DK161430C - Fed O/V creme til topisk legemsanvendelse - Google Patents

Fed O/V creme til topisk legemsanvendelse Download PDF

Info

Publication number: DK161430C
Authority: DK; Denmark
Prior art keywords: cream; weight; fat; fatty; water
Prior art date: 1981-07-02

Application number

DK295082A

Other languages

Danish (da)

English (en)

Other versions

DK295082A (da

DK161430B (da

Inventor

Adrianus Pieter Molenaar

Original Assignee

Yamanouchi Europ Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-07-02

Filing date

1982-06-30

Publication date

1997-02-03

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10522970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK161430(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1982-06-30 Application filed by Yamanouchi Europ Bv filed Critical Yamanouchi Europ Bv

1983-01-03 Publication of DK295082A publication Critical patent/DK295082A/da

1991-07-08 Publication of DK161430B publication Critical patent/DK161430B/da

1997-02-03 Application granted granted Critical

1997-02-03 Publication of DK161430C publication Critical patent/DK161430C/da

Links

239000006071 cream Substances 0.000 title claims abstract description 84
230000000699 topical effect Effects 0.000 title claims abstract description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 31
239000003814 drug Substances 0.000 claims abstract description 19
229940124597 therapeutic agent Drugs 0.000 claims abstract description 18
239000004094 surface-active agent Substances 0.000 claims abstract description 11
239000000463 material Substances 0.000 claims abstract description 9
239000002736 nonionic surfactant Substances 0.000 claims abstract description 9
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 18
OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 claims description 12
150000002191 fatty alcohols Chemical class 0.000 claims description 7
229940057995 liquid paraffin Drugs 0.000 claims description 7
239000012188 paraffin wax Substances 0.000 claims description 7
IQXJCCZJOIKIAD-UHFFFAOYSA-N 1-(2-methoxyethoxy)hexadecane Chemical group CCCCCCCCCCCCCCCCOCCOC IQXJCCZJOIKIAD-UHFFFAOYSA-N 0.000 claims description 6
229950009789 cetomacrogol 1000 Drugs 0.000 claims description 6
150000002148 esters Chemical class 0.000 claims description 6
239000001509 sodium citrate Substances 0.000 claims description 6
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 6
239000006172 buffering agent Substances 0.000 claims description 5
239000003755 preservative agent Substances 0.000 claims description 5
NUZWLKWWNNJHPT-UHFFFAOYSA-N anthralin Chemical compound C1C2=CC=CC(O)=C2C(=O)C2=C1C=CC=C2O NUZWLKWWNNJHPT-UHFFFAOYSA-N 0.000 claims description 4
229960002311 dithranol Drugs 0.000 claims description 4
230000002335 preservative effect Effects 0.000 claims description 4
150000003431 steroids Chemical class 0.000 claims description 2
239000000203 mixture Substances 0.000 abstract description 21
239000003921 oil Substances 0.000 description 20
235000019198 oils Nutrition 0.000 description 19
239000002674 ointment Substances 0.000 description 18
239000003925 fat Substances 0.000 description 17
235000019197 fats Nutrition 0.000 description 17
JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 17
239000000839 emulsion Substances 0.000 description 16
239000012071 phase Substances 0.000 description 13
238000000034 method Methods 0.000 description 12
239000003995 emulsifying agent Substances 0.000 description 10
229960000890 hydrocortisone Drugs 0.000 description 9
239000007788 liquid Substances 0.000 description 8
238000002360 preparation method Methods 0.000 description 8
150000001875 compounds Chemical class 0.000 description 7
238000003756 stirring Methods 0.000 description 6
FJQXCDYVZAHXNS-UHFFFAOYSA-N methadone hydrochloride Chemical compound Cl.C=1C=CC=CC=1C(CC(C)N(C)C)(C(=O)CC)C1=CC=CC=C1 FJQXCDYVZAHXNS-UHFFFAOYSA-N 0.000 description 5
239000000243 solution Substances 0.000 description 5
CFKMVGJGLGKFKI-UHFFFAOYSA-N 4-chloro-m-cresol Chemical compound CC1=CC(O)=CC=C1Cl CFKMVGJGLGKFKI-UHFFFAOYSA-N 0.000 description 4
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 4
239000007864 aqueous solution Substances 0.000 description 4
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 4
238000002474 experimental method Methods 0.000 description 4
235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 4
229920000053 polysorbate 80 Polymers 0.000 description 4
FERIUCNNQQJTOY-UHFFFAOYSA-M Butyrate Chemical compound CCCC([O-])=O FERIUCNNQQJTOY-UHFFFAOYSA-M 0.000 description 3
FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Natural products CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 3
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
239000008346 aqueous phase Substances 0.000 description 3
239000006210 lotion Substances 0.000 description 3
238000002156 mixing Methods 0.000 description 3
239000002245 particle Substances 0.000 description 3
239000007787 solid Substances 0.000 description 3
VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical group CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
239000005711 Benzoic acid Substances 0.000 description 2
244000060011 Cocos nucifera Species 0.000 description 2
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
235000019483 Peanut oil Nutrition 0.000 description 2
229920001214 Polysorbate 60 Polymers 0.000 description 2
229910000147 aluminium phosphate Inorganic materials 0.000 description 2
235000010233 benzoic acid Nutrition 0.000 description 2
229960004365 benzoic acid Drugs 0.000 description 2
239000000872 buffer Substances 0.000 description 2
229960002242 chlorocresol Drugs 0.000 description 2
239000003240 coconut oil Substances 0.000 description 2
235000019864 coconut oil Nutrition 0.000 description 2
239000008367 deionised water Substances 0.000 description 2
229910021641 deionized water Inorganic materials 0.000 description 2
230000000694 effects Effects 0.000 description 2
BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 description 2
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
239000000312 peanut oil Substances 0.000 description 2
235000019271 petrolatum Nutrition 0.000 description 2
239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 2
229940068968 polysorbate 80 Drugs 0.000 description 2
239000008213 purified water Substances 0.000 description 2
208000017520 skin disease Diseases 0.000 description 2
239000001488 sodium phosphate Substances 0.000 description 2
229910000162 sodium phosphate Inorganic materials 0.000 description 2
235000010199 sorbic acid Nutrition 0.000 description 2
239000004334 sorbic acid Substances 0.000 description 2
229940075582 sorbic acid Drugs 0.000 description 2
239000003549 soybean oil Substances 0.000 description 2
235000012424 soybean oil Nutrition 0.000 description 2
HLZKNKRTKFSKGZ-UHFFFAOYSA-N tetradecan-1-ol Chemical compound CCCCCCCCCCCCCCO HLZKNKRTKFSKGZ-UHFFFAOYSA-N 0.000 description 2
239000002562 thickening agent Substances 0.000 description 2
YNDXUCZADRHECN-JNQJZLCISA-N triamcinolone acetonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O YNDXUCZADRHECN-JNQJZLCISA-N 0.000 description 2
229960002117 triamcinolone acetonide Drugs 0.000 description 2
RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 2
235000015112 vegetable and seed oil Nutrition 0.000 description 2
239000008158 vegetable oil Substances 0.000 description 2
239000003981 vehicle Substances 0.000 description 2
RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 description 1
CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
229920000742 Cotton Polymers 0.000 description 1
206010013786 Dry skin Diseases 0.000 description 1
244000068988 Glycine max Species 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
201000004681 Psoriasis Diseases 0.000 description 1
239000002253 acid Substances 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 description 1
229940051879 analgesics and antipyretics salicylic acid and derivative Drugs 0.000 description 1
239000003242 anti bacterial agent Substances 0.000 description 1
239000002260 anti-inflammatory agent Substances 0.000 description 1
229940088710 antibiotic agent Drugs 0.000 description 1
239000002246 antineoplastic agent Substances 0.000 description 1
239000003963 antioxidant agent Substances 0.000 description 1
230000003078 antioxidant effect Effects 0.000 description 1
239000007900 aqueous suspension Substances 0.000 description 1
230000001580 bacterial effect Effects 0.000 description 1
230000003115 biocidal effect Effects 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
239000004927 clay Substances 0.000 description 1
230000000052 comparative effect Effects 0.000 description 1
BMCQMVFGOVHVNG-TUFAYURCSA-N cortisol 17-butyrate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)CO)(OC(=O)CCC)[C@@]1(C)C[C@@H]2O BMCQMVFGOVHVNG-TUFAYURCSA-N 0.000 description 1
125000000017 cortisol group Chemical group 0.000 description 1
239000002537 cosmetic Substances 0.000 description 1
239000002385 cottonseed oil Substances 0.000 description 1
235000012343 cottonseed oil Nutrition 0.000 description 1
229940127089 cytotoxic agent Drugs 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
208000035475 disorder Diseases 0.000 description 1
238000001035 drying Methods 0.000 description 1
238000005516 engineering process Methods 0.000 description 1
239000003349 gelling agent Substances 0.000 description 1
229940075507 glyceryl monostearate Drugs 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 1
229960004068 hexachlorophene Drugs 0.000 description 1
229960001524 hydrocortisone butyrate Drugs 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
150000002497 iodine compounds Chemical class 0.000 description 1
239000004310 lactic acid Substances 0.000 description 1
235000014655 lactic acid Nutrition 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
229960000907 methylthioninium chloride Drugs 0.000 description 1
239000002480 mineral oil Substances 0.000 description 1
239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
229940043348 myristyl alcohol Drugs 0.000 description 1
239000007764 o/w emulsion Substances 0.000 description 1
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
230000003647 oxidation Effects 0.000 description 1
238000007254 oxidation reaction Methods 0.000 description 1
229940083256 peripheral vasodilators nicotinic acid and derivative Drugs 0.000 description 1
230000000704 physical effect Effects 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 description 1
235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 description 1
229920001296 polysiloxane Polymers 0.000 description 1
229940113124 polysorbate 60 Drugs 0.000 description 1
229930002330 retinoic acid Natural products 0.000 description 1
239000001540 sodium lactate Substances 0.000 description 1
235000011088 sodium lactate Nutrition 0.000 description 1
229940005581 sodium lactate Drugs 0.000 description 1
241000894007 species Species 0.000 description 1
150000003464 sulfur compounds Chemical class 0.000 description 1
239000000725 suspension Substances 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
239000010409 thin film Substances 0.000 description 1
229960001727 tretinoin Drugs 0.000 description 1
239000008313 unguentum cetomacrogolis Substances 0.000 description 1
238000011179 visual inspection Methods 0.000 description 1
238000005406 washing Methods 0.000 description 1
239000001993 wax Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Dermatology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Adhesive Tapes (AREA)
Confectionery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Dairy Products (AREA)

DK295082A 1981-07-02 1982-06-30 Fed O/V creme til topisk legemsanvendelse DK161430C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8120471		1981-07-02
GB8120471		1981-07-02

Publications (3)

Publication Number	Publication Date
DK295082A DK295082A (da)	1983-01-03
DK161430B DK161430B (da)	1991-07-08
DK161430C true DK161430C (da)	1997-02-03

Family

ID=10522970

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK295082A DK161430C (da)	1981-07-02	1982-06-30	Fed O/V creme til topisk legemsanvendelse

Country Status (13)

Country	Link
EP (1)	EP0069423B2 (de)
AT (1)	ATE33760T1 (de)
AU (1)	AU555467B2 (de)
CA (1)	CA1200504A (de)
DE (1)	DE3278389D1 (de)
DK (1)	DK161430C (de)
ES (1)	ES8307493A1 (de)
FI (1)	FI79941C (de)
GR (1)	GR76547B (de)
IE (1)	IE54099B1 (de)
NO (1)	NO164457C (de)
NZ (1)	NZ200918A (de)
PT (1)	PT75088B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS59137408A (ja) *	1983-01-27	1984-08-07	Taisho Pharmaceut Co Ltd	軟膏
US4868168A (en) *	1987-11-13	1989-09-19	E. R. Squibb & Sons, Inc.	Steroid ointment formulation
FR2660554B1 (fr) *	1990-04-05	1992-07-03	Oreal	Composition cosmetique ou dermo-pharmaceutique aqueuse contenant en suspension des spherouides hydrates d'une substance lipidique hydrophile.
CN1102410C (zh) *	1993-10-22	2003-03-05	史密丝克莱恩比彻姆公司	莫匹罗星钙盐的乳膏组合物
CO4910145A1 (es) *	1996-10-01	2000-04-24	Smithkline Beecham Corp	Uso
WO1998014189A1 (en) *	1996-10-01	1998-04-09	Smithkline Beecham Corporation	Use of mupirocin for the manufacture of a medicament for the treatment of bacterial infections associated with colonisation of the nasopharynx by pathogenic organisms
WO1999012520A1 (en) *	1997-09-11	1999-03-18	Smithkline Beecham Plc	Compositions adapted for prolonged residence in the nasal pharynx

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL267783A (de) *		1900-01-01
NL271464A (de) *
US3758686A (en) *	1971-12-07	1973-09-11	American Cyanamid Co	Method of using steroid acetonides
FR2258165A1 (en) *	1974-01-21	1975-08-18	Petrolite Corp	Thixotropic emulsions with a high internal phase content - contg. cosmetics, medicaments, foodstuffs or household products
JPS5850964B2 (ja) *	1978-03-07	1983-11-14	東興薬品工業株式会社	ステロイド含有クリ−ム製剤およびその製造方法
SE8004580L (sv) *	1980-06-19	1981-12-20	Draco Ab	Farmaceutisk beredning

1982
- 1982-06-11 NZ NZ200918A patent/NZ200918A/en unknown
- 1982-06-16 CA CA000405256A patent/CA1200504A/en not_active Expired
- 1982-06-18 AU AU85017/82A patent/AU555467B2/en not_active Expired
- 1982-06-21 PT PT75088A patent/PT75088B/pt unknown
- 1982-06-29 EP EP82200803A patent/EP0069423B2/de not_active Expired - Lifetime
- 1982-06-29 AT AT82200803T patent/ATE33760T1/de not_active IP Right Cessation
- 1982-06-29 DE DE8282200803T patent/DE3278389D1/de not_active Expired
- 1982-06-30 DK DK295082A patent/DK161430C/da not_active IP Right Cessation
- 1982-06-30 IE IE1566/82A patent/IE54099B1/en active IP Right Review Request
- 1982-06-30 NO NO822276A patent/NO164457C/no not_active IP Right Cessation
- 1982-06-30 FI FI822331A patent/FI79941C/fi not_active IP Right Cessation
- 1982-07-01 GR GR68616A patent/GR76547B/el unknown
- 1982-07-02 ES ES513664A patent/ES8307493A1/es not_active Expired

Also Published As

Publication number	Publication date
DK295082A (da)	1983-01-03
DE3278389D1 (en)	1988-06-01
PT75088A (en)	1982-07-01
EP0069423B1 (de)	1988-04-27
CA1200504A (en)	1986-02-11
EP0069423B2 (de)	1998-04-22
NO164457C (no)	1990-10-10
FI79941C (fi)	1990-04-10
DK161430B (da)	1991-07-08
AU555467B2 (en)	1986-09-25
NO164457B (no)	1990-07-02
NO822276L (no)	1983-01-03
IE821566L (en)	1983-01-02
IE54099B1 (en)	1989-06-21
ATE33760T1 (de)	1988-05-15
NZ200918A (en)	1985-07-31
ES513664A0 (es)	1983-08-01
EP0069423A1 (de)	1983-01-12
GR76547B (de)	1984-08-10
FI79941B (fi)	1989-12-29
PT75088B (en)	1983-12-28
ES8307493A1 (es)	1983-08-01
FI822331L (fi)	1983-01-03
AU8501782A (en)	1983-01-06
FI822331A0 (fi)	1982-06-30

Legal Events

Date	Code	Title	Description
2002-07-22	PUP	Patent expired

Publication	Publication Date	Title
US6004580A (en)	1999-12-21	Pharmaceutical compositions derived from microemulsion-based gels
DE69624212T2 (de)	2003-06-12	Multiple Emulsion des Typs O/W/O und Verfahren zu ihrer Herstellung
DE2954558C2 (de)	1990-05-17
DE2418345C2 (de)	1985-04-25	Pharmazeutisches Mittel für äußerliche Anwendung an menschlicher Haut
DE69433386T2 (de)	2004-10-14	Propylenglykolstearat-vesikel
DE69600008T2 (de)	1997-07-03	Säurezusammensetzung basiert auf Lipidvesikeln sowie seiner Anwendung zur topischen Verwendung
EP0098566B1 (de)	1991-08-21	Kortikoidhaltige Zubereitung zur topischen Applikation
DE2612330C2 (de)	1988-04-28
JP2002500632A (ja)	2002-01-08	アルキルポリグリコシド及び脂肪アルコールに基づいた組成物、並びに、その使用
EP0540857B1 (de)	1997-09-17	Verfahren zur Herstellung von stabilen, komplexen Emulsionssystemen des Typs Wasser-Öl-Wasser und Verwendung als kosmetische Präparate
ITMI20081339A1 (it)	2010-01-24	Oli modificati ed emulsioni multiple
DE3124698A1 (de)	1982-07-08	Oertlich anwendbares praeparat fuer die behandlung von akne
DE69116257T2 (de)	1996-06-27	Wässerige emulsion mit nicht steroidhaltigen entzündungshemmenden schmerzmitteln
DK161430B (da)	1991-07-08	Fed o/v creme til topisk legemsanvendelse
DE2514873A1 (de)	1976-10-14	Salbengrundlage
US4871777A (en)	1989-10-03	Emulsifying compositions for suppository bases and suppositories produced therefrom
JPS5946123A (ja)	1984-03-15	ゲル状エマルシヨン及び水中油型エマルシヨンの製造法
JPS6312653B2 (de)	1988-03-22
US5635497A (en)	1997-06-03	Topical application compositions
DE1210127B (de)	1966-02-03	Verfahren zur Stabilisierung von lipophile Substanzen enthaltenden waessrigen Loesungen
DK161429B (da)	1991-07-08	Fremgangsmaade til fremstilling af et kosmetisk middel
JPH0316174B2 (de)	1991-03-04
JPH0261442B2 (de)	1990-12-20
DE2646435A1 (de)	1978-04-20	Verfahren zur herstellung einer stabilen oel/wasser-emulsion und diese enthaltende kosmetische mittel
EP0098568B1 (de)	1991-08-28	Kortikoidhaltige Zubereitungen zur topischen Applikation