DK1544201T3 - Nye cycloalkanedionderivater, fremgangsmåde til fremstilling deraf og deres farmakologiske anvendelser - Google Patents
Nye cycloalkanedionderivater, fremgangsmåde til fremstilling deraf og deres farmakologiske anvendelserInfo
- Publication number
- DK1544201T3 DK1544201T3 DK03784210T DK03784210T DK1544201T3 DK 1544201 T3 DK1544201 T3 DK 1544201T3 DK 03784210 T DK03784210 T DK 03784210T DK 03784210 T DK03784210 T DK 03784210T DK 1544201 T3 DK1544201 T3 DK 1544201T3
- Authority
- DK
- Denmark
- Prior art keywords
- novel
- processes
- preparation
- cycloalkanedione
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200201811A ES2199086B1 (es) | 2002-07-31 | 2002-07-31 | Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1544201T3 true DK1544201T3 (da) | 2006-10-30 |
Family
ID=31198114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03784210T DK1544201T3 (da) | 2002-07-31 | 2003-07-29 | Nye cycloalkanedionderivater, fremgangsmåde til fremstilling deraf og deres farmakologiske anvendelser |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7351732B2 (de) |
| EP (1) | EP1544201B1 (de) |
| JP (1) | JP2005539017A (de) |
| KR (1) | KR20050042471A (de) |
| CN (2) | CN100422185C (de) |
| AT (1) | ATE331717T1 (de) |
| AU (1) | AU2003254512A1 (de) |
| BR (1) | BR0313375A (de) |
| CA (1) | CA2492837A1 (de) |
| CY (1) | CY1106170T1 (de) |
| DE (1) | DE60306534T2 (de) |
| DK (1) | DK1544201T3 (de) |
| ES (2) | ES2199086B1 (de) |
| IL (1) | IL166469A0 (de) |
| MX (1) | MXPA05001245A (de) |
| NO (1) | NO20051068L (de) |
| NZ (1) | NZ538489A (de) |
| PL (1) | PL373644A1 (de) |
| PT (1) | PT1544201E (de) |
| RU (1) | RU2322445C2 (de) |
| UA (1) | UA79801C2 (de) |
| WO (1) | WO2004014915A1 (de) |
| ZA (1) | ZA200500784B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2199086B1 (es) | 2002-07-31 | 2005-06-01 | Cepa Schwarz Pharma Sl | Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas. |
| ES2238015B1 (es) * | 2004-01-30 | 2006-11-01 | Cepa Schwarz Pharma, S.L. | Derivados de cicloalcanodionas con actividad neuroprotectora. |
| WO2008015538A2 (en) * | 2006-07-31 | 2008-02-07 | Schwarz Pharma S.L. | Use of diaza- and thiaza-cycloalkanediones for preventing and/or treating pain and /or migraine |
| EP2338873A1 (de) | 2009-12-22 | 2011-06-29 | Gmeiner, Peter | Neue Aminotetralinderivate |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4055410A (en) * | 1976-03-15 | 1977-10-25 | E. I. Du Pont De Nemours And Company | Substituted bromo- or chloroacetamide herbicides |
| EP0002978B1 (de) * | 1977-12-29 | 1982-10-06 | Synthelabo | Thiazolidindion-2,4 Derivate, deren Herstellung und Verwendung als Arzneimittel |
| DE3901814A1 (de) * | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
| EP0510691B1 (de) * | 1991-04-26 | 2004-11-03 | Osaka Bioscience Institute | Für ein menschliches Zelloberflächen-Antigen kodierende DNS |
| TW288010B (de) * | 1992-03-05 | 1996-10-11 | Pfizer | |
| AP486A (en) * | 1993-04-27 | 1996-04-16 | Pfizer | Indole derivatives. |
| AU3079295A (en) | 1994-09-01 | 1996-03-22 | Universidad Complutense De Madrid | New arylpiperazine derivatives |
| ES2082727B1 (es) | 1994-09-01 | 1996-10-16 | Univ Madrid Complutense | Nuevos derivados de arilpiperazinas. |
| ES2094690B1 (es) | 1994-11-22 | 1997-08-01 | Univ Madrid Complutense | Nuevos derivados de imida-piperazinas. |
| ES2109190B1 (es) | 1996-03-22 | 1998-07-01 | Univ Madrid Complutense | Nuevos derivados de bencimidazol con afinidad por los receptores serotoninergicos 5-ht /5-ht |
| ES2129370B1 (es) | 1997-09-23 | 2000-03-01 | Univ Madrid Complutense | Procedimiento para la obtencion del 2-(4-(4-(m-etilsulfonamidofenil)p iperazin-1-il(butil)-1,3-dioxoperhidropirrolo)1,2-c(imidazol |
| US6133277A (en) | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
| ES2154605B1 (es) | 1999-09-14 | 2001-11-16 | Univ Madrid Complutense | Nuevos derivados mixtos de bencimidazol-arilpiperazina con afinidad por los receptores serotoninergicos 5-ht1a y 5-ht3 |
| DE10148425A1 (de) | 2001-10-01 | 2003-04-17 | Bayer Ag | Chromane |
| ES2199086B1 (es) | 2002-07-31 | 2005-06-01 | Cepa Schwarz Pharma Sl | Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas. |
| ES2238015B1 (es) | 2004-01-30 | 2006-11-01 | Cepa Schwarz Pharma, S.L. | Derivados de cicloalcanodionas con actividad neuroprotectora. |
| EP1674103A1 (de) | 2004-12-27 | 2006-06-28 | Cepa Schwarz Pharma s.l. | Arylpiperazine Derivative als 5-HT1A Rezeptor Liganden |
-
2002
- 2002-07-31 ES ES200201811A patent/ES2199086B1/es not_active Expired - Fee Related
-
2003
- 2003-07-29 BR BR0313375-3A patent/BR0313375A/pt not_active IP Right Cessation
- 2003-07-29 WO PCT/ES2003/000394 patent/WO2004014915A1/es not_active Ceased
- 2003-07-29 DE DE60306534T patent/DE60306534T2/de not_active Expired - Fee Related
- 2003-07-29 NZ NZ538489A patent/NZ538489A/en unknown
- 2003-07-29 US US10/522,697 patent/US7351732B2/en not_active Expired - Fee Related
- 2003-07-29 EP EP03784210A patent/EP1544201B1/de not_active Expired - Lifetime
- 2003-07-29 RU RU2005102821/04A patent/RU2322445C2/ru not_active IP Right Cessation
- 2003-07-29 CN CNB038183390A patent/CN100422185C/zh not_active Expired - Fee Related
- 2003-07-29 JP JP2004526925A patent/JP2005539017A/ja active Pending
- 2003-07-29 MX MXPA05001245A patent/MXPA05001245A/es active IP Right Grant
- 2003-07-29 AU AU2003254512A patent/AU2003254512A1/en not_active Abandoned
- 2003-07-29 CN CNA2007101694908A patent/CN101172977A/zh active Pending
- 2003-07-29 PL PL03373644A patent/PL373644A1/xx not_active Application Discontinuation
- 2003-07-29 DK DK03784210T patent/DK1544201T3/da active
- 2003-07-29 ES ES03784210T patent/ES2271673T3/es not_active Expired - Lifetime
- 2003-07-29 PT PT03784210T patent/PT1544201E/pt unknown
- 2003-07-29 UA UAA200500843A patent/UA79801C2/uk unknown
- 2003-07-29 KR KR1020057001543A patent/KR20050042471A/ko not_active Ceased
- 2003-07-29 CA CA002492837A patent/CA2492837A1/en not_active Abandoned
- 2003-07-29 AT AT03784210T patent/ATE331717T1/de not_active IP Right Cessation
-
2005
- 2005-01-24 IL IL16646905A patent/IL166469A0/xx unknown
- 2005-01-25 ZA ZA200500784A patent/ZA200500784B/xx unknown
- 2005-02-25 NO NO20051068A patent/NO20051068L/no not_active Application Discontinuation
-
2006
- 2006-09-26 CY CY20061101376T patent/CY1106170T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ538489A (en) | 2006-09-29 |
| CN101172977A (zh) | 2008-05-07 |
| CA2492837A1 (en) | 2004-02-19 |
| PT1544201E (pt) | 2006-11-30 |
| WO2004014915A1 (es) | 2004-02-19 |
| ES2199086A1 (es) | 2004-02-01 |
| CN100422185C (zh) | 2008-10-01 |
| UA79801C2 (en) | 2007-07-25 |
| ES2271673T3 (es) | 2007-04-16 |
| IL166469A0 (en) | 2006-01-15 |
| AU2003254512A1 (en) | 2004-02-25 |
| US20050250777A1 (en) | 2005-11-10 |
| EP1544201B1 (de) | 2006-06-28 |
| US7351732B2 (en) | 2008-04-01 |
| ES2199086B1 (es) | 2005-06-01 |
| CY1106170T1 (el) | 2011-06-08 |
| KR20050042471A (ko) | 2005-05-09 |
| JP2005539017A (ja) | 2005-12-22 |
| ZA200500784B (en) | 2006-08-30 |
| RU2005102821A (ru) | 2005-10-10 |
| RU2322445C2 (ru) | 2008-04-20 |
| ATE331717T1 (de) | 2006-07-15 |
| PL373644A1 (en) | 2005-09-05 |
| NO20051068L (no) | 2005-02-25 |
| DE60306534T2 (de) | 2007-04-19 |
| CN1671708A (zh) | 2005-09-21 |
| EP1544201A1 (de) | 2005-06-22 |
| BR0313375A (pt) | 2005-06-21 |
| MXPA05001245A (es) | 2005-09-12 |
| DE60306534D1 (de) | 2006-08-10 |
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