DK176177A - Fremgangsmade til fremstilling af phenylpiperaziner - Google Patents

Fremgangsmade til fremstilling af phenylpiperaziner

Info

Publication number
DK176177A
DK176177A DK176177A DK176177A DK176177A DK 176177 A DK176177 A DK 176177A DK 176177 A DK176177 A DK 176177A DK 176177 A DK176177 A DK 176177A DK 176177 A DK176177 A DK 176177A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
phenyl piperazines
piperazines
phenyl
Prior art date
Application number
DK176177A
Other languages
Danish (da)
English (en)
Inventor
J P Verge
W B Jamieson
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of DK176177A publication Critical patent/DK176177A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK176177A 1976-04-23 1977-04-21 Fremgangsmade til fremstilling af phenylpiperaziner DK176177A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB16526/76A GB1575904A (en) 1976-04-23 1976-04-23 Phenyl piperazines

Publications (1)

Publication Number Publication Date
DK176177A true DK176177A (da) 1977-10-24

Family

ID=10078930

Family Applications (1)

Application Number Title Priority Date Filing Date
DK176177A DK176177A (da) 1976-04-23 1977-04-21 Fremgangsmade til fremstilling af phenylpiperaziner

Country Status (34)

Country Link
JP (1) JPS52151183A (cs)
AR (2) AR222003A1 (cs)
AT (1) AT355579B (cs)
AU (1) AU514822B2 (cs)
BE (1) BE853899A (cs)
BG (2) BG28055A3 (cs)
CA (1) CA1087617A (cs)
CH (2) CH633009A5 (cs)
CS (1) CS196360B2 (cs)
DD (1) DD129790A5 (cs)
DE (1) DE2717415A1 (cs)
DK (1) DK176177A (cs)
ES (2) ES457988A1 (cs)
FI (1) FI63937C (cs)
FR (1) FR2348925A1 (cs)
GB (1) GB1575904A (cs)
GR (1) GR64084B (cs)
HU (1) HU176820B (cs)
IE (1) IE44730B1 (cs)
IL (1) IL51787A (cs)
LU (1) LU77170A1 (cs)
MX (1) MX4596E (cs)
NL (1) NL7704456A (cs)
NO (1) NO146710C (cs)
NZ (1) NZ183715A (cs)
OA (1) OA05643A (cs)
PH (1) PH14124A (cs)
PL (1) PL117466B1 (cs)
PT (1) PT66452B (cs)
RO (1) RO72831A (cs)
SE (1) SE7704536L (cs)
SU (2) SU664564A3 (cs)
YU (1) YU104477A (cs)
ZA (1) ZA771849B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1601310A (en) * 1978-05-23 1981-10-28 Lilly Industries Ltd Aryl hydantoins
DE3142608A1 (de) * 1981-10-28 1983-05-05 Basf Ag, 6700 Ludwigshafen Polyazofarbstoffe
JPH07157477A (ja) * 1993-12-02 1995-06-20 Asahi Kagaku Kogyo Kk チアゾール誘導体の製造方法
US5834499A (en) * 1994-03-11 1998-11-10 Yamanouchi Pharmaceutical Co., Ltd. 5-HT3 receptor agonist, novel thiazole derivative and intermediate thereof
CA2144669A1 (en) * 1994-03-29 1995-09-30 Kozo Akasaka Biphenyl derivatives
GB9517381D0 (en) * 1995-08-24 1995-10-25 Pharmacia Spa Aryl and heteroaryl piperazine derivatives
DZ3292A1 (fr) * 2001-09-13 2005-05-14 Solvay Pharm Gmbh Nouveaux composes de type 1-[1-(hetero)aryl-1-perhydroxyalkylmethyl]piperazine, methodes pour les preparer et medicaments renfermant cescomposes
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
US7829713B2 (en) * 2006-02-28 2010-11-09 Helicon Therapeutics, Inc. Therapeutic piperazines

Also Published As

Publication number Publication date
NO146710C (no) 1982-11-24
JPS52151183A (en) 1977-12-15
SU727146A3 (ru) 1980-04-05
ZA771849B (en) 1978-11-29
CA1087617A (en) 1980-10-14
PL117466B1 (en) 1981-08-31
CH633009A5 (en) 1982-11-15
FI771287A7 (cs) 1977-10-24
ES467948A1 (es) 1978-11-01
RO72831B (ro) 1983-07-30
AT355579B (de) 1980-03-10
PT66452A (en) 1977-05-01
FI63937B (fi) 1983-05-31
FR2348925B1 (cs) 1980-04-11
IL51787A (en) 1980-02-29
SU664564A3 (ru) 1979-05-25
LU77170A1 (cs) 1979-01-18
NO146710B (no) 1982-08-16
YU104477A (en) 1983-01-21
OA05643A (fr) 1981-04-30
CH625802A5 (en) 1981-10-15
BG28055A3 (bg) 1980-02-25
HU176820B (en) 1981-05-28
NL7704456A (nl) 1977-10-25
PH14124A (en) 1981-02-26
PL197550A1 (pl) 1979-05-21
MX4596E (es) 1982-06-25
FI63937C (fi) 1983-09-12
DD129790A5 (de) 1978-02-08
SE7704536L (sv) 1977-10-24
PT66452B (en) 1979-03-09
AR222635A1 (es) 1981-06-15
BE853899A (fr) 1977-10-24
GR64084B (en) 1980-01-21
CS196360B2 (en) 1980-03-31
ES457988A1 (es) 1978-07-16
NZ183715A (en) 1980-04-28
AU2438677A (en) 1978-10-26
BG27746A3 (bg) 1979-12-12
GB1575904A (en) 1980-10-01
RO72831A (ro) 1983-08-03
AU514822B2 (en) 1981-02-26
DE2717415A1 (de) 1977-11-10
ATA285177A (de) 1979-08-15
IE44730B1 (en) 1982-03-10
FR2348925A1 (fr) 1977-11-18
AR222003A1 (es) 1981-04-15
IL51787A0 (en) 1977-05-31
NO771398L (no) 1977-10-25
IE44730L (en) 1977-10-23

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Legal Events

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AHS Application shelved for other reasons than non-payment