DK159849C - Substituerede 5-chlor-anthra(1,9-cd)pyrazol-6(2h)-oner - Google Patents

Substituerede 5-chlor-anthra(1,9-cd)pyrazol-6(2h)-oner

Info

Publication number
DK159849C
DK159849C DK430389A DK430389A DK159849C DK 159849 C DK159849 C DK 159849C DK 430389 A DK430389 A DK 430389A DK 430389 A DK430389 A DK 430389A DK 159849 C DK159849 C DK 159849C
Authority
DK
Denmark
Prior art keywords
oner
anthra
chlor
pyrazol
substituted
Prior art date
Application number
DK430389A
Other languages
English (en)
Other versions
DK430389A (da
DK159849B (da
DK430389D0 (da
Inventor
Howard Daniel Hollis Showalter
Judith L Johnson
Leslie M Webel
Edward F Elslager
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/507,961 external-priority patent/US4556654A/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK430389A publication Critical patent/DK430389A/da
Publication of DK430389D0 publication Critical patent/DK430389D0/da
Publication of DK159849B publication Critical patent/DK159849B/da
Application granted granted Critical
Publication of DK159849C publication Critical patent/DK159849C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B5/00Dyes with an anthracene nucleus condensed with one or more heterocyclic rings with or without carbocyclic rings
    • C09B5/02Dyes with an anthracene nucleus condensed with one or more heterocyclic rings with or without carbocyclic rings the heterocyclic ring being only condensed in peri position
    • C09B5/16Benz-diazabenzanthrones, e.g. anthrapyrimidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205Radicals derived from carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK430389A 1982-07-23 1989-08-31 Substituerede 5-chlor-anthra(1,9-cd)pyrazol-6(2h)-oner DK159849C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US40115782A 1982-07-23 1982-07-23
US40115782 1982-07-23
US06/507,961 US4556654A (en) 1983-06-28 1983-06-28 Antimicrobial substituted anthra[1,9-cd]pyrazol-6(2H)-ones
US50796183 1983-06-28

Publications (4)

Publication Number Publication Date
DK430389A DK430389A (da) 1989-08-31
DK430389D0 DK430389D0 (da) 1989-08-31
DK159849B DK159849B (da) 1990-12-17
DK159849C true DK159849C (da) 1991-05-13

Family

ID=27017319

Family Applications (3)

Application Number Title Priority Date Filing Date
DK329683A DK159429C (da) 1982-07-23 1983-07-18 Analogifremgangsmaade til fremstilling af substituerede anthra(1,9-cd)pyrazol-6(2h)-oner
DK430289A DK160251C (da) 1982-07-23 1989-08-31 Analogifremgangsmaade til fremstilling af substituerede anthra(1,9-cd)pyrazol-6(2h)-oner
DK430389A DK159849C (da) 1982-07-23 1989-08-31 Substituerede 5-chlor-anthra(1,9-cd)pyrazol-6(2h)-oner

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK329683A DK159429C (da) 1982-07-23 1983-07-18 Analogifremgangsmaade til fremstilling af substituerede anthra(1,9-cd)pyrazol-6(2h)-oner
DK430289A DK160251C (da) 1982-07-23 1989-08-31 Analogifremgangsmaade til fremstilling af substituerede anthra(1,9-cd)pyrazol-6(2h)-oner

Country Status (18)

Country Link
EP (1) EP0103381B1 (da)
JP (2) JPH072719B2 (da)
KR (1) KR900005026B1 (da)
AR (1) AR240315A1 (da)
AU (1) AU549659B2 (da)
CA (1) CA1230115A (da)
DE (1) DE3373811D1 (da)
DK (3) DK159429C (da)
ES (3) ES8504731A1 (da)
FI (1) FI82932C (da)
GR (1) GR79610B (da)
HU (1) HU195779B (da)
IE (1) IE56782B1 (da)
IL (1) IL69211A (da)
NO (1) NO160000C (da)
NZ (1) NZ205001A (da)
PH (1) PH20906A (da)
PT (1) PT77088B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1251451A (en) * 1984-06-29 1989-03-21 Ellen M. Berman Benzoseleno¬4,3,2-cd|indazole compositions and methods for their production and use
CA1251450A (en) * 1984-06-29 1989-03-21 David B. Capps Benzopyrano¬4,3,2-cd|indazole compositions and methods for their production and use
US4608439A (en) * 1985-04-26 1986-08-26 Warner-Lambert Company Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones
US4672129A (en) * 1986-05-05 1987-06-09 Warner-Lambert Company Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones
GB9107843D0 (en) * 1991-04-12 1991-05-29 Patterson Laurence H Anti-cancer compounds
GB9107852D0 (en) * 1991-04-12 1991-05-29 Patterson Laurence H Anti-cancer compounds
RU2130937C1 (ru) * 1992-09-08 1999-05-27 Дзе Юниверсити оф Вермонт 2-аминоалкил-5-аминоалкиламинозамещенные изохиноиндазол-6-(2н)-оны, способ их получения, фармацевтическая композиция и способ лечения опухоли
US5393886A (en) * 1993-05-05 1995-02-28 The Du Pont Merck Pharmaceutical Company Intermediates for the synthesis of anthrapyrazolone anticancer agents
US5596097A (en) * 1994-03-08 1997-01-21 The University Of Vermont Hetero-annulated indazoles
IT1277576B1 (it) * 1995-09-13 1997-11-11 Boehringer Mannheim Italia 2-2-(2-idrossietil) ammino etil -5- 2-metilammino etil ammino indazolo 4,3-gh isochinolin-6 (2h)-one come agente antitumorale
US20100233689A1 (en) 2007-03-22 2010-09-16 The General Hospital Corporation Pyrazoloanthrone and derivatives thereof for the treatment of cancer expressing 'mullerian inhibiting substance' type ii receptor (misrii) and of excess androgen states

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH191142A (de) * 1936-02-07 1937-05-31 Chem Ind Basel Verfahren zur Herstellung eines Anthrachinonderivates.
GB470475A (en) * 1936-02-14 1937-08-16 Of Chemical Industry Soc Manufacture of dyestuffs and intermediate products
US2518150A (en) * 1946-02-01 1950-08-08 Ciba Ltd Vat dyestuffs
DE2558812C2 (de) * 1975-12-27 1987-04-30 Hoechst Ag, 6230 Frankfurt Photopolymerisierbares Gemisch

Also Published As

Publication number Publication date
PH20906A (en) 1987-05-27
HU195779B (en) 1988-07-28
DK159429B (da) 1990-10-15
ES8507503A1 (es) 1985-09-01
PT77088A (en) 1983-08-01
NO160000B (no) 1988-11-21
IE56782B1 (en) 1991-12-18
FI82932B (fi) 1991-01-31
NZ205001A (en) 1986-09-10
AR240315A1 (es) 1990-03-30
IL69211A (en) 1987-01-30
DK160251B (da) 1991-02-18
DK329683D0 (da) 1983-07-18
ES529577A0 (es) 1985-09-01
NO832659L (no) 1984-01-24
DK329683A (da) 1984-01-24
CA1251442C (da) 1989-03-21
JPH07179389A (ja) 1995-07-18
JPH072719B2 (ja) 1995-01-18
FI832638A0 (fi) 1983-07-20
AU1681083A (en) 1984-01-26
IL69211A0 (en) 1983-11-30
FI82932C (fi) 1991-05-10
EP0103381B1 (en) 1987-09-23
ES8507502A1 (es) 1985-09-01
EP0103381A1 (en) 1984-03-21
IE831622L (en) 1984-01-23
GR79610B (da) 1984-10-31
FI832638A7 (fi) 1984-01-24
DK160251C (da) 1991-07-22
DK430289D0 (da) 1989-08-31
KR900005026B1 (ko) 1990-07-18
DK430289A (da) 1989-08-31
DE3373811D1 (en) 1987-10-29
NO160000C (no) 1989-03-01
AU549659B2 (en) 1986-02-06
JPH07110829B2 (ja) 1995-11-29
DK430389A (da) 1989-08-31
DK159429C (da) 1991-03-18
DK159849B (da) 1990-12-17
ES524380A0 (es) 1985-04-16
DK430389D0 (da) 1989-08-31
ES8504731A1 (es) 1985-04-16
PT77088B (en) 1986-02-12
KR840005431A (ko) 1984-11-12
JPS5951268A (ja) 1984-03-24
ES529578A0 (es) 1985-09-01
CA1230115A (en) 1987-12-08

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Legal Events

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PUP Patent expired