DK1616007T3 - Inhibitorproteiner af en protease og anvendelse heraf - Google Patents

Inhibitorproteiner af en protease og anvendelse heraf

Info

Publication number: DK1616007T3
Authority: DK; Denmark
Prior art keywords: protease; inhibitor proteins; inhibitor; proteins
Prior art date: 2003-04-04

Application number

DK04725742.3T

Other languages

English (en)

Inventor

David Deperthes

Sylvain Cloutier

Original Assignee

Univ Lausanne

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-04

Filing date

2004-04-05

Publication date

2013-10-28

2004-04-05 Application filed by Univ Lausanne filed Critical Univ Lausanne

2013-10-28 Application granted granted Critical

2013-10-28 Publication of DK1616007T3 publication Critical patent/DK1616007T3/da

Links

108091005804 Peptidases Proteins 0.000 title 1
239000004365 Protease Substances 0.000 title 1
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title 1
108091006086 inhibitor proteins Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Oncology (AREA)
Transplantation (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK04725742.3T 2003-04-04 2004-04-05 Inhibitorproteiner af en protease og anvendelse heraf DK1616007T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US46034503P	2003-04-04	2003-04-04
PCT/IB2004/001040 WO2004087912A1 (en)	2003-04-04	2004-04-05	Inhibitor proteins of a protease and use thereof

Publications (1)

Publication Number	Publication Date
DK1616007T3 true DK1616007T3 (da)	2013-10-28

Family

ID=33131923

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04725742.3T DK1616007T3 (da)	2003-04-04	2004-04-05	Inhibitorproteiner af en protease og anvendelse heraf

Country Status (19)

Country	Link
US (1)	US8975370B2 (da)
EP (1)	EP1616007B1 (da)
JP (1)	JP4754478B2 (da)
KR (1)	KR101296367B1 (da)
CN (1)	CN1798838B (da)
AU (1)	AU2004225718B2 (da)
BR (1)	BRPI0409557B8 (da)
CA (1)	CA2521410C (da)
CY (1)	CY1114526T1 (da)
DK (1)	DK1616007T3 (da)
ES (1)	ES2431548T3 (da)
IL (1)	IL171158A (da)
MX (1)	MXPA05010574A (da)
NO (1)	NO334459B1 (da)
PL (1)	PL1616007T3 (da)
PT (1)	PT1616007E (da)
SG (1)	SG161106A1 (da)
SI (1)	SI1616007T1 (da)
WO (1)	WO2004087912A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003064605A2 (en)	2002-01-28	2003-08-07	Ambion, Inc.	Crude biological derivatives competent for nucleic acid detection
WO2006090282A2 (en) *	2005-02-28	2006-08-31	Universite De Lausanne	Recombinant inhibitor proteins of an hk14 protease and use thereof
US7964350B1 (en)	2007-05-18	2011-06-21	Applied Biosystems, Llc	Sample preparation for in situ nucleic acid analysis
AU2009207394B2 (en) *	2008-01-21	2015-01-22	Dermadis Sa	Use of serine protease inhibitors in the treatment of skin diseases
EP2955233A1 (en)	2008-12-19	2015-12-16	Life Technologies Corporation	Proteinase K inhibitors, methods and compositions therefor
CN102448473A (zh) *	2009-03-10	2012-05-09	Med发现公司	丝氨酸蛋白酶抑制剂在治疗嗜中性粒细胞减少症中的用途
SG195083A1 (en) *	2011-05-26	2013-12-30	Baxter Int	Solid phase-bound elastase-binding assay for the measurement of alpha1,-antitrypsin activity
CN103044542B (zh) *	2012-08-17	2015-08-19	常熟理工学院	鲫鱼卵中丝氨酸蛋白酶抑制剂及其基因和应用
CN117169519B (zh) *	2023-10-26	2024-01-30	艾康生物技术(杭州)有限公司	用于检测样本中tt3和/或tt4的解离剂和试剂盒

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3773919A (en)	1969-10-23	1973-11-20	Du Pont	Polylactide-drug mixtures
WO1990010649A1 (en)	1989-03-06	1990-09-20	The Board Of Regents Of The University Of Texas System	Serpin resistant chymotrypsin superfamily proteases, particularly pai-1 resistant +-pa, complementary inhibitor mutants; compositions; genes; expression
US5827662A (en) *	1989-06-23	1998-10-27	The Trustees Of The University Of Pennsylvania	Methods for detecting genetic mutations resulting in protease inhibitor insufficiencies
US5723316A (en) *	1989-06-23	1998-03-03	Trustees Of The University Of Pennsylvania	α-1-antichymotrypsin analogues having chymase inhibiting activity
US5612194A (en) *	1989-06-23	1997-03-18	Trustees Of The University Of Pennsylvania	Methods of producing effective recombinant serine protease inhibitors and uses of these inhibitors
US6057287A (en)	1994-01-11	2000-05-02	Dyax Corp.	Kallikrein-binding "Kunitz domain" proteins and analogues thereof
CA2180950C (en)	1994-01-11	2005-03-29	William Markland	Kallikrein-inhibiting "kunitz domain" proteins and analogues thereof
US6284873B1 (en)	1999-03-12	2001-09-04	Hybritech Incorporated	Complex of human kallikrein 2 (hK2) and protease inhibitor-6 (PI-6) in prostate tumor tissue and methods of using the complex

2004
- 2004-04-05 US US10/552,786 patent/US8975370B2/en active Active
- 2004-04-05 WO PCT/IB2004/001040 patent/WO2004087912A1/en not_active Ceased
- 2004-04-05 ES ES04725742T patent/ES2431548T3/es not_active Expired - Lifetime
- 2004-04-05 JP JP2006506440A patent/JP4754478B2/ja not_active Expired - Lifetime
- 2004-04-05 PT PT47257423T patent/PT1616007E/pt unknown
- 2004-04-05 MX MXPA05010574A patent/MXPA05010574A/es active IP Right Grant
- 2004-04-05 DK DK04725742.3T patent/DK1616007T3/da active
- 2004-04-05 CN CN2004800152687A patent/CN1798838B/zh not_active Expired - Lifetime
- 2004-04-05 EP EP04725742.3A patent/EP1616007B1/en not_active Expired - Lifetime
- 2004-04-05 BR BRPI0409557-0 patent/BRPI0409557B8/pt not_active IP Right Cessation
- 2004-04-05 SI SI200432098T patent/SI1616007T1/sl unknown
- 2004-04-05 KR KR1020057018938A patent/KR101296367B1/ko not_active Expired - Lifetime
- 2004-04-05 CA CA2521410A patent/CA2521410C/en not_active Expired - Lifetime
- 2004-04-05 SG SG200718462-5A patent/SG161106A1/en unknown
- 2004-04-05 PL PL04725742T patent/PL1616007T3/pl unknown
- 2004-04-05 AU AU2004225718A patent/AU2004225718B2/en not_active Expired
2005
- 2005-09-28 IL IL171158A patent/IL171158A/en active IP Right Grant
- 2005-11-04 NO NO20055210A patent/NO334459B1/no unknown
2013
- 2013-10-23 CY CY20131100937T patent/CY1114526T1/el unknown

Also Published As

Publication number	Publication date
AU2004225718B2 (en)	2009-11-05
NO334459B1 (no)	2014-03-10
MXPA05010574A (es)	2006-03-09
ES2431548T3 (es)	2013-11-26
CA2521410A1 (en)	2004-10-14
JP2006523097A (ja)	2006-10-12
WO2004087912A1 (en)	2004-10-14
PT1616007E (pt)	2013-10-28
KR101296367B1 (ko)	2013-08-14
CN1798838A (zh)	2006-07-05
WO2004087912A8 (en)	2005-01-20
SI1616007T1 (sl)	2013-12-31
KR20060010740A (ko)	2006-02-02
CA2521410C (en)	2014-06-03
AU2004225718A1 (en)	2004-10-14
EP1616007B1 (en)	2013-07-24
US20060269536A1 (en)	2006-11-30
PL1616007T3 (pl)	2013-12-31
US8975370B2 (en)	2015-03-10
BRPI0409557B8 (pt)	2021-05-25
BRPI0409557A (pt)	2006-04-18
NO20055210L (no)	2005-12-23
SG161106A1 (en)	2010-05-27
NO20055210D0 (no)	2005-11-04
JP4754478B2 (ja)	2011-08-24
IL171158A (en)	2011-05-31
CY1114526T1 (el)	2016-10-05
CN1798838B (zh)	2012-01-04
BRPI0409557B1 (pt)	2019-07-23
EP1616007A1 (en)	2006-01-18

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DK1567529T4 (da)	2021-05-10	Pseudopolymorfe former af en hiv-proteaseinhibitor
JP2005511541A5 (ja)	2006-01-05	プロリン後切断プロテアーゼの阻害剤
DK1673460T3 (da)	2013-02-04	Rekombinante vacciner og anvendelse af disse
DK1483284T3 (da)	2006-10-16	Selektive dipeptidinhibitorer af kallikrein
ATE413395T1 (de)	2008-11-15	N-substituierte pyrazolyl-amidyl-benzimidazolyl-c-kit-inhibitor n
DK1501508T3 (da)	2007-05-21	Inhibitorer af histondeatylase
DK2075000T3 (da)	2015-09-14	Kombination af azelastin og ciclesonid
NO20034044D0 (no)	2003-09-12	Metallproteinase-inhibitorer
DE602005019971D1 (de)	2010-04-29	Inhibitoren von cysteinprotease
CY2012007I2 (el)	2014-07-02	Πεπτιδομιμητικοι αναστολεις πρωτεασης
NO20042719L (no)	2004-06-28	Substituerte 2-amino-cykloalkankarboksamider og deres anvendelse som protease-inhibitorer
IS8305A (is)	2006-02-16	Bindandi smíðar og aðferðir við notkun þeirra
DK1458447T3 (da)	2010-01-18	Kombination af cytokrom-p450-beroende proteasinhibitorer
NO20032084D0 (no)	2003-05-09	Skifer-hydrerings-hemmende middel og fremgangsmåte for anvendelse derav
NO20034032L (no)	2003-11-10	Metallproteinase-inhibitorer
DK1470732T3 (da)	2019-12-02	Fremskaffelse af lokaliseringsinformation
NO20033854D0 (no)	2003-09-01	N-but-3-enyl-norbuprenorfin og fremgangsmåter for anvendelse
EP1673336A4 (en)	2007-05-30	CATHEPSINCYSTEINPROTEASEHEMMER
ITMI20021391A1 (it)	2003-12-29	Nitroderivati di inibitori della cicloossigenasi-2
DK1601744T3 (da)	2012-08-20	Forgasningsapparat og fremgangsmåde
DK2305689T3 (da)	2014-07-14	Syntese af naturligt forekommende ecteinascidiner og relateredeforbindelser
NO20025786L (no)	2003-02-12	Protaseinhibitorer