af respiratoriske sygdomme, allergiske sygdomme, astma og COPD DK1526870T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10236688		2002-08-09
PCT/EP2003/008607 WO2004019984A1 (fr)	2002-08-09	2003-08-04	Nouvelle combinaison de glucocorticoides et d'inhibiteurs de pde-4 pour traiter des maladies des voies respiratoires, des maladies allergiques, de l'asthme et des maladies pulmonaires chroniques obstructives

Publications (1)

Publication Number	Publication Date
DK1526870T3 true DK1526870T3 (da)	2007-09-10

Family

ID=31968961

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03790851T DK1526870T3 (da)	2002-08-09	2003-08-04	Kombination af loteprednol-etabonat OFHO til behandling af respiratoriske sygdomme, allergiske sygdomme, astma og COPD

Country Status (18)

Country	Link
US (1)	US20050288265A1 (fr)
EP (1)	EP1526870B1 (fr)
JP (1)	JP2005539042A (fr)
CN (1)	CN1308038C (fr)
AT (1)	ATE361076T1 (fr)
AU (1)	AU2003255365B2 (fr)
CA (1)	CA2492645A1 (fr)
CY (1)	CY1107696T1 (fr)
DE (1)	DE50307184D1 (fr)
DK (1)	DK1526870T3 (fr)
EA (1)	EA008981B1 (fr)
ES (1)	ES2285238T3 (fr)
HR (1)	HRP20050224B1 (fr)
MX (1)	MXPA05001573A (fr)
NO (1)	NO20051212L (fr)
PT (1)	PT1526870E (fr)
UA (1)	UA82323C2 (fr)
WO (1)	WO2004019984A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10241407A1 (de) *	2002-09-06	2004-03-18	Elbion Ag	Behandlung nicht allergischer Rhinitis durch selektive Phosphodiesterase 4-Hemmstoffe
PL1713471T3 (pl)	2004-02-06	2012-06-29	Meda Pharma Gmbh & Co Kg	Kombinacja środków antycholinergicznych i inhibitorów fosfodiesterazy typu 4 do leczenia chorób oddechowych
AU2005210085B2 (en) *	2004-02-06	2010-06-24	Meda Pharma Gmbh & Co. Kg	The combination of anticholinergics and glucocorticoids for the long-term treatment of asthma and COPD
MX2007011273A (es)	2005-03-16	2007-11-08	Meda Pharma Gmbh & Co Kg	La combinacion de anticolinergicos y antagonistas del receptor de leucotrieno para el tratamiento de enfermedades respiratorias.
US8506934B2 (en)	2005-04-29	2013-08-13	Robert I. Henkin	Methods for detection of biological substances
WO2007071313A2 (fr)	2005-12-21	2007-06-28	Meda Pharma Gmbh & Co Kg	Combinaison d'anticholinergiques, de glucocorticoïdes, de bêta 2-agonistes, d'inhibiteur des pde4 et d'antileucotriène pour le traitement de maladies inflammatoires
CA2644889A1 (fr) *	2006-03-07	2007-09-13	Combinatorx, Incorporated	Compositions et procedes pour le traitement de troubles immunoinflammatoires
WO2008095136A2 (fr)	2007-01-31	2008-08-07	Henkin Robert I	Procédés de détection de substances biologiques
US8580801B2 (en)	2008-07-23	2013-11-12	Robert I. Henkin	Phosphodiesterase inhibitor treatment
CN102309756A (zh) *	2010-07-02	2012-01-11	天津金耀集团有限公司	含有磷酸二酯酶4抑制剂和糖皮质激素的治疗皮肤病的复方药物
HK1208162A1 (en)	2012-05-03	2016-02-26	Kala Pharmaceuticals, Inc.	Pharmaceutical nanoparticles showing improved mucosal transport
US9827191B2 (en)	2012-05-03	2017-11-28	The Johns Hopkins University	Compositions and methods for ophthalmic and/or other applications
US11596599B2 (en)	2012-05-03	2023-03-07	The Johns Hopkins University	Compositions and methods for ophthalmic and/or other applications
WO2013166408A1 (fr) *	2012-05-03	2013-11-07	Kala Pharmaceuticals, Inc.	Nanoparticules pharmaceutiques présentant un transport muqueux amélioré
US10864219B2 (en)	2012-05-03	2020-12-15	The Johns Hopkins University	Compositions and methods for ophthalmic and/or other applications
ES2744542T3 (es) *	2013-03-15	2020-02-25	Robert I Henkin	Inhibidores de fosfodiesterasa para tratar trastornos gustativos y olfativos
US10598672B2 (en)	2014-02-18	2020-03-24	Cyrano Therapeutics, Inc.	Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
WO2021194893A1 (fr)	2020-03-24	2021-09-30	Cyrano Therapeutics, Inc.	Traitement d'un dysfonctionnement chimiosensoriel résultant d'une infection à coronavirus

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4996335A (en) *	1980-07-10	1991-02-26	Nicholas S. Bodor	Soft steroids having anti-inflammatory activity
SE449106B (sv) *	1980-07-10	1987-04-06	Otsuka Pharma Co Ltd	Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
DK1014943T3 (da) *	1997-02-05	2002-10-14	Jago Res Ag	Medicinske aerosolformuleringer
DE19917504A1 (de) *	1999-04-17	2000-10-19	Dresden Arzneimittel	Verwendung von Hydroxyindolen, die Inhibitoren der Phosphodiesterase 4 sind, zur Therapie chronisch obstruktiver Lungenerkrankungen
DE59913617D1 (de) *	1998-04-28	2006-08-03	Elbion Ag	Indolderivate und deren Verwendung als Inhibitoren der Phosphodiesterase 4.
DE19947234A1 (de) *	1999-09-30	2001-04-05	Asta Medica Ag	Neue Kombination von Loteprednol und Antihistaminika
US20040214805A1 (en) *	1999-11-02	2004-10-28	Smithkline Beecham Corporation	Method and compositions for treating pulmonary diseases
AR029189A1 (es) *	1999-11-02	2003-06-18	Smithkline Beecham Corp	Uso de un inhibidor de fosfodiesterasa 4 y un corticoesteroide antiinflamatorio en forma combinada, separadamente o separadamente secuencial para la preparacion de un medicamento
ES2222370T3 (es) *	2000-05-19	2005-02-01	Alcon Inc.	Derivados de disulfuro de anilina para tratar enfermedades alergicas.
GB0123951D0 (en) *	2001-10-05	2001-11-28	Glaxo Group Ltd	Therapies for treating respiratory diseases
KR100898894B1 (ko) *	2001-11-05	2009-05-21	메르크 파텐트 게엠베하	히드라조노-말로니트릴
US20030092706A1 (en) *	2001-11-09	2003-05-15	Johannes Barsig	Combination

2003
- 2003-04-08 UA UAA200500512A patent/UA82323C2/uk unknown
- 2003-08-04 PT PT03790851T patent/PT1526870E/pt unknown
- 2003-08-04 ES ES03790851T patent/ES2285238T3/es not_active Expired - Lifetime
- 2003-08-04 MX MXPA05001573A patent/MXPA05001573A/es active IP Right Grant
- 2003-08-04 DK DK03790851T patent/DK1526870T3/da active
- 2003-08-04 US US10/523,802 patent/US20050288265A1/en not_active Abandoned
- 2003-08-04 AT AT03790851T patent/ATE361076T1/de not_active IP Right Cessation
- 2003-08-04 WO PCT/EP2003/008607 patent/WO2004019984A1/fr not_active Ceased
- 2003-08-04 DE DE50307184T patent/DE50307184D1/de not_active Expired - Lifetime
- 2003-08-04 EA EA200500328A patent/EA008981B1/ru not_active IP Right Cessation
- 2003-08-04 JP JP2004531853A patent/JP2005539042A/ja active Pending
- 2003-08-04 CA CA002492645A patent/CA2492645A1/fr not_active Abandoned
- 2003-08-04 AU AU2003255365A patent/AU2003255365B2/en not_active Ceased
- 2003-08-04 HR HR20050224A patent/HRP20050224B1/xx not_active IP Right Cessation
- 2003-08-04 EP EP03790851A patent/EP1526870B1/fr not_active Expired - Lifetime
- 2003-08-04 CN CNB038190575A patent/CN1308038C/zh not_active Expired - Fee Related
2005
- 2005-03-08 NO NO20051212A patent/NO20051212L/no not_active Application Discontinuation
2007
- 2007-07-12 CY CY20071100927T patent/CY1107696T1/el unknown

Also Published As

Publication number	Publication date
CN1308038C (zh)	2007-04-04
WO2004019984A1 (fr)	2004-03-11
CN1674939A (zh)	2005-09-28
AU2003255365B2 (en)	2009-02-19
ATE361076T1 (de)	2007-05-15
CA2492645A1 (fr)	2004-03-11
PT1526870E (pt)	2007-07-09
UA82323C2 (uk)	2008-04-10
AU2003255365A1 (en)	2004-03-19
HRP20050224A2 (en)	2005-04-30
US20050288265A1 (en)	2005-12-29
NO20051212D0 (no)	2005-03-08
EA008981B1 (ru)	2007-10-26
NO20051212L (no)	2005-03-08
HRP20050224B1 (hr)	2007-12-31
ES2285238T3 (es)	2007-11-16
JP2005539042A (ja)	2005-12-22
DE50307184D1 (de)	2007-06-14
CY1107696T1 (el)	2013-04-18
HK1078463A1 (en)	2006-03-17
EP1526870B1 (fr)	2007-05-02
EP1526870A1 (fr)	2005-05-04
EA200500328A1 (ru)	2005-06-30
MXPA05001573A (es)	2005-04-25

Publication	Publication Date	Title
CY1107696T1 (el)	2013-04-18	Συνδιασμος εταβονικης λοτεπρεδνολης και dfho για την αντιμετωπιση αναπνευστικων παθησεων, αλλεργικων παθησεων, ασθματος και copd
MXPA02011311A (es)	2003-04-25	Composicion novedosa.
SE0200356D0 (sv)	2002-02-05	Novel use
ATE508735T1 (de)	2011-05-15	Pulmonale verabreichung von aminoglykosiden
NO20052591L (no)	2005-07-29	Pyridopyrolizin og pyridoindolizinderivater
DK1718336T3 (da)	2008-10-20	Ny kombination af anticholinergikum og beta-mimetika til behandling af luftvejssygdomme
WO2005041864A3 (fr)	2006-05-18	Technique de traitement de prevention d'inflammation respiratoire avec un inhibiteur de cyclooxygenase-2 combine a un inhibiteur de phosphodiesterase 4 et compositions a partir de ceux-ci
DK1478438T3 (da)	2012-08-27	Fremgangsmåder og sammensætninger til behandling af astma
WO2005086915A3 (fr)	2006-03-23	Traitement de la bronchopneumopathie chronique obstructive par inhalation a faible dose d'inhibiteur de protease
SE9900834D0 (sv)	1999-03-09	Novel combination
IS2575B (is)	2010-02-15	Ný samverkandi samsetning sem felur í sér róflúmílast og formóteról
BG106748A (en)	2003-02-28	Method and compositions for treating pulmonary diseases
MXPA04007294A (es)	2004-10-29	Composicion para inhalacion.
IS7899A (is)	2005-06-20	Samverkandi samsetning sem felur í sér róflúmílast og (R.R)-formóteról
NO20045344L (no)	2004-12-06	Kombinasjon for behandling av luftveisforstyrrelser
GB0218573D0 (en)	2002-09-18	Treatment of chronic obstructive pulmonary disease (COPD) and other disorders