DK170776B1 - N-[[[1-(Naphth-2-ylmethyl)-4-piperidinyl]-amino]-carbonyl]-pyridincarboxamid, og salte deraf samt farmaceutisk præparat indeholdende dem. - Google Patents

N-[[[1-(Naphth-2-ylmethyl)-4-piperidinyl]-amino]-carbonyl]-pyridincarboxamid, og salte deraf samt farmaceutisk præparat indeholdende dem. Download PDF

Info

Publication number: DK170776B1
Authority: DK; Denmark
Prior art keywords: amino; carbonyl; piperidinyl; pyridinecarboxamide; compound
Prior art date: 1985-11-15

Application number

DK546386A

Other languages

Danish (da)

English (en)

Other versions

DK546386A (da

DK546386D0 (da

Inventor

John Leheup Archibald

Terence James Ward

Original Assignee

Wyeth John & Brother Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-11-15

Filing date

1986-11-14

Publication date

1996-01-15

1986-11-14 Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd

1986-11-14 Publication of DK546386D0 publication Critical patent/DK546386D0/da

1987-05-16 Publication of DK546386A publication Critical patent/DK546386A/da

1996-01-15 Application granted granted Critical

1996-01-15 Publication of DK170776B1 publication Critical patent/DK170776B1/da

Links

150000003839 salts Chemical class 0.000 title claims abstract description 16
AZBZTJCNHYWUAF-UHFFFAOYSA-N n-[[1-(naphthalen-2-ylmethyl)piperidin-4-yl]carbamoyl]pyridine-2-carboxamide Chemical compound C1CN(CC=2C=C3C=CC=CC3=CC=2)CCC1NC(=O)NC(=O)C1=CC=CC=N1 AZBZTJCNHYWUAF-UHFFFAOYSA-N 0.000 title claims description 3
239000000825 pharmaceutical preparation Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 claims abstract description 52
229910052739 hydrogen Inorganic materials 0.000 claims abstract description 8
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125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract description 4
125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 claims abstract description 3
125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 claims abstract description 3
239000000203 mixture Substances 0.000 claims description 12
239000002253 acid Substances 0.000 claims description 8
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YYWKMPCKXDNMTJ-UHFFFAOYSA-N n-[[1-[(6-fluoronaphthalen-2-yl)methyl]piperidin-4-yl]carbamoyl]pyridine-3-carboxamide Chemical group C1=CC2=CC(F)=CC=C2C=C1CN(CC1)CCC1NC(=O)NC(=O)C1=CC=CN=C1 YYWKMPCKXDNMTJ-UHFFFAOYSA-N 0.000 claims description 5
UGZGSRSVQUEJDA-UHFFFAOYSA-N n-[[1-[(6-fluoronaphthalen-2-yl)methyl]piperidin-4-yl]carbamoyl]pyridine-4-carboxamide Chemical group C1=CC2=CC(F)=CC=C2C=C1CN(CC1)CCC1NC(=O)NC(=O)C1=CC=NC=C1 UGZGSRSVQUEJDA-UHFFFAOYSA-N 0.000 claims description 4
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238000009472 formulation Methods 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
239000007903 gelatin capsule Substances 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
238000007429 general method Methods 0.000 description 1
150000002334 glycols Chemical class 0.000 description 1
239000008187 granular material Substances 0.000 description 1
150000004820 halides Chemical class 0.000 description 1
125000001072 heteroaryl group Chemical group 0.000 description 1
125000000623 heterocyclic group Chemical group 0.000 description 1
XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
208000013403 hyperactivity Diseases 0.000 description 1
238000000338 in vitro Methods 0.000 description 1
238000001727 in vivo Methods 0.000 description 1
239000003112 inhibitor Substances 0.000 description 1
239000007924 injection Substances 0.000 description 1
238000002347 injection Methods 0.000 description 1
238000007918 intramuscular administration Methods 0.000 description 1
239000011630 iodine Substances 0.000 description 1
229910052740 iodine Inorganic materials 0.000 description 1
INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 description 1
239000003456 ion exchange resin Substances 0.000 description 1
229920003303 ion-exchange polymer Polymers 0.000 description 1
239000008101 lactose Substances 0.000 description 1
239000012669 liquid formulation Substances 0.000 description 1
235000019359 magnesium stearate Nutrition 0.000 description 1
125000005905 mesyloxy group Chemical group 0.000 description 1
229940098779 methanesulfonic acid Drugs 0.000 description 1
229920000609 methyl cellulose Polymers 0.000 description 1
239000001923 methylcellulose Substances 0.000 description 1
235000010981 methylcellulose Nutrition 0.000 description 1
PCWSITVCWKDOIY-UHFFFAOYSA-N n-(pyridin-4-ylcarbamoyl)pyridine-3-carboxamide Chemical compound C=1C=NC=CC=1NC(=O)NC(=O)C1=CC=CN=C1 PCWSITVCWKDOIY-UHFFFAOYSA-N 0.000 description 1
125000001624 naphthyl group Chemical group 0.000 description 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
LDCYZAJDBXYCGN-UHFFFAOYSA-N oxitriptan Natural products C1=C(O)C=C2C(CC(N)C(O)=O)=CNC2=C1 LDCYZAJDBXYCGN-UHFFFAOYSA-N 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
239000012057 packaged powder Substances 0.000 description 1
238000004806 packaging method and process Methods 0.000 description 1
230000002093 peripheral effect Effects 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
230000000144 pharmacologic effect Effects 0.000 description 1
229910052698 phosphorus Inorganic materials 0.000 description 1
239000011574 phosphorus Substances 0.000 description 1
235000014786 phosphorus Nutrition 0.000 description 1
IBBMAWULFFBRKK-UHFFFAOYSA-N picolinamide Chemical class NC(=O)C1=CC=CC=N1 IBBMAWULFFBRKK-UHFFFAOYSA-N 0.000 description 1
125000004482 piperidin-4-yl group Chemical group N1CCC(CC1)* 0.000 description 1
125000003386 piperidinyl group Chemical group 0.000 description 1
229910052697 platinum Inorganic materials 0.000 description 1
229920006316 polyvinylpyrrolidine Polymers 0.000 description 1
230000003389 potentiating effect Effects 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
108090000765 processed proteins & peptides Proteins 0.000 description 1
ATBIAJXSKNPHEI-UHFFFAOYSA-N pyridine-3-carbonyl chloride Chemical compound ClC(=O)C1=CC=CN=C1 ATBIAJXSKNPHEI-UHFFFAOYSA-N 0.000 description 1
FSWHDPPHBYXOHR-UHFFFAOYSA-N pyridine-3-carbonyl isocyanate Chemical compound O=C=NC(=O)C1=CC=CN=C1 FSWHDPPHBYXOHR-UHFFFAOYSA-N 0.000 description 1
GWXFVEAYSPPGJH-UHFFFAOYSA-N pyridine-4-carbonyl isocyanate Chemical compound O=C=NC(=O)C1=CC=NC=C1 GWXFVEAYSPPGJH-UHFFFAOYSA-N 0.000 description 1
125000004076 pyridyl group Chemical group 0.000 description 1
238000005956 quaternization reaction Methods 0.000 description 1
238000003345 scintillation counting Methods 0.000 description 1
230000013275 serotonin uptake Effects 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
235000015424 sodium Nutrition 0.000 description 1
229910000033 sodium borohydride Inorganic materials 0.000 description 1
239000012279 sodium borohydride Substances 0.000 description 1
229910000029 sodium carbonate Inorganic materials 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
238000010561 standard procedure Methods 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
125000003107 substituted aryl group Chemical group 0.000 description 1
239000000758 substrate Substances 0.000 description 1
150000003890 succinate salts Chemical class 0.000 description 1
KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
239000001384 succinic acid Substances 0.000 description 1
235000000346 sugar Nutrition 0.000 description 1
150000005846 sugar alcohols Polymers 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
239000011593 sulfur Substances 0.000 description 1
239000000829 suppository Substances 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
239000006188 syrup Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000000454 talc Substances 0.000 description 1
229910052623 talc Inorganic materials 0.000 description 1
235000012222 talc Nutrition 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
239000002562 thickening agent Substances 0.000 description 1
125000005424 tosyloxy group Chemical group S(=O)(=O)(C1=CC=C(C)C=C1)O* 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
229910052722 tritium Inorganic materials 0.000 description 1
239000000052 vinegar Substances 0.000 description 1
235000021419 vinegar Nutrition 0.000 description 1
239000001993 wax Substances 0.000 description 1
235000014101 wine Nutrition 0.000 description 1
239000008096 xylene Substances 0.000 description 1
229910052727 yttrium Inorganic materials 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/98—Nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Veterinary Medicine (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Separation Using Semi-Permeable Membranes (AREA)
Detergent Compositions (AREA)
Air Bags (AREA)

DK546386A 1985-11-15 1986-11-14 N-[[[1-(Naphth-2-ylmethyl)-4-piperidinyl]-amino]-carbonyl]-pyridincarboxamid, og salte deraf samt farmaceutisk præparat indeholdende dem. DK170776B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB858528235A GB8528235D0 (en)	1985-11-15	1985-11-15	Heterocyclic compounds
GB8528235		1985-11-15

Publications (3)

Publication Number	Publication Date
DK546386D0 DK546386D0 (da)	1986-11-14
DK546386A DK546386A (da)	1987-05-16
DK170776B1 true DK170776B1 (da)	1996-01-15

Family

ID=10588307

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK546386A DK170776B1 (da)	1985-11-15	1986-11-14	N-[[[1-(Naphth-2-ylmethyl)-4-piperidinyl]-amino]-carbonyl]-pyridincarboxamid, og salte deraf samt farmaceutisk præparat indeholdende dem.

Country Status (18)

Country	Link
EP (1)	EP0228795B1 (fr)
JP (1)	JPH0723371B2 (fr)
KR (1)	KR940008303B1 (fr)
AT (1)	ATE60770T1 (fr)
AU (1)	AU585087B2 (fr)
CA (1)	CA1276150C (fr)
DE (1)	DE3677486D1 (fr)
DK (1)	DK170776B1 (fr)
ES (1)	ES2031823T3 (fr)
FI (1)	FI85699C (fr)
GB (2)	GB8528235D0 (fr)
GR (1)	GR3001483T3 (fr)
HU (1)	HU197739B (fr)
IE (1)	IE59007B1 (fr)
IL (1)	IL80639A (fr)
PH (1)	PH22436A (fr)
PT (1)	PT83715B (fr)
ZA (1)	ZA868557B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9508438D0 (en) *	1995-04-26	1995-06-14	Wyeth John & Brother Ltd	Medical treatment

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1573066A (en) *	1977-09-08	1980-08-13	Wyeth John & Brother Ltd	Piperidylureas and thioreas
ES8100015A1 (es) *	1978-07-18	1980-04-01	Hoechst Ag	Procedimiento para la preparacion de nuevos derivados de 2-(4-aminopiperidino)-3,4-dihidroquinoleina.
GB2034305B (en) *	1978-10-24	1982-12-22	Wyeth John & Brother Ltd	Preparation of piperidine derivatives
PL135545B1 (en) *	1980-03-01	1985-11-30	Wyeth John & Brother Ltd	Process for preparing novel derivatives of piperidine
GB2108489B (en) *	1980-03-01	1984-06-06	Wyeth John & Brother Ltd	Pharmaceutical composition comprising piperidine derivatives
GB2073176B (en) *	1980-03-01	1984-01-18	Wyeth John & Brother Ltd	Piperidine derivatives
GB2106108B (en) *	1981-09-10	1985-05-01	Wyeth John & Brother Ltd	Piperidine derivatives

1985
- 1985-11-15 GB GB858528235A patent/GB8528235D0/en active Pending
1986
- 1986-11-11 PT PT83715A patent/PT83715B/pt not_active IP Right Cessation
- 1986-11-11 ZA ZA868557A patent/ZA868557B/xx unknown
- 1986-11-12 CA CA000522789A patent/CA1276150C/fr not_active Expired - Fee Related
- 1986-11-12 AU AU65045/86A patent/AU585087B2/en not_active Ceased
- 1986-11-13 PH PH34478A patent/PH22436A/en unknown
- 1986-11-13 JP JP61270812A patent/JPH0723371B2/ja not_active Expired - Lifetime
- 1986-11-14 AT AT86308899T patent/ATE60770T1/de not_active IP Right Cessation
- 1986-11-14 HU HU864708A patent/HU197739B/hu not_active IP Right Cessation
- 1986-11-14 DK DK546386A patent/DK170776B1/da active
- 1986-11-14 DE DE8686308899T patent/DE3677486D1/de not_active Expired - Fee Related
- 1986-11-14 GB GB8627301A patent/GB2182934B/en not_active Expired
- 1986-11-14 IE IE301586A patent/IE59007B1/en not_active IP Right Cessation
- 1986-11-14 IL IL80639A patent/IL80639A/xx not_active IP Right Cessation
- 1986-11-14 FI FI864641A patent/FI85699C/fi not_active IP Right Cessation
- 1986-11-14 ES ES198686308899T patent/ES2031823T3/es not_active Expired - Lifetime
- 1986-11-14 KR KR1019860009618A patent/KR940008303B1/ko not_active Expired - Fee Related
- 1986-11-14 EP EP86308899A patent/EP0228795B1/fr not_active Expired - Lifetime
1991
- 1991-02-19 GR GR91400200T patent/GR3001483T3/el unknown

Also Published As

Publication number	Publication date
AU6504586A (en)	1987-05-21
JPH0723371B2 (ja)	1995-03-15
DK546386A (da)	1987-05-16
GB2182934A (en)	1987-05-28
HU197739B (en)	1989-05-29
HUT43842A (en)	1987-12-28
FI864641A0 (fi)	1986-11-14
IL80639A0 (en)	1987-02-27
AU585087B2 (en)	1989-06-08
KR870004958A (ko)	1987-06-02
FI85699C (fi)	1992-05-25
CA1276150C (fr)	1990-11-13
FI85699B (fi)	1992-02-14
EP0228795A1 (fr)	1987-07-15
ES2031823T3 (es)	1993-01-01
GR3001483T3 (en)	1992-10-08
IL80639A (en)	1990-07-12
ATE60770T1 (de)	1991-02-15
GB2182934B (en)	1989-09-27
PH22436A (en)	1988-09-12
IE59007B1 (en)	1993-12-15
PT83715B (pt)	1989-06-30
GB8528235D0 (en)	1985-12-18
EP0228795B1 (fr)	1991-02-06
DK546386D0 (da)	1986-11-14
FI864641L (fi)	1987-05-16
IE863015L (en)	1987-05-15
JPS62135471A (ja)	1987-06-18
ZA868557B (en)	1988-06-29
DE3677486D1 (de)	1991-03-14
KR940008303B1 (ko)	1994-09-12
GB8627301D0 (en)	1986-12-17
PT83715A (en)	1986-12-01

Publication	Publication Date	Title
US4426387A (en)	1984-01-17	Piperid-4-yl ureas and thio ureas used as anti-depressant agents
NO158419B (no)	1988-05-30	Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,2-diaminocyklobuten-3,4-dioner.
NO144262B (no)	1981-04-21	Analogifremgangsmaate ved fremstilling av terapeutisk virksomme n-substituerte benzamidderivater
DK162888B (da)	1991-12-23	Ethylendiaminmonoamid-derivater og laegemidler indeholdende disse
JPS6053014B2 (ja)	1985-11-22	薬理作用を有するピリジン誘導体
AU747815B2 (en)	2002-05-23	Cyclic amide compounds
NO322432B1 (no)	2006-10-02	Nye forbindelser, deres anvendelse og farmasoytiske sammensetninger som omfatter de nye forbindelsene
DK165919B (da)	1993-02-08	N-substituerede 3-piperidin- eller 3-pyridincarboxylsyrederivater, fremgangsmaade til fremstilling heraf og farmaceutiske praeparater indeholdende forbindelserne
DK170643B1 (da)	1995-11-20	N-(((1-(Naphthyl- eller quinolyl-methyl)-4-piperidinyl)-amino)-carbonyl)-quinolincarboxamider samt salte heraf og farmaceutisk præparat indeholdende dem
CZ270193A3 (en)	1994-08-17	Novel amidoalkyl- and imidoalkyl piperazines
SK281387B6 (sk)	2001-03-12	Deriváty kyseliny hydroxímovej, farmaceutický prostriedok, ktorý ich obsahuje, spôsob ich prípravy a medziprodukty na ich prípravu
US4514408A (en)	1985-04-30	N-substituted nicotinamide 1-oxide as histamine H2 receptor blockers
US4806552A (en)	1989-02-21	Pyridyl- and/or pyridoyl-(piperid-4-yl) ureas and analogues thereof
EP0228795B1 (fr)	1991-02-06	Dérivés de la pipéridine ayant des propriétés psychotropiques
US5057524A (en)	1991-10-15	4-[diaryl)hydroxymethyl]-1-piperidinealkylcarboxylic acids, salts and esters useful in the treatment of allergic disorders
US2846438A (en)	1958-08-05	Nu-(beta-diethylaminoethyl) isonicotinamide
US4218456A (en)	1980-08-19	1-(4-Fluorophenyl)-4-(1,2,3,6-tetrahydro-4-phenoxy-1-pyridinyl)-butanones
US2556566A (en)	1951-06-12	Method for preparing n-pyridyl-n-thenyl alkylene diamines
Vadodaria et al.	1969	Synthesis and central nervous system depressant activity of new piperazine derivatives and related compounds. II
DK161322B (da)	1991-06-24	Analogifremgangsmaade til fremstilling af n-((4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylen)azaspiroalkandioner samt mellemprodukt til brug ved fremgangsmaaden
CS234043B2 (cs)	1985-03-14	Způsob Výroby derivátů piperidinu
CS234048B2 (cs)	1985-03-14	Způsob výroby derivátů piperidinu