DK164641C - Anvendelse af acetyl-l-carnitin og farmaologisk acceptable salte deraf til fremstilling af laegemidler til behandling af perifere neuropathier - Google Patents

Anvendelse af acetyl-l-carnitin og farmaologisk acceptable salte deraf til fremstilling af laegemidler til behandling af perifere neuropathier

Info

Publication number
DK164641C
DK164641C DK403587A DK403587A DK164641C DK 164641 C DK164641 C DK 164641C DK 403587 A DK403587 A DK 403587A DK 403587 A DK403587 A DK 403587A DK 164641 C DK164641 C DK 164641C
Authority
DK
Denmark
Prior art keywords
carnitine
acetyl
pharmaceuticals
preparation
treatment
Prior art date
Application number
DK403587A
Other languages
English (en)
Other versions
DK403587A (da
DK403587D0 (da
DK164641B (da
Inventor
Menotti Calvani
Luigi Mosconi
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of DK403587D0 publication Critical patent/DK403587D0/da
Publication of DK403587A publication Critical patent/DK403587A/da
Publication of DK164641B publication Critical patent/DK164641B/da
Application granted granted Critical
Publication of DK164641C publication Critical patent/DK164641C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
DK403587A 1986-08-04 1987-08-03 Anvendelse af acetyl-l-carnitin og farmaologisk acceptable salte deraf til fremstilling af laegemidler til behandling af perifere neuropathier DK164641C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT48358/86A IT1196564B (it) 1986-08-04 1986-08-04 Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche
IT4835886 1986-08-04

Publications (4)

Publication Number Publication Date
DK403587D0 DK403587D0 (da) 1987-08-03
DK403587A DK403587A (da) 1988-02-05
DK164641B DK164641B (da) 1992-07-27
DK164641C true DK164641C (da) 1992-12-14

Family

ID=11266089

Family Applications (1)

Application Number Title Priority Date Filing Date
DK403587A DK164641C (da) 1986-08-04 1987-08-03 Anvendelse af acetyl-l-carnitin og farmaologisk acceptable salte deraf til fremstilling af laegemidler til behandling af perifere neuropathier

Country Status (11)

Country Link
US (1) US4751242A (da)
EP (1) EP0256999B1 (da)
JP (1) JPH085786B2 (da)
AT (1) ATE70439T1 (da)
CA (1) CA1298197C (da)
DE (1) DE3775301D1 (da)
DK (1) DK164641C (da)
ES (1) ES2039262T3 (da)
GR (1) GR3003405T3 (da)
IT (1) IT1196564B (da)
ZA (1) ZA875643B (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1224842B (it) * 1988-12-27 1990-10-24 Sigma Tau Ind Farmaceuti Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
US5641764A (en) * 1989-03-31 1997-06-24 Peter Maccallum Institute Halogenated DNA ligand radiosensitizers for cancer therapy
IT1230141B (it) * 1989-05-03 1991-10-14 Fidia Spa Impiego di derivati della fosfatidil carnitina per la preparazione di composizioni farmaceutiche aventi attivita' nella terapia delle patologie dell'uomo associate con un danno neuronale.
IT1244636B (it) * 1991-01-04 1994-08-08 Sigma Tau Ind Farmaceuti Uso dell'acetil l-carnitina nel trattamento terapeutico del coma e composizioni farmaceutiche utili in tale trattamento.
IT1245699B (it) * 1991-05-29 1994-10-14 Sigma Tau Ind Farmaceuti Derivati della l-carnitina quali agenti terapeutici per il trattamento delle miopatie, della degenarazione neuronale e per inibire la proteolisi
IT1263004B (it) * 1992-10-08 1996-07-23 Sigma Tau Ind Farmaceuti Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti.
IT1276225B1 (it) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per
IT1291127B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica
IT1294227B1 (it) * 1997-08-01 1999-03-24 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l-carnitina e alcoli alifatici a lunga catena utile per la prevenzione
IT1298487B1 (it) * 1997-12-19 2000-01-10 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale,
JPH11298323A (ja) 1998-04-16 1999-10-29 Nec Yamagata Ltd 高速ロックアップｐｌｌ回路
US20030199535A1 (en) * 1998-07-30 2003-10-23 Claudio Cavazza Method for preventing and/or treating peripheral neuropathies induced by the administration of an anticancer agent
DE69923322T2 (de) * 1998-07-30 2005-12-22 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Verwendung von propionyl-l-carnitin und acetyl-l-carnitin zur herstellung von arzneimittel mit antikrebs wirkung
IT1306178B1 (it) * 1999-07-27 2001-05-30 Sigma Tau Ind Farmaceuti Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da
WO2001021208A1 (en) * 1999-09-23 2001-03-29 Juvenon Corporation Nutritional supplement for increased energy and stamina
US6562869B1 (en) * 1999-09-23 2003-05-13 Juvenon, Inc. Nutritional supplement for increased energy and stamina
ITRM20010294A1 (it) * 2001-05-29 2002-11-29 Sigma Tau Ind Farmaceuti Uso della acetil l-carnetina in associazione con la biotina per il trattamento di pazienti affetti da diabete mellito di tipo ii insulino re
ITRM20010293A1 (it) * 2001-05-29 2002-11-29 Sigma Tau Ind Farmaceuti Uso della acetil-l-carnetina per la preparazione di un medicamento per la prevenzione del dolore.
US8173618B2 (en) * 2003-07-25 2012-05-08 University Of Massachusetts Formulations for reducing neuronal degeneration
ITRM20040327A1 (it) * 2004-07-01 2004-10-01 Sigma Tau Ind Farmaceuti Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.
PL1874288T3 (pl) * 2005-04-26 2013-11-29 Alfasigma Spa Acetylo-L-karnityna do zapobiegania bolesnej obwodowej neuropatii cukrzycowej
US8569366B2 (en) * 2005-04-26 2013-10-29 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Acetyl L-carnitine for prevention of painful peripheral neuropathy in patients with type 2 diabetes
US20080161604A1 (en) * 2005-04-26 2008-07-03 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Acetyl L-Carnitine For Preventing Painful Peripheral Diabetic Neuropathy
JP2006347935A (ja) * 2005-06-15 2006-12-28 Masanori Ogata 炎症性サイトカインの産生が関与する疾患の予防及び／又は治療のための医薬
US8597640B2 (en) * 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
EP2582368B1 (en) 2010-06-16 2018-05-09 Alfasigma S.p.A. Acetyl-carnitine for use in a method for increasing neurogenesis in neural tissue
EP3277273B1 (en) * 2015-03-31 2020-02-26 Kolinpharma S.p.A. A composition for the treatment of neuropathies and/or neuropathic pain
WO2017139415A2 (en) * 2016-02-11 2017-08-17 Qiagen Waltham, Inc. Scavenger compounds for improved sequencing-by-synthesis
KR20230011999A (ko) 2020-05-15 2023-01-25 알파시그마 에스.피.에이. 메틸폴레이트를 포함하는 조성물
IT202200022437A1 (it) 2022-11-02 2024-05-02 Chiesi Italia S P A Composizione farmaceutica comprendente l-acetilcarnitina e beta-cariofillene

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4346107A (en) * 1979-02-12 1982-08-24 Claudio Cavazza Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism

Also Published As

Publication number Publication date
EP0256999A3 (en) 1989-05-31
GR3003405T3 (en) 1993-02-17
JPS6344522A (ja) 1988-02-25
EP0256999A2 (en) 1988-02-24
DE3775301D1 (de) 1992-01-30
IT1196564B (it) 1988-11-16
ZA875643B (en) 1988-11-30
IT8648358A0 (it) 1986-08-04
DK403587A (da) 1988-02-05
EP0256999B1 (en) 1991-12-18
DK403587D0 (da) 1987-08-03
ES2039262T3 (es) 1993-09-16
JPH085786B2 (ja) 1996-01-24
US4751242A (en) 1988-06-14
CA1298197C (en) 1992-03-31
DK164641B (da) 1992-07-27
ATE70439T1 (de) 1992-01-15

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