DK164862C - Benzopyranderivater og fremgangsmaade til fremstilling heraf - Google Patents

Benzopyranderivater og fremgangsmaade til fremstilling heraf

Info

Publication number: DK164862C
Authority: DK; Denmark
Prior art keywords: group; hydrogen atom; bond; substituted; lower alkyl
Prior art date: 1986-06-04

Application number

DK281687A

Other languages

English (en)

Other versions

DK164862B (da

DK281687A (da

DK281687D0 (da

Inventor

Masayuki Kitagawa

Makoto Tanaka

Original Assignee

Daiichi Seiyaku Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-06-04

Filing date

1987-06-02

Publication date

1993-01-18

1987-06-02 Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co

1987-06-02 Publication of DK281687D0 publication Critical patent/DK281687D0/da

1987-12-05 Publication of DK281687A publication Critical patent/DK281687A/da

1992-08-31 Publication of DK164862B publication Critical patent/DK164862B/da

1993-01-18 Application granted granted Critical

1993-01-18 Publication of DK164862C publication Critical patent/DK164862C/da

Links

150000001562 benzopyrans Chemical class 0.000 title abstract 2
238000000034 method Methods 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 3
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
230000003276 anti-hypertensive effect Effects 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000006165 cyclic alkyl group Chemical group 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
230000001882 diuretic effect Effects 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000003831 tetrazolyl group Chemical group 0.000 abstract 1
125000004953 trihalomethyl group Chemical group 0.000 abstract 1
230000003424 uricosuric effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
- C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
- C07D311/38—2,3-Dihydro derivatives, e.g. isoflavanones

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Hematology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK281687A 1986-06-04 1987-06-02 Benzopyranderivater og fremgangsmaade til fremstilling heraf DK164862C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP12942086		1986-06-04
JP12942086		1986-06-04

Publications (4)

Publication Number	Publication Date
DK281687D0 DK281687D0 (da)	1987-06-02
DK281687A DK281687A (da)	1987-12-05
DK164862B DK164862B (da)	1992-08-31
DK164862C true DK164862C (da)	1993-01-18

Family

ID=15009071

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK281687A DK164862C (da)	1986-06-04	1987-06-02	Benzopyranderivater og fremgangsmaade til fremstilling heraf

Country Status (17)

Country	Link
US (1)	US4841076A (da)
EP (1)	EP0248420B1 (da)
JP (1)	JPH0681750B2 (da)
KR (1)	KR930009793B1 (da)
CN (1)	CN1020100C (da)
AT (1)	ATE67491T1 (da)
AU (1)	AU611083B2 (da)
CA (1)	CA1319694C (da)
DE (1)	DE3773053D1 (da)
DK (1)	DK164862C (da)
ES (1)	ES2044867T3 (da)
GR (1)	GR3003372T3 (da)
IE (1)	IE60203B1 (da)
NZ (1)	NZ220540A (da)
PH (1)	PH24882A (da)
YU (1)	YU46209B (da)
ZA (1)	ZA873745B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4889871A (en) *	1987-05-29	1989-12-26	G. D. Searle & Co.	Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives
AU628331B2 (en) *	1988-05-06	1992-09-17	Merck Patent Gesellschaft Mit Beschrankter Haftung	Chroman derivatives
GB8823980D0 (en) *	1988-10-13	1988-11-23	Glaxo Group Ltd	Chemical compounds
US5703075A (en) *	1988-12-21	1997-12-30	Pharmacia & Upjohn Company	Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones
EP0459983A1 (en) *	1988-12-21	1991-12-11	PHARMACIA & UPJOHN COMPANY	Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones
JPH0366669A (ja) *	1989-08-03	1991-03-22	Shionogi & Co Ltd	複素環式化合物
ATE158288T1 (de) *	1990-06-20	1997-10-15	Upjohn Co	Antiatherosklerotische und antithrombotische 1- benzopyran-4-on- und 2-amino-1,3-benzoxazin-4-on- derivate
US5204369A (en) *	1991-07-01	1993-04-20	The Endowment For Research In Human Biology	Method for the inhibition of aldh-i useful in the treatment of alcohol dependence or alcohol abuse
FR2693724B1 (fr) *	1992-07-17	1994-10-07	Lipha	Utilisation de composés benzopyraniques ou benzothiopyraniques pour l'induction de l'expression des gènes de la nodulation des bactéries du genre Rhizobium associées aux légumineuses.
EP0674530B1 (en) *	1992-12-21	2004-09-01	Mallinckrodt Inc.	Radiolabeled polyhydric phenol compounds
US5457124A (en) *	1993-12-07	1995-10-10	Hoffmann-La Roche Inc.	Carboxylic acid Leukotriene B4 antagonists
AU4315996A (en) *	1994-12-28	1996-07-19	Dainippon Pharmaceutical Co. Ltd.	Carboxylic acid derivatives, process for producing the same, and medicinal composition containing the same
IL123701A (en) *	1995-10-13	2002-03-10	Agrevo Uk Ltd	Heterocyclic fungicides and a number of new compounds
US6255497B1 (en)	1997-04-29	2001-07-03	The Endowment For Research In Human Biology, Inc.	Method for the inhibition of ALDH-I useful in the treatment of alcohol dependence or alcohol abuse
HUP9902721A2 (hu)	1997-11-25	1999-12-28	The Procter & Gamble Co.	Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület
TR200102992T2 (tr) *	1999-04-16	2004-12-21	Astrazeneca Ab	ß östrojen reseptörü ligandları.
GB0412769D0 (en)	2004-06-08	2004-07-07	Novartis Ag	Organic compounds
GB0412768D0 (en) *	2004-06-08	2004-07-07	Novartis Ag	Organic compounds
KR100930467B1 (ko) *	2007-06-07	2009-12-08	동아제약주식회사	점액분비를 촉진시키는 3',4',5-트리메톡시 플라본 유도체화합물, 그의 제조방법 및 약학적 용도
US8093253B2 (en) *	2008-03-06	2012-01-10	Hoffmann-La Roche Inc.	Leukotriene B4 inhibitors
CN103044377B (zh) *	2013-01-08	2014-12-10	中国药科大学	具有抑制黄嘌呤氧化酶和降尿酸作用的化合物以及组合物
KR101885219B1 (ko) *	2013-08-27	2018-08-14	시노켐 코포레이션	치환체 벤질옥시 그룹 함유 에테르 화합물을 포함하는 항종양제.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DD24560A (da) *
GB803372A (en) *	1955-11-02	1958-10-22	Recordati Lab Farmacologico S	Hydroxychromone derivatives and methods of preparing the same
DE1193511B (de) *	1961-03-16	1965-05-26	Cassella Farbwerke Mainkur Ag	Verfahren zur Herstellung von Derivaten des 7-Oxychromons
DE1210882B (de) *	1961-07-14	1966-02-17	Cassella Farbwerke Mainkur Ag	Verfahren zur Herstellung von Derivaten des 7-Oxychromons
BE666541A (da) *	1964-07-08
US3864362A (en) *	1970-05-27	1975-02-04	Chinoin Gyogyszer Es Vegyeszet	Iso flavones
HU162377B (da) *	1970-05-27	1973-02-28
US4644012A (en) *	1983-12-21	1987-02-17	Takeda Chemical Industries, Ltd.	Treatment for osteoporosis
DE3505611A1 (de) *	1984-11-26	1986-05-28	Merck Patent Gmbh, 6100 Darmstadt	Halogen-hydroxy-flavone
US4678787A (en) *	1985-01-30	1987-07-07	Warner-Lambert Company	4H-1-benzopyran-4-ones and their sulfur containing analogs

1987
- 1987-05-25 ZA ZA873745A patent/ZA873745B/xx unknown
- 1987-05-29 PH PH35323A patent/PH24882A/en unknown
- 1987-06-02 CA CA000538633A patent/CA1319694C/en not_active Expired - Fee Related
- 1987-06-02 DK DK281687A patent/DK164862C/da not_active IP Right Cessation
- 1987-06-02 YU YU101787A patent/YU46209B/sh unknown
- 1987-06-03 DE DE8787108047T patent/DE3773053D1/de not_active Expired - Lifetime
- 1987-06-03 KR KR1019870005613A patent/KR930009793B1/ko not_active Expired - Fee Related
- 1987-06-03 EP EP87108047A patent/EP0248420B1/en not_active Expired - Lifetime
- 1987-06-03 AT AT87108047T patent/ATE67491T1/de active
- 1987-06-03 IE IE146287A patent/IE60203B1/en not_active IP Right Cessation
- 1987-06-03 ES ES87108047T patent/ES2044867T3/es not_active Expired - Lifetime
- 1987-06-03 NZ NZ220540A patent/NZ220540A/en unknown
- 1987-06-03 JP JP62139250A patent/JPH0681750B2/ja not_active Expired - Fee Related
- 1987-06-04 US US07/058,105 patent/US4841076A/en not_active Expired - Fee Related
- 1987-06-04 AU AU73815/87A patent/AU611083B2/en not_active Ceased
- 1987-06-04 CN CN87104319A patent/CN1020100C/zh not_active Expired - Fee Related
1991
- 1991-12-18 GR GR91402056T patent/GR3003372T3/el unknown

Also Published As

Publication number	Publication date
US4841076A (en)	1989-06-20
EP0248420A3 (en)	1988-10-12
EP0248420B1 (en)	1991-09-18
CA1319694C (en)	1993-06-29
AU611083B2 (en)	1991-06-06
IE871462L (en)	1987-12-04
YU46209B (sh)	1993-05-28
CN1020100C (zh)	1993-03-17
YU101787A (en)	1988-10-31
CN87104319A (zh)	1988-05-04
JPS63107971A (ja)	1988-05-12
ZA873745B (en)	1988-10-26
NZ220540A (en)	1990-04-26
JPH0681750B2 (ja)	1994-10-19
KR880000421A (ko)	1988-03-25
PH24882A (en)	1990-12-26
IE60203B1 (en)	1994-06-15
KR930009793B1 (ko)	1993-10-11
DK164862B (da)	1992-08-31
DE3773053D1 (de)	1991-10-24
AU7381587A (en)	1987-12-10
DK281687A (da)	1987-12-05
ATE67491T1 (de)	1991-10-15
ES2044867T3 (es)	1994-01-16
DK281687D0 (da)	1987-06-02
GR3003372T3 (en)	1993-02-17
EP0248420A2 (en)	1987-12-09

Legal Events

Date	Code	Title	Description
1995-02-27	PBP	Patent lapsed

Publication	Publication Date	Title
ATE67491T1 (de)	1991-10-15	Benzopyran-derivate.
ATE404561T1 (de)	2008-08-15	Neue adeninderivate
ATE138921T1 (de)	1996-06-15	Xanthinderivate
ES2082780T3 (es)	1996-04-01	Derivados de acido bisfosfonico heterociclicos.
DK66789A (da)	1989-08-23	Bicycloheptencarboxylsyrederivater
ES2093041T3 (es)	1996-12-16	Derivados de 2-oxo-(1,8-naftiridina).
DK0408044T3 (da)	1993-06-21	Antiinflammatorisk og/eller antiallergisk præparat, der omfatter glutathionderivater
DK1010698T3 (da)	2002-07-22	Hidtil ukendte derivater af 1,2-dithiolan, fremgangsmåde til fremstiling deraf og farmaceutiske sammensætninger indeholdende dem
NO903084D0 (no)	1990-07-11	Farmasoeytisk anvendbare thiazol-derivater og fremgangsmaate for deres fremstilling.
DK517486A (da)	1987-05-01	3-imino-pyridazinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske midler der indeholder dem
NO872982D0 (no)	1987-07-16	Nye tetracykliske indolderivater.
DE69026098D1 (de)	1996-04-25	Organogermaniumderivate enthaltende Zubereitungen zur therapeutischen Verwendung
ATA262787A (de)	1990-01-15	Pharmazeutische verwendung einer 8-chlorobenzothiazepinverbindung