DK1727620T3 - C1 symmetriske biphosphinlegander og deres anvendelse i asymmetrisk syntese af pregabilin - Google Patents
C1 symmetriske biphosphinlegander og deres anvendelse i asymmetrisk syntese af pregabilinInfo
- Publication number
- DK1727620T3 DK1727620T3 DK05708733T DK05708733T DK1727620T3 DK 1727620 T3 DK1727620 T3 DK 1727620T3 DK 05708733 T DK05708733 T DK 05708733T DK 05708733 T DK05708733 T DK 05708733T DK 1727620 T3 DK1727620 T3 DK 1727620T3
- Authority
- DK
- Denmark
- Prior art keywords
- pregabiline
- symmetric
- asymmetric synthesis
- biphosphine ligands
- biphosphine
- Prior art date
Links
- 238000011914 asymmetric synthesis Methods 0.000 title 1
- VURFVHCLMJOLKN-UHFFFAOYSA-N diphosphane Chemical compound PP VURFVHCLMJOLKN-UHFFFAOYSA-N 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2282—Unsaturated compounds used as ligands
- B01J31/2295—Cyclic compounds, e.g. cyclopentadienyls
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5027—Polyphosphines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5045—Complexes or chelates of phosphines with metallic compounds or metals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/53—Organo-phosphine oxides; Organo-phosphine thioxides
- C07F9/5329—Polyphosphine oxides or thioxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5463—Compounds of the type "quasi-phosphonium", e.g. (C)a-P-(Y)b wherein a+b=4, b>=1 and Y=heteroatom, generally N or O
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/60—Reduction reactions, e.g. hydrogenation
- B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
- B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
- B01J2231/645—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/82—Metals of the platinum group
- B01J2531/822—Rhodium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55258604P | 2004-03-12 | 2004-03-12 | |
| US58651204P | 2004-07-09 | 2004-07-09 | |
| PCT/IB2005/000642 WO2005087370A1 (en) | 2004-03-12 | 2005-03-09 | C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1727620T3 true DK1727620T3 (da) | 2007-12-03 |
Family
ID=34961258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05708733T DK1727620T3 (da) | 2004-03-12 | 2005-03-09 | C1 symmetriske biphosphinlegander og deres anvendelse i asymmetrisk syntese af pregabilin |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20050228190A1 (de) |
| EP (1) | EP1727620B1 (de) |
| JP (1) | JP2007528893A (de) |
| KR (2) | KR100823758B1 (de) |
| AR (1) | AR051533A1 (de) |
| AT (1) | ATE371496T1 (de) |
| AU (1) | AU2005221401A1 (de) |
| BR (1) | BRPI0508615A (de) |
| CA (1) | CA2559086A1 (de) |
| CY (1) | CY1106877T1 (de) |
| DE (1) | DE602005002253T2 (de) |
| DK (1) | DK1727620T3 (de) |
| ES (1) | ES2292107T3 (de) |
| IL (1) | IL177482A0 (de) |
| NO (1) | NO20063574L (de) |
| NZ (1) | NZ549004A (de) |
| PL (1) | PL1727620T3 (de) |
| PT (1) | PT1727620E (de) |
| RU (1) | RU2335342C2 (de) |
| TW (1) | TWI299990B (de) |
| WO (1) | WO2005087370A1 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL126999A (en) | 1996-07-24 | 2002-03-10 | Warner Lambert Co | Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain |
| EP1866275A1 (de) | 2005-04-06 | 2007-12-19 | Teva Pharmaceutical Industries Ltd. | Kristalline formen des pregabalins |
| US7488846B2 (en) * | 2005-04-11 | 2009-02-10 | Teva Pharmaceuical Industries Ltd. | Pregabalin free of lactam and a process for preparation thereof |
| CA2603215A1 (en) * | 2005-04-11 | 2006-10-19 | Teva Pharmaceutical Industries Ltd. | Process for making (s)-pregabalin |
| US20070043241A1 (en) * | 2005-05-10 | 2007-02-22 | Lilach Hedvati | Optical resolution of 3-carbamoylmethyl-5-methylhexanoic acid |
| US7462737B2 (en) | 2005-05-10 | 2008-12-09 | Teva Pharmaceutical Industries Ltd. | Pregabalin free of isobutylglutaric acid and a process for preparation thereof |
| ATE486841T1 (de) * | 2005-05-10 | 2010-11-15 | Teva Pharma | Verfahren zur herstellung von pregabalin und salzen daraus |
| KR20070087596A (ko) * | 2005-09-19 | 2007-08-28 | 테바 파마슈티컬 인더스트리즈 리미티드 | (s)-(+)-3-(아미노메틸)-5-메틸헥산산의 비대칭 합성 |
| BRPI0702865A2 (pt) * | 2006-04-24 | 2012-08-07 | Teva Pharma | processos para preparaÇço do Ácido 3-isobutilglutÁrico e de (s)- pregabalin, a partir de combinaÇÕes de composiÇÕes com fàrmulas especÍficas para uso na dita preparaÇço |
| US7462738B2 (en) * | 2006-05-24 | 2008-12-09 | Teva Pharmaceutical Industries Ltd. | Processes for the preparation of R-(+)-3-(carbamoyl methyl)-5-methylhexanoic acid and salts thereof |
| EP1912931A2 (de) * | 2006-05-31 | 2008-04-23 | Teva Pharmaceutical Industries Ltd. | (s)-prägabalin-nitril-präparat |
| KR20080036060A (ko) * | 2006-05-31 | 2008-04-24 | 테바 파마슈티컬 인더스트리즈 리미티드 | 프레가발린의 중간체의 제조에 효소 분할을 이용하는 방법 |
| GB0700622D0 (en) * | 2007-01-12 | 2007-02-21 | Johnson Matthey Plc | Process for preparing cationic rhodium complexes |
| MX2008014759A (es) * | 2007-03-22 | 2009-03-09 | Teva Pharma | Sintesis del acido (s)-(+)-3-(aminometil)-5-metil hexanoico. |
| KR20090101462A (ko) * | 2007-10-03 | 2009-09-28 | 테바 파마슈티컬 인더스트리즈 리미티드 | 프레가발린-4-엘리미네이트, 프레가발린 5-엘리미네이트, 기준 마커 및 표준물로서의 이들의 용도, 및 이들을 낮은 수준으로 함유하는 프레가발린의 제조 방법 |
| US8546112B2 (en) | 2008-05-21 | 2013-10-01 | Sandoz Ag | Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester |
| US20100087525A1 (en) * | 2008-06-23 | 2010-04-08 | Lilach Hedvati | Stereoselective enzymatic synthesis of (s) or (r)-iso-butyl-glutaric ester |
| GB0812290D0 (en) * | 2008-07-04 | 2008-08-13 | Johnson Matthey Plc | Process for preparing cationic rhodium complexes |
| JP5750449B2 (ja) | 2009-11-05 | 2015-07-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規キラルリンリガンド |
| WO2011098160A1 (en) | 2010-02-12 | 2011-08-18 | Enantia, S.L. | Enantiomerically enriched aminodiphosphines as ligands for the preparation of catalysts for asymmetric synthesis |
| GB201103092D0 (en) * | 2011-02-23 | 2011-04-06 | Univ Dublin | Process |
| WO2016075082A1 (en) | 2014-11-10 | 2016-05-19 | Sandoz Ag | Stereoselective reductive amination of alpha-chiral aldehydes using omega-transaminases for the synthesis of precursors of pregabalin and brivaracetam |
| EP3551639B1 (de) | 2016-12-06 | 2023-08-23 | Boehringer Ingelheim International GmbH | Neuartige chirale dihydrobenzoazaphospholliganden und synthese davon |
| US10221203B2 (en) | 2016-12-06 | 2019-03-05 | Boehringer Ingelheim International Gmbh | Chiral dihydrobenzooxaphosphole ligands and synthesis thereof |
| JP6949903B2 (ja) | 2019-06-24 | 2021-10-13 | 日本化学工業株式会社 | 光学活性ビスホスフィノメタン及びその製造方法、並びに遷移金属錯体及び不斉触媒 |
| CN111647020A (zh) * | 2020-04-09 | 2020-09-11 | 宁波赜军医药科技有限公司 | 一种膦氧双齿配体的合成方法 |
| CN119707970A (zh) * | 2023-09-26 | 2025-03-28 | 中国科学院大连化学物理研究所 | 一种钯催化不对称氢化合成吲哚啉衍生物的方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6197819B1 (en) * | 1990-11-27 | 2001-03-06 | Northwestern University | Gamma amino butyric acid analogs and optical isomers |
| US5616793A (en) * | 1995-06-02 | 1997-04-01 | Warner-Lambert Company | Methods of making (S)-3-(aminomethyl)-5-methylhexanoic acid |
| US5637767A (en) * | 1995-06-07 | 1997-06-10 | Warner-Lambert Company | Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid |
| IL126999A (en) * | 1996-07-24 | 2002-03-10 | Warner Lambert Co | Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain |
| US6329429B1 (en) * | 1997-06-25 | 2001-12-11 | Warner-Lambert Company | Use of GABA analogs such as Gabapentin in the manufacture of a medicament for treating inflammatory diseases |
| AU9019198A (en) * | 1997-08-19 | 1999-03-08 | Warner-Lambert Company | Methods for treating physiological conditions associated with the use, or sequelae of use, of cocaine or other psychomotor stimulants |
| WO1999008670A1 (en) * | 1997-08-20 | 1999-02-25 | Guglietta, Antonio | Gaba analogs to prevent and treat gastrointestinal damage |
| US6127418A (en) * | 1997-08-20 | 2000-10-03 | Warner-Lambert Company | GABA analogs to prevent and treat gastrointestinal damage |
| EP1094817A1 (de) * | 1998-07-09 | 2001-05-02 | Warner-Lambert Company | Zusammensetzungen enthaltend gaba-analoge und koffein |
| WO2000002546A2 (en) * | 1998-07-09 | 2000-01-20 | Warner-Lambert Company | Use of caba-analogues for treating insomnia |
| CA2344407C (en) * | 1998-10-16 | 2007-01-09 | Warner-Lambert Company | Method for the treatment of mania and bipolar disorder |
| PT1250311E (pt) * | 2000-01-27 | 2004-07-30 | Warner Lambert Co | Sintese assimetrica de pregabalina |
| MXPA02001147A (es) * | 2001-03-19 | 2004-04-21 | Warner Lambert Co | Sintesis de ligandos bisfosina no-c2-simetricos como catalizadores para la hidrogenacion asimetrica. |
| US6696058B2 (en) * | 2002-01-29 | 2004-02-24 | Laclede, Inc. | Aqueous enzymatic denture adhesives |
| NI200300043A (es) * | 2002-03-28 | 2003-11-05 | Warner Lambert Co | AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA. |
-
2005
- 2005-03-09 RU RU2006132505/04A patent/RU2335342C2/ru not_active IP Right Cessation
- 2005-03-09 ES ES05708733T patent/ES2292107T3/es not_active Expired - Lifetime
- 2005-03-09 EP EP05708733A patent/EP1727620B1/de not_active Expired - Lifetime
- 2005-03-09 KR KR1020077014949A patent/KR100823758B1/ko not_active Expired - Fee Related
- 2005-03-09 DK DK05708733T patent/DK1727620T3/da active
- 2005-03-09 JP JP2007502434A patent/JP2007528893A/ja not_active Withdrawn
- 2005-03-09 AU AU2005221401A patent/AU2005221401A1/en not_active Abandoned
- 2005-03-09 AT AT05708733T patent/ATE371496T1/de not_active IP Right Cessation
- 2005-03-09 PT PT05708733T patent/PT1727620E/pt unknown
- 2005-03-09 KR KR1020067018522A patent/KR100847922B1/ko not_active Expired - Fee Related
- 2005-03-09 NZ NZ549004A patent/NZ549004A/en unknown
- 2005-03-09 DE DE602005002253T patent/DE602005002253T2/de not_active Expired - Fee Related
- 2005-03-09 BR BRPI0508615-9A patent/BRPI0508615A/pt not_active IP Right Cessation
- 2005-03-09 PL PL05708733T patent/PL1727620T3/pl unknown
- 2005-03-09 WO PCT/IB2005/000642 patent/WO2005087370A1/en not_active Ceased
- 2005-03-09 CA CA002559086A patent/CA2559086A1/en not_active Abandoned
- 2005-03-10 TW TW094107381A patent/TWI299990B/zh active
- 2005-03-10 AR ARP050100918A patent/AR051533A1/es active IP Right Grant
- 2005-03-11 US US11/078,228 patent/US20050228190A1/en not_active Abandoned
-
2006
- 2006-08-07 NO NO20063574A patent/NO20063574L/no not_active Application Discontinuation
- 2006-08-14 IL IL177482A patent/IL177482A0/en unknown
-
2007
- 2007-09-17 CY CY20071101203T patent/CY1106877T1/el unknown
-
2009
- 2009-01-14 US US12/353,450 patent/US20090124820A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2335342C2 (ru) | 2008-10-10 |
| DE602005002253T2 (de) | 2008-05-29 |
| WO2005087370A1 (en) | 2005-09-22 |
| RU2006132505A (ru) | 2008-03-27 |
| NO20063574L (no) | 2006-09-05 |
| DE602005002253D1 (de) | 2007-10-11 |
| CY1106877T1 (el) | 2012-09-26 |
| CA2559086A1 (en) | 2005-09-22 |
| PT1727620E (pt) | 2007-11-05 |
| KR20070074671A (ko) | 2007-07-12 |
| PL1727620T3 (pl) | 2007-12-31 |
| EP1727620A1 (de) | 2006-12-06 |
| NZ549004A (en) | 2009-04-30 |
| JP2007528893A (ja) | 2007-10-18 |
| ATE371496T1 (de) | 2007-09-15 |
| KR100847922B1 (ko) | 2008-07-22 |
| ES2292107T3 (es) | 2008-03-01 |
| IL177482A0 (en) | 2006-12-10 |
| AU2005221401A1 (en) | 2005-09-22 |
| TW200600090A (en) | 2006-01-01 |
| BRPI0508615A (pt) | 2007-07-31 |
| TWI299990B (en) | 2008-08-21 |
| US20050228190A1 (en) | 2005-10-13 |
| AR051533A1 (es) | 2007-01-24 |
| EP1727620B1 (de) | 2007-08-29 |
| KR100823758B1 (ko) | 2008-04-21 |
| KR20060118603A (ko) | 2006-11-23 |
| US20090124820A1 (en) | 2009-05-14 |
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