DK165453C - Fremgangsmaade til fremstilling af 2'-desoxyadenosinforbindelser - Google Patents

Fremgangsmaade til fremstilling af 2'-desoxyadenosinforbindelser

Info

Publication number
DK165453C
DK165453C DK357585A DK357585A DK165453C DK 165453 C DK165453 C DK 165453C DK 357585 A DK357585 A DK 357585A DK 357585 A DK357585 A DK 357585A DK 165453 C DK165453 C DK 165453C
Authority
DK
Denmark
Prior art keywords
desoxyadenos
preparing
compounds
deoxyadenosine
dichloropurine
Prior art date
Application number
DK357585A
Other languages
Danish (da)
English (en)
Other versions
DK357585A (da
DK165453B (da
DK357585D0 (da
Inventor
Roland Kenith Robins
Ganapathi Ramakrishna Revankar
Original Assignee
Univ Brigham Young
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Brigham Young filed Critical Univ Brigham Young
Publication of DK357585D0 publication Critical patent/DK357585D0/da
Publication of DK357585A publication Critical patent/DK357585A/da
Publication of DK165453B publication Critical patent/DK165453B/da
Application granted granted Critical
Publication of DK165453C publication Critical patent/DK165453C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK357585A 1984-08-06 1985-08-06 Fremgangsmaade til fremstilling af 2'-desoxyadenosinforbindelser DK165453C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63819284A 1984-08-06 1984-08-06
US63819284 1984-08-06

Publications (4)

Publication Number Publication Date
DK357585D0 DK357585D0 (da) 1985-08-06
DK357585A DK357585A (da) 1986-02-07
DK165453B DK165453B (da) 1992-11-30
DK165453C true DK165453C (da) 1993-04-13

Family

ID=24559020

Family Applications (1)

Application Number Title Priority Date Filing Date
DK357585A DK165453C (da) 1984-08-06 1985-08-06 Fremgangsmaade til fremstilling af 2'-desoxyadenosinforbindelser

Country Status (9)

Country Link
EP (1) EP0173059B1 (fr)
JP (2) JPS61106594A (fr)
AT (1) ATE48278T1 (fr)
AU (1) AU572673B2 (fr)
CA (1) CA1269659A (fr)
DE (1) DE3574472D1 (fr)
DK (1) DK165453C (fr)
ES (1) ES8606383A1 (fr)
ZA (1) ZA855696B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0217199A (ja) * 1988-07-05 1990-01-22 Japan Tobacco Inc ２’−デオキシ−β−アデノシンの製造方法
JPH02160799A (ja) * 1988-12-13 1990-06-20 Yuki Gosei Kogyo Co Ltd ２′−デオキシ−β−アデノシンの製造法
US5208327A (en) * 1991-12-18 1993-05-04 Ortho Pharmaceutical Corporation Intermediates useful in a synthesis of 2-chloro-2'-deoxyadenosine
AU2003275267A1 (en) * 2002-09-25 2004-04-19 Brigham Young University, Technology Transfer Office Method for the preparation of 2-halo-2'-deoxyadenosine compounds from 2'-deoxyguanosine
LT3332789T (lt) 2004-12-22 2022-07-25 Merck Serono Sa Kladribino režimas, skirtas išsėtinės sklerozės gydymui
US9925151B2 (en) 2006-05-24 2018-03-27 Merck Serono Sa Cladribine regimen for treating multiple sclerosis
PL1932918T3 (pl) 2006-12-15 2010-03-31 Explora Laboratories Sa Sposób otrzymywania kladrybiny
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
WO2010075517A2 (fr) 2008-12-23 2010-07-01 Pharmasset, Inc. Analogues de nucléoside
WO2010075554A1 (fr) 2008-12-23 2010-07-01 Pharmasset, Inc. Synthèse de nucléosides de type purine
AR074897A1 (es) 2008-12-23 2011-02-23 Pharmasset Inc Fosforamidatos de nucleosidos
TWI399381B (zh) 2009-08-18 2013-06-21 Scinopharm Taiwan Ltd 克拉屈濱（ｃｌａｄｒｉｂｉｎｅ）的製備方法
EP2343074A1 (fr) 2009-12-23 2011-07-13 Merck Serono S.A. Utilisation d'analogues de la purine pour traiter des maladies des voies respiratoires
WO2011113476A2 (fr) 2010-03-16 2011-09-22 Cilag Ag Procédé de production de composés de 2'-désoxyadénosine
RS54368B1 (sr) 2010-03-31 2016-04-28 Gilead Pharmasset Llc Kristalni (s)-izopropil 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-diokso-3,4-dihidropirimidin-1-(2h)-il)-4-fluoro-3-hidroksi-4-metiltetrahidrofuran-2-il)metoksi)(fenoksi)fosforil)amino)propanoat
GB201401465D0 (en) 2014-01-29 2014-03-12 Roach Arthur H Use of cladribine for treating autoimmune inflammatory disease
EP2993177A1 (fr) 2014-09-05 2016-03-09 Technische Universität Berlin Procédé de préparation chimio-enzymatique de purines nucléosides et leurs analogues aza- et deaza-
GB2564717A (en) 2017-07-21 2019-01-23 Chord Therapeutics S A R L Use of cladribine for treating autoimmune neuromuscular disease
TW202537627A (zh) 2017-11-24 2025-10-01 德商馬克專利公司 用於治療進展型多發性硬化症之克拉屈濱(cladribine)療程
US20240226284A1 (en) 2020-09-10 2024-07-11 Merck Patent Gmbh Novel treatment regimen for the treatment of autoimmune disorders
GB2601786A (en) 2020-12-10 2022-06-15 Chord Therapeutics S A R L Use of cladribine for treating immune brain disease
WO2022184867A1 (fr) 2021-03-03 2022-09-09 Merck Patent Gmbh Procédés de traitement améliorés utilisant des dmd pour le traitement de maladies auto-immunes, et biomarqueur pour prédire et/ou optimiser lesdits procédés de traitement
DE102023123718A1 (de) 2023-09-04 2025-03-06 CHIRACON Pharma GmbH Verfahren zur Herstellung von Nukleosiden

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3225029A (en) * 1962-03-08 1965-12-21 Yamaoka Naotaka Process for the preparation of nucleosides and products obtained thereby
US3225008A (en) * 1962-05-21 1965-12-21 Scott Paper Co Itaconic esters of 1,2 alkane carbonates, polymers, and copolymers thereof
DE1795357A1 (de) * 1968-09-18 1972-01-05 Schering Ag 2-Thio-pyrimidin-nucleoside
EP0184365B1 (fr) * 1984-12-04 1993-08-04 Eli Lilly And Company Traitement de tumeurs chez les mammifères

Also Published As

Publication number Publication date
EP0173059A2 (fr) 1986-03-05
ZA855696B (en) 1986-04-30
JPS61106594A (ja) 1986-05-24
ES545888A0 (es) 1986-04-01
DK357585A (da) 1986-02-07
DK165453B (da) 1992-11-30
JPH0256497A (ja) 1990-02-26
ATE48278T1 (de) 1989-12-15
CA1269659A (fr) 1990-05-29
AU4513885A (en) 1986-02-13
DK357585D0 (da) 1985-08-06
EP0173059A3 (en) 1987-04-29
DE3574472D1 (de) 1990-01-04
ES8606383A1 (es) 1986-04-01
JPH02359B2 (fr) 1990-01-08
EP0173059B1 (fr) 1989-11-29
AU572673B2 (en) 1988-05-12

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