DK1648897T3 - N-3-3-substituerede-pyrazolo[1,5-A]pyrimidin-7YL)phenyl]-sulfonamider og sammensætninger og dermed relaterede fremgangsmåder - Google Patents

N-3-3-substituerede-pyrazolo[1,5-A]pyrimidin-7YL)phenyl]-sulfonamider og sammensætninger og dermed relaterede fremgangsmåder

Info

Publication number: DK1648897T3
Authority: DK; Denmark
Prior art keywords: pyrazolo; sulfonamides; pyrimidine; phenyl; substituted
Prior art date: 2003-07-24

Application number

DK04741223T

Other languages

English (en)

Inventor

Luis Anglada

Albert Palomer

Marta Princep

Antonio Guglietta

Original Assignee

Ferrer Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-24

Filing date

2004-07-22

Publication date

2009-04-06

2004-07-22 Application filed by Ferrer Int filed Critical Ferrer Int

2009-04-06 Application granted granted Critical

2009-04-06 Publication of DK1648897T3 publication Critical patent/DK1648897T3/da

Links

239000000203 mixture Substances 0.000 title 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
229940124530 sulfonamide Drugs 0.000 title 1
150000003456 sulfonamides Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK04741223T 2003-07-24 2004-07-22 N-3-3-substituerede-pyrazolo[1,5-A]pyrimidin-7YL)phenyl]-sulfonamider og sammensætninger og dermed relaterede fremgangsmåder DK1648897T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
ES200301746A ES2222813B1 (es)	2003-07-24	2003-07-24	N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
ES200401697A ES2245894B1 (es)	2003-07-24	2004-07-12	Mejoras en el objeto de la patente de invencion n.p200301746 que se refiere a "n-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados".
PCT/EP2004/008208 WO2005014597A1 (en)	2003-07-24	2004-07-22	N-[3-(3-SUBSTITUTED-PYRAZOLO[1,5-a]PYRIMIDIN-7-YL)PHENYL]-SULFONAMIDES, AND COMPOSITIONS, AND METHODS RELATED THERETO

Publications (1)

Publication Number	Publication Date
DK1648897T3 true DK1648897T3 (da)	2009-04-06

Family

ID=34137682

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04741223T DK1648897T3 (da)	2003-07-24	2004-07-22	N-3-3-substituerede-pyrazolo[1,5-A]pyrimidin-7YL)phenyl]-sulfonamider og sammensætninger og dermed relaterede fremgangsmåder

Country Status (29)

Country	Link
US (1)	US7947688B2 (da)
EP (1)	EP1648897B1 (da)
JP (1)	JP2006528608A (da)
KR (1)	KR100840450B1 (da)
CN (1)	CN100393721C (da)
AR (1)	AR047017A1 (da)
AT (1)	ATE417048T1 (da)
AU (1)	AU2004263278B2 (da)
BR (1)	BRPI0412826A (da)
CA (1)	CA2532437C (da)
CL (1)	CL2004001814A1 (da)
DE (1)	DE602004018320D1 (da)
DK (1)	DK1648897T3 (da)
EA (1)	EA009519B1 (da)
ES (2)	ES2222813B1 (da)
HR (1)	HRP20060009A2 (da)
IL (1)	IL173252A0 (da)
MA (1)	MA27944A1 (da)
MX (1)	MXPA06000754A (da)
NO (1)	NO20060580L (da)
NZ (1)	NZ544349A (da)
PA (1)	PA8607501A1 (da)
PE (1)	PE20050254A1 (da)
PL (1)	PL1648897T3 (da)
PT (1)	PT1648897E (da)
TW (1)	TWI340140B (da)
UA (1)	UA81959C2 (da)
UY (1)	UY28440A1 (da)
WO (1)	WO2005014597A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2006084835A1 (en) *	2005-02-10	2006-08-17	Ferrer Internacional, S. A.	N-(3-(imidazo [1,5-a]pyrimidin-4-yl)phenyl]-sulfonamides and n-[3-(imidazo[1,5-a]pyrimidin-4-yl)-phenyl]-carboxamides and their use as gabaa receptor modulators
EP1736475A1 (en)	2005-06-21	2006-12-27	Ferrer Internacional, S.A.	Halogenated pyrazolo[1,5-a]pyrimidines, processes, uses, compositions and intermediates
US20070219186A1 (en) *	2006-03-17	2007-09-20	Wyeth	Pyrazolo[1,5-A]pyrimidine derivatives and methods of use thereof
EP1845098A1 (en) *	2006-03-29	2007-10-17	Ferrer Internacional, S.A.	Imidazo[1,2-b]pyridazines, their processes of preparation and their use as GABA receptor ligands
EP1884516A1 (en)	2006-08-04	2008-02-06	Ferrer Internacional, S.A.	Pyrazolo[1,5-a]pyrimidines, processes, uses and compositions
EP1956021A1 (en) *	2006-10-11	2008-08-13	Ferrer Internacional, S.A.	Process for the manufacture of a crystalline pyrazolo[1,5-a]pyrimidine compound
EP1921079A1 (en) *	2006-11-08	2008-05-14	Ferrer Internacional, S.A.	Amorphous form of N-{2-Fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a] pyrimidin-7-yl]-phenyl}-N-methyl-acetamide
PT2387557E (pt) *	2009-01-13	2013-09-11	Interquim Sa	Processo para a preparação de n-[5-(3-dimetilaminoacriloil)- 2-fluorofenil]-n-metil-acetamida
WO2013039985A2 (en) *	2011-09-12	2013-03-21	The Johns Hopkins University	Serine protease inhibitors
CN102807569B (zh) *	2012-08-21	2015-02-25	四川大学	一种镇静催眠的化合物及其制备方法和用途
KR102148681B1 (ko) *	2013-02-21	2020-08-27	칼리토르 사이언시즈, 엘엘씨	Pi3 키나제 모듈레이터로서의 헤테로방향족 화합물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE792533A (fr) *	1971-12-09	1973-06-08	Int Chem & Nuclear Corp	Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation
US4626538A (en) *	1983-06-23	1986-12-02	American Cyanamid Company	[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines
US4654347A (en) *	1983-06-23	1987-03-31	American Cyanamid Company	Aryl and heteroaryl[[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]methanones
NZ208554A (en) *	1983-06-23	1987-06-30	American Cyanamid Co	(aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions
DE3689294T2 (de) *	1985-05-13	1994-06-09	American Cyanamid Co	[7-(3-Disubstituierte Amino)phenyl]pyrazolo[1,5-a]-pyrimidine.
EP0264773A1 (en) *	1986-10-16	1988-04-27	American Cyanamid Company	4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines
DE4333705C2 (de) *	1993-10-02	2003-10-30	Guenter Ege	Arylmethylsubstituierte Pyrazolo-azine, insbesondere 3-Arylmethylpyrazolo[1,5-a]pyrimidine und Verfahren zur Herstellung von 8-Arylmethyl-pyrazolo[5,1-c][1,2,4]triazinen
US5538977A (en) *	1995-03-17	1996-07-23	American Cyanamid Company	3-Substituted-7-[3-(imidazol-1-yl)phenyl]-pyrazolo[1,5-a]pyrimidines
DE60014339T8 (de) *	1999-04-02	2006-04-27	Neurogen Corp., Branford	Aryl- und heteroaryl-kondensierte aminoalkyl-imidazol-derivate: selektive modulatoren der gabaa-rezeptoren
US6399621B1 (en) *	1999-08-10	2002-06-04	American Cyanamid Company	N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto

2003
- 2003-07-24 ES ES200301746A patent/ES2222813B1/es not_active Expired - Fee Related
2004
- 2004-07-12 ES ES200401697A patent/ES2245894B1/es not_active Expired - Fee Related
- 2004-07-15 TW TW093121113A patent/TWI340140B/zh not_active IP Right Cessation
- 2004-07-20 CL CL200401814A patent/CL2004001814A1/es unknown
- 2004-07-20 PA PA20048607501A patent/PA8607501A1/es unknown
- 2004-07-22 AU AU2004263278A patent/AU2004263278B2/en not_active Ceased
- 2004-07-22 CA CA2532437A patent/CA2532437C/en not_active Expired - Fee Related
- 2004-07-22 KR KR1020067001267A patent/KR100840450B1/ko not_active Expired - Fee Related
- 2004-07-22 NZ NZ544349A patent/NZ544349A/en not_active IP Right Cessation
- 2004-07-22 CN CNB2004800214537A patent/CN100393721C/zh not_active Expired - Fee Related
- 2004-07-22 US US10/562,559 patent/US7947688B2/en not_active Expired - Fee Related
- 2004-07-22 MX MXPA06000754A patent/MXPA06000754A/es active IP Right Grant
- 2004-07-22 EA EA200600316A patent/EA009519B1/ru not_active IP Right Cessation
- 2004-07-22 JP JP2006520796A patent/JP2006528608A/ja active Pending
- 2004-07-22 UA UAA200600630A patent/UA81959C2/uk unknown
- 2004-07-22 EP EP04741223A patent/EP1648897B1/en not_active Expired - Lifetime
- 2004-07-22 AT AT04741223T patent/ATE417048T1/de active
- 2004-07-22 BR BRPI0412826-5A patent/BRPI0412826A/pt not_active IP Right Cessation
- 2004-07-22 WO PCT/EP2004/008208 patent/WO2005014597A1/en not_active Ceased
- 2004-07-22 HR HR20060009A patent/HRP20060009A2/xx not_active Application Discontinuation
- 2004-07-22 PT PT04741223T patent/PT1648897E/pt unknown
- 2004-07-22 DE DE602004018320T patent/DE602004018320D1/de not_active Expired - Lifetime
- 2004-07-22 DK DK04741223T patent/DK1648897T3/da active
- 2004-07-22 PL PL04741223T patent/PL1648897T3/pl unknown
- 2004-07-23 AR ARP040102619A patent/AR047017A1/es unknown
- 2004-07-23 PE PE2004000710A patent/PE20050254A1/es not_active Application Discontinuation
- 2004-07-26 UY UY28440A patent/UY28440A1/es not_active Application Discontinuation
2006
- 2006-01-19 IL IL173252A patent/IL173252A0/en unknown
- 2006-02-03 NO NO20060580A patent/NO20060580L/no not_active Application Discontinuation
- 2006-02-13 MA MA28797A patent/MA27944A1/fr unknown

Also Published As

Publication number	Publication date
ES2222813B1 (es)	2005-12-16
PL1648897T3 (pl)	2009-07-31
JP2006528608A (ja)	2006-12-21
AU2004263278A1 (en)	2005-02-17
KR20060030908A (ko)	2006-04-11
CA2532437A1 (en)	2005-02-17
EP1648897A1 (en)	2006-04-26
HK1083844A1 (en)	2006-07-14
EA009519B1 (ru)	2008-02-28
UA81959C2 (en)	2008-02-25
PT1648897E (pt)	2009-03-17
MA27944A1 (fr)	2006-06-01
ES2222813A1 (es)	2005-02-01
US7947688B2 (en)	2011-05-24
HRP20060009A2 (en)	2006-08-31
TW200510422A (en)	2005-03-16
KR100840450B1 (ko)	2008-06-20
ATE417048T1 (de)	2008-12-15
IL173252A0 (en)	2006-06-11
ES2245894A1 (es)	2006-01-16
ES2245894B1 (es)	2006-12-01
EA200600316A1 (ru)	2006-06-30
BRPI0412826A (pt)	2006-09-26
NZ544349A (en)	2009-05-31
AR047017A1 (es)	2006-01-04
EP1648897B1 (en)	2008-12-10
PE20050254A1 (es)	2005-04-11
US20060270690A1 (en)	2006-11-30
PA8607501A1 (es)	2005-09-28
TWI340140B (en)	2011-04-11
AU2004263278B2 (en)	2009-03-12
NO20060580L (no)	2006-02-03
CL2004001814A1 (es)	2005-06-03
CN1829719A (zh)	2006-09-06
CA2532437C (en)	2010-01-26
MXPA06000754A (es)	2006-03-30
UY28440A1 (es)	2004-11-08
WO2005014597A1 (en)	2005-02-17
CN100393721C (zh)	2008-06-11
DE602004018320D1 (de)	2009-01-22

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FR16C1000I2 (fr)	2017-02-03	Compositions comprenant des polypeptides
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DE60200746D1 (de)	2004-08-19	Kautschukzusammensetzung
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NO20055568D0 (no)	2005-11-24	Substituerte 1,4-diazepiner og anvendelser derav
DE60318511D1 (de)	2008-02-21	Gleitelement
DE60308579D1 (de)	2006-11-09	Gleitelement
EP1703908A4 (en)	2009-07-08	ARYLSULFONAMIDE COMPOUNDS AND RELATED APPLICATIONS
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DE10290365T1 (de)	2003-12-18	Gummizusammensetzung
DE60212442D1 (de)	2006-07-27	Kautschukzusammensetzung
ATE417648T1 (de)	2009-01-15	Stifte zusammensetzungen
DE602004024982D1 (de)	2010-02-25	Nahrungsmittel enthaltend sättigungsmittel
DE60129749D1 (de)	2007-09-13	Kautschukzusammensetzung
ATE369745T1 (de)	2007-09-15	Herbizide zusammensetzung
FI20031004A0 (fi)	2003-07-03	Uusi syötävä koostumus
DK1663191T3 (da)	2010-04-26	Sammensætning omfattende rosiglitazon og metformin
BR0310113B1 (pt)	2013-10-29	Composições pesticidas
DE60236587D1 (de)	2010-07-15	Latexzusammensetzung
PT1353554E (pt)	2004-11-30	Misturas fungicidas
DK1680134T3 (da)	2014-07-14	Sammensætninger og anvendelser deraf
DE60239055D1 (de)	2011-03-10	Verbesserungen in der lederherstellung
ITTO20040104A1 (it)	2004-05-24	Composizione pesticida