DK198488D0 - Fremgangsmaade til fremstilling af stabile sucralfat suspensioner og laegemidler omfattende saadanne - Google Patents

Fremgangsmaade til fremstilling af stabile sucralfat suspensioner og laegemidler omfattende saadanne

Info

Publication number: DK198488D0
Authority: DK; Denmark
Prior art keywords: stable; sucralfate; suspensions; sucralphate; procedure
Prior art date: 1987-04-15

Application number

DK198488A

Other languages

English (en)

Other versions

DK175683B1 (da

DK198488A (da

Inventor

Giorgio Zagnoli

Ubaldo Conte

Paolo Colombo

Carla Caramella

Original Assignee

Lisapharma Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-04-15

Filing date

1988-04-12

Publication date

1988-04-12

1988-04-12 Application filed by Lisapharma Spa filed Critical Lisapharma Spa

1988-04-12 Publication of DK198488D0 publication Critical patent/DK198488D0/da

1988-10-17 Publication of DK198488A publication Critical patent/DK198488A/da

2005-01-17 Application granted granted Critical

2005-01-17 Publication of DK175683B1 publication Critical patent/DK175683B1/da

Links

239000000725 suspension Substances 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
MNQYNQBOVCBZIQ-JQOFMKNESA-A sucralfate Chemical compound O[Al](O)OS(=O)(=O)O[C@@H]1[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](COS(=O)(=O)O[Al](O)O)O[C@H]1O[C@@]1(COS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)O1 MNQYNQBOVCBZIQ-JQOFMKNESA-A 0.000 abstract 4
229960004291 sucralfate Drugs 0.000 abstract 4
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
150000001720 carbohydrates Chemical class 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000001376 precipitating effect Effects 0.000 abstract 1
239000000375 suspending agent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Dispersion Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Stereo-Broadcasting Methods (AREA)
Signal Processing For Digital Recording And Reproducing (AREA)
Lift-Guide Devices, And Elevator Ropes And Cables (AREA)

DK198801984A 1987-04-15 1988-04-12 Fremgangsmåde til fremstilling af stabile sucralfatsuspensioner DK175683B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT20129/87A IT1203901B (it)	1987-04-15	1987-04-15	Composizioni farmaceutiche sotto forma di sospensioni stabili di sucralfato esenti da agenti sospendenti
IT2012987		1987-04-15

Publications (3)

Publication Number	Publication Date
DK198488D0 true DK198488D0 (da)	1988-04-12
DK198488A DK198488A (da)	1988-10-17
DK175683B1 DK175683B1 (da)	2005-01-17

Family

ID=11164041

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198801984A DK175683B1 (da)	1987-04-15	1988-04-12	Fremgangsmåde til fremstilling af stabile sucralfatsuspensioner

Country Status (20)

Country	Link
US (1)	US5321013A (da)
EP (1)	EP0286978B1 (da)
JP (1)	JPS6445312A (da)
KR (1)	KR930006037B1 (da)
CN (1)	CN1021629C (da)
AT (1)	ATE58144T1 (da)
AU (1)	AU623853B2 (da)
CA (1)	CA1306945C (da)
DE (1)	DE3860967D1 (da)
DK (1)	DK175683B1 (da)
ES (1)	ES2021781B3 (da)
FI (1)	FI88257C (da)
GR (1)	GR3002515T3 (da)
IE (1)	IE61339B1 (da)
IN (1)	IN169494B (da)
IT (1)	IT1203901B (da)
MX (1)	MX11135A (da)
NO (1)	NO174656C (da)
NZ (1)	NZ224253A (da)
ZA (1)	ZA882476B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2735559B2 (ja) *	1988-03-02	1998-04-02	中外製薬株式会社	懸濁液
IT1230157B (it) *	1989-06-16	1991-10-14	Lisapharma Spa	Uso di sucralfato gel umido per il trattamento di ulcere del derma e come veicolo di farmaci ad attivita' topica
FR2657010B1 (fr) *	1990-01-12	1992-05-15	Pf Medicament	Composition pharmaceutique sous forme de suspension aqueuse stable a base de sucrafalte et d'une substance anti-acide ainsi que son procede de preparation.
CA2090479C (en) *	1990-08-31	2002-01-15	Kiyoshige Ochi	Stock solution of sucralfate suspended in water and production thereof
DK86492D0 (da) *	1992-06-30	1992-06-30	Bukh Meditec	Laegemiddel
IT1264546B1 (it) *	1993-07-30	1996-10-02	Lisapharma Spa	Composizione farmaceutica ad attivita' antiacida in forma di sospensione a base di gel di sucralfato
ATE213635T1 (de) *	1994-04-26	2002-03-15	Chugai Pharmaceutical Co Ltd	Verfahren für die herstellung schmelz-granulierte sucralfatzubereitung
IT1274735B (it) *	1994-08-25	1997-07-24	Enosys S P A	Farmaco e vettore per le patologie infiammatorie ed erosive del tratto gastrointestinale a base di sucralfato allo stato di gel secco
IT1284030B1 (it) *	1996-06-18	1998-05-08	Solchem Italiana Spa	Metodo per la produzione di sospensioni acquose stabili, utili nelle composizioni farmaceutiche
IT1301969B1 (it) *	1998-07-30	2000-07-20	Lisapharma Spa	Sucralfato gel secco granulare e poroso procedimento per la suapreparazione, e composizioni farmaceutiche solide che lo contengono
US6391860B1 (en) *	1999-09-09	2002-05-21	Mcgrath Patrick D.	Method for preparation and use of paste formed by controlled reaction of sucralfate with hydrochloric acid
CN100425244C (zh) *	2004-04-14	2008-10-15	中国人民解放军总医院	注射用硫酸铝，用于治疗膀胱肿瘤的注射用硫酸铝注射液
CA2736884A1 (en) *	2008-09-17	2010-03-25	Patrick D. Mcgrath	Antimicrobial sucralfate paste methods and compositions
WO2014151565A1 (en)	2013-03-15	2014-09-25	The Brigham And Women's Hospital, Inc.	Compounds to modulate intestinal absorption of nutrients
GR1008308B (el)	2013-05-31	2014-10-02	UNI-PHARMA ΚΛΕΩΝ ΤΣΕΤΗΣ ΦΑΡΜΑΚΕΥΤΙΚΑ ΕΡΓΑΣΤΗΡΙΑ ΑΒΕΕ με δ.τ. "UNI-PHARMA ABEE",	Τοπικες φαρμακευτικες και ιατροτεχνολογικες συνθεσεις που περιεχουν συνδυασμους σουκραλφατης, υαλουρονικου οξεος, αργινινης και ενος φυσικου ενυδατικου παραγοντα
JP6627485B2 (ja) *	2015-01-28	2020-01-08	ライオン株式会社	ゲル組成物及びその製造方法
JP6515680B2 (ja) *	2015-05-27	2019-05-22	ライオン株式会社	スクラルファート含有液状組成物
US10973846B2 (en)	2015-09-24	2021-04-13	The Brigham And Women's Hospital, Inc.	Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients
FR3043556B1 (fr) *	2015-11-17	2020-01-10	Urgo Recherche Innovation Et Developpement	Utilisation de composes oligosaccharidiques pour activer l'angiogenese
CN109431972B (zh) *	2018-11-20	2022-02-22	昆明积大制药股份有限公司	一种粒径为100nm—500nm的硫糖铝凝胶的成胶方法
CN114269386A (zh)	2019-06-10	2022-04-01	布里格姆及妇女医院股份有限公司	水活化的粘膜粘附性组合物和递送生物活性物质的方法
IT202100000059A1 (it) *	2021-01-04	2022-07-04	Nyuma Pharma Srl	Nuove composizioni di sucralfato in alginato e loro utilizzo in terapia
CN118304859A (zh) *	2024-03-25	2024-07-09	康诺瑞达(福建)新药开发有限公司	一种硫糖铝混悬凝胶的制备方法以及检测其与蛋白亲和力的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2512344A1 (fr) *	1981-09-08	1983-03-11	Af Aplicaciones Far Lab	Procede de fabrication d'une suspension stable d'hydroxyde d'alumine et/ou d'hydroxyde de magnesie comme agent actif des antacida
JPS5978116A (ja) *	1982-10-27	1984-05-04	Chugai Pharmaceut Co Ltd	スクラルフェ−ト製剤
DE3429263A1 (de) *	1984-08-08	1986-02-20	Gödecke AG, 1000 Berlin	Verfahren zur stabilisierung filtrierbarer antacida mit hexitolen
DE3430809A1 (de) *	1984-08-22	1986-03-06	Merck Patent Gmbh, 6100 Darmstadt	Sucralfat-suspension

1987
- 1987-04-15 IT IT20129/87A patent/IT1203901B/it active
1988
- 1988-04-07 IN IN288/CAL/88A patent/IN169494B/en unknown
- 1988-04-07 ES ES88105534T patent/ES2021781B3/es not_active Expired - Lifetime
- 1988-04-07 DE DE8888105534T patent/DE3860967D1/de not_active Expired - Fee Related
- 1988-04-07 EP EP88105534A patent/EP0286978B1/en not_active Expired - Lifetime
- 1988-04-07 IE IE103888A patent/IE61339B1/en not_active IP Right Cessation
- 1988-04-07 AT AT88105534T patent/ATE58144T1/de not_active IP Right Cessation
- 1988-04-08 ZA ZA882476A patent/ZA882476B/xx unknown
- 1988-04-12 DK DK198801984A patent/DK175683B1/da not_active IP Right Cessation
- 1988-04-14 KR KR1019880004243A patent/KR930006037B1/ko not_active Expired - Lifetime
- 1988-04-14 CN CN88102143A patent/CN1021629C/zh not_active Expired - Fee Related
- 1988-04-14 NZ NZ224253A patent/NZ224253A/xx unknown
- 1988-04-14 NO NO881625A patent/NO174656C/no not_active IP Right Cessation
- 1988-04-14 AU AU14643/88A patent/AU623853B2/en not_active Ceased
- 1988-04-14 CA CA000564177A patent/CA1306945C/en not_active Expired - Lifetime
- 1988-04-15 JP JP63091854A patent/JPS6445312A/ja active Granted
- 1988-04-15 FI FI881769A patent/FI88257C/fi active IP Right Grant
- 1988-04-15 MX MX1113588A patent/MX11135A/es unknown
1990
- 1990-01-08 US US07/462,950 patent/US5321013A/en not_active Expired - Lifetime
- 1990-11-08 GR GR90400888T patent/GR3002515T3/el unknown

Also Published As

Publication number	Publication date
KR930006037B1 (ko)	1993-07-03
FI88257B (fi)	1993-01-15
AU1464388A (en)	1988-10-20
FI881769A0 (fi)	1988-04-15
NZ224253A (en)	1991-03-26
IN169494B (da)	1991-10-26
JPS6445312A (en)	1989-02-17
DK175683B1 (da)	2005-01-17
MX11135A (es)	1993-12-01
AU623853B2 (en)	1992-05-28
EP0286978A1 (en)	1988-10-19
NO174656B (no)	1994-03-07
CN88102143A (zh)	1988-12-28
DE3860967D1 (de)	1990-12-13
IT1203901B (it)	1989-02-23
GR3002515T3 (en)	1993-01-25
NO881625L (no)	1988-10-17
ATE58144T1 (de)	1990-11-15
ES2021781B3 (es)	1991-11-16
EP0286978B1 (en)	1990-11-07
FI88257C (fi)	1993-04-26
CA1306945C (en)	1992-09-01
DK198488A (da)	1988-10-17
IE61339B1 (en)	1994-11-02
US5321013A (en)	1994-06-14
CN1021629C (zh)	1993-07-21
KR880012211A (ko)	1988-11-26
NO174656C (no)	1994-06-15
JPH0576927B2 (da)	1993-10-25
IE881038L (en)	1988-10-15
ZA882476B (en)	1988-09-29
IT8720129A0 (it)	1987-04-15
NO881625D0 (no)	1988-04-14
FI881769L (fi)	1988-10-16

Legal Events

Date	Code	Title	Description
2007-12-10	PBP	Patent lapsed	Country of ref document: DK

Publication	Publication Date	Title
DK198488A (da)	1988-10-17	Fremgangsmaade til fremstilling af stabile sucralfat suspensioner og laegemidler omfattende saadanne
ATE59287T1 (de)	1991-01-15	Verfahren zur herstellung einer auf der stelle zubereitbaren homogenen mikrokapselsuspension.
DK280789A (da)	1989-12-12	Komplekser af beta-cyclodextrin med salte af ibuprofen, fremgangsmaade til fremstilling af saadanne komplekser og farmaceutiske midler indeholdende disse
NL300027I2 (nl)	2001-07-02	Omeprazole-derivaten.
FI913536A0 (fi)	1991-07-23	Aggregat eller cluster bestaoende av i vatten svaellbara polymerer med oekad hydratiseringshastighet aen icke associerade i vatten svaellbara polymerer.
NO900613L (no)	1990-08-10	Fremgangsmaate for fremstilling av aktiverte chitosaner oganvendelse ved fremstilling av chitosanderivater.
GR880100532A (el)	1989-05-25	Υδατικα αιωρηματα θιξοτροπικου αργιλου περιεχοντα σταθεροποιητεσαλατων λιπαρου οξεος αλκαλικου μεταλλου.
HUT59832A (en)	1992-07-28	Process for producing pharmaceutical compositions containing calcitonin
ATE103492T1 (de)	1994-04-15	Waessrige sucralfate-suspension.
BR0011141A (pt)	2002-02-26	Composição de éter de celulose para cápsulas isentas de tubidez e processo para sua preparação
KR880013557A (ko)	1988-12-21	신규 안과용 조성물
DK0436252T3 (da)	1993-12-27	Farmaceutisk præparat til oral administration i flydende form
FR2631344B1 (fr)	1993-12-31	Procede de preparation de poudre fine d'acide hyaluronique ou d'hyaluronate de sodium et poudre fine ainsi obtenue
KR880008808A (ko)	1988-09-13	비경구투여용 현탁액
AU618896B2 (en)	1992-01-09	Stable solutions of rebeccamycin analog and preparation thereof
ES482138A1 (es)	1980-04-01	Procedimiento para la obtencion de 1-bencil -fenil-piperidi-nas.
HUP0003093A2 (hu)	2001-08-28	Nevirapin hemihidrátot tartalmazó gyógyszerészeti szuszpenziók
FR2657010B1 (fr)	1992-05-15	Composition pharmaceutique sous forme de suspension aqueuse stable a base de sucrafalte et d'une substance anti-acide ainsi que son procede de preparation.
KR950005832A (ko)	1995-03-20	5'-구아닐산 2나트륨 7수화물 결정의 대형화 방법
YU48230B (sh)	1997-08-22	Kristalni deoksispergvalin i postupak za njegovo pripremanje
GB1025920A (en)	1966-04-14	Method of producing chlorpromazine salt