DK281687D0 - Benzopyranderivater - Google Patents
BenzopyranderivaterInfo
- Publication number
- DK281687D0 DK281687D0 DK281687A DK281687A DK281687D0 DK 281687 D0 DK281687 D0 DK 281687D0 DK 281687 A DK281687 A DK 281687A DK 281687 A DK281687 A DK 281687A DK 281687 D0 DK281687 D0 DK 281687D0
- Authority
- DK
- Denmark
- Prior art keywords
- group
- hydrogen atom
- bond
- substituted
- lower alkyl
- Prior art date
Links
- KYNSBQPICQTCGU-UHFFFAOYSA-N Benzopyrane Chemical compound C1=CC=C2C=CCOC2=C1 KYNSBQPICQTCGU-UHFFFAOYSA-N 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001562 benzopyrans Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000006165 cyclic alkyl group Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
- 125000004953 trihalomethyl group Chemical group 0.000 abstract 1
- 230000003424 uricosuric effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
- C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
- C07D311/38—2,3-Dihydro derivatives, e.g. isoflavanones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12942086 | 1986-06-04 | ||
| JP12942086 | 1986-06-04 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK281687D0 true DK281687D0 (da) | 1987-06-02 |
| DK281687A DK281687A (da) | 1987-12-05 |
| DK164862B DK164862B (da) | 1992-08-31 |
| DK164862C DK164862C (da) | 1993-01-18 |
Family
ID=15009071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK281687A DK164862C (da) | 1986-06-04 | 1987-06-02 | Benzopyranderivater og fremgangsmaade til fremstilling heraf |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4841076A (da) |
| EP (1) | EP0248420B1 (da) |
| JP (1) | JPH0681750B2 (da) |
| KR (1) | KR930009793B1 (da) |
| CN (1) | CN1020100C (da) |
| AT (1) | ATE67491T1 (da) |
| AU (1) | AU611083B2 (da) |
| CA (1) | CA1319694C (da) |
| DE (1) | DE3773053D1 (da) |
| DK (1) | DK164862C (da) |
| ES (1) | ES2044867T3 (da) |
| GR (1) | GR3003372T3 (da) |
| IE (1) | IE60203B1 (da) |
| NZ (1) | NZ220540A (da) |
| PH (1) | PH24882A (da) |
| YU (1) | YU46209B (da) |
| ZA (1) | ZA873745B (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4889871A (en) * | 1987-05-29 | 1989-12-26 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives |
| AU628331B2 (en) * | 1988-05-06 | 1992-09-17 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Chroman derivatives |
| GB8823980D0 (en) * | 1988-10-13 | 1988-11-23 | Glaxo Group Ltd | Chemical compounds |
| US5703075A (en) * | 1988-12-21 | 1997-12-30 | Pharmacia & Upjohn Company | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
| WO1990006921A1 (en) * | 1988-12-21 | 1990-06-28 | The Upjohn Company | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
| JPH0366669A (ja) * | 1989-08-03 | 1991-03-22 | Shionogi & Co Ltd | 複素環式化合物 |
| JPH05509302A (ja) * | 1990-06-20 | 1993-12-22 | ジ・アップジョン・カンパニー | 抗アテローム性動脈硬化性および抗血栓性1―ベンゾピラン―4―オン類および2―アミノ―1,3―ベンゾオキサジン―4―オン類 |
| US5204369A (en) * | 1991-07-01 | 1993-04-20 | The Endowment For Research In Human Biology | Method for the inhibition of aldh-i useful in the treatment of alcohol dependence or alcohol abuse |
| FR2693724B1 (fr) * | 1992-07-17 | 1994-10-07 | Lipha | Utilisation de composés benzopyraniques ou benzothiopyraniques pour l'induction de l'expression des gènes de la nodulation des bactéries du genre Rhizobium associées aux légumineuses. |
| WO1994014477A1 (en) * | 1992-12-21 | 1994-07-07 | Mallinckrodt Medical, Inc. | Polyhydric phenol compounds |
| US5457124A (en) * | 1993-12-07 | 1995-10-10 | Hoffmann-La Roche Inc. | Carboxylic acid Leukotriene B4 antagonists |
| AU4315996A (en) * | 1994-12-28 | 1996-07-19 | Dainippon Pharmaceutical Co. Ltd. | Carboxylic acid derivatives, process for producing the same, and medicinal composition containing the same |
| DK0861242T3 (da) * | 1995-10-13 | 2001-08-06 | Aventis Cropscience Uk Ltd | Hetorocycliske fungicider |
| US6255497B1 (en) | 1997-04-29 | 2001-07-03 | The Endowment For Research In Human Biology, Inc. | Method for the inhibition of ALDH-I useful in the treatment of alcohol dependence or alcohol abuse |
| HUP9902721A2 (hu) | 1997-11-25 | 1999-12-28 | The Procter & Gamble Co. | Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület |
| EE200100526A (et) * | 1999-04-16 | 2002-12-16 | Astrazeneca Ab | Östrogeeni ß-retseptori ligandid |
| GB0412768D0 (en) * | 2004-06-08 | 2004-07-07 | Novartis Ag | Organic compounds |
| GB0412769D0 (en) * | 2004-06-08 | 2004-07-07 | Novartis Ag | Organic compounds |
| KR100930467B1 (ko) * | 2007-06-07 | 2009-12-08 | 동아제약주식회사 | 점액분비를 촉진시키는 3',4',5-트리메톡시 플라본 유도체화합물, 그의 제조방법 및 약학적 용도 |
| US8093253B2 (en) * | 2008-03-06 | 2012-01-10 | Hoffmann-La Roche Inc. | Leukotriene B4 inhibitors |
| CN103044377B (zh) * | 2013-01-08 | 2014-12-10 | 中国药科大学 | 具有抑制黄嘌呤氧化酶和降尿酸作用的化合物以及组合物 |
| US9895346B2 (en) * | 2013-08-27 | 2018-02-20 | Sinochem Corporation | Applications of substituent benzyloxy group containing ether compounds for preparing antitumor drugs |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD24560A (da) * | ||||
| GB803372A (en) * | 1955-11-02 | 1958-10-22 | Recordati Lab Farmacologico S | Hydroxychromone derivatives and methods of preparing the same |
| DE1210882B (de) * | 1961-07-14 | 1966-02-17 | Cassella Farbwerke Mainkur Ag | Verfahren zur Herstellung von Derivaten des 7-Oxychromons |
| DE1193511B (de) * | 1961-03-16 | 1965-05-26 | Cassella Farbwerke Mainkur Ag | Verfahren zur Herstellung von Derivaten des 7-Oxychromons |
| BE666541A (da) * | 1964-07-08 | |||
| HU162377B (da) * | 1970-05-27 | 1973-02-28 | ||
| US3864362A (en) * | 1970-05-27 | 1975-02-04 | Chinoin Gyogyszer Es Vegyeszet | Iso flavones |
| US4644012A (en) * | 1983-12-21 | 1987-02-17 | Takeda Chemical Industries, Ltd. | Treatment for osteoporosis |
| DE3505611A1 (de) * | 1984-11-26 | 1986-05-28 | Merck Patent Gmbh, 6100 Darmstadt | Halogen-hydroxy-flavone |
| US4678787A (en) * | 1985-01-30 | 1987-07-07 | Warner-Lambert Company | 4H-1-benzopyran-4-ones and their sulfur containing analogs |
-
1987
- 1987-05-25 ZA ZA873745A patent/ZA873745B/xx unknown
- 1987-05-29 PH PH35323A patent/PH24882A/en unknown
- 1987-06-02 DK DK281687A patent/DK164862C/da not_active IP Right Cessation
- 1987-06-02 CA CA000538633A patent/CA1319694C/en not_active Expired - Fee Related
- 1987-06-02 YU YU101787A patent/YU46209B/sh unknown
- 1987-06-03 IE IE146287A patent/IE60203B1/en not_active IP Right Cessation
- 1987-06-03 JP JP62139250A patent/JPH0681750B2/ja not_active Expired - Fee Related
- 1987-06-03 EP EP87108047A patent/EP0248420B1/en not_active Expired - Lifetime
- 1987-06-03 ES ES87108047T patent/ES2044867T3/es not_active Expired - Lifetime
- 1987-06-03 DE DE8787108047T patent/DE3773053D1/de not_active Expired - Lifetime
- 1987-06-03 NZ NZ220540A patent/NZ220540A/en unknown
- 1987-06-03 KR KR1019870005613A patent/KR930009793B1/ko not_active Expired - Fee Related
- 1987-06-03 AT AT87108047T patent/ATE67491T1/de active
- 1987-06-04 CN CN87104319A patent/CN1020100C/zh not_active Expired - Fee Related
- 1987-06-04 US US07/058,105 patent/US4841076A/en not_active Expired - Fee Related
- 1987-06-04 AU AU73815/87A patent/AU611083B2/en not_active Ceased
-
1991
- 1991-12-18 GR GR91402056T patent/GR3003372T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN87104319A (zh) | 1988-05-04 |
| NZ220540A (en) | 1990-04-26 |
| ATE67491T1 (de) | 1991-10-15 |
| DK281687A (da) | 1987-12-05 |
| JPH0681750B2 (ja) | 1994-10-19 |
| PH24882A (en) | 1990-12-26 |
| YU46209B (sh) | 1993-05-28 |
| DK164862B (da) | 1992-08-31 |
| KR880000421A (ko) | 1988-03-25 |
| CA1319694C (en) | 1993-06-29 |
| EP0248420B1 (en) | 1991-09-18 |
| DK164862C (da) | 1993-01-18 |
| DE3773053D1 (de) | 1991-10-24 |
| ZA873745B (en) | 1988-10-26 |
| EP0248420A3 (en) | 1988-10-12 |
| AU611083B2 (en) | 1991-06-06 |
| IE871462L (en) | 1987-12-04 |
| YU101787A (en) | 1988-10-31 |
| JPS63107971A (ja) | 1988-05-12 |
| EP0248420A2 (en) | 1987-12-09 |
| GR3003372T3 (en) | 1993-02-17 |
| AU7381587A (en) | 1987-12-10 |
| CN1020100C (zh) | 1993-03-17 |
| US4841076A (en) | 1989-06-20 |
| IE60203B1 (en) | 1994-06-15 |
| ES2044867T3 (es) | 1994-01-16 |
| KR930009793B1 (ko) | 1993-10-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |